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601. Gastric histomorphology and secretory biochemistry after biliopancreatic diversion.

Author

Adami GF, Gianetta E, Sulfaro S, Aste H, Trulla LL, Botta G, Siccardi M, Guslandi M, and Scopinaro N

Subjects
Anastomosis, Roux-en-Y adverse effects, Follow-Up Studies, Gastritis, Atrophic etiology, Humans, Nitroso Compounds metabolism, Obesity therapy, Parietal Cells, Gastric pathology, Stomach pathology, Gastric Acid metabolism, Postgastrectomy Syndromes pathology, Stomach surgery
Abstract

When paired data are considered and unpaired results are compared with controls, it appears that no significant changes of gastric histomorphology occur following biliopancreatic diversion.

Published
1987

603. Malnutrition, nutritional support and total body composition.

Author

Adami GF, Summa M, Castagnola M, Marrante G, Camerini G, and Scopinaro N

Subjects
Amino Acids administration & dosage, Body Water analysis, Creatinine urine, Female, Humans, Jejunoileal Bypass adverse effects, Male, Obesity therapy, Protein Deficiency etiology, Protein Deficiency metabolism, Serum Albumin analysis, Sodium analysis, Transferrin blood, Body Composition, Parenteral Nutrition, Protein Deficiency therapy
Abstract

The nutritional status and total body composition of 33 patients with malnutrition after biliopancreatic bypass were studied. Body composition was evaluated directly by measurement of water and total sodium and indirectly by measurement of total body potassium. After nutrition with a parenteral nutritional support the conventional nutritional parameters were restored to the normal values (serum albumin and serum transferrin) and the parameters of body composition were markedly improved even though still altered with respect to healthy controls. Serum albumin and serum transferrin were shown to be very reliable indices of malnutrition but their normalization does not necessarily correspond to optimum body composition and thus to optimal normal nutrition.

Published
1988

604. [Effect of somatostatin on the rabbit Oddi's sphincter in vivo. Interrelation of somatostatin and cholecystokinin].

Author

Adami GF, Leandri R, and Sarles JC

Subjects
Animals, Dose-Response Relationship, Drug, Electromyography, Injections, Intravenous, Male, Perfusion, Rabbits, Ampulla of Vater drug effects, Cholecystokinin pharmacology, Somatostatin pharmacology, Sphincter of Oddi drug effects
Abstract

The action of somatostatin on the myoelectrical activity of the sphincter of Oddi was studied in anesthetized rabbits equipped with bipolar electrodes. The activity of the sphincter was recorded at the basal state and during 30 min after injection of somatostatin. After a bolus injection of somatostatin (1 to 8 micrograms/kg), the myoelectrical activity of the sphincter of Oddi decreased between the 2nd and the 10th min with a parallel decrease of the biliary pressure. These modifications were significant at the doses of 4 and 8 micrograms/kg only. There was a good dose-effect relationship. Moreover, the infusion of somatostatin (60 micrograms/kg/h) led to a decrease in sphincter activity. Bolus injection of cholecystokinin (2 UD/kg) under somatostatin infusion (60 micrograms/kg/h) induced an increase in the activity of the sphincter of Oddi. However, this activity never returned to basal levels.

Published
1986

605. Surgical revision of biliopancreatic diversion.

Author

Scopinaro N, Gianetta E, Friedman D, Adami GF, Traverso E, Vitale B, Castagnola M, Semino G, Summa M, and Bachi V

Subjects
Anastomosis, Roux-en-Y adverse effects, Anastomosis, Roux-en-Y methods, Body Weight, Female, Follow-Up Studies, Humans, Male, Postgastrectomy Syndromes etiology, Reoperation, Jejunostomy methods, Postgastrectomy Syndromes surgery
Abstract

Biliopancreatic diversion is a very effective method for weight reduction. In some instances it is too effective and needs to be revised.

Published
1987

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