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517 results on '"leukocoria"'

501. Mobilní aplikace pro rozpoznání leukokorie ze snímku lidského obličeje

Author

Herout, Adam, Kodym, Oldřich, Hřebíček, Pavel, Herout, Adam, Kodym, Oldřich, and Hřebíček, Pavel

Abstract

Cílem této práce je návrh a implementace multiplatformní multijazyčné mobilní aplikace pro rozpoznání leukokorie ze snímku lidského obličeje pro platformy iOS a Android. Leukokorie je bělavý svit zornice, který se při použití blesku může na fotografii objevit. Včasnou detekcí tohoto symptomu lze zachránit zrak člověka. Samotná aplikace umožňuje analyzovat fotografii uživatele a detekovat přítomnost leukokorie. Cílem aplikace je tedy analýza očí člověka, od čehož je také odvozen název mobilní aplikace - Eye Check. K vytvoření multiplatformní mobilní aplikace byl použit framework React Native. Pro detekci lidského obličeje a očí byla zvolena knihovna Dlib, pro práci s fotografií pak knihovna OpenCV. Ke klasifikaci očí na případný výskyt leukokorie byla použita konvoluční neuronová síť. Komunikace mezi klientem a serverem je řešena pomocí architektury REST. Výsledkem je mobilní aplikace, která v případě detekce leukokorie uživatele upozorní, že by měl navštívit svého lékaře., The goal of this thesis is to design and implement a multiplatform multilingual mobile application for detecting leukocoria in an image of human face for iOS and Android platforms. Leukocoria is a whitish light of the pupil, which can be seen on the photo when the flash is used. Early detection of this symptom can save human eyesight. The application itself allows to analyze a user's photo and detect the presence of leukocoria. The goal of the application is to analyze eyes of the human, from which the mobile application name - Eye Check is derived. React Native framework was used to create a multiplatform mobile application. The Dlib library was chosen for human face and eye detection, the OpenCV library for working with the photo. The convolutional neural network was used to classify the eyes for the possible presence of leukocoria. Client-Server communication is solved using the REST architecture. The result is a mobile application that detects leukocoria and allerts the user to visit his doctor if leukocoria is detected.

502. Mobilní aplikace pro rozpoznání leukokorie ze snímku lidského obličeje

Author

Herout, Adam, Kodym, Oldřich, Herout, Adam, and Kodym, Oldřich

Abstract

Cílem této práce je návrh a implementace multiplatformní multijazyčné mobilní aplikace pro rozpoznání leukokorie ze snímku lidského obličeje pro platformy iOS a Android. Leukokorie je bělavý svit zornice, který se při použití blesku může na fotografii objevit. Včasnou detekcí tohoto symptomu lze zachránit zrak člověka. Samotná aplikace umožňuje analyzovat fotografii uživatele a detekovat přítomnost leukokorie. Cílem aplikace je tedy analýza očí člověka, od čehož je také odvozen název mobilní aplikace - Eye Check. K vytvoření multiplatformní mobilní aplikace byl použit framework React Native. Pro detekci lidského obličeje a očí byla zvolena knihovna Dlib, pro práci s fotografií pak knihovna OpenCV. Ke klasifikaci očí na případný výskyt leukokorie byla použita konvoluční neuronová síť. Komunikace mezi klientem a serverem je řešena pomocí architektury REST. Výsledkem je mobilní aplikace, která v případě detekce leukokorie uživatele upozorní, že by měl navštívit svého lékaře., The goal of this thesis is to design and implement a multiplatform multilingual mobile application for detecting leukocoria in an image of human face for iOS and Android platforms. Leukocoria is a whitish light of the pupil, which can be seen on the photo when the flash is used. Early detection of this symptom can save human eyesight. The application itself allows to analyze a user's photo and detect the presence of leukocoria. The goal of the application is to analyze eyes of the human, from which the mobile application name - Eye Check is derived. React Native framework was used to create a multiplatform mobile application. The Dlib library was chosen for human face and eye detection, the OpenCV library for working with the photo. The convolutional neural network was used to classify the eyes for the possible presence of leukocoria. Client-Server communication is solved using the REST architecture. The result is a mobile application that detects leukocoria and allerts the user to visit his doctor if leukocoria is detected.

503. Mobilní aplikace pro rozpoznání leukokorie ze snímku lidského obličeje

Author

Herout, Adam, Kodym, Oldřich, Herout, Adam, and Kodym, Oldřich

Abstract

Cílem této práce je návrh a implementace multiplatformní multijazyčné mobilní aplikace pro rozpoznání leukokorie ze snímku lidského obličeje pro platformy iOS a Android. Leukokorie je bělavý svit zornice, který se při použití blesku může na fotografii objevit. Včasnou detekcí tohoto symptomu lze zachránit zrak člověka. Samotná aplikace umožňuje analyzovat fotografii uživatele a detekovat přítomnost leukokorie. Cílem aplikace je tedy analýza očí člověka, od čehož je také odvozen název mobilní aplikace - Eye Check. K vytvoření multiplatformní mobilní aplikace byl použit framework React Native. Pro detekci lidského obličeje a očí byla zvolena knihovna Dlib, pro práci s fotografií pak knihovna OpenCV. Ke klasifikaci očí na případný výskyt leukokorie byla použita konvoluční neuronová síť. Komunikace mezi klientem a serverem je řešena pomocí architektury REST. Výsledkem je mobilní aplikace, která v případě detekce leukokorie uživatele upozorní, že by měl navštívit svého lékaře., The goal of this thesis is to design and implement a multiplatform multilingual mobile application for detecting leukocoria in an image of human face for iOS and Android platforms. Leukocoria is a whitish light of the pupil, which can be seen on the photo when the flash is used. Early detection of this symptom can save human eyesight. The application itself allows to analyze a user's photo and detect the presence of leukocoria. The goal of the application is to analyze eyes of the human, from which the mobile application name - Eye Check is derived. React Native framework was used to create a multiplatform mobile application. The Dlib library was chosen for human face and eye detection, the OpenCV library for working with the photo. The convolutional neural network was used to classify the eyes for the possible presence of leukocoria. Client-Server communication is solved using the REST architecture. The result is a mobile application that detects leukocoria and allerts the user to visit his doctor if leukocoria is detected.

504. Mobilní aplikace pro rozpoznání leukokorie ze snímku lidského obličeje

Author

Herout, Adam, Kodym, Oldřich, Herout, Adam, and Kodym, Oldřich

Abstract

Cílem této práce je návrh a implementace multiplatformní multijazyčné mobilní aplikace pro rozpoznání leukokorie ze snímku lidského obličeje pro platformy iOS a Android. Leukokorie je bělavý svit zornice, který se při použití blesku může na fotografii objevit. Včasnou detekcí tohoto symptomu lze zachránit zrak člověka. Samotná aplikace umožňuje analyzovat fotografii uživatele a detekovat přítomnost leukokorie. Cílem aplikace je tedy analýza očí člověka, od čehož je také odvozen název mobilní aplikace - Eye Check. K vytvoření multiplatformní mobilní aplikace byl použit framework React Native. Pro detekci lidského obličeje a očí byla zvolena knihovna Dlib, pro práci s fotografií pak knihovna OpenCV. Ke klasifikaci očí na případný výskyt leukokorie byla použita konvoluční neuronová síť. Komunikace mezi klientem a serverem je řešena pomocí architektury REST. Výsledkem je mobilní aplikace, která v případě detekce leukokorie uživatele upozorní, že by měl navštívit svého lékaře., The goal of this thesis is to design and implement a multiplatform multilingual mobile application for detecting leukocoria in an image of human face for iOS and Android platforms. Leukocoria is a whitish light of the pupil, which can be seen on the photo when the flash is used. Early detection of this symptom can save human eyesight. The application itself allows to analyze a user's photo and detect the presence of leukocoria. The goal of the application is to analyze eyes of the human, from which the mobile application name - Eye Check is derived. React Native framework was used to create a multiplatform mobile application. The Dlib library was chosen for human face and eye detection, the OpenCV library for working with the photo. The convolutional neural network was used to classify the eyes for the possible presence of leukocoria. Client-Server communication is solved using the REST architecture. The result is a mobile application that detects leukocoria and allerts the user to visit his doctor if leukocoria is detected.

505. Mobilní aplikace pro rozpoznání leukokorie ze snímku lidského obličeje

Author

Herout, Adam, Kodym, Oldřich, Hřebíček, Pavel, Herout, Adam, Kodym, Oldřich, and Hřebíček, Pavel

Abstract

Cílem této práce je návrh a implementace multiplatformní multijazyčné mobilní aplikace pro rozpoznání leukokorie ze snímku lidského obličeje pro platformy iOS a Android. Leukokorie je bělavý svit zornice, který se při použití blesku může na fotografii objevit. Včasnou detekcí tohoto symptomu lze zachránit zrak člověka. Samotná aplikace umožňuje analyzovat fotografii uživatele a detekovat přítomnost leukokorie. Cílem aplikace je tedy analýza očí člověka, od čehož je také odvozen název mobilní aplikace - Eye Check. K vytvoření multiplatformní mobilní aplikace byl použit framework React Native. Pro detekci lidského obličeje a očí byla zvolena knihovna Dlib, pro práci s fotografií pak knihovna OpenCV. Ke klasifikaci očí na případný výskyt leukokorie byla použita konvoluční neuronová síť. Komunikace mezi klientem a serverem je řešena pomocí architektury REST. Výsledkem je mobilní aplikace, která v případě detekce leukokorie uživatele upozorní, že by měl navštívit svého lékaře., The goal of this thesis is to design and implement a multiplatform multilingual mobile application for detecting leukocoria in an image of human face for iOS and Android platforms. Leukocoria is a whitish light of the pupil, which can be seen on the photo when the flash is used. Early detection of this symptom can save human eyesight. The application itself allows to analyze a user's photo and detect the presence of leukocoria. The goal of the application is to analyze eyes of the human, from which the mobile application name - Eye Check is derived. React Native framework was used to create a multiplatform mobile application. The Dlib library was chosen for human face and eye detection, the OpenCV library for working with the photo. The convolutional neural network was used to classify the eyes for the possible presence of leukocoria. Client-Server communication is solved using the REST architecture. The result is a mobile application that detects leukocoria and allerts the user to visit his doctor if leukocoria is detected.

506. Ocular toxocariasis presenting as leukocoria in a patient with low ELISA titer to Toxocara canis

Author

Leonard C. Marcus, Steven S. Searl, Daniel M. Albert, and Kambiz Moazed

Subjects
Pathology, medicine.medical_specialty, genetic structures, Eye Diseases, Leukocoria, Physical examination, Enzyme-Linked Immunosorbent Assay, Eye neoplasm, Diagnosis, Differential, Ophthalmology, medicine, Humans, Antigens, Toxocara, Ascariasis, Toxocariasis, biology, medicine.diagnostic_test, Retinoblastoma, business.industry, Eye Neoplasms, biology.organism_classification, medicine.disease, eye diseases, Canis, Child, Preschool, Female, medicine.symptom, Differential diagnosis, business, Toxocara canis
Abstract

A 4-year-old white female presented with leukocoria of the right eye. White punctate lesions were observed posterior to the retrolental membrane, which suggested retinoblastoma of some examiners. A full history, physical examination, ultrasonography, and CT scan failed to rule the diagnosis of retinoblastoma in or out. A serum ELISA titer was 1:4, which was considered nondiagnostic. Examination of the enucleated eye revealed a midsegment of the second stage larva of Toxocara canis. The strengths and weaknesses of various diagnostic modalities used to differentiate leukocoria caused by retinoblastoma and T canis are discussed.

Published
1981

507. Ancillary diagnostic testing in the differentiation of retinoblastoma and advanced Coats’ disease

Author

Robert M. Ellsworth, Barrett G. Haik, Mary E. Smith, and L. Saint Louis

Subjects
medicine.medical_specialty, medicine.diagnostic_test, Retinoblastoma, business.industry, Leukocoria, Retinal detachment, Diagnostic test, Magnetic resonance imaging, Disease, medicine.disease, eye diseases, Ophthalmology, Pupillary reflex, medicine, Coats' disease, medicine.symptom, business
Abstract

Leukocoria is an important clinical sign in ophthalmology characterized by a white pupillary reflex resulting from an intraocular mass or retrolental opacity. Although a number of developmental, inflammatory, neoplastic, and hemorrhagic conditions can result in this clinical sign, the most important condition in which it occurs is retinoblastoma. Retinoblastoma is a primary malignant retinal tumor that if left untreated will eventually lead to destruction of the globe followed by extraocular spread with resultant mortality. Its diagnosis and differentiation from other leukocoria conditions is important in order to permit appropriate specific therapy. Many clinical findings are helpful in delineating the cause of leukocoria and in differentiating retinoblastoma from simulating conditions. However, in other cases, diagnosis cannot be established on purely ophthalmoscopic grounds. Advanced Coats’ disease is a condition characterized by congenital retinal telangiectasias with associated massive subretinal exudation and retinal detachment that can closely mimic the clinical appearance of retinoblastoma. We have found that certain ancillary diagnostic tests are helpful in establishing a secure diagnosis. The synergistic use of ultrasonography, computerized tomography and magnetic resonance imaging has aided in this important clinical distinction.

Published
1987

508. Unusual case of acute orbital cellulitis

Author

G Frank Judisch and David E Braverman

Subjects
medicine.medical_specialty, genetic structures, Eye Diseases, Leukocoria, Enucleation, Diagnosis, Differential, Uveitis, Ophthalmology, Medicine, Humans, Unusual case, business.industry, Retinal Detachment, Retinal detachment, Infant, Panophthalmitis, Cellulitis, General Medicine, medicine.disease, eye diseases, Child, Preschool, Pediatrics, Perinatology and Child Health, Etiology, Female, sense organs, Differential diagnosis, medicine.symptom, Orbital cellulitis, business, Orbit
Abstract

A three and one-half year-old female who presented with orbital cellulitis and leukocoria is described. Enucleation was performed as the eye was microophthalmic, blind, and painful. Histopathologic study revealed uveitis with total retinal detachment. The etiology of the retinal detachment was indeterminable. The differential diagnosis of orbital cellulitis in children is reviewed.

Published
1978

509. Ultrasonic Diagnosis of Intraocular Cysticercus

Author

Eduardo Moragrega

Subjects
medicine.medical_specialty, business.industry, Retinoblastoma, Leukocoria, Retinal detachment, Cysticercosis, Cysticercus, medicine.disease, eye diseases, Severe inflammation, Ophthalmology, Ophthalmic artery, medicine.artery, medicine, medicine.symptom, business, Uveitis
Abstract

A, B and D scan echographic studies were performed on 17 patients who had previously been diagnosed ophthalmoscopic ally as having intraocular cysticercosis and on 8 patients who were diagnosed on the basis of these echographic studies. The 8 last patients had severe inflammation, retinal detachment and one probably a retinoblastoma. The echographic diagnosis were corroborated by surgery after anti-inflammatory-treatment. We believe that in our environment, intraocular cysticercosis should be ruled out when uveitis is present in an adult and when leukocoria is present. This is the first report of a 25 patient series with intraocular Cysticercus studied and diagnosed with A and B-scan simultaneously.

Published
1983

510. Persistent hyperplastic primary vitreous in the right eye and congenital grouped pigmentation of the retina in the left

Author

Seiji Hayasaka, Masimitsu Fujii, and Tomoichi Setogawa

Subjects
Male, genetic structures, Leukocoria, Eye disease, Visual Acuity, Cataract, Retinal Diseases, medicine, Electroretinography, Humans, Eye Abnormalities, Fluorescein Angiography, Ultrasonography, Retina, medicine.diagnostic_test, business.industry, Infant, General Medicine, Anatomy, medicine.disease, Fluorescein angiography, eye diseases, Sensory Systems, Microcornea, Vitreous Body, Ophthalmology, medicine.anatomical_structure, Persistent hyperplastic primary vitreous, Falciform retinal fold, sense organs, medicine.symptom, business, Pigmentation Disorders
Abstract

We have recently treated an 8-year-old boy who had leukocoria, microcornea, cataract, and falciform retinal fold in the right eye and multiple grouped patches of pigmentation in the left retina. These were diagnosed as persistent hyperplastic primary vitreous in the right eye and congenital grouped pigmentation of the retina in the left. This patient had a different rare congenital anomaly in each eye.

Published
1989

511. Magnetic resonance imaging versus computed tomography of leukocoric eyes and use of in vitro proton magnetic resonance spectroscopy of retinoblastoma

Author

Bahram Raofi, Efstathios D. Gotsis, Marc J. Safran, Steven B. Cohen, Mahmood F. Mafee, Lavanya Chekuri, and Morton F. Goldberg

Subjects
Uveal Neoplasms, Magnetic Resonance Spectroscopy, Adolescent, Eye Diseases, Eye disease, Leukocoria, Medicine, Humans, Child, Melanoma, medicine.diagnostic_test, business.industry, Retinoblastoma, Eye Neoplasms, Contrast resolution, Calcinosis, Infant, Magnetic resonance imaging, medicine.disease, Magnetic Resonance Imaging, eye diseases, Ophthalmology, Persistent hyperplastic primary vitreous, Child, Preschool, sense organs, medicine.symptom, business, Nuclear medicine, Tomography, X-Ray Computed, Calcification
Abstract

To evaluate the usefulness of magnetic resonance imaging (MRI) in the evaluation of leukocoric eyes, the authors studied 28 patients with either leukocoria or intraocular mass with a 1.5-tesla (T) MRI imager. Retinoblastomas were reliably distinguished from Coats' disease, toxocariasis, and persistent hyperplastic primary vitreous on the basis of MRI findings. Calcification cannot be reliably detected on MRI scans. Lesions elevated less than 4 mm may not be detected reliably by MRI at this time. Computed tomography (CT) can detect calcification with a high degree of accuracy. Retinoblastomas appeared as moderately hyperintense masses on T1- and proton-weighted MRIs. They became hypointense in T2-weighted MRIs. This MRI characteristic is similar to that of uveal melanoma. Intraocular calcification in children especially younger than 3 years of age is highly suggestive of retinoblastoma. In the diagnosis of retinoblastoma, MRI is not as specific as CT because of its lack of sensitivity in detecting calcification. However, MRI, because of its superior contrast resolution, offers more information in the differentiation of pathologic intraocular conditions responsible for leukocoria. The authors also describe their preliminary work of in vitro proton magnetic resonance spectroscopy of eyes with retinoblastoma and an eye with uveal melanoma in an 18-year-old black woman.

Published
1989

512. Persistent hyperplastic primary vitreous. A clinicopathologic study of 62 cases and review of the literature

Author

Ramon L. Font, Frederick Reeser, and Raja Haddad

Subjects
Male, Pathology, medicine.medical_specialty, Trisomy 13 Syndrome, genetic structures, Adolescent, Leukocoria, Ophthalmologic Surgical Procedures, Microphthalmia, Cataract, Ophthalmology, medicine, Animals, Humans, Microphthalmos, Eye Abnormalities, Persistent fetal vasculature, Hyperplasia, business.industry, Eye Neoplasms, Infant, Newborn, Retinal Detachment, Retinal detachment, Infant, Glaucoma, medicine.disease, eye diseases, Vitreous Body, Persistent hyperplastic primary vitreous, Retinal dysplasia, Female, sense organs, Phthisis bulbi, medicine.symptom, business
Abstract

This is a clinicopathologic study of 62 cases of persistent hyperplastic primary vitreous (PHPV). The cases were divided into two main groups. Group 1 consisted of 55 unilateral cases not associated with any systemic abnormalities, including 36 eyes (58%) which were considered "pure cases" (Group 1A) and 19 (31%) which disclosed other ocular abnormalities in addition to PHPV (Group 1B). Group 2 consisted of 7 (11%) bilateral cases of PHPV accompanied by other ocular and systemic malformations. The most common presenting clinical signs are leukocoria, microphthalmia and cataract. The main histopathologic features of this condition are outlined, including those responsible for the disastrous results to the eye (retinal detachment, glaucoma, phthisis bulbi). Several clinical entities, usually mistaken for or associated with PHPV, such as retinoblastoma, congenital cataract, retinal dysplasia, trisomy 13 syndrome, and falciform retinal folds are discussed briefly.

Published
1978

513. Retinal detachment in the morning glory anomaly

Author

Barrett G. Haik, Mary E. Smith, Robert M. Ellsworth, David H. Abramson, and Scott H. Greenstein

Subjects
Adult, Male, medicine.medical_specialty, Morning glory disc anomaly, Adolescent, Leukocoria, Morning glory anomaly, Amblyopia, chemistry.chemical_compound, Cerebrospinal fluid, Ophthalmology, Electroretinography, Medicine, Humans, Eye Abnormalities, Child, Ultrasonography, business.industry, Infant, Newborn, Retinal Detachment, Retinal detachment, Infant, Retinal Vessels, Retinal, Optic Nerve, medicine.disease, Surgery, Coloboma, medicine.anatomical_structure, chemistry, Child, Preschool, Optic nerve, Evoked Potentials, Visual, Female, Subarachnoid space, medicine.symptom, business, Tomography, X-Ray Computed, Follow-Up Studies
Abstract

The morning glory anomaly is a rare congenital clinical entity that results from abnormal optic nerve development. In our series of 30 patients, followed for a mean duration of 10.3 years, 11 developed associated retinal detachments. These detachments followed a variable clinical course, including spontaneous reattachment and even redetachment, and may result from an abnormal communication between the subarachnoid space of the optic nerve and the subretinal space, allowing cerebrospinal fluid to accumulate subretinally. The clinical findings (including ultrasonography, computed tomography, and electrophysiologic testing), natural history, complications, and therapeutic indications are discussed.

Published
1984

514. Congenital glaucoma and retinal dysplasia

Author

Z N Zakov, G R Beauchamp, and M W Preslan

Subjects
Male, Polychlorinated Dibenzodioxins, genetic structures, Eye disease, Leukocoria, Glaucoma, Retina, Agent Orange, Medicine, Humans, Abnormalities, Multiple, Iris (anatomy), Intraocular hemorrhage, business.industry, 2,4,5-Trichlorophenoxyacetic Acid, Abnormalities, Drug-Induced, Infant, General Medicine, Anatomy, medicine.disease, eye diseases, Ophthalmology, medicine.anatomical_structure, Dysplasia, Pediatrics, Perinatology and Child Health, Retinal dysplasia, sense organs, Trabecular meshwork, medicine.symptom, 2,4-Dichlorophenoxyacetic Acid, business
Abstract

The differential diagnosis of leukocoria (pseudoglioma) in the neonate includes multiple conditions, including malformations with retinal dysplasia as a component. Typically bilateral, retinal dysplasia is characteristically seen in microphthalmic eyes. Certain chromosomal defects have been described. The case reported herein presented in the first month of life with an enlarged eye, elevated intraocular pressure, prominent iris vasculature, and leukocoria. Family history was positive in one respect: this is the second child of a Viet Nam veteran exposed to Agent Orange. The first child, from a different mother, also had birth defects. Other than his left eye, the child is completely normal. Ultrasonography showed posterior vitreous opacities of indeterminate configuration. CT scan suggested a posterior intraocular mass. Histologically, the principal features were an anomalous, largely unformed corneoscleral angle, intraocular hemorrhage, and retinal dysplasia. Light microscopic studies were performed. The corneoscleral angle revealed an anteriorly inserted iris with an absence of trabecular meshwork and Schlemm's canal. This case is considered unique on the basis of the association of retinal dysplasia with congenital glaucoma and larger-than-normal eye. The significance of reported paternal exposure to Agent Orange in this instance is unknown.

Published
1985

515. Detection of leukocoria using a soft fusion of expert classifiers under non-clinical settings

Author

Greg Hamerly, Bryan F. Shaw, Erich J. Baker, and Pablo Rivas-Perea

Subjects
Leukocoria, Fuzzy logic, Pattern Recognition, Automated, Pupil Disorders, Discrete cosine transform, Photography, Medicine, Preprocessor, Humans, Karhunen-Loeve transform, Karhunen–Loève theorem, Soft computing, business.industry, Retinoblastoma, Reproducibility of Results, Pattern recognition, General Medicine, Ophthalmology, Technical Advance, Pattern recognition (psychology), Artificial intelligence, False positive rate, medicine.symptom, business, Algorithms
Abstract

Background Leukocoria is defined as a white reflection and its manifestation is symptomatic of several ocular pathologies, including retinoblastoma (Rb). Early detection of recurrent leukocoria is critical for improved patient outcomes and can be accomplished via the examination of recreational photography. To date, there exists a paucity of methods to automate leukocoria detection within such a dataset. Methods This research explores a novel classification scheme that uses fuzzy logic theory to combine a number of classifiers that are experts in performing multichannel detection of leukocoria from recreational photography. The proposed scheme extracts features aided by the discrete cosine transform and the Karhunen-Loeve transformation. Results The soft fusion of classifiers is significantly better than other methods of combining classifiers with p = 1.12 × 10-5. The proposed methodology performs at a 92% accuracy rate, with an 89% true positive rate, and an 11% false positive rate. Furthermore, the results produced by our methodology exhibit the lowest average variance. Conclusions The proposed methodology overcomes non-ideal conditions of image acquisition, presenting a competent approach for the detection of leukocoria. Results suggest that recreational photography can be used in combination with the fusion of individual experts in multichannel classification and preprocessing tools such as the discrete cosine transform and the Karhunen-Loeve transformation. Electronic supplementary material The online version of this article (doi:10.1186/1471-2415-14-110) contains supplementary material, which is available to authorized users.

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516. Leukocoria: Clinical and Neuroradiological Findings

Author

T. Hadijstilianou, C. Venturi, and Paolo Galluzzi

Subjects
medicine.medical_specialty, Radiological and Ultrasound Technology, Retinoblastoma, business.industry, Leukocoria, medicine.disease, eye diseases, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Pupillary reflex, Ophthalmology, 030221 ophthalmology & optometry, medicine, Radiology, Nuclear Medicine and imaging, Neurology (clinical), medicine.symptom, Abnormality, business
Abstract

Leukocoria is a whitish pupillary reflex resulting from retrolental abnormality. Leukocoria presents in childhood, and is an important alerting sign of intraocular pathology. In particular, leukocoria is the most common presenting sign of retinoblastoma. Neuroradiological examinations may help in the differential diagnosis between retinoblastoma and simulating lesions, such as persistent hyperplastic primary vitreous, Coat's disease, retinopathy of prematurity, etc. Close interdisciplinary collaboration between neuroradiologist and ophthalmologist is essential to provide accurate early diagnosis and proper treatment.

517. Ocular Trauma Following Amniocentesis as the Cause of Leukocoria

Author

D BenEzra and M M Admoni

Subjects
Adult, medicine.medical_specialty, genetic structures, Leukocoria, Perforation (oil well), Diagnostic amniocentesis, Ocular trauma, Reflex, Pupillary, Conjunctival Diseases, Eye Injuries, Pregnancy, medicine, Humans, medicine.diagnostic_test, Cysts, business.industry, Infant, Newborn, Retinal Detachment, Pupil, General Medicine, Traction retinal detachment, eye diseases, Surgery, Ophthalmology, Left eye, Iris Diseases, Pediatrics, Perinatology and Child Health, Amniocentesis, Female, sense organs, medicine.symptom, business
Abstract

Among the various causes of leukocoria in a newborn, intrauterine ocular trauma following amniocentesis Is not included. We describe a three-day-old girl whose leukocoria ol the left eye resulted from traction retinal detachment, caused by the perforation of the globe during diagnostic amniocentesis.

Published
1988

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