501. [Multiple post-chemotherapy plantar nevi].
- Author
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Hueso L, Requena C, Serra-Guillén C, Alfaro A, Nagore E, Llombart B, Botella-Estrada R, Sanmartín O, and Guillén C
- Subjects
- Child, Female, Foot Diseases pathology, Humans, Nevus, Pigmented pathology, Precursor Cell Lymphoblastic Leukemia-Lymphoma drug therapy, Skin Neoplasms pathology, Antineoplastic Agents adverse effects, Foot Diseases chemically induced, Nevus, Pigmented chemically induced, Skin Neoplasms chemically induced
- Abstract
The induction of multiple melanocytic nevi in children after chemotherapy has been documented in the literature. This situation apparently has more to do with the state of immunosuppression that is produced than with any specific agent used. We present the case of a 12-year-old girl who presented with multiple plantar melanocytic nevi after multidrug chemotherapy for acute lymphocytic leukemia. None of the lesions showed any alarming clinical signs. Although the degeneration of post-chemotherapy melanocytic nevi to melanoma has not been documented in any of the cases described, the presence of a high number of melanocytic nevi is an accepted risk factor for melanoma; thus, close clinical follow-up of these patients seems advisable.
- Published
- 2006
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