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The leakage current path in the vertical-type metal–semiconductor–metal structured device fabricated on a Fe-doped bulk GaN substrate with a V-shaped pit is investigated. Micro-Raman, micro-photoluminescence, and atomic force microscope show nonuniform distributions of the optical and electrical properties in the V-shaped pit. The distribution of carrier concentration is determined by the distributions of Si, O, and Fe impurities, which are further influenced by the incorporation efficiency of the corresponding impurities in the semi-polar growth facets. The mechanism of current leakage in a V-shaped pit is explained by the big difference between the resistance inside and outside the pit. [ABSTRACT FROM AUTHOR]

Objective: To explore the features and risk factors of bacterial skin infections (BSIs) in hospitalized patients with bullous pemphigoid (BP)., Methods: Records were retrospectively reviewed for 110 hospitalized patients with BP admitted to Peking University First Hospital between 2013 and 2019. Bacterial species and drug resistance were assessed, and then the underlying risk factors for BSIs were evaluated., Results: Infections were present in 40% (44/110) of the patients. Staphylococcus aureus (72.7%, 32/44) was the most common bacterium, and it was highly resistant to penicillin (81.3%, 26/32), erythromycin (62.5%, 20/32), and clindamycin (56.3%, 18/32), but 100.0% sensitive to vancomycin and tigecycline. Coronary heart disease (P = .02; odds ratio [OR], 12.68), multisystem comorbidities (P = .02; OR, 3.67), hypoalbuminemia (P = .04; OR, 3.70), high levels of anti-BP180 antibodies (>112.4 U/mL; P = .003; OR, 6.43), and season (spring: reference; summer: P = .002; OR, 23.58; autumn: P = .02; OR, 12.19; winter: P = .02; OR, 13.19) were significantly associated with BSIs., Conclusions: Hospitalized patients with BP had a high incidence of BSIs, and those patients with underlying risk factors require careful management to prevent and control BSIs., (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)

Objective: To objectively evaluate the therapeutic effect and safety of Mixture for Nourishing Kidney and Strengthening Bone., Method: Among 160 cases of osteoporosis under clinical observation, 96 patients in the treatment group were treated with Mixture for Nourishing Kidney and Strengthening Bone, 32 patients in the control group were given Shen Gu Capsule and 32 patients in the blank group were given no drug in half a year. Observation and determination were conducted on bone mineral density (BMD), clinical symptoms, bone gla protein (BGP), pyridinoline (PYD), estradiol (E2), testosterone (T), blood urea nitrogen (BUN), transaminase and routine test on blood and urine., Result: The comprehensive effect in the treatment group was remarkably superior to that in the control group., Conclusion: The safe and reliable Chinese drug can enhance BMD, promote osteogenesis and inhibit bone absorption, hence treating osteoporosis with marked effect.