751. Uveitis: an emerging clinical form of Bartonella infection
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Didier Raoult, Michel Drancourt, Céline Terrada, Bahram Bodaghi, and J. Conrath
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Adult ,DNA, Bacterial ,Male ,Microbiology (medical) ,Bartonella ,medicine.medical_specialty ,Pathology ,Adolescent ,Uveitis ,Young Adult ,Bartonella Infections ,Surveys and Questionnaires ,Prevalence ,medicine ,Humans ,Prospective Studies ,Child ,Aged ,Aged, 80 and over ,Bartonella henselae ,biology ,business.industry ,Cat-scratch disease ,General Medicine ,Middle Aged ,biology.organism_classification ,medicine.disease ,Antibodies, Bacterial ,Dermatology ,Toxoplasmosis ,Bartonella grahamii ,Infectious Diseases ,Child, Preschool ,Bartonella quintana ,Female ,France ,business ,Bartonella Infection - Abstract
A few reports have now established that the cat scratch disease agent Bartonella henselae is responsible for uveitis [1]. Bartonella grahamii has also been recognized as being responsible for uveitis [2]. However, the prevalence of Bartonella uveitis remains poorly known, as is the potential role of other Bartonella species. Prospective evaluation of a standardized laboratory protocol for the diagnosis of uveitis of unknown aetiology [3] showed that Bartonella species were responsible for most cases of bacterial uveitis. Prominent clinical features and laboratory diagnosis data of this large series are reported herein. This study was approved by the Ethics Committee of our institution; patients with a known aetiological diagnosis and patients with ophthalmological features pathognomonic of an aetiology, such as toxoplasmosis, were not eligible. A questionnaire was used for the collection of data, and was anonymized before the study according to French law. Informed consent for inclusion was obtained from patients and parents or legal guardians of children (i.e. age
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