Search

According to the theory of Health Locus of Control there is a correlation between the health locus of control and performing health-oriented activities. The aim of this work is to present the relationship between the level of students’ leisure time physical activity and the health locus of control. The study covered students from Poland, Slovakia and Ukraine. It comprised 3851 full-time students, aged 25 or less, studying at different departments (polytechnics, humanities, medical studies, mathematics and natural science as well as physical education). Two research tools were used in the study: MHLC form B (The Multidimensional Health Locus of Control Scale) and Minnesota Leisure Time Physical Activity Questionnaire MLTPAQ. The findings were processed by means of descriptive methods and the method of statistical inference. The average level of leisure time physical activity of women is lower than men’s by approximately one third. The students representing the medium level of physical activity (1000-1999 kcal/week) constituted the highest percentage (32.5 %). Regardless of gender, people with a higher level of physical activity are characterised by a higher level of internal locus of their health control. Together with the increase in the level of leisure time physical activity, the internal locus of health control increases as well. In the test group women constitute the highest percentage of people whose level of physical activity is below the recommended health standards (below 1000 kcal/week).

Pain may be defined as an unpleasant sensory and emotional experience, associated with actual or potential tissue damage. The leaves have social and ethnomedical applications. Tobacco is used traditionally to treat arches, snake bites, bowel complains, convulsions, nervous ailment and to cure/heal the pain of toothache when chewed (Melson, 1944). Therefore this study was designed to investigate the effect of chronic consumption of powdered tobacco on pain sensation using two groups of Swiss mice (control and test) weighing 18g-28g (n=15 each).The control received 100g of normal rodent chow, while the test group received 1g of powdered tobacco in 99g of rodent chow per day. Water was given ad libitum while daily food and water intake, as well as body weight changes, were monitored during the 31-day study. The tail flick and formalin tests were used to assess pain sensation. The results showed that the latency of tail flick did not differ between the test and control group. However, in the formalin test, the frequency of paw attention in both phases of the test was significantly lower (P< 0.05, 0.01) compared to the control group. The duration and frequency of grooming (P

The aim of the present study was to investigate the amounts of serum trace elements (copper, iron and zinc) and antioxidants (malondialdehyde, total antioxidant capacity and thiol group) in terrier dogs with six common behavior problems, namely, excessive activity, inappropriate elimination, fearfulness, destructiveness, aggression towards people, and aggression towards dogs. Information was collected from successfully completed questionnaires and two groups of dogs were selected: control group (dogs without any behavior problem, n = 14) and test group (dogs with at least one common behavior problem, n = 16). Serum total antioxidant capacity and zinc concentration in terrier dogs with behavior problem was significantly lesser than those in the control dogs (p

Understanding the genetic variation existing among individuals in relation to common diseases is necessary for classifying, comparing and managing them. In Nigeria, tuberculosis is common but we are not aware of any study on the association between phenylthiocarbamide (PTC) taste perception and tuberculosis. This present study was carried out to determine whether or not inability to taste PTC was associated with pulmonary tuberculosis. A total of 220 individuals comprising 113 tuberculosis patients (test group) and 107 apparently healthy subjects (control group) participated in this study. Tasters and non-tasters were determined among the participants using PTC taste strips. Of the 113 tuberculosis patients, 52 (46.0%) were tasters and 61 (54.0%) were non-tasters while 76 (71.0%) and 31 (29.0%) of the 107 control subjects were tasters and non-tasters respectively. Non-tasters of PTC were significantly more associated with tuberculosis patients than control subjects (χ 2 = 14.13, df = 1, p < 0.001). This study shows that inability to taste PTC is

Objectives: A pilot study to test whether a visual schedule system using picture communication symbols can help children with autism have successful routine dental cleaning visits. Study Design: 14 boys with autism between three- to eight-years-old presented to the dental clinic for four weekly consecutive dental appointments. Patients were randomly assigned to either the control group who received the tell-show-do method (i.e., standard of care), or the test group who received the tell-show-do method plus the visual schedule system. Results: Patients in the test group completed an average of 1.38 more steps, at 35.52 seconds per step faster, and with 18.7% lower levels of behavioral distress than those in the control group. Conclusion: The use of a visual schedule system, along with repeated weekly visits, showed some promise in helping children with autism successfully complete more steps, progress at a quicker rate, and exhibit lower levels of behavioral distress within a dental appointment, compared to a traditional tell-show-do approach.

Introduction Virtual planning and guided surgery with customized reconstructive plates are becoming more and more common for mandibular reconstruction with fibular free flaps. Although the literature describes many potential applications, no systematic analyses have been made about morphological results regarding computer-aided reconstruction compared to traditional freehand bent plate. Materials and methods In the present study, we propose a comparative study in this innovative field, analysing a case series of 30 CAD/CAM reconstructed mandibles, compared to traditional reconstructed mandibles, in terms of morphological results. All patients were evaluated by pre-operative and a post-operative CT scan. To evaluate the morphological results, several anatomical landmarks were measured on CT scan: 1) the midline deviation; 2) the amplitude variation, in grades, of the mandibular angle; 3) the bi-gonial diameter of the mandibular and 4) the chin protrusion. Results The mean differences registered between pre-operative and post-operative CT scan were significantly better for test group regarding mandibular angle (p = 0.034), bi-gonial diameter (p = 0.041), chin protrusion (p = 0.05). No significant differences were registered for midline deviation (p = 0.092). Conclusion CAD/CAM reconstructive technique appears to be a valid method to accurately restore the pre-operative morphological situation.

Целью исследования явилось изучение влияния цитофлавина на морфологические особенности сократительных кардиомиоцитов самок крыс, перенесших беременность, а также их потомства в условиях гемической гипоксии, индуцированной нитритом натрия (NaNO2). Эксперимент выполнен на 28 трехмесячных самках белых крыс линии Вистар и их 24 семидневных крысятах. На протяжении всей беременности и в течение 7 дней периода молочного вскармливания всем самкам ежедневно внутрибрюшинно вводили нитрит натрия (NaNO2) в дозе 5 мг/100 г массы тела. Самкам второй опытной группы дополнительно внутрибрюшинно вводили цитофлавин из расчета 0,5 мл/100 г массы тела животного. Выявлено, что гемическая гипоксия оказывает выраженное патогенное действие на сократительные кардиомиоциты и сосуды гемомикроциркуляторного русла, которое проявляется в виде гипоксических и ишемических повреждений, сопровождающихся нарушением целостности клеточных и митохондриальных мембран. Гистологическое и морфометрическое изучение миокарда животных первой опытной группы выявило достоверное уменьшение длины и площади кардиомиоцитов соответственно на 16,9 и 36,04 % (p ≤ 0,05), в то время как во второй группе животных, получавших цитофлавин, эти изменения носили менее выраженный характер, уменьшение длины и площади, в среднем, происходило на 8,2 и 18,6 %, соответственно (p ≤ 0,05). Применение цитофлавина позволяет снизить степень повреждения кардиомиоцитов у самок после гестации и новорожденных крысят, по-видимому, за счет его антиоксидантных и мембранопротекторных свойств.

The objective of the research was to find out the effect of LLLI irradiation on cow physiological and productivity parameters at the peak of lactation. For the purpose of the trial, a total of 40 clinically healthy cows were grouped in the following 2 groups: test (n=20) and control group (n=20).Twenty cows in the test group were exposed to laser irradiation for 30 seconds daily for 8 continuous days. Blood and milk samples were collected three times: before starting the trial (before irradiation), at the end of the trial (after 8 days of irradiation) and 14 days after the end of the trial. LLLI irradiation for 30 seconds (8 consecutive days) at the peak of cow lactation had no effect whatsoever on changes in the total blood protein content, aspartatamine transerase, leukocytes and phosphorus parameters in both the test and control group, however, the calcium concentration in the test group was found to remain stable over the entire course of the investigation.Was found to cause a statistically significant decrease in SCC in the test group as compared to the control group, and a statistically significant increase in milk protein content in the test group when compared to the control group.

This study aims to examine the effect of Convergence Tailed Occupational Therapy Activities Program (CTOTAP) which is customized to elderly people with mild cognitive impairment on their mental stability and social participation. A total of thirty elderly patients with mild cognitive impairment were randomly divided into a test group and a control group of 15 patients each, undergoing a total twelve sessions of the program (two sessions per week for six weeks) in three steps. In order to investigate the mental stability of the patients before and after the program, the Korean Geriatric Depression Scale (KGDS) was used while the Frenchay Activity Index (FAI) was used to explore the social participation of the patients. According to the findings of this study, there appeared to be an increase in the mental stability, social participation of the test group after the program. In addition, after the program there were differences between the test group and the control group in all of the mental stability and social participation. Therefore, the study has shown that the CTOTAP with customization has positive impact on the mental stability and social participation of patients with mild cognitive impairment.

Study objective: to reveal the relations between the indicators of physical and mental performance and the development of technical and tactical skills in fencers, to determine the significant criteria and tests for selecting students for health-improving and sports fencing groups. Methods: study and analysis of literature; pedagogical observations; physiological methods (physical performance by the Harvard step test with HSTI (Harvard step test Index) calculation, mental performance by the correction tables, special exercises to assess fencers’ technical and tactical skills); statistical methods. The reference group students (9 female fencers) had five workouts a week, the students (13 female students) of test group 1 (TG1) had 2 hours of physical training per week, the TG2 and TG3 (8 and 10 female students respectively) had 4 hours of fencing workouts per week. The TG2 had 4 months of fencing experience, and TG3 had one year and 4 months thereof. Results. The reciprocal effects of the performance indicators and the correlation between the indicators of technical and tactical skills of the student fencers allowed to establish the informative value of individual indicators for quality selection of students for the fencing group. The Harvard step test index and the standardized number of errors of the correction test can serve as the prognostic criteria for developing technical and tactical skills in student fencing.

A B S T R A C T This study aimed to determine the effectiveness of encouragement education on reducing exam stress and increasing self-efficacy of ninth grade female high school students by pretest - posttest experimental method with control group. Sample group consisted of 20 female students of the high schools of Bandar Lengeh in 2015-16 academic years and were chosen by cluster random sampling method and were placed randomly into two groups of test and control (10 people in each group). The scale of exam stress and perfectionism of participants in this research was evaluated by Ahwaz exam anxiety form (1996) and Lowenthal academic self-efficacy scale (1996) in the pre-test and post-test respectively and the test group participated in 10 sessions of encouragement education. The covariance analysis running on data showed that the amount of exam anxiety and self-efficacy of experimental group has a significant decrease and increase (P

Background: Children who have severe early childhood caries (S-ECC) weigh significantly less than caries-free children. The association between S-ECC and weight suggests that its timely treatment at early stages may preserve general health, in addition to preventing pain and infection. Objective: This study was conducted to evaluate whether children with untreated S-ECC had lower weight and height as compared with children with low caries and to evaluate whether full mouth rehabilitation of children with S-ECC resulted in the phenomenon of catch-up growth. Materials and methods: The weight and height of children with noncontributory medical histories and S-ECC (3-6 years) were compared with caries-free children, before and 6 months after full mouth dental rehabilitation. Results: Prior to dental rehabilitation, children with S-ECC had significantly less weight and height than their comparison counterparts (p < 0.001). Following therapeutic intervention, the test group children exhibited catch-up growth in relation to weight, as there was no significant difference in the body weight of the test and control groups (p = 0.171). Conclusion: Comprehensive full mouth rehabilitation of children with S-ECC results in catch-up growth, thus improving the overall health of the child. How to cite this article: Sachdev J, Bansal K, Chopra R. Effect of Comprehensive Dental Rehabilitation on Growth Parameters in Pediatric Patients with Severe Early Childhood Caries. Int J Clin Pediatr Dent 2016;9(1):15-20.

Many serious drug adverse events (AEs) only manifest well after regulatory approval. Therefore, the development of signaling methods to use with post-approval AE databases appears vital to comprehensively assess real-world drug safety. However, with millions of potential drug–AE pairs to analyze, the issue of focus is daunting. Our objective was to develop a signaling platform that focuses on AEs with historically demonstrated regulatory interest and to analyze such AEs with a disproportional reporting method that offers broad signal detection and acceptable false-positive rates. We analyzed over 1500 US FDA regulatory actions (safety communications and drug label changes) from 2008 to 2015 to construct a list of eligible signal AEs. The FDA Adverse Event Reporting System (FAERS) was used to evaluate disproportional reporting rates, constrained by minimum case counts and confidence interval limits, of these selected AEs for 109 training drugs. This step led to 45 AEs that appeared to have a low likelihood of being added to a label by FDA, so they were removed from the signal eligible list. We measured disproportional reporting for the final group of eligible AEs on a test group of 29 drugs that were not used in either the eligible list construction or the training steps. In a group of 29 test drugs, our model reduced the number of potential drug–AE signals from 41,834 to 97 and predicted 73 % of individual drug label changes. The model also predicted at least one AE–drug pair label change in 66 % of all the label changes for the test drugs. By concentrating on AE types with already demonstrated interest to FDA, we constructed a signaling system that provided focus regarding drug–AE pairs and suitable accuracy with regard to the issuance of FDA labeling changes. We suggest that focus on historical regulatory actions may increase the utility of pharmacovigilance signaling systems.

In the research project in my doctoral thesis I wanted to test the effects of a short preventive mental health program in secondary school. In 2007 there was established a longitudinal study with a test group and a control group (N=1671), built upon Solomon's design. Data was collected through questionnaires prior to intervention and at 1, 6, 12, and 24 months after the intervention. Effect sizes on the various indices are estimated in terms of (a) differences in improvements of total percentage scores and (b) Cohen's d. From t0 to t1, t2 and t3 the intervention group showed significantly greater progress in 6 out of 7 knowledge indexes, and 12 months after the intervention we found significant effects in reduction of mental health problems.

Aim: In this study, we aimed to assess the diagnostic accuracy and cost effectiveness of a first-step evaluation form, which we improved for patients administrat ed to the emergency department (ED) with non-traumatic acute abdominal and flank pain. Materials and Methods: Patients presenting with non-traumatic acute abdominal and flank pain complaints to the ED were included in this prospective cross-sectional cohort study in two consecutive months. Control group patients were evaluated with forms currently in use in our ED in the first month, whereas the evaluation of the test group was perfromed with the standardized evaluation form specifically designed for acute abdominal and flank pain in the second month. Results: Throughout both sessions, 1224 patients in total presented with non-traumatic abdominal and flank pain. Out of these, 285 of those enrolled in the first session, and 335 enrolled in the second session. Both control and test groups, which were similar demographically and with respect to vital symptoms/ findings, did not show any significant difference with respect to the examination/test and treatment. However, we observed a significant decrease in ED patient care expenses in the group evaluated with the new standardized form. Among them, those who were evaluated with the standardized form had relatively fewer complaints than those evaluated with the currently available evaluation form. Conclusion: Our results showed that utilization of a new standardized form for patients presenting with non-traumatic acute abdominal and flank pain significantly decreased patient care expenses for ED care; furthermore, they experienced relatively fewer complaints after discharge from the ED. (Eurasian J Emerg Med 2016; 15: 20-3)

Levornidazole is the levo-isomer of ornidazole with similar anti-anaerobic activity and lower central neurotoxicity compared with ornidazole. This open-label, parallel, randomised, multidose trial was conducted to compare the pharmacokinetics and safety of levornidazole following intravenous (i.v.) infusion 750mg every 24h (q24h) (test group, 12 subjects) versus 500mg every 12h (q12h) (reference group, 12 subjects) for 7 days in healthy Chinese volunteers. Following i.v. infusion for 7 days, the test group showed a 33.8% lower accumulation ratio (AR) and a 45.0% higher volume of distribution of levornidazole than the reference group. The cumulative urinary excretion rate of levornidazole during the 0-72h period (Ae0-72) was 16.6±20.9% in the test group and 24.2±5.7% in the reference group. The metabolite M1/parent and M4/parent ratios were, respectively, 2.18±0.77% and 2.94±0.37% in test group and 3.15±1.09% and 3.18±0.34% in the reference group. The Ae0-72 of M1, M2 and M4 were all

This study aimed to enhance the applications of dates as a food material that can be utilized and stored easily by improving the inefficient process of the traditional cooking procedure. To this end, this study investigated the physico-chemical and nutritional properties of jujube pulp powder, and compared the traditional and newly developed methods of making yakbap, yakpyon, and jujube porridge. According to the analysis of physical and chemical properties, the jujube pulp powder contained 5.4% moisture, 2.6% crude ash, 6.6% crude protein, 0.35% crude fat, and 4.7% crude fiber. The water activity was 0.95% in jujube pulp while it was 0.24% in jujube pulp powder. In addition, the jujube pulp powder had a total sugar content of 70.4% and reducing sugar content of 6.3%. The vitamin C was content was estimated to be 68.5 mg/100 g in the jujube pulp powder and the jujube pulp contained 6.2 g/100 g of dietary fiber. Major minerals were K, Mg, and Ca. After appointing jujube pulp powder (new method) to a test group and jujube pulp (traditional method) to a control group, the sensory evaluation and acceptance testing were conducted for yakbap, yakpyon, and jujube porridge. As a result, there was no significant difference in any sensory factors tested (p

Emblica officinalis fruit possesses varied medicinal properties including cytoprotective antimicrobial, antioxidant, antiresorptive and antiinflammatory activity. The present study aimed to investigate the effect of subgingival application of indigenously prepared E. officinalis (Amla) sustained-release gel adjunctive to scaling and root planing (SRP) on chronic periodontitis. Forty-six patients (528 sites) were randomly assigned to control group (23;264): SRP +placebo gel and test group (23;264): SRP + 10% E. officinalis gel application. Periodontal parameters: plaque index, gingival index, probing pocket depth (PPD), clinical attachment level (CAL) and modified sulcus bleeding index (mSBI) were assessed at baseline, 2 and 3-month post-therapy. Forty patients (470 sites) completed the trial. When test and control sites were compared, significantly more reduction in mean PPD, mSBI, number of sites with PPD = 5-6 mm, PPD ≥ 7 mm, CAL ≥ 6 mm and greater CAL gain were achieved in test sites at 2- and 3-month post-therapy (p

Background: The therapeutic safety of herbal medicine is a major concern for consumers and users. After studying the effects of linseed on hair growth in rabbits, the turn is to evaluate its safety by the observation of some clinical, biological and anatomo-pathological aspects. Materials and Methods: A study was conducted during a period of three months on two groups of rabbits (control and test). Test group daily received feed supplemented with 3g of ground linseed while the control animals received the same feed without any additives. Weekly, rabbits were weighed and monthly blood samples were taken. By the end of the trial, liver and kidneys biopsies were analyzed for histological and cytological lesions. Results: There was no significant improvement in weight gain in the test group rabbits, in which biochemical parameters had differentially evolved with a decrease in their Glycemia and cholesterolemia. There were also no modifications in their serum hepatic and renal marker enzymes and their liver and kidneys exhibited noticeably normal histology without any anatomically detectable anomalies. Conclusion: These findings confirm that prolonged linseed ingestion in rabbits is safe.

Constriction is a prey-immobilization technique used by many snakes and is hypothesized to have been important to the evolution and diversification of snakes. However, very few studies have examined the factors that affect constriction performance. We investigated constriction performance in ball pythons (Python regius) by evaluating how peak constriction pressure is affected by snake size, sex, and experience. In one experiment, we tested the ontogenetic scaling of constriction performance and found that snake diameter was the only significant factor determining peak constriction pressure. The number of loops applied in a coil and its interaction with snake diameter did not significantly affect constriction performance. Constriction performance in ball pythons scaled differently than in other snakes that have been studied, and medium to large ball pythons are capable of exerting significantly higher pressures than those shown to cause circulatory arrest in prey. In a second experiment, we tested the effects of experience on constriction performance in hatchling ball pythons over 10 feeding events. By allowing snakes in one test group to gain constriction experience, and manually feeding snakes under sedation in another test group, we showed that experience did not affect constriction performance. During their final (10th) feedings, all pythons constricted similarly and with sufficiently high pressures to kill prey rapidly. At the end of the 10 feeding trials, snakes that were allowed to constrict were significantly smaller than their non-constricting counterparts.

This study is investigating the impact of “Philosophy for Children” Program on the reduction of the symptoms of psychosomatic disorders in children aged 9 to 11 years in Iran. The sample of the study consists of 45 primary school boy students who were randomly selected using multistage random cluster sampling from among 19 districts of Education. This is a Quasi-experimental method research with experimental and control groups. Research tool in this study was Achenbach questionnaire form YSR (Youth Self-report). At first, using this questionnaire, all third and forth graders in two schools were selected by screening in which 45 ones got a score which showed psychosomatic disorders that all of them were eager to take part in the study. The test group, during a 12 sessions in a week, for 1 hour, participated in community of philosophical inquiry-the method of “Philosophy for Children” Program-with a training coach. After the end of the sessions, Achenbach’s re-test, on both control and test groups, was taken to determine the effect of holding the “Philosophy for Children” Program on psychosomatic disorders. The results of this study showed that the implementation of this program has a significant effect in reducing symptoms of psychosomatic disorder of test group.

Background: Haemostaticab normalities were associated with hyper thyrodism patients. This study aimed to assess the D-dimer levels which indicate the hypercoagulable state in Sudanese patients with hyper thyrodism. Material and Methods: A descriptive analytical case study was conducted in faculty of medical laboratory science, Alneelain University, Khartoum, Sudan. A total of 80 participants were selected for this study, 40 of them were patient known diagnosed by hyperthyroidism as a test group; 20 (50%) were female and 20 (50%) were male; their mean age 36.3 years. Other 40 participants were normal healthy individual as control group. The plasma D-dimer level was measured by using semi-automated coagulometer (MISPA-i2Reagent-SWITZERLAND). Data were analyzed by using statistical package for social sciences (SPSS) Version 20. Results: In this study, the plasma D-dimer level has statistically significantly higher in hyperthyroidism patient compared to normal healthy control group (mean ± SD 0.5008 ± 0.239 vs. 0.5 ± 0.618 mg/dl with P value 0.00), respectively. Conclusions: The present study revealed that the D-dimer levels were statistically significant higher in hyper thyroid patients.

Background: Soluble ST-2 has considerable prognostic value and is used as an aid for risk stratification in identifying patients who are at high risk of cardiovascular disease. The main objective of the study was to analyze the level of soluble ST-2 biomarker in patients with acute myocardial infarction and chronic stable angina patients and secondly to evaluate the cardiovascular outcomes after 30 days. Methods: A total of 71 patients were enrolled into the study, patients were divided into two groups of which 50 patients were in test group (AMI patients) and the remaining 21 patients were in the control group (chronic stable angina). Then, 5ml of blood was collected from the patients and plasma soluble ST-2 was estimated from the sample using ELISA technique. Patients were then followed up to 30 days to ascertain the development of major adverse cardiovascular outcomes. Results: The median concentration of soluble ST-2 in test group was found to be 213.46pg/ml and in control group was found to be 124.53 pg/ml. Soluble ST-2 correlated significantly with left ventricular ejection fraction (LVEF) between the two groups (P value=0.01). Measurement of soluble ST-2 early after MI assists in the prediction of adverse cardiovascular events. In this study, soluble ST-2 was found to be higher in patients with acute myocardial infarction and also in patients with poor ejection fraction. Conclusions: Soluble ST-2 is a novel cardiovascular biomarker that is elevated in patients with acute myocardial infarction.

Background: Depression is a common chronic recurrent syndrome, characterized by apathy, loss of energy, retardation of thinking and activity, as well as profound feelings of gloominess, despair and suicidal ideation. The present study aimed to evaluate the antidepressant activity of synthesized novel furan compound by using forced swimming test (FST) and tail suspension test (TST). Methods: The antidepressant activity was studied in albino mice using FST and TST. Fluoxetine (20 mg/kg) were used as standard drugs and test drug novel furan compound (5, 10, 20 mg/kg) was used as test drug. A total of 60 mice were selected for the study and utilized 30 mice in each model. Animals were divided into five groups consisting of 6 animals in each. Control group received 10% tween 80 orally; standard group received fluoxetine 20 mg/kg orally; test group 1 received 5 mg/kg substituted furan compound orally; test group 2 received 10 mg/kg substituted furan compound orally; test group 3 received 20 mg/kg substituted furan compound orally. Results: In FST the low dose test compound had shown the percentage inhibition of 75.5% which was comparable to percentage inhibition of standard drug fluoxetine -82%. In TST the test group-1 had produced 66.6%, test group-2 83.3% and test group-3 produced 100% protection against passive behavior (immobility). The percentage of protection produced by highest dose was equal to standard drug fluoxetine against passive behavior. Conclusions: It can be concluded that the test drug has produced significant inhibition in duration of immobility by FST and also had significant protection against passive behavior. Hence substituted furan had potential antidepressant activity.

Background: The combination of biomaterials, bone graft substitutes along with guided tissue regeneration (GTR) has been shown to be an effective modality of periodontal regenerative therapy for infrabony defects. Therefore, the present randomized controlled clinical study was undertaken to evaluate the effectiveness of hyaluronic acid (HA) in combination with bioresorbable membrane for the treatment of human infrabony defects. Materials and Methods: Twenty four infrabony defects in 20 systemically healthy patients were randomly assigned to test (HA in combination with bioresorbable membrane) and control (bioresorbable membrane alone) treatment groups. Probing pocket depth (PPD), relative attachment level, and relative gingival margin level were measured with a computerized Florida disc probe at baseline and at 6 months follow-up. Radiographic measurements were also evaluated at baseline and at 6 months of postsurgery. Results: At 6 months, the mean reduction in PPD in test group and control group was 4.52 mm and 2.97 mm, respectively. Significantly higher clinical attachment level with a gain of 2.20 mm was found in the test group as compared to control group. In addition, statistically significant greater reduction of radiographic defect depth was observed in the test group. Conclusion: Regenerative approach using hyaloss in combination with GTR for the treatment of human infrabony defects resulted in a significant added benefit in terms of CAL gains, PPD reductions and radiographic defect fill, as well as LBG, compared to the GTR alone.

Background: This study investigated the effects of hydro-ethanolic leaf extract of Fleurya aestuans (FA) on some female reproductive hormones in female albino wistar rats. Methods: Thirty-two (32) rats weighing 120 to 200g were grouped into four of eight rats each. After two weeks of acclimatization, group 1 served as the control group. Groups 2, 3 and 4 served as the test groups and were orally administered with (75, 150 and 300) mg/kg body weight of hydro-ethanolic leaf extract of Fleurya aestuans (FA) respectively, for 42 days. The animals were allowed access to water and feeds ad libitum. At the end of treatment, the animals were properly sedated and blood samples were collected via cardiac puncture. The blood samples were centrifuged and serum obtained was used to determine the concentrations of follicle stimulating hormone (FSH), luteinizing hormone (LH), estrogen and progesterone using the ELISA method. Also, the ovaries of each rat were harvested and fixed for histological studies. Raw data were analyzed using SPSS version 20.0. Results: The hydro-ethanolic leaf extract of F. aestuans significantly (P

Background: The aim of this clinical trial was to evaluate the effectiveness of systemic tinidazole as an adjunct to nonsurgical periodontal therapy in the treatment of chronic periodontitis in smokers. Materials and Methods: Sixty smoker participants with history of moderate to severe generalized chronic periodontitis were selected. Gingival index (GI) Leo and Silness, plaque index (PI) O'Leary, bleeding index (BI) Lenox, pocket depth (PD), recession, and clinical attachment level (CAL) were measured at the baseline and 6 weeks after initial periodontal treatment. Thirty participants were randomly assigned to full-mouth scaling and root planning (SRP) + placebo (control group) and 30 participants were assigned to full-mouth SRP + tinidazole (test group). Results: Both test and control groups showed significant improvement in clinical parameters. Comparison of reduction in PI, GI, BI, PD, and CAL, between two groups, was statistically significant 6 weeks after baseline visit (P < 0.001). The improvements in clinical periodontal parameters were significantly more in test group. Conclusion: Smokers with chronic periodontitis benefited from adjunctive therapy, consisted of systemic tinidazole and SRP.

Background: Necrotising enterocolitis (NEC) is primarily a disease of premature infants, but may also be present in 10% of term and near term babies. It is the most common gastrointestinal (GI) medical/surgical emergency occurring in neonates. The objective was to study the r ole of oral probiotics in prevention of necrotising enterocolitis in preterm neonates. Methods: Prospective randomized controlled trial was done in tertiary care centre in Northern India for a period of 18 months. 300 preterm neonates, 150 in the test group and 150 in the control group were studied . The neonates in the test group were fed probiotics with breastmilk twice daily till they reached oral feeds. The neonates in the control group were fed breastmilk alone. Incidence and severity of NEC were measured. Results: 300 neonates (study group n = 150, control group n = 150) were randomized. The incidence of NEC was lower in test group (2.7%) than the control group (9.3%). The severity of NEC was reduced in test group (stage 2 and 3- 0.7%) than the control group (stage 2 and 3-6%). The mortality was also significantly lower in the intervention group (0% versus 20%). Conclusions: Probiotic supplementation has reduced the incidence and severity of necrotising enterocolitis in preterm neonates.

Purpose. To evaluate the soft tissue stability around single implants inserted to replace maxillary lateral incisors, using an innovative 3D method.Methods. We have used reverse-engineering software for the superimposition of 3D surface models of the dentogingival structures, obtained from intraoral scans of the same patients taken at the delivery of the final crown (S1) and 2 years later (S2). The assessment of soft tissues changes was performed via calculation of the Euclidean surface distances between the 3D models, after the superimposition of S2 on S1; colour maps were used for quantification of changes.Results. Twenty patients (8 males, 12 females) were selected, 10 with a failing/nonrestorable lateral incisor (testgroup: immediate placement in postextraction socket) and 10 with a missing lateral incisor (controlgroup: conventional placement in healed ridge). Each patient received one immediately loaded implant (Anyridge®, Megagen, Gyeongbuk, South Korea). The superimposition of the 3D surface models taken at different times (S2 over S1) revealed a mean (±SD) reduction of 0.057 mm (±0.025) and 0.037 mm (±0.020) fortestandcontrolpatients, respectively. This difference was not statistically significant (p= 0.069).Conclusions. The superimposition of the 3D surface models revealed an excellent peri-implant soft tissue stability in both groups of patients, with minimal changes registered along time.

Introduction. Standardized protocols for perioperative management of patients are increasingly used in colorectal surgery. We compared the results of right-sided hemicolectomy in elderly patients before and after implementation of this protocol. Materials and methods. The results of a prospective database of the department of surgical oncology of Treatment and Rehabilitation Center for 2009–2016 years were analyzed. A comparative analysis of 86 case of elective right-sided hemicolectomy was performed in patients aged 60 years and over as a part of standardized protocol for perioperative management of patients, and 34 similar surgeries carried out earlier without compliance with the protocol. Clinically, there was no significant differences between groups. Results . In the study group we revealed statistically significant decrease in the number of sever (grade III–V by Clavien–Dindo) postoperative complications and mortality from 33 % to 13 % and from 12 % to 1 %, respectively. Also, despite the fact that surgical operations in the test group were carried out by less experienced surgeons, introduction of the unified surgical technique reduced median duration of the surgery from 185 to 165 minutes. Conclusion. Introduction of the standardized protocol for perioperative management of elderly and old patients, that need right-sided hemicolectomy, reduces the number of complications and lethal cases.

Background: It has been estimated that 75% of all females experience at least one episode of Candida vaginitis with approximately 40-50% reporting a recurrence during their lifetime. The symptoms of vulvovaginal candidiasis are often painful and uncomfortable to the patient. The objective of this study was to assess the efficacy of Amla and Shibe yamani in the management of Candida vaginitis. Methods: This randomized, single blind, standard controlled study was done to compare the efficacy of Amla and Shibe yamani against fluconazole and 2% miconazole on diagnosed subjects of Candida vaginitis. Test group (n=30) received Amla with honey orally and Shibe yamani intra-vaginally at bed time for 3 wks. Whereas control group received standard regime of single dose fluconazole 150 mg orally and 5g of miconazole 2% cream intravaginally for 7 days. The primary outcome measure was relief in the vulvovaginal pruritus (reduction in 5D itch score). Secondary outcome measures included change in wet mount and improvement in vaginal discharge. Results: Vulvovaginal pruritus significantly decreased (P

Resumen:El presente estudio tuvo como propósito identificar el efecto de la intervención en Terapia de Aceptación y Compromiso (ACT) sobre la resistencia aeróbica y conducta de evitación experiencial en un grupo de marchistas de Bogotá. Se utilizó un diseño pretest-postest con grupo control. La muestra estuvo compuesta por diez marchistas de ambos sexos, con un promedio de edad de 16.70 y un rango entre los 15 y 20 años de edad, pertenecientes a la Liga de Atletismo de Bogotá. Se eligieron por conveniencia. Se emplearon como instrumentos de medición el test de los 3000 m y el Cuestionario de Aceptación Acción (AAQ). La intervención en ACT se realizó en cuatro sesiones en las que se desarrollaron los contenidos definidos por los autores de la intervención (Wilson y Luciano, 2002). Para el análisis de los datos, se empleó estadística no paramétrica a través de la prueba U de Mann-Whitney. Los resultados señalan una mayor resistencia aeróbica en la prueba de los 3000 m en el postest del grupo experimental con respecto al grupo control, así como una mayor aceptación de los eventos internos negativos. Abstract:The purpose of the present study was to identify the effect of an Acceptance and Commitment intervention Therapy (ACT) on aerobic endurance and experiential avoidance behavior of a group of walkers in Bogota. This study used a pretest-posttest design with a control group. The sample consisted of ten walkers of either sex, with an average age of 16.70 years, and a range between 15 and 20 years old, belonging to the Bogotá Athletics League. The participants were chosen as a convenience sample. The instruments used were the 3000-meter test and the Acceptance and Action Questionnaire (AAQ). The ACT intervention was conducted in four sessions, where they developed the contents defined by the authors of this intervention (Wilson and Luciano, 2002). Non-parametric statistics were used for data analysis, by means of the Mann-Whitney U. The posttest results indicate a greater aerobic resistance in the 3000-meter test for the test group in comparison to the control group. Likewise the experimental group shows a greater acceptance for negative internal events.

Johar (Cassia siamea Lamk.) leaves widely used as a traditional medicine. Johar leaves contain chemical compounds such us alkaloids, tannins, saponins, flavonoids, sitosterol and barakol which have effect of treatment for several diseases including inflammatory. This study aims to determine anti-inflammatory effect of chloroform fraction C.siamea leaves. This study was conducted using 15 Wistar rats were divided into 5 groups: control group who were given suspension of Na.CMC 1% w / v, the comparison group were given diclofenac sodium suspension 0.35 mg / kg, the test group dose of 75 mg / kg, the test group dose of 150 mg / kg and a test group of 300 mg / kg. Evaluation of anti-inflammatory activity was done by measured initial volume of the foot all test animal then given the drug orally according to dosage of its group. After 30 minutes, each group made inflammatory by induced karagen 1% 0.1 mL by intraplatar. Furthermore, inflammation’s degrees was measured every hour for 8 hours. The results obtained show that after 2 hours, inflammatory of the control group Na.CMC had increased much higher compared to the other groups. This is shows that Na.CMC doesn’t have effects anti-inflammation. The comparison group diclofenac sodium gave the best inhibitory effect that have been shown from an increase volume of feet smaller than the test group chloroform fraction of Johar leaves. While in chloroform fraction of Johar leaves test group, group with dosage 75 mg/kg gave an inhibitory effect better than the other test group dosage.

Resumo. Criadouros naturais de Aedes aegypti Linnaeus podem ser encontrados em bromelias e outros vegetais que apresentem estrutura capaz de armazenar a agua. A produtividade dos criadouros esta ligada ao volume e a capacidade de manutencao de agua, a oferta de nutrientes e a densidade larval e ao numero de folhas do vegetal. Ha controversias entre os pesquisadores sobre o encontro de formas imaturas de Ae. aegypti na agua dos reservatorios de bromelias. Este estudo dedicou-se a observacao da eclosao de ovos e do desenvolvimento de Ae. aegypti em agua de tanques de bromelia Aechmea fasciata (Lindley) Baker e Neoregelia compacta (Mez) L.B. Smith . Para cada uma das especies de bromelias tres tipos de grupos foram utilizados: dois grupos controles, um contendo agua de rega e outro grupo com agua dos reservatorios das bromelias sem a presenca da microfauna; e o grupo teste, contendo agua dos tanques com a presenca da microfauna. Os resultados dos experimentos em agua de A. fasciata em presenca da microfauna apresentaram 45% de mortalidade larval; em agua de N. compacta , em presenca da microfauna, apresentou inibicao de 100% de eclosao de ovos de Ae. aegypti. Ha necessidade de informar e educar a populacao sobre o cultivo de bromelias, sobre a fauna fitotelmata competidora e predadora nos reservatorios e sobre a interacao entre aquele ambiente e as larvas do Ae. aegypti. Development , Availability and Mortality of Immature Aedes ( Stegomyia ) aegypti, Linnaeus, in Water of Two Species of Bromeliads: Bibliographic and Experimental Study Abstract. Natural breeding of Aedes aegypti Linnaeus can be found in bromeliads and other plants that have a structure capable of storing water. The productivity of the breeding is linked to the volume and the maintenance of the water content, the nutrients supply, the larval density and the number of leaves of the plant. Researchers do not reach an agreement about the development of immature forms of Ae. aegypti in bromeliads water reservoirs. The study focused on the observation of the eggs hatching and development of Ae. aegypti in bromeliads Aechmea fasciata (Lindley) Bakerand Neoregelia compacta (Mez) L.B. Smith water tanks. For each bromeliad specie three groups were used: two control groups, one containing irrigated water and another containing bromeliads reservoirs water without microfauna presence; and test group, containing bromeliads reservoirs water with the microfauna presence. The A. fasciata water with microfauna showed 45% of larval mortality. The N. compact water with microfauna presented 100% of Ae. aegypti eggs hatching inhibition. It is necessary to inform and educate people about bromeliads growing, the competitive predator phytotelmate fauna in theirs water reservoirs and the interaction between this environment and the larvae of Ae. aegypti.

Schneiderian membrane perforation (SMP) is the most common complication during sinus floor elevation (SFE). Conventional methods to repair SMP, such as using a collagen barrier, may be clinically demanding. The aim of the present study was to compare the effects of collagenated bone substitute materials with and without a collagen barrier to repair SMP during SFE in terms of new bone formation and dimensional stability. In 12 rabbits, intentional SMP was made during bilateral SFE. The rabbits were randomly assigned under two groups: the control group, in which the sinus was repaired with a collagen barrier, and the test group, in which the sinus was repaired without a collagen barrier. Collagenated bone substitute material was grafted in both groups. Healing periods of 2 weeks and 4 weeks were provided in both groups. There were no adverse clinical events. Histology revealed that the Schneiderian membrane had atrophied with loss of cilia and serous glands in both groups at 4 weeks. Histomorphometry revealed that the newly formed bone (test: 0.42 &plusmn, 0.17 mm2, control: 0.36 &plusmn, 0.18 mm2 at 2 weeks, test: 1.21 &plusmn, 0.36 mm2, control: 1.23 &plusmn, 0.55 mm2 at 4 weeks) or total augmented area did not significantly differ between the two groups at either time points (p &gt, 0.05). In conclusion, collagenated bone substitute material without a collagen barrier demonstrated similar new bone formation and dimensional stability as that with a collagen barrier in repairing SMP.

When there is an ankle sprain injury the athlete has decreased functional ability and decreased instability of the ankle joint. One of the actions used to reduce the risk of injury and increase the performance of athletes is by providing a Neuromuscular Training Program (NMT). This study to prove the effect of the provision of the Neuromuscular Training Program on the functional performance. This study used a Randomized Pre Test and Post Test Group Design study design. Respondents of this study were male soccer athletes, amounting to 18 athletes who met the inclusion criteria, then divided into 2 groups randomly, each group consisted of 9 respondents. The study showed that there were differences in improvement in functional performance after the administration of the Neuromuscular Training Program in male soccer athletes with a history of ankle sprain. In the treatment group shows the results of functional performance (SLHT) with a value of p = 0,000 indicates a significant effect. Then the results of subjective functional performance measurements using Cumberland Ankle and Instability Tools (CAIT) in the treatment group showed the results of functional performance (CAIT) with a value of p = 0.005. From the results of the study that there were differences and improves in functional performance after the administration of the Neuromuscular Training Program in male soccer athletes with a history of ankle sprain.

This study aims to determine: (1) the differences in learning achievement of speaking skills in Biography between class VII students of SMP Negeri 18 Jambi City who were taught using poster media with students who were taught without using poster media; (2) the effectiveness of poster media in learning biography on speaking skills of class VII SMP Negeri 18 Jambi City. This research is a quasi experimental study. The research design was a pre-test and post test group. The subjects in this study were all grade VII students of SMP Negeri 18 Jambi City. Samples were taken using simple random sampling technique. The group consisted of two classes, namely F as an experimental group of 32 students and D as a control group of 32 students. The research data was taken using a test, namely the speaking test. The validity used in this research is content validity and construct validity. The reliability used in this study was Alpha Cronbach's reliability. While the research data were analyzed using t-test and gain score. The results of this study resulted in (1) the value of tcount> ttable, namely 2.314> 2.011 with df = 47 at the 5% significance level. The results of these calculations indicate that there is a difference in the learning achievement of students' biographical speaking skills between classes taught using poster media and those taught without using poster media; (2) the calculation of the mean gain score, the experimental class has an average gain score of 0.303 which is greater than the average gain score of the control class of 0.225. Thus it can be concluded that learning using poster media is more effective in learning biographical speaking skills for seventh grade students of SMP Negeri 18 Jambi City.

This study aimed at evaluating the impact of a diet supplemented with Guazuma ulmifolia leaves on the productive performance and gastrointestinal parasites (GI) eggs/oocysts shedding of sheep (Pelibuey breed). Twenty-two non-lactating ewes were used. They were randomly allocated to two similar groups in terms of age, weight, body condition score (BCS), and GI parasites status. For 30 days, while the control group (G0) was given basic forage hay of Cynodon nlemfuensis, the test group (G1) received a blend of G. ulmifolia fresh foliage and C. nlemfuensis hay (respectively 30 and 70% of the diet on a DM basis). Animals were housed in separate covered pens. Quantitative coprological analysis was performed. Weight and BCS were evaluated. The daily feed amounts given and refused were measured in order to assess nutrient components intake (minerals, energy, and nitrogen). The results showed no significant differences between G1 and G0 regarding the anthelmintic and anticoccidial effects (p = 0.57, p = 0.91, respectively). Similarly, no significant overall impact on weight and BCS during the experiment (p = 0.77, p = 0.32, respectively) was observed. Nevertheless, concerning the bromatological analysis of G. ulmifolia, its use as a diet supplement to address protein and mineral deficits due to a poor-quality diet is fully justified.

Background: Intraoral scanners (IOSs) in implantology represent a viable approach for single teeth or partial arches. However, when used for complete edentulous arches or long-span edentulous areas, it has been demonstrated that there is a need for improvement of IOS-related techniques. Therefore, the aim of this in vitro study was to assess the trueness and precision of a complete arch digital impression on four and six implants taken with or without a customized, prosthetic-based impression template. Materials and Methods: Two experimental models were prepared, representative of a complete edentulous mandible restored with four and six implants with built-in scan abutments. Models were scanned with (test group, TG) or without (control group, CG) the prosthetic-based impression template. Eight scans were taken for each model. The time needed to take impressions, error, trueness, and precision were evaluated. A statistical analysis was performed. Results: In the case of four implants, the time needed for the impression was 128.7 &plusmn, 55.3 s in the TG and 81.0 &plusmn, 23.5 s in the CG (p = 0.0416). With six scan abutments, the time was 197.5 &plusmn, 26.8 and 110.6 &plusmn, 25.2 s in the TG and CG, respectively (p = 0.0000). In the TG, no errors were experienced, while in the CG, 13 impressions were retaken due to incorrect stitching processes. In the four-implant impression, the mean angle deviation was 0.252 &plusmn, 0.068&deg, (95% CI 0.021&ndash, 0.115&deg, ) in the CG and 0.134 &plusmn, 0.053&deg, (95% CI 0.016&ndash, 0.090&deg, ) in the TG. The difference was statistically significant (p = 0.002). In the six-implant impression, the mean angle deviation was 0.373 &plusmn, 0.117&deg, (95% CI 0.036&ndash, 0.198&deg, ) in the CG and 0.100 &plusmn, 0.029&deg, (95% CI 0.009&ndash, 0.049&deg, ) in the TG (p = 0.000). In the TG, there were no statistically significant differences in the mean angle deviation within the group (p &gt, 0.05), but there were in the CG. A colorimetric analysis showed higher deviations from the original model for the six-implant impression without a prosthetic template. Conclusions: Although all of the impressions exhibited deviation from the original model in the range of clinical acceptability, the prosthetic-based impression template significantly improved the trueness and precision of complete edentulous arches rehabilitated with four or six implants, making the complete arch digital impression more predictable.

A utilização de plantas com fins medicinais usadas para tratamento, cura e prevenção de doenças é considerada uma prática milenar da humanidade. Dentre os parâmetros atuais, destaca-se a obesidade como sendo um problema de saúde pública mundial nos países desenvolvidos e em desenvolvimento. O estudo se propõe a delinear o potencial toxicológico, assim como, avaliar a caracterização físico-química e fitoquímica da Garcínia cambogia, a fim de contribuir para utilização segura dessa planta. Foram realizadas análises físico-químicas, fitoquímicas e toxicológica, a fim de caracterizar a qualidade e segurança dos extratos obtidos da Garcínia cambogia. Observou-se que o teor de material estranho, pH, cinzas totais e cinzas insolúveis em ácido estavam de acordo com os limites estabelecidos. Os valores para umidade estavam acima do permitido. Na triagem fitoquímica apresentou resultados negativos para flavonóides e taninos, e resultado positivo para saponinas. Para o teste de toxicidade aguda in vivo o extrato foi categorizado como sendo “categoria 5” (2000 a 2500 mg/kg), e a toxicidade letal aguda – DL50% estimada em 2500 mg/kg, sendo considerado atóxica. Na avaliação da toxicidade sistêmica não foram observadas diferenças significativas entre os animais do grupo teste e os do grupo controle. Não foram observadas alterações macroscópicas dos órgãos após os 14 dias de experimento, demonstrando ausência de toxicidade aguda. Com os resultados obtidos foi possível contribuir para um conhecimento mais aprofundado da Garcínia cambogia, com informações mais detalhadas do seu potencial toxicológico.

The application of advanced technology and building user's different behavior decisions has an important impact on the performance of fire emergency management. Currently, although many studies have focused on developing advanced technology and improving fire emergency management effectiveness, advanced technology often fails because of the inapplicability or non-use of the technology. Therefore, it is necessary to combine building users' behavior decisions with advanced technology and propose fire response modes that are adapted for such users. Based on the Building Information Modeling (BIM) platform, this paper builds a fire emergency management system (FEMS) that considers the behavior decisions of building users (behaviors such as escape, wait for rescue, and fire extinguishing). We develop a database management module and four functional modules that include fire intelligence-monitoring, fire-warning, fire-response, and fire-treatment. The system realizes the dynamic monitoring of building fires, the judgment of fire category, the locations of users, and the ability to view fire-points in a three-dimensional (3D) model. In addition, this system can also plan optimal action routes according to different building user's decisions, while the application (app) provides visual route guidance. Through a fire scene simulation experiment, we show that the moving distance of the Test Group equipped with FEMS is 30% shorter than the Control Group, and the total time spent is reduced by 48%. Also, the performance of each type of decision-makers' behavior in the Test Group was better than that of the Control Group.

Background: Lysine is a basic amino acid which is not integrated inside the body. It is integrated in higher plants through biochemical pathways. Numerous clinical studies have revealed that amino acids assume a significant part in rushing the way toward wound recuperating by improving the nearby blood supply as growth factors. Aim and Objectives: This investigation intended to evaluate the wound healing potential, efficacy, and tolerability of lysine cream (15%) in diabetic foot ulcer assessed by assessing scale. Materials and Methods: A randomized, open-label, and interventional study was directed on 40 subjects (participants) with diabetic ulcers. Participants were grouped into two groups, control and test. The control group (n = 20) was treated with standard treatment and the test group was treated with standard treatment alongside lysine cream (15%) twice every day. Wound healing in the participants was assessed by the assessing scales. Results: A total of 40 participants were allotted into two groups. The results expressed as mean ± standard deviation values imply the size and depth of the foot ulcer from the 1st week to the 8th week. Both the groups showed a significant increase the ulcer healing and decrease the pressure of foot ulcer of over a period of 8 weeks. The assessment of the 1st week showed no significant ulcer healing and its pressure. The overall outcome indicated that the lysine-treated group extensively reduced each of the parameters favoring wound healing than the standard therapy alone (control group). Furthermore, there was no significant difference in the blood glucose levels in both study groups. Conclusion: Treatment with additional lysine cream considerably improved wound recovery in diabetic foot ulcer patients when compared to the standard therapy alone.

Objective: the aim of the research is to make a comprehensive assessment of the prebiotic feed additive effect on calves. The experiment was carried out in work conditions on 10 black-and-white Holstein-cross calves at the age of 2 to 32 days. To conduct the experiment, an experimental group and a test group have been formed. Each group has included five milk-fed calves at the age of 2 days and older. All the calves have been given colostrum in their first 2–4 hours after birth and then they have been fed three times a day, at regular intervals. The following methods are used: clinical, microbiological, immunological and statistical. The article describes the prebiotic lactulose-based additive effect on the intestinal microbiocenosis development in one-month old calves and presents an assessment of humoral and cellular components of natural resistance in calves. The research results show a positive effect of the lactulose-based additive on the symbiotic microflora of the gastrointestinal tract that improves the natural resistance of the body and the physiological status of animals, reduces the disease duration and contributes to an increase in weight gain. After feeding the calves with the lactulose-containing preparation during their first month of life, the weight gain of each calf in the experimental group has been 21.8 kg, or + 51 % of the initial weight and in the test group 19.0 kg, or + 41 % of the initial weight. Feeding the additive has an impact on the two components of natural resistance: serum bactericidal activity in the experimental group calves has been higher by 17.8 % and the phagocytosis activity has been higher by 30.5%, compared to the test group calves. Feeding calves with the lactulose-containing additive helps reduce the illness duration, stimulates the increase in live weight and affects the natural resistance level of newborn animals positively.

Introduction Teaching of congenital heart disease (CHD) through 3D printed models is feasible and useful as it improves learning. Medical students are highly satisfied with single defect CHD learning through 3D printing. Aim To evaluate the usefulness and degree of satisfaction with learning through 3D printed models in CHD with several associated defects, compared to a single defect CHD. Methods Students from 5th year of medicine attending a lecture in CoA (n = 118), VSD (n = 50) and TOF (n = 62) were randomised in 6 groups. During the lecture, 3D printed models of each CHD were presented and analysed by the students in the test group, same lecture without 3D models was performed for the control group for each CHD. Knowledge acquisition was obtained by pre and post-lecture test. Student's satisfaction and self-efficacy ratings were evaluated by the subjective post-lecture survey. Satisfaction between CHD groups was compared using Bonferroni method and test results between 3D & control group by t-test. Results Students in the multiple defect (ToF) group were less satisfied of 3D printed models than the students in the single defect (CoA & VSD) groups (P ˂ 0.01). After-lecture test scores for the groups attending the single defect CHD lectures were significantly higher for the students learning through 3D printed models (P = .04 in CoA group; P = 0.03 in VSD group). There was no difference in the post-lecture scores between the 3D learning and control groups attending the ToF lecture. Control ant test groups were comparable by age and sex ( Fig. 1 ). Conclusions Learning of complex CHD is challenging even with the most advanced educational techniques. Visual access to all the defects presented by the 3D model is necessary for correct understanding of the model. Transparent printing materials allow for the students to simulate the flow trajects with probes. In our experience, virtual 3D models can be a great resource and even more when analysed on virtual reality devices.

Aim: The aim of this study was to comparatively evaluate stability changes in palatal implants during the early stages of bone healing with chemically modified sandblasted/acid-etched (modSLA) titanium surface compared with a standard sandblasted (SLA) titanium palatal implants. Materials and Methods: A statistically significant number (n = 40; 24 females and 16 males) of adult subjects who volunteered and have their informed consent for participating in the study were selected. These volunteers were randomly allocated to the experimental group (modSLA surface) and to the control group (SLA surface) with 20 subjects in each group. Documentation of implant stability was done by assessing resonance frequency analysis (RFA) at implant insertion, followed by subsequent assessments each week till 12th week from baseline (1–12 weeks). RFA values were expressed as an implant stability quotient (ISQ). Results: Immediately after installation of implant, the ISQ values for both surfaces tested were not significantly different and yielded mean values of 75.28 ± 5.23 for the control and 73.16 ± 4.81 for the test surface. In the first 2 weeks after implant installation, both groups presented only small changes and thereafter a reducing trend in the mean ISQ levels. In the test group, after 4 weeks a tendency toward increasing ISQ values was observed, and 6 weeks after surgery the ISQ values corresponded to those after implant insertion. For the SLA control group, the trend changed after fifth week and yielded ISQ values corresponding to the baseline after ninth week. After 12 weeks of observation, the test surface yielded significantly higher stability values of 78.68 ± 2.9 compared with the control implants of 75.5 ± 3.19, respectively. Conclusion: The results undoubtedly support and validate the potential for chemical modification of the SLA surface to positively influence the biologic process of osseointegration and also a faster healing.

Background: Recent trends suggest using novel host-modulating agents as a treatment strategy for chronic periodontitis. Glucosamine sulfate (GS) was proven to have anti-inflammatory actions related to its ability to suppress neutrophil functions. Orthoboon, an anti-arthritic and anti-inflammatory drug, has shown to have a positive therapeutic effect due to its constituents made of a combination of GS, Vitamin C, and collagen. The aim of the study was to evaluate the host modulatory effects of Orthoboon on periodontal status and to estimate the C reactive protein (CRP) levels before and after nonsurgical periodontal therapy (NSPT). Materials and Methods: A total number of 40 patients with chronic periodontitis were randomly divided into two groups of 20 patients each. The test group patients (n = 20) received 500 mg Orthoboon three times daily for 45 days. Prior to the initiation of Orthoboon, all patients in both test group and control group were subjected to Phase I periodontal therapy. CRP levels were estimated immediately after phase I therapy and 45 days after therapy. Clinical parameters including plaque index, gingival index, and bleeding index were recorded before and after NSPT for the two groups. Results: The mean CRP levels were reduced significantly in the test group before and after administration of Orthoboon and also there were statistically significant differences in the mean CRP levels at the end of 45 days between the test group and the control group. Conclusion: Administration of Orthoboon, i.e., GS, with a combination of Vitamin C and collagen was proved to be of a significant benefit in the test group than in the control group.

Taking mixed lawn of Festuca elata Keng ex E. Alexeev and Poa pratensis L. as the research object, through the comparison of the electric heating, covering by non-woven fabric or electric heating and non-woven fabric treatment group with the control group, exploring the effects of winter temperature increase on prolonging the green period of lawn. The results show that: compared with the control group, different temperature increasing measures have different effects on prolonging the green period of the lawn. The test group using only electric heating or only covering the non-woven fabric was completely yellow in mid-January, which was about 10 days longer than the green period of the control group. The effect of using electric heating and non-woven fabric was the best. During the research period, the lawn of this group did not appear completely yellow. Compared with the control group, the green period was prolonged by about 53 days.

Aims: The aim of the study was to evaluate and compare physical properties such as tensile strength and tear strength of three commonly used silicone maxillofacial materials in Indian climatic condition. Settings and Design: An in vitro study was conducted to compare the tensile and tear strength using a universal testing machine with 100 N load at a speed of 20 mm/min. Specimens were prepared from three commercially available silicones, i.e., medical grade silicone (control group), prosthetic grade silicone (test Group 1), and a locally available medical grade silicone (test Group 2). One-way analysis of variance was carried out to test any significant difference between the mean values of tensile and tear strength between the tested materials. Post hoc test of Tukey was used to find which of the two groups' means shows a significant difference. Results: Prosthetic grade silicone showed the highest tensile strength with a P

Objective: To explore the clinical effect of applying Naomaitong in the treatment of cerebrovascular diseases. Method: The research work was carried out in our hospital from November 2018 to November 2019. A total of 100 patients were selected in this study, all of whom were cerebrovascular disease patients, and they were divided into two groups on average. Naofukang injection was named as the control group, and the other group was given Naofukang injection combined with Naomaitong oral liquid, and the therapeutic effects of the two groups were compared and analyzed. Results: The treatment efficiency of the patients in the test group and the control group were 94.00% and 82.00%, respectively. The effectiveness in the test group was higher. The difference in FIB and PagT levels between the two groups before treatment was small, P>0.05, which was non-significant. After the intervention, the FIB and PagT levels in the test group were lower, and the improvement effect was more significant. The difference between the two groups was PConclusion: The application of Naomaitong therapy in the treatment of cerebrovascular diseases has a significant effect. It can reduce the incidence of adverse reactions in patients and improve the clinical symptoms of patients, which has a positive significance for clinical development.

Objective: To apply Yiqi Naoluo Tong Decoction for clinical treatment of patients with cerebral infarction, and analyze the therapeutic effect of this method. Methods: 150 cases of cerebral infarction patients who were treated in our hospital were set as the research objects and divided into two groups. The conventional treatment methods were combined with Yiqi Naoluo Tong Decoction and single conventional treatment. Results: After treatment, the improvement of the test group of patients was better than that of the control group, and compared with the control group, the comparison result showed that P Conclusion: The addition of Yiqi Naoluo Tong Decoction in the clinical treatment of patients with cerebral infarction can improve the patients’ neurological deficits, quality of life, limb motor function and ability of daily living. This shows that this medicine has a higher clinical application value.