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Copyright of Engineering Management & Technology Discussion is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Management & Technology Discussion is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Homestead reconstruction is one of the most effective means to govern rural planning. Traditional research cannot fully consider the individual differences of rural homesteads, easily leading to uneven spatial development, and even social and economic problems. In this study, a novel framework of rural settlement was reconstructed to integrate the land suitability and reconstruction urgency of rural homesteads. The individual differences were considered in the rural homesteads using a questionnaire survey in Pingba Village, Chongqing City, in southwest China. This framework combined the differentiated characteristics of rural homesteads, in terms of the concentration ratio, utilization status, livelihood, travel convenience, and willingness to relocate. A comprehensive evaluation index was established to divide the rural homesteads into different reconstruction types. Participatory rural assessment (PRA) was selected to conduct the questionnaire survey in all 292 peasant households living in the study area. The results show that: 1) more than half of the rural settlements were distributed in the highsuitability areas before reconstruction. A trend of agglomeration was found under the complex terrain and location conditions in the mountainous areas. 2) The scale of rural homesteads were expanded three times that need to be optimized in the study area after considering individual differences, compared with only land suitability. The newly added rural homesteads shared the land suitability, but there was low utilization or a conflict between the expected production output and lifestyle. 143 rural homesteads were then determined to be optimized using reconstruction, according to their own utilization problems. The obstacles of these homesteads were identified, in terms of the utilization status, travel convenience, and concentration ratio. 3) The land suitability and individual needs were comprehensively considered to divide into five types: the retained, locally rebuilt, integrated, production-, and travel-based relocated homestead. The proportions of the five types of homesteads were 34.79%, 22.89%, 9.04%, 16.94%, and 16.34%, respectively. Furthermore, the types were varied in the different reconstruction needs. Among them, the retained homesteads were the fundamental reconstruction. Production- and travel-based relocated homesteads needed to be optimized and reconstructed after relocation. 4) The five types of homesteads constituted of three optimization modes: relocation, integration, and space replacement. The new spatial pattern of rural settlements was established after rebuilding, relocating, and replacing the five types. Finally, 10.34 hm² of construction land resources were saved after optimization, which was far greater than the amount of the conserved when considering only the land suitability. The integration and replacement modes were added to produce the more complex reconstruction of rural homesteads within the village, compared with the simple demolition and relocation. The rural homesteads were shifted from areas of low or no suitability into high ones, indicating the increasing number. Therefore, the larger scale of rural homesteads in the regions with the higher suitability was conducive to the realization of a new pattern with the moderately centralized residency in the mountainous villages. The reconstruction significantly improved the level of agricultural suitability in the rural homesteads, fully meeting the differentiated needs of farmers for utilization. The finding can provide a new perspective on rural planning and space governance. An exploratory tool can be expected for rural space optimization, considering the influence of individual differences in the rural homesteads on the rural reconstruction plans. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Henan Agricultural Sciences is the property of Editorial Board of Journal of Henan Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

黏蛋白 5AC（MUC5AC）和黏蛋白 5B（MUC5B）是肺部气道黏液中最主要的凝胶形成黏蛋白，参与许多肺 部疾病的发生发展。黏液阻塞性肺疾病主要有慢性阻塞性肺病（COPD）、哮喘及囊性纤维化（CF）等，MUC5B可通过 干扰信号转导和转录激活因子 6-上皮特异性 ETS 转录因子通路表达，改变气道黏蛋白成分，参与 COPD 的发生发 展；MUC5AC及MUC5B表达变化参与哮喘的炎症反应；MUC5AC及MUC5B表达增加，可促进呼吸道黏蛋白的分泌， 使其形成黏液栓，参与CF的发生发展。MUC5B过表达可导致黏液纤毛功能障碍、促进蜂窝囊肿形成，促进特发性 肺纤维化（IPF）的发生发展；MUC5B基因rs35705950位点多态性可能与IPF的易感性有关；MUC5AC通过调控黏膜 损伤后上皮伤口愈合、细胞应激、黏膜损伤和修复途径激活，参与 IPF 的气道上皮失衡。此外，表达异常的 MUC5AC、MUC5B可使气道黏液产生异常、黏液生理特性改变，导致新型冠状病毒肺炎患者的气道症状持续存在。 [ABSTRACT FROM AUTHOR]

Copyright of Engineering Mechanics / Gongcheng Lixue is the property of Engineering Mechanics Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Plateau Meteorology is the property of Plateau Meteorology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Ecology & Rural Environment is the property of Journal of Ecology & Rural Environment Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Applied Ecology / Yingyong Shengtai Xuebao is the property of Chinese Journal of Applied Ecology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Mechanics / Gongcheng Lixue is the property of Engineering Mechanics Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agriculturae Zhejiangensis is the property of Acta Agriculturae Zhejiangensis Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Architecture & Civil Engineering is the property of Chang'an Daxue Zazhishe and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Railway Science & Engineering is the property of Journal of Railway Science & Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Ordnance Equipment Engineering is the property of Chongqing University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

牙本质敏感症是一种临床常见的口腔疾病, 该疾病是由于牙釉质被破坏造成牙本质暴露于外界环境, 在外界环境刺激下产生疼痛不适。堵塞牙本质小管已成为治疗牙本质敏感症的最直接方式。生物活性材料是一种能在材料界面引发特定的生物反应, 从而使组织与材料之间形成结合的物质, 其在促进骨组织与软组织的修复再生领域得到广泛应用。生物活性玻璃、介孔二氧化硅纳米颗粒 (MSNs)、羟基磷灰石生物材料、非胶原蛋白模拟物、聚酰胺-胺（PAMAM）树枝状分子和儿茶酚基聚合物等生物活性材料均能诱导牙本质再矿化或仿生矿化, 在牙本质敏感症的治疗中具有重要作用。目前, 国内外学者对于生物活性玻璃在多种口腔疾病中的研究和应用报道较多, 而其他生物活性材料的研究较少, 且多局限于基础实验研究阶段。现结合国内外相关最新研究成果, 将生物活性材料分为无机非金属材料与有机材料两大类, 对其自身特性以及促进牙本质再矿化或仿生矿化的作用机制进行简要综述, 旨在为其在牙本质敏感症治疗方面的应用提供参考。 [ABSTRACT FROM AUTHOR]

Copyright of Control Theory & Applications / Kongzhi Lilun Yu Yinyong is the property of Editorial Department of Control Theory & Applications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Architecture & Civil Engineering is the property of Chang'an Daxue Zazhishe and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of School Administrators is the property of School Administration Research Association, R.O.C. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Precious Metals / Guijinshu is the property of Precious Metals Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Management & Technology Discussion is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Science Research & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objectives Based on the information from the random inspection of foods by the China Food and Drug Administration in 2022, the contamination levels of lead ions are high in many edible products. Traditional methods of detecting lead ions cannot meet the requirements of on-site analysis of food due to the need for large equipment. The immunochromatographic assay (ICA) is an effective, rapid, on-site analytical technique for determining lead ions in foods. However, the performance of ICA based on the traditional probe (AuNP-mAb) is limited by ignoring the influence of the antibody orientation. Materials and Methods In this study, we developed an efficient technology for constructing a universal probe (AuNP-PrA-mAb) based on the oriented immobilization of antibody. The performance of ICA was largely improved due to specific binding of the Fc region of the antibody with recombinant protein A (PrA) on the surface of a gold nanoparticle (AuNP). The ICA based on a universal probe was applied for the qualitative and quantitative detection of lead ions in Procambarus clarkii within 30 min. Meanwhile, a simple and fast pretreatment method based on dilute acid extraction was developed for pretreating the P. clarkii containing lead ions. Results The visual limit of detection and the scanning limit of quantization of the developed ICA strip for lead ions were 0.5 ng/mL and 0.28 ng/mL, respectively. The sensitivity of ICA based on universal probe was 10-fold higher than that of the ICA using traditional probe. Furthermore, the detection results had no obvious difference between the ICA and ICP-MS with t -test statistical method. Conclusions The developed ICA based on a universal probe presented broad application prospects in detecting contaminants in foods. [ABSTRACT FROM AUTHOR]

In this paper, the effect of different concentrations of sucrose stress on color formation of the Staphylococcus xylosus was investigated. The results showed that the highest a * value and the best coloring effect similar to those of nitrite were observed after the addition of 0.05 g/mL sucrose to stress the S. xylosus. UV-Vis and electron spin resonance spectra analysis showed that production of coloring product Mb-NO was significantly enhanced after 0.05 g/mL sucrose stress. The growth curve, reactive oxygen content, cell cycle, nitric oxide synthase (NOS) activity, zeta potential, cell size, and protein composition of S. xylosus were investigated to reveal the mechanism of sucrose stress to enhance the coloring effect of the strain. The result showed that sucrose inhibited the growth of S. xylosus , which changed the physiological state by activating the oxidative stress response. The stress altered the rate of intracellular metabolism of S. xylosus by delaying the cell cycle and increasing cell surface zeta potential and cell particle size. These changes altered the protein composition of the cells and significantly enhanced the activity of intracellular NOS, which could improve the chromogenic ability of S. xylosus. This study will provide theoretical support for sucrose stress on S. xylosus to enhance its coloring effect, and sucrose stress for S. xylosus might be a promising biological alternative to nitrite in meat products. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The preparation of high concentration ozonated water（≥100 mg/L） using insoluble gas ozone has been an international technical challenge.A high concentration ozonated water preparation system was assembled using a commercial ozone gas generator optimized and modified, and a dissolved gas device designed according to the double membrane dissolved gas theory and the principle of hydrostatic equilibrium.The ozonated water concentration increases with the increase of power, and the decrease of water temperature can improve the ozone solubility and ozonated water concentration.The effective gas dissolution efficiency can reach more than 90% when the power of ozone generator did not exceed 900 W.With the increase of gas-liquid ratio, the ozone gas dissolution efficiency raised and then decreased, and the best gas-liquid ratio was about 1.5.Under the test conditions of tap water, the pressure of 0.2 MPa, the water flow rate of 60 L/h, the gas-to-liquid ratio of 1.5 and the full power of 1 000 W,the ozonated water concentration exceeded 200 mg/L and appeared blue at the water temperature of 8.9 ℃.Moreover the ozonated water concentration was 149.4 mg/L at the water temperature of 22.4 ℃.This work is a breakthrough in the field of high concentration ozonated water preparation technology. [ABSTRACT FROM AUTHOR]

Copyright of Engineering Mechanics / Gongcheng Lixue is the property of Engineering Mechanics Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Application Research of Computers / Jisuanji Yingyong Yanjiu is the property of Application Research of Computers Edition and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Railway Science & Engineering is the property of Journal of Railway Science & Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Oil Crop Sciences is the property of Oil Crops Research Institute of Chinese Academy of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agricultural Resources & Environment / Nongye Ziyuan yu Huanjing Xuebao is the property of Journal of Agricultural Resources & Environment Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electric Machines & Control / Dianji Yu Kongzhi Xuebao is the property of Electric Machines & Control and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 总结老年气管支气管结核 (TBTB) 的临床特点。方法 对 121 例老年 TBTB 患者的临床资料作回 顾性分析。结果 121 例老年 TBTB 患者均经支气管镜活检确诊, 合并肺结核、淋巴结核、结核性胸膜炎120例, 有基 础性疾病者 73 例。临床表现以呼吸道症状为主, 包括咳嗽、咳痰、发热、胸闷和胸痛等, 也有乏力、盗汗等全身症状。 胸部CT检查提示感染性病变110例、支气管管腔狭窄48例、合并肺空洞18例。114例接受痰涂片抗酸染色检查, 阳 性 70 例; 92 例接受痰结核分枝杆菌培养检查, 阳性80例; 60例行痰PCR检测, 阳性51例; 66例行肺泡灌洗液涂片抗 酸染色, 阳性41例; 60 例行肺泡灌洗液结核分枝杆菌培养, 阳性53例; 82例行气管镜刷片抗酸染色, 阳性55例。病 变位于主气道及隆突 12 例, 左主、叶、段支气管病变59例, 右主、叶、段支气管病变100例。疾病分型为溃疡坏死型 52例、肉芽增殖型32例、炎症浸润型26 例、瘢痕狭窄型9例、管壁软化型2例, 未发现淋巴结瘘型。病理学表现为仅 见坏死型56例、典型结核结节 42 例、仅见肉芽肿19例、仅见朗罕氏巨细胞或上皮样细胞4例。结论 老年TBTB临 床表现以咳嗽、咳痰多见, 影像学主要表现为感染性改变、支气管管腔狭窄, 分子生物学、结核分枝杆菌培养等病原 学检查阳性率均较高, 病变多侵犯右侧支气管, 分型以溃疡坏死型、肉芽增殖型及炎症浸润型多见, 病理形态改变主 要为坏死和典型结核结节。 [ABSTRACT FROM AUTHOR]

Regional Production-Living-Ecological Space (PLES) has been one of the most important indicators in territorial space planning. Spatial-temporal evolution and development trends can be greatly contributed to the orderly utilization, renovation, and restoration of regional territorial space in the future. In this study, a transfer matrix and dynamic attitude model was proposed to analyze the dynamic evolution characteristics of the scale, structure, and pattern of PLES from 1990 to 2020. A Future Land Use Simulation (FLUS) model was then used to simulate the land spatial pattern of Shizhu County, Chongqing City, China in 2035. Three scenarios were performed on natural development, cultivated land protection, and ecological protection. The results showed that: 1) The ecological space was the main area, followed by the production space, and the living space with the least proportion. In general, the production space was the main area in the west, whereas, the ecological space was in the east. The PLES was also dominated by the green ecological, and agricultural production space, accounting for over 65% and 30%, respectively. As such, diversified geographical characteristics were created in this case. Among them, the green ecological space was distributed in the Fangdu Mountain Range and the Qiyao Mountain Range, leading to two natural ecological space barriers running diagonally across the whole territory. Agricultural production space was mainly distributed in the trough and valley between the two mountain ranges and along the Yangtze River in the western part of the county. 2) The production space decreased slightly during the study period. By contrast, there were slight and significant increases in the ecological and living space, respectively. The transfer of PLES showed the spatial characteristics of “overall dispersion and local concentration”. The expansion of industrial production space was mainly distributed in Xituo Town along the Yangtze River and Xilu Street in the study area. In addition, the urban area was located, while other townships were scattered. The expansion of urban living space was mainly distributed in Wanan and Nanbin Street, where the urban area was located, while other new spaces were scattered throughout the county. 3) There were significant changes in the PLES under the three scenarios. Specifically, the agricultural production space was transferred into other spaces under the natural development scenario. A good balance was also gained in the area of transferring. By contrast, there were different degrees of expansion in other spaces. A significant shrinkage trend was found in the green ecological space. Moreover, the transfer out of agricultural production space was strictly controlled under the scenario of arable land protection. As such, the arable land was effectively protected during this time. However, the green ecological space was the largest transfer out space. Furthermore, the ecological space pattern was effectively protected with the increased area under the ecological protection scenario. But, the agricultural production space shrunk significantly, while the area of all other types of space increased. These results were better correspondent with the socio-economic development trend and regional development pattern in the study area. The finding can provide theoretical support for territorial space management and optimization. A recommendation was made on the national spatial control to improve the level of intensive use of living space, for the better protection of agricultural production space, as well as the protection and restoration of ecological space in the future. [ABSTRACT FROM AUTHOR]

Copyright of Forest Research is the property of Forest Research Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Food Science & Technology is the property of Editorial Office of Modern Food Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Tornado is a destructive natural phenomenon. With the fast development of high speed train technology， the scientific risk evaluation of the tornado affection on high speed train becomes necessary. Therefore，this paper proposes a new method to analyze the overturning probability of high‐speed train under the influence of tornado. In this method，the existing meteorological data were statistically sorted out，and Monte Carlo simulation was adopted. Weibull distribution was used to simulate the intensity and length of tornadoes，and the uniform distribution was used to simulate the location，direction and time of tornado. By combining the simulated tornado with the schedule of high‐speed railway，the relative position relationship between the two is obtained，so as to analyze the wind load and judge the overturning of the train. This article uses a Japanese case to illustrate in detail. Based on Japan’s 55‐year tornado data and Tokaido Line train information，the simulations get that the probability of train overturning and crossing the railway within 50，000 years is 8.1×10-5 and 5.3×10-3，respectively. It is also found that the overturning probability and the number of trains per unit time are linearly positive at different speeds，and the greater the speed，the greater the slope of fitted curve；when the number of trains remains unchanged，the overturning risk can be reduced by 19% by adjusting the train departure interval. [ABSTRACT FROM AUTHOR]