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752. Transplantaton antigens.

Author

Kahan BD and Reisfeld RA

Subjects
Amino Acid Sequence, Animals, Cell Membrane immunology, Chromatography, Ion Exchange, Electrophoresis, Disc, Histocompatibility, Humans, Hypersensitivity, Delayed, Liver immunology, Lymphoid Tissue immunology, Molecular Biology, Peptides, Skin Transplantation, Solubility, Spleen immunology, Surface Properties, Surface-Active Agents, Transplantation, Heterologous, Ultracentrifugation, Ultrasonics, Antigens, Transplantation Immunology
Published
1969
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753. Salt extraction of soluble HL-A antigens.

Author

Reisfeld RA, Pellegrino MA, and Kahan BD

Subjects
Culture Techniques, Electrophoresis, Histocompatibility Testing, Hypertonic Solutions, Lymphocytes immunology, Methods, Potassium Chloride, Ultracentrifugation, Antigens isolation & purification, Histocompatibility, Solubility
Abstract

Extraction of cultured human lymphoid cells with hypertonic salt solutions (3 molar potassium chloride) resulted in high recoveries of membrane-associated histocompatibility (HL-A) antigens in soluble form with potent activity and marked immunologic specificity. The active principle was purified by preparative acrylamide-gel electrophoresis. Application of the hypertonic salt extraction method is now yielding sufficient HL-A antigen to begin the elucidation of the molecular basis of transplantation individuality.

Published
1971
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754. Advances in the chemistry of transplantation antigens.

Author

Kahan BD and Reisfeld RA

Subjects
Amino Acid Sequence, Animals, Chromatography, Gel, Electrophoresis, Disc, Epitopes, Genetic Code, Guinea Pigs, Humans, Immunochemistry, Iodine Isotopes, Proteins analysis, Skin Transplantation, Species Specificity, Spleen immunology, Transplantation, Homologous, Ultracentrifugation, Vibration, Histocompatibility, Isoantigens analysis, Isoantigens isolation & purification, Transplantation Immunology
Published
1969

755. Markers of biological individuality.

Author

Reisfeld RA and Kahan BD

Subjects
Animals, Antigens, Genetic Code, Graft Rejection, Histocompatibility, Humans, Immunogenetics, Mice, Neoplasm Transplantation, Rabbits, Skin Transplantation, Species Specificity, Spleen immunology, Transplantation, Homologous, Molecular Biology, Transplantation Immunology
Published
1972
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756. An in vitro approach to transplant rejection.

Author

Kahan BD, Tom BH, Mittal KK, and Bergan JJ

Subjects
Graft Rejection immunology, HLA Antigens, Humans, In Vitro Techniques, Lymphocytes immunology, Time Factors, Transplantation, Homologous, Graft Rejection diagnosis, Kidney Transplantation, Leukocytes immunology
Published
1973

757. Chemical and molecular nature of HL-A antigens.

Author

Reisfeld RA, Pellegrino MA, Ferrone S, and Kahan BD

Subjects
Antibody Formation, Antibody Specificity, Carbon Isotopes, Cells, Cultured, Chromatography, Thin Layer, Electrophoresis, Disc, Epitopes, Humans, Lymphocytes immunology, Molecular Weight, Peptides analysis, Potassium Chloride pharmacology, Solubility, Ultracentrifugation, Histocompatibility Antigens analysis
Published
1973

759. Chemical markers of transplantation individuality solubilized with sonic energy.

Author

Kahan BD and Reisfeld RA

Subjects
Acrylates, Amino Acids analysis, Animals, Antibody Formation, Antigen-Antibody Complex, Binding Sites, Cell Membrane, Cricetinae, Dogs, Electrophoresis, Gels, Genes, Genetics, Graft Rejection, Guinea Pigs, Haplorhini, Histocompatibility, Humans, Hypersensitivity, Delayed, Immunity, Cellular, Mice, Proteins analysis, Rats, Solubility, Transplantation, Homologous, Ultracentrifugation, Vibration, Antigens analysis, Antigens isolation & purification, Transplantation Immunology
Published
1971
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760. Growth rates of mixed leukocyte cultures.

Author

Alling DW and Kahan BD

Subjects
Culture Techniques, Histocompatibility Testing, Humans, Iodine Isotopes, Leukocytes cytology, Models, Biological, Phenotype, Statistics as Topic, Thymidine metabolism, Time Factors, Transplantation, Homologous, Leukocytes immunology, Transplantation Immunology
Published
1969
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761. Water soluble guinea pig transplantation antigen from carcinogen-induced sarcomas.

Author

Kahan BD, Holmes EC, Reisfeld RA, and Morton DL

Subjects
Animals, Benz(a)Anthracenes, Electrophoresis, Femoral Neoplasms, Fibrosarcoma immunology, Guinea Pigs, Hypersensitivity, Delayed, Iodine Isotopes, Liposarcoma immunology, Sarcoma, Experimental immunology, Skin Manifestations, Skin Tests, Solubility, Antigens, Transplantation Immunology
Published
1969

762. The antigenic stimulus in human transplantation.

Author

Kahan BD, Mittal KK, Reisfeld RA, Terasaki PI, and Bergan JJ

Subjects
Antibody Formation, Antigens, Viral, Cytotoxicity Tests, Immunologic, Graft vs Host Reaction, Humans, Hypersensitivity, Delayed, Immune Sera, Isoantibodies, Kidney Transplantation, Lymphocyte Activation, Male, Middle Aged, Nephrectomy, Skin Tests, Solubility, Transplantation, Heterologous, Graft Rejection, Histocompatibility Antigens, Transplantation Immunology
Published
1973

763. Extraction and purification of soluble histocompatibility antigens.

Author

Reisfeld RA and Kahan BD

Subjects
Amino Acids analysis, Animals, Antibody Formation, Antibody-Producing Cells, Cell Line, Cell Membrane immunology, Chromatography, Chromatography, Ion Exchange, Cytotoxicity Tests, Immunologic, Detergents pharmacology, Electrophoresis, Disc, Epitopes, Graft Rejection, Guinea Pigs, Hypersensitivity, Delayed immunology, Immunochemistry, Iodine Isotopes, Isoantigens analysis, Lymphocyte Activation, Mice, Solvents pharmacology, Transplantation Immunology, Ultracentrifugation, Vibration, Histocompatibility, Isoantigens isolation & purification, Solubility
Published
1971
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765. Solubilization of fetal HL-A antigens. A preliminary report.

Author

Pellegrino MA, Pellegrino A, and Kahan BD

Subjects
Antigen-Antibody Reactions, Epitopes, Gestational Age, Humans, Kidney immunology, Liver immunology, Lung immunology, Phenotype, Solubility, Spleen immunology, Tissue Extracts analysis, Vibration, Antigens analysis, Fetus immunology, Immunogenetics, Transplantation Immunology
Published
1970
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767. Quantitative serologic parameters of purified HL-A antigens.

Author

Kahan BD, Pellegrino MA, Papermaster BW, and Reisfeld RA

Subjects
Animals, Antigen-Antibody Reactions, Cross Reactions, Cytotoxicity Tests, Immunologic, Electrophoresis, Epitopes, Guinea Pigs, Humans, Immune Sera, Immunity, Cellular, Immunoassay, Immunodiffusion, In Vitro Techniques, Methods, Mice, Phenotype, Rats, Solubility, Transplantation Immunology, Vibration, Antigens, Histocompatibility, Lymphocytes immunology
Published
1971

770. ISOLATION OF A SOLUBLE TRANSPLANTATION ANTIGEN.

Author

KAHAN BD

Subjects
Animals, Mice, Antigens, Chemical Precipitation, Chemistry Techniques, Analytical, Chromatography, Histocompatibility Antigens, Immunization, Research, Skin Transplantation, Transplantation Immunology, Transplantation, Homologous, Ultracentrifugation
Published
1965
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772. Water-soluble human transplantation antigen.

Author

Kahan BD, Reisfeld RA, Pellegrino MA, Curtoni ES, Mattiuz PL, and Ceppellini R

Subjects
Adult, Aged, Child, Preschool, Chromatography, Gel, Female, Humans, Male, Skin Tests, Solubility, Sound, Water, Antigens analysis, Spleen immunology, Transplantation Immunology
Published
1968
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