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Plasma measurements by electrostatic probes are influenced by the spacecraft-plasma interaction, including the photoelectrons emitted by the spacecraft. Such effects get particularly important in tenuous plasmas with large Debye lengths. We have used the particle-in-cell code package SPIS to study the close environment of the Rosetta spacecraft, and the impact of the spacecraft-plasma interaction on the electrostatic potential at the position of the Langmuir probes onboard. The simulations show that in the solar wind, photoemission has a bigger impact than wake formation. Spacecraft potential estimates based on Langmuir probe data in the solar wind need to be compensated for these effects when the spacecraft attitude varies. The SPIS simulations are validated by comparison to an independent code.

Ions apparently emanating from the same source, the ionospheric polar cap, can either end up as energized to keV energies in the high-altitude cusp/mantle, or appear as cold ions in the magnetotail lobes. We use Cluster observations of ions and wave electric fields to study the spatial variation of ion heating in the cusp/mantle and polar cap. The average flow direction in a simplified cylindrical coordinate system is used to show approximate average ion flight trajectories, and discuss the temperatures, fluxes and wave activity along some typical trajectories. It is found that it is suitable to distinguish between cusp, central and nightside polar cap ion outflow trajectories, though O + heating is mainly a function of altitude. Furthermore we use typical cold ion parallel velocities and the observed average perpendicular drift to obtain average cold ion flight trajectories. The data show that the cusp is the main source of oxygen ion outflow, whereas a polar cap source would be consistent with our average outflow paths for cold ions observed in the lobes. A majority of the cusp O + flux is sufficiently accelerated to escape into interplanetary space. A scenario with significant oxygen ion heating in regions with strong magnetosheath origin ion fluxes, cold proton plasma dominating at altitudes below about 8 R E in the polar cap, and most of the cusp oxygen outflow overcoming gravity and flowing out in the cusp and mantle is consistent with our observations.

Abstract Available from http://www.agu.org

Background:Understanding the protective potential of operating room (OR) ventilation under different conditions is crucial to optimizing the surgical environment. This study investigated the air quality, expressed as colony-forming units (CFU)/m³, during orthopedic trauma surgery in a displacementventilated OR; explored how traffic flow and the number of persons present in the OR affects the air contamination rate in the vicinity of surgical wounds; and identified reasons for door openings in the OR. Methods:Data collection, consisting of active air sampling and observations, was performed during 30 orthopedic procedures. Results:In 52 of the 91 air samples collected (57%), the CFU/m³ values exceeded the recommended level of <10 CFU/m³. In addition, the data showed a strongly positive correlation between the total CFU/m³ per operation and total traffic flow per operation (r=0.74;P=.001; n=24), after controlling for duration of surgery. A weaker, yet still positive correlation between CFU/m³ and the number of persons present in the OR (r=0.22;P=.04; n=82) was also found. Traffic flow, number of persons present, and duration of surgery explained 68% of the variance in total CFU/m³ (P=.001). Conclusions:Traffic flow has a strong negative impact on the OR environment. The results of this study support interventions aimed at preventing surgical site infections by reducing traffic flow in the OR.

In critically ill patients, mechanisms underlying diaphragm muscle remodeling and resultant dysfunction contributing to weaning failure remain unclear. Ventilator-induced modifications as well as sepsis and administration of pharmacological agents such as corticosteroids and neuromuscular blocking agents may be involved. Thus, the objective of the present study was to examine how sepsis, systemic corticosteroid treatment (CS) and neuromuscular blocking agent administration (NMBA) aggravate ventilator-related diaphragm cell and molecular dysfunction in the intensive care unit. Piglets were exposed to different combinations of mechanical ventilation and sedation, endotoxin-induced sepsis, CS and NMBA for five days and compared with sham-operated control animals. On day 5, diaphragm muscle fibre structure (myosin heavy chain isoform proportion, cross-sectional area and contractile protein content) did not differ from controls in any of the mechanically ventilated animals. However, a decrease in single fibre maximal force normalized to cross-sectional area (specific force) was observed in all experimental piglets. Therefore, exposure to mechanical ventilation and sedation for five days has a key negative impact on diaphragm contractile function despite a preservation of muscle structure. Post-translational modifications of contractile proteins are forwarded as one probable underlying mechanism. Unexpectedly, sepsis, CS or NMBA have no significant additive effects, suggesting that mechanical ventilation and sedation are the triggering factors leading to diaphragm weakness in the intensive care unit.

The basic mechanisms underlying acquired generalized muscle weakness and paralysis in critically ill patients remain poorly understood and may be related to prolonged mechanical ventilation/immobilization (MV) or to other triggering factors such as sepsis, systemic corticosteroid (CS) treatment and administration of neuromuscular blocking agents (NMBA). The present study aims at exploring the relative importance of these factors by using a unique porcine model. Piglets were all exposed to MV together with different combinations of endotoxin-induced sepsis, CS and NMBA for five days. Peroneal motor nerve conduction velocity and amplitude of the compound muscle action potential (CMAP) as well as biceps femoris muscle biopsy specimens were obtained immediately after anesthesia on the first day and at the end of the 5-day experimental period. Results showed that peroneal nerve motor conduction velocity is unaffected whereas the size of the CMAP decreases independently of the type of intervention, in all groups after 5 days. Otherwise, despite a preserved size, muscle fibre specific force (maximum force normalized to cross-sectional area) decreased dramatically for animals exposed to MV in combination with CS or/and sepsis. These results suggest that the rapid declines in CMAP amplitude and in force generation capacity are triggered by independent mechanisms with significant clinical and therapeutic implications.

We present in situ Cassini Radio Plasma Wave Science observations in the vicinity of Enceladus and in the E ring of Saturn that indicate the presence of dusty plasma. The four flybys of Enceladus in 2008 revealed the following cold plasma characteristics: (1) there is a large plasma density (both ions and electrons) within the Enceladus plume region, (2) no plasma wake effect behind Enceladus was detected, (3) electron densities are generally much lower than the ion densities in the E ring (n(e)/n(i) < 0.5) as well as in the plume (n(e)/n(i) < 0.01), and (4) the average bulk ion drift speed is significantly less than the corotation speed and is instead close to the Keplerian speed. These signatures result from half or more of the electrons being attached to dust grains and by the interaction between the surrounding cold plasma and the predominantly negatively charged submicrometer-sized dust grains. The dust and plasma properties estimated from the observations clearly show that the dust-plasma interaction is collective. This strong dust-plasma coupling appears not only in the Enceladus plume but also in the Enceladus torus, typically from about 20 R(E) (similar to 5000 km) north and about 60 R(E) (similar to 15,000 km) south of Enceladus. We also suggest that the dust-plasma interaction in the E ring is the cause of the planetary spin-modulated dynamics of Saturn's magnetosphere at large.

Acute quadriplegic myopathy (AQM) is a common debilitating acquired disorder in critically ill intensive care unit (ICU) patients which is characterized by tetraplegia/generalized weakness of limb and trunk muscles. Masticatory muscles, on the other hand, are typically spared or less affected, yet the mechanisms underlying this striking muscle-specific difference remain unknown. This study aims to evaluate physiological parameters and the gene expression profiles of masticatory and limb muscles exposed to factors suggested to trigger AQM, such as mechanical ventilation, immobilization, neuromuscular blocking agents (NMBA), corticosteroids (CS) and sepsis for five days by using a unique porcine model mimicking the ICU conditions. Single muscle fiber cross-sectional area and force-generating capacity, i.e., maximum force normalized to fiber cross-sectional area (specific force), revealed maintained masseter single muscle fiber cross-sectional area and specific-force after five days exposure to all triggering factors. This is in sharp contrast to observations in limb and trunk muscles, showing a dramatic decline in specific force in response to five days exposure to the triggering factors. Significant differences in gene expression were observed between craniofacial and limb muscles, indicating a highly complex and muscle specific response involving transcription and growth factors, heat shock proteins, matrix metalloproteinase inhibitor, oxidative stress responsive elements and sarcomeric proteins underlying the relative sparing of cranial versus spinal nerve innervated muscles during exposure to the ICU intervention.

In critically ill patients, ventilator-induced diaphragm muscle fibre dysfunction (VIDD) contributes to weaning problems, increasing hospitalisation time and related costs. VIDD pathophysiology remains partially unknown, especially the characterisation of the contractile dysfunction. In the present study, it was hypothesised that Ca(2+) activation is affected during VIDD. Ca(2+) sensitivity of contraction was therefore evaluated at the single skinned diaphragm muscle fibre level in piglets randomised into sham operation or 5-day mechanical ventilation. Ca(2+) sensitivities of force and stiffness in fibres were significantly impaired in all mechanically ventilated piglets compared with sham-operated controls, suggesting a less efficient Ca(2+) activation of cells, i.e. a lower relative number of strongly attached cross-bridges for each sub-maximal concentration of Ca(2+). In an attempt to test whether this negative effect of VIDD is reversible, single muscle fibres were exposed to the EMD 57033 Ca(2+) sensitiser. EMD 57033 (30 microM) improved the Ca(2+) sensitivity of force and stiffness in fibres from animals that were mechanically ventilated for 5 days as well as in sham-operated piglets. Thus, EMD 57033 partly restored the Ca(2+) activation of cells, reducing VIDD. This finding offers a strong basis for evaluating the effect of Ca(2+) sensitisers on diaphragm function in vivo.

BACKGROUND: Anticoagulant prophylaxis substantially reduces the risk of venous thromboembolism (VTE) after major orthopedic surgery. The direct factor Xa inhibitor YM150 is currently under investigation for the prevention of VTE, stroke and ischemic vascular events in patients after orthopedic surgery, with atrial fibrillation and with acute coronary syndrome, respectively. OBJECTIVES: To investigate the efficacy and safety of YM150 for the prevention of VTE following elective total hip arthroplasty. PATIENTS/METHODS: Patients were randomized to postoperative, once-daily, oral YM150 (5, 10, 30, 60 or 120 mg) (double-blind) or preoperative subcutaneous (open label) enoxaparin (40 mg) for 5 weeks. The primary efficacy endpoint comprised VTE diagnosed by mandatory bilateral venography or verified symptomatic deep vein thrombosis (DVT) plus all deaths up to 9 days after surgery. The primary safety outcome was major bleeding up to 9 days after surgery. RESULTS: Primary efficacy endpoint: of 1017 patients randomized, 960 patients were evaluable for safety and 729 patients for efficacy. A dose-related decrease in VTE incidence from YM150 5 to 60 mg (P = 0.0005) and from 5 to 120 mg (P = 0.0002) was found. The VTE incidence was 27.4%, 31.7%, 19.3%, 13.3% and 14.5% for 5, 10, 30, 60 and 120 mg YM150, respectively, and 18.9% for enoxaparin. Primary safety endpoint: there was one major bleed with YM150 (60 mg) and one with enoxaparin. CONCLUSIONS: The oral direct FXa inhibitor YM150 demonstrated a significant dose response regarding efficacy. Doses from 30 to 120 mg had comparable efficacy to enoxaparin, without compromising safety regarding major bleeding events.

We present several independent in-situ measurements, which provide evidence that charged dust in the E-ring interacts collectively with the dense surrounding plasma disk of Saturn, i.e., form a system of dust-plasma interaction. The results are based on data sampled by the Radio and Plasma Wave Science (RPWS) investigation onboard Cassini, which allows for interferometry of plasma density inhomogeneities (δn/n) with two antenna elements and a Langmuir probe sensor. The interferometer experiment detects two ion populations; one co-rotating with the planetary magnetic field and another moving with near Keplerian speed around Saturn. The full range of RPWS measurements indicates that the Keplerian population consists of colder ions (Ti

Skeletal muscle wasting and impaired muscle function in response to mechanical ventilation and immobilization in intensive care unit (ICU) patients are clinically challenging partly due to 1) the poorly understood intricate cellular and molecular networks and 2) the unavailability of an animal model mimicking this condition. By employing a unique porcine model mimicking the conditions in the ICU with long-term mechanical ventilation and immobilization, we have analyzed the expression profile of skeletal muscle biopsies taken at three time points during a 5-day period. Among the differentially regulated transcripts, extracellular matrix, energy metabolism, sarcomeric and LIM protein mRNA levels were downregulated, while ubiquitin proteasome system, cathepsins, oxidative stress responsive genes and heat shock proteins (HSP) mRNAs were upregulated. Despite 5 days of immobilization and mechanical ventilation single muscle fiber cross-sectional areas as well as the maximum force generating capacity at the single muscle fiber level were preserved. It is proposed that HSP induction in skeletal muscle is an inherent, primary, but temporary protective mechanism against protein degradation. To our knowledge, this is the first study that isolates the effect of immobilization and mechanical ventilation in an ICU condition from various other cofactors.

BACKGROUND: Ximelagatran, the first oral direct thrombin inhibitor, was shown to be an effective antithrombotic agent but was associated with potential liver toxicity after prolonged administration. OBJECTIVES AND METHODS: The aim of the EXTEND study was to assess safety and efficacy of extended administration (35 days) of ximelagatran or enoxaparin for the prevention of venous thromboembolism after elective hip replacement and hip fracture surgery. A follow-up period, including assessment of liver enzymes (in particular alanine aminotransferase; ALAT), until post-operative day 180 was planned, with visits at days 56 and 180. RESULTS: Randomization and administration of study drugs were stopped following a report of serious liver injury occurring 3 weeks after completion of ximelagatran treatment. At the time of study termination, 1158 patients had been randomized and 641 had completed the 35-day treatment; with 303 ximelagatran and 265 enoxaparin patients remaining in the study through to the day 56 follow-up visit. Overall, 58 patients showed an ALAT increase to >2x upper limit of normal: 31 treated with enoxaparin, 27 with ximelagatran. Three ximelagatran patients also showed symptoms potentially related to liver toxicity. Eleven ximelagatran patients showed an ALAT increase after study treatment ended. The clinical development of ximelagatran was terminated and the drug withdrawn from the market. Evaluation of the relative efficacy of the two treatments as specified in the protocol was impossible due to the premature termination of the study. CONCLUSIONS: Prolonged administration of ximelagatran was associated with an increased risk of liver toxicity. In a substantial proportion of patients, ALAT increase occurred after treatment withdrawal. The findings seen with ximelagatran should be considered when designing studies with new antithrombotic agents., On behalf of the EXTEND Study Group

Low-energy ions escape from the ionosphere and constitute a large part of the magnetospheric content, especially in the geomagnetic tail lobes. However, they are normally invisible to spacecraft measurements, since the potential of a sunlit spacecraft in a tenuous plasma in many cases exceeds the energy-per-charge of the ions, and little is therefore known about their outflow properties far from the Earth. Here we present an extensive statistical study of cold ion outflows (0-60 eV) in the geomagnetic tail at geocentric distances from 5 to 19 R-E using the Cluster spacecraft during the period from 2001 to 2005. Our results were obtained by a new method, relying on the detection of a wake behind the spacecraft. We show that the cold ions dominate in both flux and density in large regions of the magnetosphere. Most of the cold ions are found to escape from the Earth, which improves previous estimates of the global outflow. The local outflow in the magnetotail corresponds to a global outflow of the order of 10(26) ions s(-1). The size of the outflow depends on different solar and magnetic activity levels.

The dramatic muscle wasting, preferential loss of myosin and impaired muscle function in intensive care unit (ICU) patients with acute quadriplegic myopathy (AQM) have traditionally been suggested to be the result of proteolysis via specific proteolytic pathways. In this study we aim to investigate the mechanisms underlying the preferential loss of thick vs. thin filament proteins and the reassembly of the sarcomere during the recovery process in muscle samples from ICU patients with AQM. Quantitative and qualitative analyses of myofibrillar protein and mRNA expression were analyzed using SDS-PAGE, confocal microscopy, histochemistry and real-time PCR. The present results demonstrate that the transcriptional regulation of myofibrillar protein synthesis plays an important role in the loss of contractile proteins, as well as the recovery of protein levels during clinical improvement, myosin in particular, presumably in concert with proteolytic pathways, but the mechanisms are specific to the different thick and thin filament proteins studied.

We present observational evidence that the ionosphere of Titan below an altitude of 1150 km is a significant source of heavy (> 100 amu) molecular organic species. This study is based on measurements by five instruments (RPWS/LP, RPWS/E, INMS, CAPS/ELS, CAPS/IBS) onboard the Cassini spacecraft during three flybys (T17, T18, T32) of Titan. The ionospheric peaks encountered at altitudes of 950-1300 km had densities in the range 900-3000 cm(-3). Below these peaks the number densities of heavy positively charged ions reached 100-2000 cm(-3) and approached 50-70% of the total ionospheric density with an increasing trend toward lowest measured altitudes. Simultaneously measured negatively charged ion densities were in the range 50-150 cm(-3). These results imply that similar to 10(5)similar to 10(6) heavy positively charged ions/m(3)/s are continuously recombining into heavy neutrals and supply the atmosphere of Titan. The ionosphere may in this way produce 0.1-1 Mt/yr of heavy organic compounds and is therefore a sizable source for aerosol formation. We also predict that Titan's ionosphere is dominated by heavy (> 100 amu) molecular ions below 950 km.

We present the first two-spacecraft near-simultaneous observations of the Martian bow shock (BS), magnetic pileup boundary (MPB) and photo-electron boundary (PEB) obtained by the plasma instruments onboard Rosetta and Mars Express during the Rosetta Mars fly by on February 25, 2007. Our observations are compared with shape models for the BS and MPB derived from previous statistical studies. The MPB is found at its expected position but the BS for this event is found significantly closer to the planet than expected for the rather slow and moderately dense solar wind. Cross-calibration of the density measurements on the two spacecraft gives a density profile through the magnetosheath, indicating an increasing solar wind flux during the Rosetta passage which is consistent with the multiple BS crossings at the Rosetta exit.

The Earth constantly loses matter, mostly in the form of H+and O+ ions, through various outflow processes from the upper atmosphere and ionosphere. Most of these ions are cold (below 1 eV in thermal energy), but can still escape and travel farther out along the magnetic field lines into the magnetospheric tail lobes. The outflow has previously beenmeasured close to the Earth. To understand what fraction does not return but instead escapes, the measurements should be conducted at larger geocentric distances. However, at high altitudes the cold ions are normally invisible to spacecraft measurements, because the potential of a sunlit spacecraft exceeds the equivalent energy of the ions. Here we show that cold ions dominate in both flux and density in the distant magnetotail lobes, using a new measurement technique on the Cluster spacecraft. The total loss of cold hydrogen ions from the planet is inferred to be of the order of 1026 s−1, which is larger than the previously observed more energetic outflow. Quantification and insight of the loss processes of the Earth’s atmosphere and ionosphere are also important for understanding the evolution of atmospheres on other celestial bodies.

Udgivelsesdato: 2009-May, A once-daily dose of rivaroxaban 10 mg, an oral, direct Factor Xa inhibitor, was compared with enoxaparin 40 mg subcutaneously once daily for prevention of venous thromboembolism in three studies of patients undergoing elective hip and knee replacement (RECORD programme). A pooled analysis of data from these studies (n = 9581) showed that rivaroxaban was more effective than enoxaparin in reducing the incidence of the composite of symptomatic venous thromboembolism and all-cause mortality at two weeks (0.4% vs 0.8%, respectively, odds ratio 0.44; 95% confidence interval 0.23 to 0.79; p = 0.005), and at the end of the planned medication period (0.5% vs 1.3%, respectively; odds ratio 0.38; 95% confidence interval 0.22 to 0.62; p < 0.001). The rate of major bleeding was similar at two weeks (0.2% for both) and at the end of the planned medication period (0.3% vs 0.2%). Rivaroxaban started six to eight hours after surgery was more effective than enoxaparin started the previous evening in preventing symptomatic venous thromboembolism and all-cause mortality, without increasing major bleeding.

Emitters based on the liquid metal ion source principle have been operating on the Cluster spacecraft between 2000 and 2004, in order to control the spacecraft potential. The resulting reduction of positive spacecraft potential reduces perturbations to the plasma measurements on board. Ion currents up to 40 [LA have been applied, which reduced the energy band in which photoelectrons disturb the plasma electron measurements to values close to the lower detection limit of the instrument. The experience with this method, meanwhile, covers both the maximum and minimum of the present solar cycle and allows one to study the variations of photoemission and other long-term trends and their effects on the measurements. A long-term trend of the controlled spacecraft potential is indeed observed. In addition, it appears that reconstruction of the uncontrolled spacecraft potential from the controlled one is possible if certain conditions are fulfilled. Spacecraft potential control can thereby improve the plasma measurements while still allowing one to estimate the total plasma density from the residual potential.

The Rosetta dual Langmuir probe instrument, LAP, utilizes the multiple powers of a pair of spherical Langmuir probes for measurements of basic plasma parameters with the aim of providing detailed knowledge of the outgassing, ionization, and subsequent plasma processes around the Rosetta target comet. The fundamental plasma properties to be studied are the plasma density, the electron temperature, and the plasma flow velocity. However, study of electric fields up to 8 kHz, plasma density fluctuations, spacecraft potential, integrated UV flux, and dust impacts is also possible. LAP is fully integrated in the Rosetta Plasma Consortium (RPC), the instruments of which together provide a comprehensive characterization of the cometary plasma., QC 20100525

Solar Orbiter will orbit the Sun down to a distance of 0.22 AU allowing detailed in situ studies of important but unexplored regions of the solar wind in combination with coordinated remote sensing of the Sun. In-situ measurements require high quality measurements of particle distributions and electric and magnetic fields. We show that such important scientific topics as the identification of coronal heating remnants, solar wind turbulence, magnetic reconnection and shock formation within coronal mass ejections all require electric field and plasma density measurements in the frequency range from DC up to about 100 Hz. We discuss how such measurements can be achieved using the double-probe technique. We sketch a few possible antenna design solutions.

The effect of neuromuscular block on the anaesthetic depth of hypnosis is an elusive question. We simultaneously investigated the influence of neuromuscular block on the bispectral index, a measure of hypnosis during general anaesthesia, and on the electroencephalogram. Patients were anaesthetized with sevoflurane. Noxious tetanic electrical stimulation was applied on two occasions: before and after profound neuromuscular block achieved with rocuronium. Neuromuscular block significantly attenuated the effect from noxious stimulation on electroencephalogram power and synchrony in the γ band (P<0.05), and the corresponding effect on bispectral index (P<0.02). These findings are probably due to the reduced arousing afferent input from paralysed muscles, and not to changes in the frontal electromyogram. © 2007 Lippincott Williams & Wilkins, Inc.

The present approach to the diagnosis, management and follow-up of anaphylaxis during anaesthesia varies in the Scandinavian countries. The main purpose of these Scandinavian Clinical Practice Guidelines is to increase the awareness about anaphylaxis during anaesthesia amongst anaesthesiologists. It is hoped that increased focus on the subject will lead to prompt diagnosis, rapid and correct treatment, and standardised management of patients with anaphylactic reactions during anaesthesia across Scandinavia. The recommendations are based on the best available evidence in the literature, which, owing to the rare and unforeseeable nature of anaphylaxis, mainly includes case series and expert opinion (grade of evidence IV and V). These guidelines include an overview of the epidemiology of anaphylactic reactions during anaesthesia. A treatment algorithm is suggested, with emphasis on the incremental titration of adrenaline (epinephrine) and fluid therapy as first-line treatment. Recommendations for primary and secondary follow-up are given, bearing in mind that there are variations in geography and resources in the different countries. A list of National Centres from which anaesthesiologists can seek advice concerning follow-up procedures is provided. In addition, an algorithm is included with advice on how to manage patients with previous suspected anaphylaxis during anaesthesia. Lastly, Appendix 2 provides an overview of the incidence, mechanisms and possibilities for follow-up for some common drug groups.

Spacecraft in tenuous plasmas become positively charged because of photoelectron emission. If the plasma is supersonically drifting with respect to the spacecraft, a wake forms behind it. When the kinetic energy of the positive ions in the plasma is not sufficient to overcome the electrostatic barrier of the spacecraft potential, they scatter on the potential structure from the spacecraft rather than get absorbed or scattered by the spacecraft body. For tenuous plasmas with Debye lengths much exceeding the spacecraft size, the potential structure extends far from the spacecraft, and consequently in this case the wake is of transverse dimensions much larger than the spacecraft. This enhanced wake formation process is demonstrated by theoretical analysis and computer simulations. Comparison to observations from the Cluster satellites shows good agreement.

Cold flowing tenuous plasmas are common in the terrestrial magnetosphere, particularly in the polar cap and tail lobe regions, which are filled by the supersonic plasma flow known as the polar wind. Electric field measurements with double-probe instruments in these regions suffer mainly from two error sources: 1) an apparent sunward electric field due to photoemission asymmetries in the probe-boom system and 2) an enhanced negatively charged wake forming behind the spacecraft, which will affect the probe measurements. The authors investigate these effects experimentally by Fourier analysis of the spin signature from the double-probe instrument Electric Fields and Waves (EFW) on the Cluster spacecraft. They show that while the signature due to photoemission asymmetry is very close to sinusoidal, the wake effect is characterized by a spectrum of spin harmonics. The Fourier decomposition can therefore be used for identifying wake effects in the data. As a spin-off, the analysis has also given information on the cold flowing ion population.

Cold ionospheric ions with eV energies are common inthe magnetosphere and can travel far out in the magnetotail.However, they are difficult to measure with conventional ionspectrometers mounted on spacecraft, since the potential of asunlit spacecraft often reaches several tens of volts. In thispaper we present two alternative methods of measuring thecold-ion flow with the Cluster spacecraft and apply them onone case in the magnetotail at 18 RE: 1. Ion spectrometer incombination with artificial spacecraft potential control;2. Deriving ion flow velocity (both perpendicular andparallel) from electric field instruments. The secondmethod takes advantage of the effect on the doubleprobeinstrument of the wake formed behind a spacecraftin a plasma flow. The results from the two methods showgood agreement and are also consistent with polar windmodels and previous measurements at lower altitudes,confirming the continuation of low-energy ion outflows., Corrected in Geophysical Research Letters, 33, 14102 (2006).

QC 20100525