18,383 results on '"A. Voisin"'
Search Results
52. Electroluminescence of the graphene 2D semi-metal
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Schmitt, A., Abou-Hamdan, L., Tharrault, M., Rossetti, S., Mele, D., Bretel, R., Pierret, A., Rosticher, M., Morfin, P., Taniguchi, T., Watanabe, K., Berroir, J. M., Fève, G., Ménard, G., Plaçais, B., Voisin, C., Hugonin, J. P., Greffet, J. J., Bouchon, P., De Wilde, Y., and Baudin, E.
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Electroluminescence, a non-thermal radiative process, is ubiquitous in semi-conductors and insulators but fundamentally precluded in metals. We show here that this restriction can be circumvented in high-quality graphene. By investigating the radiative emission of semi-metallic graphene field-effect transistors over a broad spectral range, spanning the near- and mid-infrared, we demonstrate direct far-field electroluminescence from hBN-encapsulated graphene in the mid-infrared under large bias in ambient conditions. Through a series of test experiments ruling out its incandescence origin, we determine that the electroluminescent signal results from the electrical pumping produced by interband tunneling. We show that the mid-infrared electroluminescence is spectrally shaped by a natural quarter-wave resonance of the heterostructure. This work invites a reassessment of the use of metals and semi-metals as non-equilibrium light emitters, and the exploration of their intriguing specificities in terms of carrier injection and relaxation, as well as emission tunability and switching speed., Comment: Main text (8 pages , 3 figures ) + Supplementary Information ( 19 pages , 19 figures)
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- 2023
53. Geometrical envelopes of fast radio bursts
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Voisin, Guillaume
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Aims. Assuming fast radio bursts (FRBs) are produced by matter travelling ultra-relativistically in a localised region of a smooth bundle of streamlines, we study the constraints applied by geometry to the morphology and polarisation of the burst in time and frequency independently of the intrinsic radiative process. Methods. We express the problem only in terms of the local properties of direction and curvature of a streamline. This allows us to cast the general results to any desired geometry. We illustrate by applying this framework to two geometries inspired by pulsar and magnetar magnetospheres, namely the dipolar polar-cap region and a magnetic dipole with an additional toroidal component. Results. Geometry constrains bursts to occur within an envelope in the frequency vs. time plane (dynamic spectrum). This envelope notably characterises spectral occupancy and frequency drifts (both burst-to-burst and within an individual burst). We illustrate how one can simulate bursts by specifying some basic properties of an intrinsic emission process. In particular we show that the typical properties of one-off bursts can be produced in polar-cap geometry by a star with spin period > 1s, while bursts from repeating sources are better accounted for with an additional strong toroidal component and a sub-second spin period. Conclusions. We propose that a relationship between burst morphologies and the properties of the source, such as its spin period and magnetospheric properties, can be established at least qualitatively based on geometrical considerations. Our results favour models where repeaters are younger and faster magnetars with highly twisted magnetospheres., Comment: Astronomy and Astrophysics - A&A, In press
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- 2023
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54. A telecom band single-photon source using a grafted carbon nanotube coupled to a fiber Fabry-Perot cavity in the Purcell regime
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Borel, Antoine, Habrant-Claude, Théo, Rapisarda, Federico, Reichel, Jakob, Doorn, Steeve, Voisin, Christophe, and Chassagneux, Yannick
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Quantum Physics - Abstract
We report on the coupling of a reconfigurable high Q fiber micro-cavity to an organic color center grafted to a carbon nanotube for telecom wavelength emission of single photons in the Purcell regime. Using three complementary approaches we assess various figures of merit of this tunable single photon source and of the cavity quantum electrodynamical effects : the brightening of the emitter is obtained by comparison of the count rates of the very same emitter in free-space and cavity coupled regimes. We demonstrate a fiber coupled single-photon output rate up to 20 MHz at 1275~nm. Using time-resolved and saturation measurements, we determine independently the radiative quantum yield and the Purcell factor of the system with values up to 30 for the smallest mode volumes. Finally, we take advantage of the tuning capability of the cavity to measure the spectral profile of the brightness of the source which gives access to the vacuum Rabi splitting $g$ with values up to $25 \; \mu$eV.
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- 2023
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55. On Chern classes of Lagrangian fibered hyper-K\'ahler manifolds
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Voisin, Claire
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Mathematics - Algebraic Geometry - Abstract
We study the rank stratification for the differential of a Lagrangian fibration over a smooth basis. We also introduce and study the notion of Lagrangian morphism of vector bundles. As a consequence, we prove some of the vanishing, in the Chow groups of a Lagrangian fibered hyper-K\"ahler variety $X$, of certain polynomials in the Chern classes of $X$ and the Lagrangian divisor, predicted by the Beauville-Voisin conjecture. Under some natural assumptions on the dimensions of the rank strata, we also establish nonnegativity and positivity results for Chern classes., Comment: Final version, to appear in PAMQ, memorial volume for Jean-Pierre Demailly
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- 2023
56. Symmetric tensors on the intersection of two quadrics and Lagrangian fibration
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Beauville, A., Etesse, A., Höring, A., Liu, J., and Voisin, C.
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Mathematics - Algebraic Geometry - Abstract
Let X be a n-dimensional (smooth) intersection of two quadrics, and let T*X be its cotangent bundle. We show that the algebra of symmetric tensors on X is a polynomial algebra in n variables. The corresponding map F: T*X -- > C^n is a Lagrangian fibration, which admits an explicit geometric description; its general fiber is a Zariski open subset of an abelian variety, quotient of a hyperelliptic Jacobian by a 2-torsion subgroup. For n = 3 F is the Hitchin fibration of the moduli space of rank 2 bundles with fixed determinant on a curve of genus 2.
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- 2023
57. Intrinsic Proteolytic Activities from Cancer Cells Are Sufficient to Activate Alkoxyamine Prodrugs and Induce Cell Death
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Marion Filliâtre, Seda Seren, Ange W. Embo-Ibouanga, Jean-Patrick Joly, Véronique Bouchaud, Ines Kelkoul, Sylvain R. A. Marque, Gérard Audran, Pierre Voisin, and Philippe Mellet
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Chemistry ,QD1-999 - Published
- 2024
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58. A comprehensive map of the aging blood methylome in humans
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Kirsten Seale, Andrew Teschendorff, Alexander P. Reiner, Sarah Voisin, and Nir Eynon
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Biology (General) ,QH301-705.5 ,Genetics ,QH426-470 - Abstract
Abstract Background During aging, the human methylome undergoes both differential and variable shifts, accompanied by increased entropy. The distinction between variably methylated positions (VMPs) and differentially methylated positions (DMPs), their contribution to epigenetic age, and the role of cell type heterogeneity remain unclear. Results We conduct a comprehensive analysis of > 32,000 human blood methylomes from 56 datasets (age range = 6–101 years). We find a significant proportion of the blood methylome that is differentially methylated with age (48% DMPs; FDR
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- 2024
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59. Future Orientation as a Moderator of Bullying Victimization and School Outcomes: Comparing Heterosexual and Sexual Minority Urban African American Adolescents
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Hong, Jun Sung, Wade, Ryan M., Kim, Jinwon, Espelage, Dorothy L., Washington, Tyreasa, and Voisin, Dexter R.
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Bullying victimization remains to be a public health concern in the United States, especially among sexual and ethnic minority youth. However, few studies have examined how school outcomes might be associated with bullying victimization among heterosexual and sexual minority African American youth and the factors that may attenuate that relationship. To address this gap, this study surveyed 462 heterosexual and 102 sexual minority African American youth residing in Chicago's Southside neighborhoods, who participated in the Resiliency Project. Study variables included bullying victimization, school outcomes (i.e., school connectedness, and academic grades), and future orientation. Bullying victimization was associated with a significant increase in feeling disconnected from school among both heterosexual and sexual minority adolescents; however, there was no significant association observed between bullying victimization and receiving low grades among either group. Future orientation did not moderate the association between bullying victimization and school outcomes among heterosexual adolescents; however, positive future orientation did attenuate the association between bullying victimization and feeling disconnected from school among sexual minority adolescents. Prevention programs that focus on promoting school connectedness need to consider the role of future orientation for sexual minority youth.
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- 2023
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60. The Fight is Two Times as Hard: A Qualitative Examination of a Violence Syndemic Among Young Black Sexual Minority Men.
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Dakin, Andrea, Bouacha, Nora, Valadez-Tapia, Silvia, Voisin, Dexter, Quinn, Katherine, Edwards, Travonne, Johnson, Anthony, Spector, Antoinette, and Takahashi, Lois
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Black gay and bisexual men ,HIV ,intersectionality ,mental health ,neighborhood violence ,Male ,Humans ,Homosexuality ,Male ,Sexual and Gender Minorities ,Syndemic ,Violence ,HIV Infections - Abstract
Young Black men who have sex with men (YBMSM) are disproportionately impacted by violence, including violence rooted in anti-Black racism, sexual identity bullying, and neighborhood violence rooted in structural racism and inequities. These multiple forms of violence are frequently co-occurring and interactive creating syndemic conditions that can negatively impact HIV care. This qualitative study is based on in-depth interviews with 31 YBMSM, aged 16-30 years, living with HIV in Chicago, IL, to examine how violence has impacted their lives. Using thematic analysis, we identified five themes that reflect how YBMSM experience violence at the intersection of racism, homonegativity, socioeconomic status, and HIV status: (a) the experience of intersectional violence; (b) long histories of violence contributed to hypervigilance, lack of safety, and lack of trust; (c) making meaning of violence and the importance of strength; (d) normalizing violence for survival; and (e) the cyclical nature of violence. Our study highlights how multiple forms of violence can accumulate across an individuals life and contribute to social and contextual situations that further contribute to violence and negatively impact mental health and HIV care.
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- 2023
61. Magneto-exciton limit of quantum Hall breakdown in graphene
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Schmitt, A., Rosticher, M., Taniguchi, T., Watanabe, K., Fève, G., Berroir, J-M., Ménard, G., Voisin, C., Goerbig, M. O., Plaçais, B., and Baudin, E.
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
One of the intrinsic drift velocity limit of the quantum Hall effect is the collective magneto-exciton (ME) instability. It has been demonstrated in bilayer graphene (BLG) using noise measurements. We reproduce this experiment in monolayer graphene (MLG), and show that the same mechanism carries a direct relativistic signature on the breakdown velocity. Based on theoretical calculations of MLG- and BLG-ME spectra, we show that Doppler-induced instabilities manifest for a ME phase velocity determined by a universal value of the ME conductivity, set by the Hall conductance., Comment: 27 pages, 11 figures including supplementary information (14 pages and 3 figures for the main text alone)
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- 2023
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62. High-field 1/f noise in hBN-encapsulated graphene transistors
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Schmitt, A., Mele, D., Rosticher, M., Taniguchi, T., Watanabe, K., Maestre, C., Journet, C., Garnier, V., Fève, G., Berroir, J. M., Voisin, C., Plaçais, B., and Baudin, E.
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Low-frequency 1/f noise in electronics is a conductance fluctuation, that has been expressed in terms of a mobility "$\alpha$-noise" by Hooge and Kleinpenning. Understanding this noise in graphene is a key towards high-performance electronics. Early investigations in diffusive graphene have pointed out a deviation from the standard Hooge formula, with a modified expression where the free-carrier density is substituted by a constant density $n_\Delta\sim10^{12}\;\mathrm{cm^{-2}}$. We investigate hBN-encapsulated graphene transistors where high mobility gives rise to the non-linear velocity-saturation regime. In this regime, the $\alpha$-noise is accounted for by substituting conductance by differential conductance $G$, ressulting in a bell-shape dependence of flicker noise with bias voltage $V$. The same analysis holds at larger bias in the Zener regime, with two main differences: the first one is a strong enhancement of the Hooge parameter reflecting the hundred-times larger coupling of interband excitations to the hyperbolic phonon-polariton (HPhP) modes of the mid-infrared Reststrahlen (RS) bands of hBN. The second is an exponential suppression of this coupling at large fields, which we attribute to decoherence effects. We also show that the HPhP bands control the amplitude of flicker noise according to the graphene-hBN thermal coupling estimated with microwave noise thermometry. The phenomenology of $\alpha$-noise in graphene supports a quantum-coherent bremsstrahlung interpretation of flicker noise., Comment: v2, main + SI, added reference to open data on Zenodo repository
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- 2023
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63. Neutron star mass estimates from gamma-ray eclipses in spider millisecond pulsar binaries
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Clark, C. J., Kerr, M., Barr, E. D., Bhattacharyya, B., Breton, R. P., Bruel, P., Camilo, F., Chen, W., Cognard, I., Cromartie, H. T., Deneva, J., Dhillon, V. S., Guillemot, L., Kennedy, M. R., Kramer, M., Lyne, A. G., Sánchez, D. Mata, Nieder, L., Phillips, C., Ransom, S. M., Ray, P. S., Roberts, M. S. E., Roy, J., Smith, D. A., Spiewak, R., Stappers, B. W., Tabassum, S., Theureau, G., and Voisin, G.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Reliable neutron star mass measurements are key to determining the equation-of-state of cold nuclear matter, but these are rare. "Black Widows" and "Redbacks" are compact binaries consisting of millisecond pulsars and semi-degenerate companion stars. Spectroscopy of the optically bright companions can determine their radial velocities, providing inclination-dependent pulsar mass estimates. While inclinations can be inferred from subtle features in optical light curves, such estimates may be systematically biased due to incomplete heating models and poorly-understood variability. Using data from the Fermi Large Area Telescope, we have searched for gamma-ray eclipses from 49 spider systems, discovering significant eclipses in 7 systems, including the prototypical black widow PSR B1957$+$20. Gamma-ray eclipses require direct occultation of the pulsar by the companion, and so the detection, or significant exclusion, of a gamma-ray eclipse strictly limits the binary inclination angle, providing new robust, model-independent pulsar mass constraints. For PSR B1957$+$20, the eclipse implies a much lighter pulsar ($M_{\rm psr} = 1.81 \pm 0.07\,M_{\odot}$) than inferred from optical light curve modelling., Comment: 31 pages, 4 figures, includes supplementary tables; published in Nature Astronomy
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- 2023
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64. Spectral fingerprint of quantum confinement in single CsPbBr$_3$ nanocrystals
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Amara, Mohamed-Raouf, Said, Zakaria, Huo, Caixia, Pierret, Aurélie, Voisin, Christophe, Gao, Weibo, Xiong, Qihua, and Diederichs, Carole
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Lead halide perovskite nanocrystals are promising materials for classical and quantum light emission. To understand these outstanding properties, a thorough analysis of the band-edge exciton emission is needed which is not reachable in ensemble and room temperature studies because of broadening effects. Here, we report on a cryogenic-temperature study of the photoluminescence of single CsPbBr$_3$ NCs in the intermediate quantum confinement regime. We reveal the size-dependence of the spectral features observed: the bright-triplet exciton energy splittings, the trion and biexciton binding energies as well as the optical phonon replica spectrum. In addition, we show that bright triplet energy splittings are consistent with a pure exchange model and that the variety of polarisation properties and spectra recorded can be rationalised simply by considering the orientation of the emitting dipoles and the populations of the emitting states.
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- 2023
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65. A black widow population dissection through HiPERCAM multi-band light curve modelling
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Sánchez, D. Mata, Kennedy, M. R., Clark, C. J., Breton, R. P., Dhillon, V. S., Voisin, G., Camilo, F., Littlefair, S., Marsh, T. R., and Stringer, J.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Black widows are extreme millisecond pulsar binaries where the pulsar wind ablates their low-mass companion stars. Their optical light curves vary periodically due to the high irradiation and tidal distortion of the companion, which allows us to infer the binary parameters. We present simultaneous multi-band observations obtained with the HIPERCAM instrument at the 10.4-m GTC telescope for six of these systems. The combination of this five-band fast photometer with the world's largest optical telescope enables us to inspect the light curve range near minima. We present the first light curve for PSR J1641+8049, as well as attain a significant increase in signal-to-noise and cadence compared with previous publications for the remaining 5 targets: PSR J0023+0923, PSR J0251+2606, PSR J0636+5129, PSR J0952-0607 and PSR J1544+4937. We report on the results of the light curve modelling with the Icarus code for all six systems, which reveals some of the hottest and densest companion stars known. We compare the parameters derived with the limited but steadily growing black widow population for which optical modelling is available. We find some expected correlations, such as that between the companion star mean density and the orbital period of the system, but also a puzzling positive correlation between the orbital inclination and the irradiation temperature of the companion. We propose such a correlation would arise if pulsars with magnetic axis orthogonal to their spin axis are capable of irradiating their companions to a higher degree., Comment: 18 pages (+12 pages for appendix), 12 figures (+13 in the appendix), 3 tables (1 in the appendix). Accepted for publication in MNRAS on 2023 January 17th
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- 2023
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66. Light transmission aggregometry for platelet function testing: position paper on current recommendations and French proposals for accreditation
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Alain Stépanian, Florence Fischer, Claire Flaujac, Valérie Eschwège, Céline Delassasseigne, Léna Leflem, Frédéric Loridon, Sophie Voisin, and Dominique Lasne
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Accreditation ,laboratory practice ,light transmission aggregometry ,platelet ,Diseases of the blood and blood-forming organs ,RC633-647.5 - Abstract
Light transmission aggregometry (LTA) is a method used to investigate platelet functions in platelet-rich plasma (PRP), notably when screening for platelet disorders. Various national guidelines and recommendations help in setting up the LTA test in specialized laboratories. However, due to the nature of the sample matrix and its subsequent specificities, more accurate positions are needed to achieve LTA accreditation according to the standard NF EN ISO 15 189. We reviewed guidelines and recommendations as they can be useful in the accreditation process, and we conducted a survey on LTA practice among members of the Société Française de Thrombose et d’Hémostase (SFTH) in 2021. We formulated 28 proposals, which have been approved by vote within the SFTH. All aspects to take into consideration for the proper conduct of LTA assays and their accreditation have been covered. Notably, preanalytical, analytical and postanalytical aspects are depicted, including blood sampling, PRP preparation, instruments, agonists, performance assessment, personnel training and data interpretation. This document, essentially representing a French position paper on the current recommendations and subsequent proposals for LTA accreditation, might prove useful also outside France for relevant laboratories and auditors involved in LTA accreditation.
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- 2024
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67. Active and Passive Offline Breaks Differentially Impact the Consolidation of Procedural Motor Memories in Children and Adults
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D. Voisin, P. Peigneux, and C. Urbain
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
ABSTRACT Introduction Short post‐learning breaks, lasting from 5 to 30 min, transiently enhance procedural motor memory performance in adults. However, the impact of activity type (active vs. passive) during the offline break on sequential motor performance remains poorly investigated in children. Method This study examined the impact of active versus passive post‐learning breaks on procedural motor memory in 116 healthy participants (58 children, aged 9.03 ± 1.19; 58 adults, aged 22.89 ± 1.77 years). Participants practiced a Finger Tapping Task, reproducing a five‐element keypress sequence as fast and accurately as possible. The task included two sessions (S1 and S2) separated by either a short (30 min) or long (4 h) break. The first 30‐min of the post‐learning break included either a passive (remaining still) or an active (engaging in daily activities) condition. Results Repeated‐measures ANOVA revealed significant Session × Age group × Break duration and Session × Break type interaction effects (ps
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- 2024
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68. Identifying Robust Decarbonization Pathways for the Western U.S. Electric Power System Under Deep Climate Uncertainty
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Srihari Sundar, Flavio Lehner, Nathalie Voisin, and Michael T. Craig
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robust decision‐making ,power system planning ,capacity expansion ,resource adequacy ,single model initial‐condition large ensemble ,climate adaptation ,Environmental sciences ,GE1-350 ,Ecology ,QH540-549.5 - Abstract
Abstract Climate change threatens the resource adequacy of future power systems. Existing research and practice lack frameworks for identifying decarbonization pathways that are robust to climate‐related uncertainty. We create such an analytical framework, then use it to assess the robustness of alternative pathways to achieving 60% emissions reductions from 2022 levels by 2040 for the Western U.S. power system. Our framework integrates power system planning and resource adequacy models with 100 climate realizations from a large climate ensemble. Climate realizations drive electricity demand; thermal plant availability; and wind, solar, and hydropower generation. Among five initial decarbonization pathways, all exhibit modest to significant resource adequacy failures under climate realizations in 2040, but certain pathways experience significantly less resource adequacy failures at little additional cost relative to other pathways. By identifying and planning for an extreme climate realization that drives the largest resource adequacy failures across our pathways, we produce a new decarbonization pathway that has no resource adequacy failures under any climate realizations. This new pathway is roughly 5% more expensive than other pathways due to greater capacity investment, and shifts investment from wind to solar and natural gas generators. Our analysis suggests modest increases in investment costs can add significant robustness against climate change in decarbonizing power systems. Our framework can help power system planners adapt to climate change by stress testing future plans to potential climate realizations, and offers a unique bridge between energy system and climate modeling.
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- 2024
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69. On Leakage of Code Generation Evaluation Datasets.
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Alexandre Matton, Tom Sherborne, Dennis Aumiller, Elena Tommasone, Milad Alizadeh, Jingyi He, Raymond Ma, Maxime Voisin, Ellen Gilsenan-McMahon, and Matthias Gallé
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- 2024
70. Semantics Formalisation - From Event-B Contexts to Theories.
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Thai Son Hoang, Laurent Voisin, Karla Vanessa Morris Wright, Colin F. Snook, and Michael J. Butler
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- 2024
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71. Weather Sensitive High Spatio-Temporal Resolution Transportation Electric Load Profiles For Multiple Decarbonization Pathways.
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Samrat Acharya, Malini Ghosal, Travis Thurber, Casey D. Burleyson, Yang Ou, Allison Campbell, Gokul Iyer, Nathalie Voisin, and Jason Fuller
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- 2024
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72. Efficient Uniform Sampling of Traces in Presence of Infeasibilities
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Gaudel, M.-C., Voisin, F., Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Cavalcanti, Ana, editor, and Baxter, James, editor
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- 2024
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73. Semantics Formalisation – Modelling and Proving Strategies Using Event-B Versus Theories
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Hoang, Thai Son, Snook, Colin, Morris Wright, Karla Vanessa, Voisin, Laurent, Butler, Michael, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Foster, Simon, editor, and Sampaio, Augusto, editor
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- 2024
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74. Semantics Formalisation – From Event-B Contexts to Theories
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Hoang, Thai Son, Voisin, Laurent, Wright, Karla Vanessa Morris, Snook, Colin, Butler, Michael, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Bonfanti, Silvia, editor, Gargantini, Angelo, editor, Leuschel, Michael, editor, Riccobene, Elvinia, editor, and Scandurra, Patrizia, editor
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- 2024
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75. Possible Qualification Pathways for In Silico Methodologies
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Viceconti, Marco, Serigado, Alexandre, Rousseau, Cécile F., Voisin, Emmanuelle M., Viceconti, Marco, editor, and Emili, Luca, editor
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- 2024
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76. Possible Health Technology Assessment Pathways
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Carreras, Mireia Espallargues, Cuscó, Xavier Garcia, Alessandrello, Rossana, Maspons, Ramon, Serigado, Alexandre, Rousseau, Cécile F., Voisin, Emmanuelle M., Morales-Orcajo, Enrique, Viceconti, Marco, Viceconti, Marco, editor, and Emili, Luca, editor
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- 2024
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77. Ethical Review of In Silico Methodologies
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Rousseau, Cécile F., Voisin, Emmanuelle M., Poluzzi, Elisabetta, Serigado, Alexandre, Viceconti, Marco, Jori, Maria Cristina, Viceconti, Marco, editor, and Emili, Luca, editor
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- 2024
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78. Cycle classes on abelian varieties and the geometry of the Abel-Jacobi map
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Voisin, Claire
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Mathematics - Algebraic Geometry - Abstract
We discuss two properties of an abelian variety, namely, being a direct summand in a product of Jacobians and the weaker property of being "split". We relate the first property to the integral Hodge conjecture for curve classes on abelian varieties. We also relate both properties to the existence problem for universal zero-cycles on Brauer-Severi varieties over abelian varieties. A similar relation is established for the existence problem of a universal codimension 2 cycle on a cubic threefold., Comment: Minor revision
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- 2022
79. Status of QUBIC, the Q&U Bolometer for Cosmology
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Mousset, L., Ade, P., Almela, A., Amico, G., Arnaldi, L. H., Aumont, J., Banfi, S., Battistelli, E. S., Bélier, B., Bergé, L., Bernard, J. -Ph., de Bernardis, P., Bersanelli, M., Bonaparte, J., Bonilla, J. D., Bunn, E., Buzi, D., Camilieri, D., Cavaliere, F., Chanial, P., Chapron, C., Colombo, S., Columbro, F., Coppolecchia, A., Costanza, B., DÁlessandro, G., De Gasperis, G., De Leo, M., De Petris, M., Del Castillo, N., Dheilly, S., Etchegoyen, A., Famá, M., Ferreyro, L. P., Franceschet, C., Lerena, M. M. Gamboa, Ganga, K. M., García, B., Redondo, M. E. García, Gayer, D., Geria, J. M., Gervasi, M., Giard, M., Gilles, V., Berisso, M. Gómez, González, M., Gradziel, M., Grandsire, L., Hamilton, J. -Ch., Hampel, M. R., Isopi, G., Kaplan, J., Kristukat, C., Lamagna, L., Lazarte, F., Loucatos, S., Mancilla, A., Mandelli, D., Manzan, E., Marnieros, S., Marty, W., Masi, S., May, A., Maya, J., McCulloch, M., Mele, L., Melo, D., Mennella, A., Mirón-Granese, N., Montier, L., Müller, N., Murphy, J. D., Nati, F., OŚullivan, C., Paiella, A., Pajot, F., Paradiso, S., Passerini, A., Pelosi, A., Perciballi, M., Pezzotta, F., Piacentini, F., Piat, M., Piccirillo, L., Pisano, G., Platino, M., Polenta, G., Prêle, D., Rambaud, D., Rasztocky, E., Régnier, M., Reyes, C., Rodríguez, F., Rodríguez, C. A., Romero, G. E., Salum, J. M., Schillaci, A., Scóccola, C. G., Stankowiak, G., Supanitsky, A. D., Tartari, A., Thermeau, J. -P., Timbie, P., Torchinsky, S. A., Tucker, G., Tucker, C., Vacher, L., Voisin, F., Wright, M., Zannoni, M., and Zullo, A.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
The Q&U Bolometric Interferometer for Cosmology (QUBIC) is a novel kind of polarimeter optimized for the measurement of the B-mode polarization of the Cosmic Microwave Back-ground (CMB), which is one of the major challenges of observational cosmology. The signal is expected to be of the order of a few tens of nK, prone to instrumental systematic effects and polluted by various astrophysical foregrounds which can only be controlled through multichroic observations. QUBIC is designed to address these observational issues with a novel approach that combines the advantages of interferometry in terms of control of instrumental systematics with those of bolometric detectors in terms of wide-band, background-limited sensitivity., Comment: Contribution to the 2022 Cosmology session of the 33rd Rencontres de Blois. arXiv admin note: substantial text overlap with arXiv:2203.08947
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- 2022
80. The Inherent Violence of Anti-Black Racism and its Effects on HIV Care for Black Sexually Minoritized Men
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Quinn, Katherine G., Walsh, Jennifer L., DiFranceisco, Wayne, Edwards, Travonne, Takahashi, Lois, Johnson, Anthony, Dakin, Andrea, Bouacha, Nora, and Voisin, Dexter R.
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- 2024
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81. Religiosity and Associations with Substance Use and Delinquency Among Urban African American Adolescents
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Fairclough, Javari, Abd-Elmonem, Mohamed, Merrin, Gabriel J., Hong, Jun Sung, and Voisin, Dexter R.
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- 2024
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82. Structural and mechanistic insights into pore formation by proteins of the membrane attack complex/perforin superfamily
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Voisin, Tomas B. and Bubeck, Doryen
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Members of the membrane attack complex/perforin (MACPF) superfamily of pore-forming proteins are characterised by a common three-dimensional fold able to puncture lipid membranes. They are found in bacterial and eukaryotes, and include immune effectors, toxins and pathogenic virulence factors. Their conserved pore-forming domain follows the same mechanism whereby two bundles of α-helices unfurl into membrane-spanning β-hairpins. This thesis provides insights into the effects of MACPF proteins on biological membranes. Coarse-grain molecular dynamics simulations of the membrane attack complex (MAC) bound to its inhibitor CD59 reveal protein-lipid interactions and local changes in membrane thickness. These may serve as signals to recruit CD59 or the molecular machinery for MAC clearance. Some bacterial MACPF proteins called cholesterol-dependent cytolysins (CDCs) hijack CD59 on human cells as part of their pore formation pathway. Atomistic simulations of CD59 in a lipid bilayer show that it samples various orientations relative to the membrane, dictating whether its binding site is available for engaging MAC or CDCs, and thus for inhibiting or promoting pore formation. CDCs assemble on cholesterol-rich lipid membranes and undergo sequential conformational changes to puncture bilayers. Site-directed mutagenesis of two CDCs reveals that an amphipathic helix in the pore-forming helical bundles is responsible for tuning the lytic activity of these proteins. Understanding the molecular basis for the function of this helix will require the high-resolution structure of a CDC late prepore intermediate. The first steps towards solving this structure by cryo-electron microscopy are presented in this thesis.
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- 2023
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83. Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles
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Sissy Bassani, Jacqueline Chrast, Giovanna Ambrosini, Norine Voisin, Frédéric Schütz, Alfredo Brusco, Fabio Sirchia, Lydia Turban, Susanna Schubert, Rami Abou Jamra, Jan-Ulrich Schlump, Desiree DeMille, Pinar Bayrak-Toydemir, Gary Rex Nelson, Kristen Nicole Wong, Laura Duncan, Mackenzie Mosera, Christian Gilissen, Lisenka E. L. M. Vissers, Rolph Pfundt, Rogier Kersseboom, Hilde Yttervik, Geir Åsmund Myge Hansen, Marie Falkenberg Smeland, Kameryn M. Butler, Michael J. Lyons, Claudia M. B. Carvalho, Chaofan Zhang, James R. Lupski, Lorraine Potocki, Leticia Flores-Gallegos, Rodrigo Morales-Toquero, Florence Petit, Binnaz Yalcin, Annabelle Tuttle, Houda Zghal Elloumi, Lane McCormick, Mary Kukolich, Oliver Klaas, Judit Horvath, Marcello Scala, Michele Iacomino, Francesca Operto, Federico Zara, Karin Writzl, Aleš Maver, Maria K. Haanpää, Pia Pohjola, Harri Arikka, Anneke J. A. Kievit, Camilla Calandrini, Christian Iseli, Nicolas Guex, and Alexandre Reymond
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Mesomelic dysplasia ,Horseshoe kidney ,Intellectual disability ,Transcriptome ,Zebrafish model ,Medicine ,Genetics ,QH426-470 - Abstract
Abstract Background We previously described the KINSSHIP syndrome, an autosomal dominant disorder associated with intellectual disability (ID), mesomelic dysplasia and horseshoe kidney, caused by de novo variants in the degron of AFF3. Mouse knock-ins and overexpression in zebrafish provided evidence for a dominant-negative mode of action, wherein an increased level of AFF3 resulted in pathological effects. Methods Evolutionary constraints suggest that other modes-of-inheritance could be at play. We challenged this hypothesis by screening ID cohorts for individuals with predicted-to-be damaging variants in AFF3. We used both animal and cellular models to assess the deleteriousness of the identified variants. Results We identified an individual with a KINSSHIP-like phenotype carrying a de novo partial duplication of AFF3 further strengthening the hypothesis that an increased level of AFF3 is pathological. We also detected seventeen individuals displaying a milder syndrome with either heterozygous Loss-of-Function (LoF) or biallelic missense variants in AFF3. Consistent with semi-dominance, we discovered three patients with homozygous LoF and one compound heterozygote for a LoF and a missense variant, who presented more severe phenotypes than their heterozygous parents. Matching zebrafish knockdowns exhibit neurological defects that could be rescued by expressing human AFF3 mRNA, confirming their association with the ablation of aff3. Conversely, some of the human AFF3 mRNAs carrying missense variants identified in affected individuals did not rescue these phenotypes. Overexpression of mutated AFF3 mRNAs in zebrafish embryos produced a significant increase of abnormal larvae compared to wild-type overexpression further demonstrating deleteriousness. To further assess the effect of AFF3 variation, we profiled the transcriptome of fibroblasts from affected individuals and engineered isogenic cells harboring + / + , KINSSHIP/KINSSHIP, LoF/ + , LoF/LoF or KINSSHIP/LoF AFF3 genotypes. The expression of more than a third of the AFF3 bound loci is modified in either the KINSSHIP/KINSSHIP or the LoF/LoF lines. While the same pathways are affected, only about one third of the differentially expressed genes are common to the homozygote datasets, indicating that AFF3 LoF and KINSSHIP variants largely modulate transcriptomes differently, e.g. the DNA repair pathway displayed opposite modulation. Conclusions Our results and the high pleiotropy shown by variation at this locus suggest that minute changes in AFF3 function are deleterious.
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- 2024
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84. Effect of decentralising childhood tuberculosis diagnosis to primary health centre versus district hospital levels on disease detection in children from six high tuberculosis incidence countries: an operational research, pre-post intervention study
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Laurence, Borand, Agathe, de Lauzanne, Bunnet, Dim, Seyla, Heang, Sanary, Kaing, Chanty, Keang, Socheat, L.Y., Pichpiseth, Meas, Sovann, Nhoueng, Long, Pring, Vouchleang, Sreng, Song, Yin, Saren, Sovan, Chanvirak, Phan, Chanra, Chreng, Ratha, Khoun, Monicando, Rin, Sophea, Pal, Boraneath, Nang, Rathakrun, Pom, Tan Eang, Mao, Simoy, Chhim, Huot, Touch, Kosal, Suon, Saronn, Chum, Kimhong, Tok, Kimchorn, Pring, Satya, Krouch, Chean, Chok, Sunleng, Seun, Savtey, Phon, Mai, Nang, Kimda, Hun, Vanny, Hong, Dara, Sok, Kosal, Chea, Bunthoeun, Chheang, Rino, Sem, Lam, Lay, Haysan, Say, Pholly, Kem, Sreyphal, Meng, Sokheng, Phorn, Sreyvann, Him, Peakdey, Pheach, Dalai, Kive, Moeur, Sar, Sreydy, Kong, Seyha, Kong, Sreytouch, Yorn, Soam, Tes, Sophal, Kep, Seroeung HENG Thy, Leng, Savorn, Neak, Sim, Seng, Pheakna, Pay, Sithan, Suon, Sophanna, Chan, Dyna, Um, Savuth, Sin, Sam, Phan, Sarim, Kum, Sokheng, Khath, Pong, Phem, Seyha, Sok, Chanty, Ny, Van, Leim, Sereyvuth, Pich, Sengkry, Chheang, Nhin, Eang, Vannareth, Sao, Vannak, Sim, Sopheak, Som, Ney, Pong, Sokha, Van, Sreyleap, Seng, Vanna, Yoeurng, Kakada, Toem, Thida, Keo, Vuochny, Sem, Sophal, Veng, Chanthol, Rin, Vanny, Seang, Kiri, Lok, Khemra, Mao, Keovanna, Ouk, Maiya, Min, Suomun, Morm, Rattana, Koy, Sreypov, Chhann, Sreytouch, Set, Audrey, Amboua Schouame, Clifford, Babey, Masama, Eden Ngu, Etienne, Guenou, Sylvie, Kwedi Nolna, Douglas, Mbang Massom, Bernard Fortune, Melingui, Nadia, Nga Elomo, Moïse, Mvetumbo, Angeline, Nkembe, Krystel, Ebo, Albert, Kuate Kuate, Michelline, Choupa, Maggi, Mbede, Valerie, Donkeng, Nelly, Kamgaing, Jean-Voisin, Taguebue, Achille, Touha Yannick, Estelle, Abomo Zang, Rosette, Bakoa, Esperance, Mimbouombela Leger, Sabine, Eleme, Gabrielle, Eteme Marie, Thierry, Elouna Nkoa, Dieudonné, Ndzana, Christophe, Bitti, Olivier, Fotsing, Charlotte, Lani Boko, Mathieu, Mbonga, Ghislain Ulrich, Njakou Sagang, Innocent, Onomo, Charlotte, Essaga Hortense, Daniel Desiré, Mboudi Kouang, Léon, Eloundou, Helene, Kengne, Felix, Mbassi, Juliette, Bidjeme, Hortense, Toua Eteme, Nadege, Essama, Roger, Belinga Balla, Norbert, Tassi, Roline, Nguiko Elsa, Leonard, Mekongo, Fabien, Eyebe Ayissi, Francine Christelle, Biloa Anaba, Philomène, Nsom, Celestin Géraud, Yam Essola, Edwige Léa, Mame Moo, Noé, Makon, Arllette Rita, Nounkep Yanghu, Frank, Ebanga, Antoinette, Assiga Ntsama, Carlyle Sorelle, Kamguia Djuimsop, Diane, Mbabou, Marie, Maguip Abanda, Rosine Berthe, Nguemafouo Doummene, Amos, Mekone, Ngwankfu, Konfor Blessing, Jérome, Mimboe, Virginie, Tiona, Roland, Beleck, Sairou, Zam, Nicole, Adibone, Claude, Biaback Jean, Denis, Bessong, Gilbert, Aminou, Jeremie Pagnol, Bille Bonga, Aubin, Fotso Monkap, Epse NGON Annie, Hitekelek, Vitrice, Sebe, Leo, Makon, Marie, Ennah, Mpie, Paul Boyolo, Diane Viviane, Metchoum, Celin, Nzambe, Arnaud, Dado, Milobert, Mbengang, Marceline, Eyebi, Vanessa, Ngah, Alice, Mballa Batonga, Solange, Ayouba, Pierrette, Ebode, Majino, Mamou, Marguerite, Botomogne Bomba, Salametou, Ngnet, Augustine Florence, Essengue Ngono, Rolland, Odionoloba Charles, Bernice, Bisso, Suzy, Balemaken Ingrid, Marie Louise, Mandoki a Bilong, Gertrude, Ndeng Ayouba, Josue, Ngon, Roger, Aka Bony, Kacou Michel, Bah, Dro, Bakayoko, Rolande, Baki Aimee, Marie-France Larissa, Banga, Olivier, Bouzié, Kan, Brou, Pan, Coulibaly, Serge, Danho, Flavien, Deli, Alphonse, Dion, Bi, Do, Armand, Dohoun, William, Edjeme, Cathérine, Falé, Melissa, Gogoua Saulé, Constant, Kesse, Eric, Komena Auguste, Christian, Kouadio, Arkason, Kouame Abel, Raoul, Moh, Sandrine, Nguessan Marcelle, Bertine, Siloué, Nina, Soua, Cyrille Prisca, Yao Yapi, Timothée, Ouassa, Jacquemin, Kouakou, Eric, Balestre, Aurélie, Beuscart, Aurélie, Charpin, Marc, D'elbee, Hélène, Font, Basant, Joshi, Nicolas, Koskas, Olivier, Marcy, Estelle, Occelli, Joanna, Orne-Gliemann, Julien, Poublan, Elodie, Vernoux, Maryline, Bonnet, Savine, Chauvet, Manon, Lounnas, Guillaume, Breton, Pierre-Yves, Norval, Sheyla, Cassy, Verna, Chambal, Valter, Chiúle, Supinho, Chimbanje, Saniata, Cumbe, Mércia, Matsinhe, Celso, Khosa, Nairo, Mabote, Salvador, Machava, Emelva, Machonisse, Verónica, Macuácua, Denise, Milice, Jorge, Ribeiro, Elcídio, Tivane, Dorlim, Uetela, Yara, Voss de Lima, Américo, Zandamela, Alcina, Zita, Ivan, Manhiça, Benedita, José, Dalila, Rego, Chris, Buck W., Kapoli, Kasembe, Atália, Massangaie, Assa, Sitoe, Ambostique, Argola, Césio, Miambo, Presequila, Nhatsave, Gilda, Sitoe, Charifito, Vesta, Salvador, Dimande, Lázaro, Mazembe, Nilza, Amade, Manuela, Chavela, Nomsa, Macheque, Salomão, Comé, Eulália, Machava, Narciso, Mucavele, Jacinto, Nhabanga, Marlene, Nicolau, Natércia, Simbine, Lina, Uendela, Micaela, Juaio, Abiba, Saíde, Naira, Macie, Fernando, Mondlane, Stélio, Simango, Prince, Beyan, Benjamin M, Flomo, Abubakarr, Jalloh Joseph, Ishmael, Kamara, Monica G, Koroma, Mohamed, Lamin, Lena, Matata, Ross, Mugisha Jacob, Christiana M, Senesie, Sheriff, S.E.S.A.Y., Egerton, Tamba Kamara, Ayeshatu, Mustapha, Lynda, Foray, Sandra, Agondeze, Agnes, Kobusingye, Mastula, Nanfuka, Faith, Namulinda, Eric, Wobudeya, Rinah, Arinaitwe, Rodney, Kaitano, Martin, Kasujja, Juliet, Mwanga-Amumpaire, Evans, Mwesigwa, Naome, Natukunda, Simpson, Nuwamanya, Miria, Nyangoma, Patrick, Orikiriza, Johnbosco, Tumwijukye, Esther, Turyashemererwa, Nyehangane, Dan, Mugisha, Ivan, Winnie, Biryeri, George, Naika, Robert, Ongwara O., Allen, Najjuko, Augustine, Kayiira, Samuel, Yairo, Immaculate, Tumwebaze, Goreth, Nalwoga, Paul, Nsiyaleta, Annet, Agaba, Martin, Mpimbaza M., Norbert, Akampurira, Agatha, Tugumisirize, Evans, Ariyo, Julius, Agaba, Yovita, Natukunda, Nelson, Musazi, Edmund, Musinguzi, Brown, Baluku Julius, Moorine, Sekadde, Stavia, Turyahabwe, Chishala, Chabala, Luis, Cuevas, Christophe, Delacourt, Steve, Graham, Malgorzata, Grzemska, Sabine, Verkuijl, Anneke, Hesseling, Elizabeth, Maleche-Obimbo, Mark, Nicol, Wobudeya, Eric, Nanfuka, Mastula, Ton Nu Nguyet, Minh Huyen, Taguebue, Jean-Voisin, Moh, Raoul, Breton, Guillaume, Khosa, Celso, Borand, Laurence, Mwanga-Amumpaire, Juliet, Mustapha, Ayeshatu, Nolna, Sylvie Kwedi, Komena, Eric, Mugisha, Jacob Ross, Natukunda, Naome, Dim, Bunnet, de Lauzanne, Agathe, Cumbe, Saniata, Balestre, Eric, Poublan, Julien, Lounnas, Manon, Ngu, Eden, Joshi, Basant, Norval, Pierre-Yves, Terquiem, Etienne Leroy, Turyahabwe, Stavia, Foray, Lynda, Sidibé, Souleymane, Manhiça, Ivan, Sekadde, Moorine, Detjen, Anne, Verkuijl, Sabine, Mao, Tan Eang, Orne-Gliemann, Joanna, Bonnet, Maryline, and Marcy, Olivier
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- 2024
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85. Geometric representability of 1-cycles on rationally connected threefolds
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Voisin, Claire
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Mathematics - Algebraic Geometry - Abstract
We prove that for any rationally connected threefold $X$, there exists a smooth projective surface $S$ and a family of $1$-cycles on $X$ parameterized by $S$, inducing an Abel-Jacobi isomorphism ${\rm Alb}(S)\cong J^3(X)$. This statement was previously known for some classes of smooth Fano threefolds., Comment: Final version, to appear in the Collino memorial volume "Perspectives on four decades: Algebraic Geometry 1980-2020"
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- 2022
86. Multi-colour optical light curves of the companion star to the millisecond pulsar PSR J2051-0827
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Dhillon, V. S., Kennedy, M. R., Breton, R. P., Clark, C. J., Sánchez, D. Mata, Voisin, G., Breedt, E., Brown, A. J., Dyer, M. J., Green, M. J., Kerry, P., Littlefair, S. P., Marsh, T. R., Parsons, S. G., Pelisoli, I., Sahman, D. I., Wild, J. F., van Kerkwijk, M. H., and Stappers, B. W.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present simultaneous, multi-colour optical light curves of the companion star to the black-widow pulsar PSR J2051-0827, obtained approximately 10 years apart using ULTRACAM and HiPERCAM, respectively. The ULTRACAM light curves confirm the previously reported asymmetry in which the leading hemisphere of the companion star appears to be brighter than the trailing hemisphere. The HiPERCAM light curves, however, do not show this asymmetry, demonstrating that whatever mechanism is responsible for it varies on timescales of a decade or less. We fit the symmetrical HiPERCAM light curves with a direct-heating model to derive the system parameters, finding an orbital inclination of $55.9^{+4.8}_{-4.1}$ degrees, in good agreement with radio-eclipse constraints. We find that approximately half of the pulsar's spin-down energy is converted to optical luminosity, resulting in temperatures ranging from approximately $5150^{+190}_{-190}$ K on the day side to $2750^{+130}_{-150}$ K on the night side of the companion star. The companion star is close to filling its Roche lobe ($f_{\rm RL} =0.88^{+0.02}_{-0.02}$) and has a mass of $0.039^{+0.010}_{-0.011}$ M$_{\odot}$, giving a mean density of $20.24^{+0.59}_{-0.44}$ g cm$^{-3}$ and an apsidal motion constant in the range $0.0036 < k_2 < 0.0047$. The companion mass and mean density values are consistent with those of brown dwarfs, but the apsidal motion constant implies a significantly more centrally-condensed internal structure than is typical for such objects., Comment: 10 pages, 4 figures, 3 tables, accepted for publication in Monthly Notices of the Royal Astronomical Society
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- 2022
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87. Quasiparticle excitations in a one-dimensional interacting topological insulator: Application for dopant-based quantum simulation
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Mikhail, David, Voisin, Benoit, Medar, Dominique Didier St, Buchs, Gilles, Rogge, Sven, and Rachel, Stephan
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Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Strongly Correlated Electrons - Abstract
We study the effects of electron-electron interactions on the charge excitation spectrum of the spinful Su-Schrieffer-Heeger (SSH) model, a prototype of a 1D bulk obstructed topological insulator. In view of recent progress in the fabrication of dopant-based quantum simulators we focus on experimentally detectable signatures of interacting topology in finite lattices. To this end we use Lanczos-based exact diagonalization to calculate the single-particle spectral function in real space which generalizes the local density of states to interacting systems. Its spatial and spectral resolution allows for the direct investigation and identification of edge states. By studying the non-interacting limit, we demonstrate that the topological in-gap states on the boundary are robust against both finite-size effects as well as random bond and onsite disorder which suggests the feasibility of simulating the SSH model in engineered dopant arrays in silicon. While edge excitations become zero-energy spin-like for any finite interaction strength, our analysis of the spectral function shows that the single-particle charge excitations are gapped out on the boundary. Despite the loss of topological protection we find that these edge excitations are quasiparticle-like as long as they remain within the bulk gap. Above a critical interaction strength of $U_c\approx 5 t$ these quasiparticles on the boundary loose their coherence which is explained by the merging of edge and bulk states. This is in contrast to the many-body edge excitations which survive the limit of strong coupling, as established in the literature. Our findings show that for moderate repulsive interactions the non-trivial phase of the interacting SSH model can be detected through remnant signatures of topological single-particle states using single-particle local measurement techniques such as scanning tunneling spectroscopy., Comment: 16 pages + 13 figures; v2: final version
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- 2022
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88. Mesoscopic Klein-Schwinger effect in graphene
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Schmitt, A., Vallet, P., Mele, D., Rosticher, M., Taniguchi, T., Watanabe, K., Bocquillon, E., Fève, G., Berroir, J. M., Voisin, C., Cayssol, J., Goerbig, M. O., Troost, J., Baudin, E., and Plaçais, B.
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Condensed Matter - Mesoscale and Nanoscale Physics ,High Energy Physics - Theory - Abstract
Strong electric field annihilation by particle-antiparticle pair creation, also known as the Schwinger effect, is a non-perturbative prediction of quantum electrodynamics. Its experimental demonstration remains elusive, as threshold electric fields are extremely strong and beyond current reach. Here, we propose a mesoscopic variant of the Schwinger effect in graphene, which hosts Dirac fermions with an approximate electron-hole symmetry. Using transport measurements, we report on universal 1d-Schwinger conductance at the pinchoff of ballistic graphene transistors. Strong pinchoff electric fields are concentrated within approximately 1 $\mu$m of the transistor's drain, and induce Schwinger electron-hole pair creation at saturation. This effect precedes a collective instability toward an ohmic Zener regime, which is rejected at twice the pinchoff voltage in long devices. These observations advance our understanding of current saturation limits in ballistic graphene and provide a direction for further quantum electrodynamic experiments in the laboratory., Comment: 39 pages, 13 figures, final version with extended discussion of the pinchoff effect in supplementary informations, abstract updated
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- 2022
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89. Detecting common bubbles in multivariate mixed causal-noncausal models
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Cubadda, Gianluca, Hecq, Alain, and Voisin, Elisa
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Economics - Econometrics - Abstract
This paper proposes methods to investigate whether the bubble patterns observed in individual series are common to various series. We detect the non-linear dynamics using the recent mixed causal and noncausal models. Both a likelihood ratio test and information criteria are investigated, the former having better performances in our Monte Carlo simulations. Implementing our approach on three commodity prices we do not find evidence of commonalities although some series look very similar.
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- 2022
90. The Relationship between Religion, Substance Misuse, and Mental Health among Black Youth.
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Quinn, Camille, Waller, Bernadine, Hughley, Ashura, Boyd, Donte, Cobb, Ryon, Hardy, Kimberly, Radney, Angelise, and Voisin, Dexter
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black youth ,critical theory ,mental health ,religiosity - Abstract
Studies suggest that religion is a protective factor for substance misuse and mental health concerns among Black/African American youth despite reported declines in their religious involvement. However, few studies have investigated the associations among religion, substance misuse, and mental health among Black youth. Informed by Critical Race Theory, we evaluated the correlations between gender, depression, substance misuse, and unprotected sex on mental health. Using multiple linear regression, we assessed self-reported measures of drug use and sex, condom use, belief in God, and religiosity on mental health among a sample of Black youth (N = 638) living in a large midwestern city. Results indicated drug use, and sex while on drugs and alcohol, were significant and positively associated with mental health symptoms. Belief in God was negatively associated with having sex while on drugs and alcohol. The studys findings suggest that despite the many structural inequalities that Black youth face, religion continues to be protective for Black youth against a myriad of prevalent problem behaviors.
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- 2023
91. COVID-19, Retention in HIV Care, and Access to Ancillary Services for Young Black Men Living with HIV in Chicago
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Voisin, Dexter R, Edwards, Travonne, Takahashi, Lois M, Valadez-Tapia, Silvia, Shah, Habiba, Oselett, Carter, Bouacha, Nora, Dakin, Andrea, and Quinn, Katherine
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Public Health ,Health Sciences ,Health Services ,Social Determinants of Health ,Clinical Research ,Infectious Diseases ,HIV/AIDS ,Sexually Transmitted Infections ,Behavioral and Social Science ,Mental Health ,Prevention ,Health Disparities ,Sexual and Gender Minorities (SGM/LGBT*) ,Coronaviruses ,Minority Health ,Pediatric ,Pediatric AIDS ,Emerging Infectious Diseases ,8.1 Organisation and delivery of services ,Good Health and Well Being ,Male ,Humans ,Homosexuality ,Male ,HIV Infections ,Chicago ,Sexual and Gender Minorities ,COVID-19 ,HIV care continuum ,Medical care improvements ,YBMSM ,Public Health and Health Services ,Social Work ,Public health - Abstract
This study conducted 28 semi-structured, in-depth interviews with Young Black Men who have Sex with Men in Chicago to investigate the impact of COVID-19 on their HIV care and ancillary service access. The qualitative analysis identified both negative and positive effects. The negative effects included: (l) mixed disruptions in linkage to and receipt of HIV care and ancillary services, and (2) heightened concerns about police and racial tensions in Chicago following the murder of George Floyd, contributing to possible disruption of retention in care. The positive effects included: (1) the ability to reflect and socially connect, contributing to heightened self-care and retention in care, and (2) some improvements in receipt of medical care. These findings suggest that while COVID-19 disruptions in care reduced in-person use of HIV care, the expansion of telemedicine allowed more administrative tasks to be handled online and focused in-person interactions on more substantive interactions.
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- 2023
92. Correction to: Ecological aspects and relationships of the emblematic Vachellia spp. exposed to anthropic pressures and parasitism in natural hyper-arid ecosystems: ethnobotanical elements, morphology, and biological nitrogen fixation
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Vincent, Bryan, Bourillon, Julie, Gotty, Karine, Boukcim, Hassan, Selosse, Marc-André, Cambou, Aurélie, Damasio, Coraline, Voisin, Mathis, Boivin, Stéphane, Figura, Tomas, Nespoulous, Jérôme, Galiana, Antoine, Maurice, Kenji, and Ducousso, Marc
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- 2024
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93. Ecological aspects and relationships of the emblematic Vachellia spp. exposed to anthropic pressures and parasitism in natural hyper-arid ecosystems: ethnobotanical elements, morphology, and biological nitrogen fixation
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Vincent, Bryan, Bourillon, Julie, Gotty, Karine, Boukcim, Hassan, Selosse, Marc-André, Cambou, Aurélie, Damasio, Coraline, Voisin, Mathis, Boivin, Stéphane, Figura, Tomas, Nespoulous, Jérôme, Galiana, Antoine, Maurice, Kenji, and Ducousso, Marc
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- 2024
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94. Metabologenomic characterization uncovers a clinically aggressive IDH mutant glioma subtype
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Nassiri, Farshad, Ajisebutu, Andrew, Patil, Vikas, Mamatjan, Yasin, Liu, Jeff, Wang, Justin Z., Voisin, Mathew R., Nejad, Romina, Mansouri, Sheila, Karimi, Shirin, Chakravarthy, Ankur, Chen, Eric, De Carvalho, Daniel D., Aldape, Kenneth, and Zadeh, Gelareh
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- 2024
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95. Les derniers jours des reines
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Voisin, Jean-Louis, primary
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- 2024
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96. Mobile air-decontamination units: Can they be used for immunocompromised patients at high risk for fungal infections?
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Joris Voisin, Jacqueline Shum Cheong Sing, Claire Terreaux-Masson, Carola Pierobon, Anne Thiebaut-Bertrand, Hervé Pelloux, Caroline Landelle, and Marie-Pierre Brenier-Pinchart
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Invasive aspergillosis ,Molds ,Environmental fungal risk ,Air ,Mobile air-decontamination unit ,Public aspects of medicine ,RA1-1270 ,Environmental sciences ,GE1-350 - Abstract
Immunocompromised patients in the hematology department are usually hospitalized in areas protected by the high-efficiency particulate air (HEPA) filtration system. Renovations may require moving these patients at risk for invasive fungal infection to areas without HEPA. Mobile air handling units may be a solution in these cases. For renovation purposes, we evaluated the efficiency of mobile air handling units called Plasmair® as well as their optimization, by comparing two generations of devices.Particle counts were performed to determine a particle cleanliness classification according to the ISO 14644–1 standard (high ISO classes correspond to a degraded particulate cleanliness). Mycological air samples were also taken to determine the percentage of positive samples and the median number of filamentous fungi colonies.Without air treatment, only 18 % (38/216) of particle counts were classified as ISO 6. With the use of mobile air treatment units, this proportion increased to 71 % (205/288). The positivity rate of mycological samples without air treatment was 86 % (31/36) with a median number of fungal colonies of 3 (1–5)/0.5m3. A significant decrease in fungal pressure was observed when using Plasmair®. Percentages of positive air samples and the median number of colonies found between the old generation Plasmair® (T2006) and the new generation Plasmair® (Guardian) were significantly different, respectively 55.6 % (20/36) versus 22.2 % (8/36) and 1(0–1) versus 0 (0–0).Finally, we confirm Plasmair® were effective in reducing airborne fungal pressure, the new generation especially. However, they were not effective enough to obtain negative mycological air samples as usually observed with the HEPA system, whatever the generation.
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- 2024
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97. Syngeneic mouse model of YES-driven metastatic and proliferative hepatocellular carcinoma
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Laure Voisin, Marjorie Lapouge, Marc K. Saba-El-Leil, Melania Gombos, Joaquim Javary, Vincent Q. Trinh, and Sylvain Meloche
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hepatocellular carcinoma ,tyrosine kinase ,src family kinases ,cancer mouse model ,Medicine ,Pathology ,RB1-214 - Published
- 2024
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98. Modelling and application of joint maintenance grouping and workload smoothing for an automotive plant.
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Minh-Tuan Truong, Hai Canh Vu, Phuc Do, Benoît Iung, and Alexandre Voisin
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- 2024
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99. Topological Simplification of Signals for Inference and Approximate Reconstruction
- Author
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Koplik, Gary, Borggren, Nathan, Voisin, Sam, Angeloro, Gabrielle, Hineman, Jay, Johnson, Tessa, and Bendich, Paul
- Subjects
Electrical Engineering and Systems Science - Signal Processing ,Computer Science - Information Theory ,Computer Science - Machine Learning - Abstract
As Internet of Things (IoT) devices become both cheaper and more powerful, researchers are increasingly finding solutions to their scientific curiosities both financially and computationally feasible. When operating with restricted power or communications budgets, however, devices can only send highly-compressed data. Such circumstances are common for devices placed away from electric grids that can only communicate via satellite, a situation particularly plausible for environmental sensor networks. These restrictions can be further complicated by potential variability in the communications budget, for example a solar-powered device needing to expend less energy when transmitting data on a cloudy day. We propose a novel, topology-based, lossy compression method well-equipped for these restrictive yet variable circumstances. This technique, Topological Signal Compression, allows sending compressed signals that utilize the entirety of a variable communications budget. To demonstrate our algorithm's capabilities, we perform entropy calculations as well as a classification exercise on increasingly topologically simplified signals from the Free-Spoken Digit Dataset and explore the stability of the resulting performance against common baselines., Comment: 10 pages, 12 figures
- Published
- 2022
100. One pulsar, two white dwarfs, and a planet confirming the strong equivalence principle
- Author
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Voisin, Guillaume, Luth, G, Cognard, I, Freire, P, Wex, N, Guillemot, L, Desvignes, G, Kramer, M, Theureau, G, and Saillenfest, M
- Subjects
Astrophysics - High Energy Astrophysical Phenomena ,General Relativity and Quantum Cosmology - Abstract
The strong equivalence principle is a cornerstone of general relativity, tested with exquisite accuracy in the Solar system. However, tests in the strong-field regime require a compact object. Currently, PSR J0337+1715 is the unique millisecond pulsar found in a triple stellar system, orbiting two white dwarfs within an area comparable to the orbit of the Earth. This configuration offers the opportunity for a dramatic improvement over previous tests, provided that accurate and regular timing of the pulsar can be achieved. This also requires the development of a new timing model solving numerically the relativistic three-body problem with great accuracy. We report on the analysis of the high-quality dataset gathered on PSR J0337+1715 by the Nan{\c c}ay radiotelescope over the past 8 years. In particular, I will show how we could obtain the most stringent limit to-date on a potential violation of the strong equivalent principle in the strong field regime. I will also introduce preliminary resuts showing that the presence of a small planet in the system may explain a tiny residual signal so far unaccounted for, which if confirmed would make this system exceptionally rich., Comment: On behalf of: I. Cognard, P.C.C. Freire, N. Wex, L. Guillemot, G. Desvignes, M. Kramer, G. Theureau, M. Saillenfest
- Published
- 2022
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