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This corrigendum, in the sense of the Glossary of the International Code of Zoological Nomenclature (ICZN 1999, p. 102), is to ensure that the ICZN criteria for the availability of the two new nomenclatural acts, namely the designations of the neotype of Phoxinus csikii Hankó, 1922 and the lectotype of Phoxinus marsilii Heckel, 1836, are satisfied.

Silibinin, a natural flavonoid antioxidant isolated from extracts of the milk thistle herb, has recently been identified as having anti-hepatotoxic and anticancer properties. In this paper, we investigated the effects of silibinin on behavior and neuroplasticity in mice subjected to chronic unpredictable mild stress (CUMS). After 5 consecutive weeks of CUMS, the mice were treated with silibinin (100 mg/kg, 200 mg/kg and 400 mg/kg by oral gavage) for 3 consecutive weeks. The results showed that silibinin administration significantly alleviated the CUMS-induced depressive-like behavior, including the total number of squares crossed and the frequency of rearing in the open field test, the immobility time in the tail suspension test and the forced swimming test. Furthermore, silibinin treatment increased the levels of brain-derived neurotrophic factor (BDNF), serotonin (5-HT) and norepinephrine (NE) in the prefrontal cortex and hippocampus. Our study provides new insight into the protective effects of silibinin on the depressive status of CUMS mice, specifically by improving neuroplasticity and neurotransmission.

Ischemic injury in the heart is followed by an increase in SNS activity and the higher this activity, the poorer patient outcomes. An index of SNS activity in models of ischemia can be achieved by measuring NE, β-AR, and perhaps indirectly PDE4 to give an intracellular aspect on SNS signaling. A 20 minute ischemia-reperfusion was induced in a rat model with physiological measurements at 2-5 weeks post IR. At 3 weeks post IR, rats displayed increased PDE4 expression, decreased β 1-AR expression, increased plasma NE, decreased tissue NE storage, increased Doppler E/A ratio and unchanged LV ejection fraction. PET analysis with FDG revealed no infarct at 2 weeks, while analysis with [13N]NH3 displayed no resting flow defect but revealed trends in flow reserve impairment as early as 2.5 weeks with recovery at 5 weeks post-surgery. Applications of this model could be non-invasive imaging of PDE4 with (R)-[11C]Rolipram PET at early time points for development towards prognostic and therapy guidance in humans.

Effective population size (Ne) is an important parameter in conservation genetics because it quantifies a population's capacity to resist loss of genetic diversity due to inbreeding and drift. The classical approach to estimate Ne from genetic data involves grouping sampled individuals into discretely defined subpopulations assumed to be panmictic. Importantly, this assumption does not capture the continuous nature of populations genetically isolated by distance. Alternative approaches based on Wright's genetic neighborhood concept quantify the local number of breeding individuals (NS) in a continuous population (as opposed to the global Ne). However, they do not reflect the potential for NS to vary spatially nor do they account for the resistance of a heterogeneous landscape to gene flow (isolation by resistance). Here, we describe an application of Wright's neighborhood concept that provides spatially-explicit estimates of local NS from genetic data in continuous populations isolated by distance or resistance. We delineated local neighborhoods surrounding each sampled individual based on sigma (σ), a measure of the local extent of breeding. When σ was known, the linkage disequilibrium method applied to local neighborhoods produced unbiased estimates of NS that were highly variable across the landscape. NS near the periphery or areas surrounded by high resistance was as much as an order of magnitude lower compared to the center, raising the potential for a spatial component to extinction vortex dynamics in continuous populations. When σ is not known, it may be estimated from genetic data, but two methods we evaluated identified analysis extents that produced considerable bias or error in the estimate of NS. When σ is known or accurately estimated, and the assumptions of Wright's neighborhood are met, the method we describe provides spatially explicit information regarding short-term genetic processes that may inform conservation genetic analyses and management.

Photographer Matthew Murray winner of The Open Category at The Association of Photographers Awards 2014 - \ud \ud There are a lot of photography competitions out there for professionals but the AOP Photographers Awards continues to be regarded as the original and the best - a celebration of exceptional work by the industry’s elite. This competition was only open to Professional Photographer Members of the AOP. It is regarded as THE awards competition for professional photographers and being selected for entry into the book and accompanying exhibition is one of the highest accolades available to photographers around the world.\ud \ud Curators of the 2014 Awards include: Sarah Thomson, head of art production at Fallon London; photographer Rankin; Miles English, creative director at Red Bulletin; photojournalist Tom Stoddart, and photography consultant, Susie Babchick, among others.

In the latest episode in the long-running saga that is the phone hacking affair, Dan Evans, a former journalist at the News of the World and Sunday Mirror, has received a 10 month suspended sentence after being convicted of two counts of phone hacking, one of making illegal payments to officials, and one of perverting the course of justice.\ud \ud Coming so soon after the conviction of Andy Coulson and the acquittal of Rebekah Brooks and others, one could be forgiven for assuming that the whole phone hacking business is now done and dusted.

Through textual analysis this paper explores neo-noir film I, Anna (Southcombe, 2012). This paper promotes the concept of the femme fatale in modern film noir as having much to offer women and ageing studies. Older women on screen have commonly been theorised within two opposing paradigms: ageing as decline, and ageing successfully. This paper argues that through a specific representation of the aged femme fatale body I, Anna offers a destabilisation of the common femme fatale stereotype. This contributes a more nuanced understanding of women and ageing on screen than the representations that are usually discussed in film and/or ageing studies. This paper also marks out this neo-noir British film as an interesting avenue from which to explore the representation of ageing women in film, as existing research has so far focussed on romantic comedy and bio-pic. This paper therefore seeks to add to the growing body of new work on female ageing and representations in the media.

Kafka delves into the nature of paper as enabling agent of bureaucracy –\ud i.e. paperwork – Gitelman’s focus is on “documents” and how they were\ud shaped by print and are now transformed by the digital.

In this article, the British artist Tom Sowden looks at some of the ways in which other artists are publishing their books digitally. From hypertext works to ebooks to blogging; artists are beginning to utilise purely digital publishing tools as a method of producing artists’ books. Their reasons for doing so range from the ease of distribution to a larger audience, to creating a completely new reading experience, to ma- king comments on the move from physical to digital, or at times in order to minimise production costs.\ud Taking a small selection of works that he considers to be important in the lexicon of digital artists’ books, Sowden assesses how artists are using the technology available, what they are doing with it, and whether he considers it successful. Not an exhaustive list, but some key works that are conceptually sound, while demonstrating the myriad ways in which digital technologies can be utilised. By its very nature the digital world is continually adapting, changing and improving, so these works are only a snapshot of what has happened in the recent past and what is happening now.\ud Written from the viewpoint of a practising artist who makes books, the interest in how digital publications can influence artist’s book practice is approached from different angles. It is a keen observation of his peers’ production methods and how new technologies have developed their practice and its content. It is also a survey of how widely these publishing methods are being utilised and offered by artists. It is also Sowden watching how things develop and how new technologies could possibly influence his practice.

Keynote talk at the Beyond the Book symposium, Devon Guild of Craftsmen, Exeter University, Exeter, UK, 15th May 2014. Symposium ran alongside and exhibition of the same name, and both set out to examine the book as physical form as well as a container of ideas and concepts. A household object - the conventional book has only recently been rivalled by the computer screen and electronic text. Exploring this transition, through a variety of formats, from photographs to sculptures, installations and jewellery. The special qualities of the book object are deconstructed and described by these artists who all share an interest in history and memory, language and narrative.

As educators of journalists we are concerned with some of the most fundamental questions about the relationship between the media and democracy, and this we argue, is gendered. Through content analysis and interviews we look at the ways in which women MPs are represented in the British Press. We show that the way in which they are\ud reported (or ignored) positions them as dierent from\ud the ‘male norm’ and this in turn has consequences for the ways in which democratic politics is written about by journalists and experienced by female MPs. A press rep-resentation of women that sometimes serves to suggest politics is a ‘man’s game’, where women are regarded as the aberrant, exception to the rule, can alienate women representatives and likely future candidates. This in turn may have negative consequences for the democratic process, whereby women voters feel unrepresented in Parliament and turn away from political engagement.

Soluble factors are required to mediate nuclear export of protein and RNA through the nuclear pore complex (NPC). These soluble factors include receptors that bind directly to the transport substrate and regulators that determine the assembly state of receptor–substrate complexes. We recently reported the identification of NXT1, an NTF2-related export factor that stimulates nuclear protein export in permeabilized cells and undergoes nucleocytoplasmic shuttling in vivo (Black, B.E., L. Lévesque, J.M. Holaska, T.C. Wood, and B.M. Paschal. 1999. Mol. Cell. Biol. 19:8616–8624). Here, we describe the molecular characterization of NXT1 in the context of the Crm1-dependent export pathway. We find that NXT1 binds directly to Crm1, and that the interaction is sensitive to the presence of Ran-GTP. Moreover, mutations in NXT1 that reduce binding to Crm1 inhibit the activity of NXT1 in nuclear export assays. We show that recombinant Crm1 and Ran are sufficient to reconstitute nuclear translocation of a Rev reporter protein from the nucleolus to an antibody accessible site on the cytoplasmic side of the NPC. Further progress on the export pathway, including the terminal step of Crm1 and Rev reporter protein release, requires NXT1. We propose that NXT1 engages with the export complex in the nucleoplasm, and that it facilitates delivery of the export complex to a site on the cytoplasmic side of NPC where the receptor and substrate are released into the cytoplasm.

The process of protonation in small rare-gas clusters and the study of the most stable structures with He and Ar clusters containing a positively charged hydrogen atom are examined by performing both energy optimization calculations and simulated temperature annealing dynamics. The interaction is modelled via gradient-corrected density functional theory effective potentials and the nuclear dynamics is treated classically. The present results clearly show the presence of a linear symmetric chromophore, He2H+, in the case of helium clusters, while the argon cluster calculations provide evidence for the existence of a more tightly bound ArH+ as the main chromophoric molecular core. Such results confirm earlier findings from quantum chemistry calculations for helium and provide for the first time a realistic modelling for argon clusters.

Oppgaven handler om følgende problemstilling: Er utvisning av utlendinger etter utlendingsloven § 68 b), på bakgrunn av ilagt straff, en dobbeltstraff og i strid med internasjonale menneskerettigheter?

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Professor Stuart Allan from Cardiff University in the UK is one of the leading scholars\ud in contemporary journalism studies. He has made a significant contribution to the development\ud of this research field, having authored or edited seventeen books to date (many\ud of which have been translated into multiple languages), as well as a wide range of journal\ud articles and book chapters. He is a co-founder of the peer-reviewed journal Journalism\ud Education, and serves on the editorial board of ten journals, including Digital Journalism,\ud Journalism: Theory, Practice and Criticism, and New Media & Society.\ud Although he is a man of many interests, Allan’s personal scholarship in journalism studies\ud revolves around four themes: 1) journalism and democracy, where his attention has\ud focused on the evolving role of the journalist in public life (Allan, 2010, 2012; Carter,\ud Branston, and Allan, 1998; Fowler-Watt and Allan, 2013); 2) online news, with a particular\ud interest in citizen journalism and what he terms citizen witnessing (Allan, 2006,\ud 2013; Thorsen and Allan, 2014); 3) the changing nature of war, conflict and crisis reporting\ud (Allan and Zelizer, 2004; Matheson and Allan, 2009; Zelizer and Allan, 2013); and\ud 4) science journalism, with a special interest in how it is evolving in digital contexts (Allan,\ud Adam and Carter, 2000; Allan, 2002; Anderson, Petersen, Wilkinson and Allan, 2009).\ud Further research interests include journalism and human rights, media history, photojournalism,\ud and young people’s civic engagement with digital media.

Catheter-based radiofrequency ablation technology to disrupt both efferent and afferent renal nerves has recently been introduced to clinical medicine after the demonstration of significant systolic and diastolic blood pressure reductions. Clinical trial data available thus far have been obtained primarily in patients with resistant hypertension, defined as standardized systolic clinic blood pressure≥160 mm Hg (or≥150 mm Hg in patients with type 2 diabetes) despite appropriate pharmacologic treatment with at least 3 antihypertensive drugs, including a diuretic agent. Accordingly, these criteria and blood pressure thresholds should be borne in mind when selecting patients for renal nerve ablation. Secondary forms of hypertension and pseudoresistance, such as nonadherence to medication, intolerance of medication, and white coat hypertension, should have been ruled out, and 24-h ambulatory blood pressure monitoring is mandatory in this context. Because there are theoretical concerns with regard to renal safety, selected patients should have preserved renal function, with an estimated glomerular filtration rate≥45 ml/min/1.73 m(2). Optimal periprocedural management of volume status and medication regimens at specialized and experienced centers equipped with adequate infrastructure to cope with potential procedural complications will minimize potential patient risks. Long-term safety and efficacy data are limited to 3 years of follow-up in small patient cohorts, so efforts to monitor treated patients are crucial to define the long-term performance of the procedure. Although renal nerve ablation could have beneficial effects in other conditions characterized by elevated renal sympathetic nerve activity, its potential use for such indications should currently be limited to formal research studies of its safety and efficacy.

This paper examines the public representation of, and family responses to, scientific \ud studies into consciousness in coma-like states. We examine the publicity surrounding \ud high-profile studies using functional Magnetic Resonance Imaging (fMRI) on ‘vegetative’ or \ud ‘minimally conscious’ patients and compare this with family views. Our findings show how, \ud with a few notable exceptions, the research was presented as an amazing breakthrough \ud offering a potential ‘voice’ and choice for patients and hope and comfort for their families. \ud We argue that such representations ignored key limitations, evoked unrealistic visions of \ud recovery, and promoted very narrow representations of family reactions. The comparison \ud between public representations of the science and responses from families with \ud experience of this issue highlights the complex social/medical world into which \ud neurotechnologies intervene, and points to the absence of a range of patient/family \ud perspectives in public discourse. We conclude with suggestions for how those promoting \ud the research, and the journalists reporting its implications, could act to ensure more \ud responsible coverage and enhance public debate.

The Dennis Potter Heritage Project provides a\ud unique opportunity for complex empirical research. It offers the researcher a chance to study the organisational and cultural processes involved in the evolution of a heritage project, created to celebrate a locally important and culturally significant media icon. It promotes\ud the exploration of memory within the locally specific heritage environment of the Forest of Dean and the Dean Heritage Centre’s exhibition space, and it offers the opportunity to study emergent ideas of affect and emotion (Clough 2007; Thrift 2008). Research on the DPHP therefore necessitates a new, complex and innovative approach to methods and methodology. This paper explores autoethnography as both a process a methodology) which can be combined with other qualitative methods, and as a final product (as a mode of writing adopted in the finished research).

A CO2 laser-heated diamond anvil cell was used for performing argon solubility experiments in silicate melts. This technique allowed solubility experiments to be carried out at much higher pressures than in a piston-cylinder-type apparatus. When the beam of the CO2 laser is focused on the silicate sample, argon, acting as a pressure-transmitting medium, melts by conductive heating from the molten sample and can disserve into the melt. Preliminary results for argon solubility in silica and anorthite melts up to 10 GPa are presented. In anorthite melt, the Ar content levels up at 0.5 wt% above 5 GPa. For silica melt, Ar contents increase up to nearly 5 wt% at 5 GPa and decrease below 1% at higher pressures. This behaviour is interpreted as resulting from a profound change in the structure of the melt above 5 GPa, probably related to an increase in the proportion of 4- and 3-membered SiO4 rings.

The translation of named entities (NEs) is a current research topic with regard to the proliferation of electronic documents exchanged through the Internet. So, the need to process these documents with NLP tools becomes necessary and interesting. Formal or semi-formal modeling of these NEs may intervene in both processes of recognition and translation. Indeed, it makes the accumulation of linguistic resources more reliable, limits the impact of linguistic specificities and facilitates the transformation from one representation to another. In this context, we propose a tool for the recognition and translation of Arabic NEs into French, based primarily on formal .representation and a set of transducers. This tool takes into account the integration of a module of transliteration. Its implementation was performed using the NooJ platform and the results obtained proved to be satisfactory; La traduction des Entités Nommées (EN) est un axe de recherche d'actualité vu la multitude des documents électroniques échangés à travers Internet. Ainsi, le besoin de traiter ces documents par des outils de TALN est devenu nécessaire et intéressant. La modélisation formelle ou semi formelle de ces EN peut intervenir dans les processus de reconnaissance et de traduction. En effet, elle permet de rendre plus fiable la constitution des ressources linquistiques, de limiter l'impact des spécificités linguistiques ct de faciliter les transformations d'une représentation à une autre. Dans ce contexte, nous proposons un outil de reconnaissance ct de traduction vers le français des EN arabes basé essentiellement sur une représentation formelle et sur un ensemble de transducteurs. L'outil prend en compte l'intégration d'un module de translittération. L'implémentation de cet outil a été effectuée en utilisant la plateforme NooJ. Les résultats obtenus sont satisfaisants

The translation of named entities (NEs) is a current research topic with regard to the proliferation of electronic documents exchanged through the Internet. So, the need to process these documents with NLP tools becomes necessary and interesting. Formal or semi-formal modeling of these NEs may intervene in both processes of recognition and translation. Indeed, it makes the accumulation of linguistic resources more reliable, limits the impact of linguistic specificities and facilitates the transformation from one representation to another. In this context, we propose a tool for the recognition and translation of Arabic NEs into French, based primarily on formal .representation and a set of transducers. This tool takes into account the integration of a module of transliteration. Its implementation was performed using the NooJ platform and the results obtained proved to be satisfactory; La traduction des Entités Nommées (EN) est un axe de recherche d'actualité vu la multitude des documents électroniques échangés à travers Internet. Ainsi, le besoin de traiter ces documents par des outils de TALN est devenu nécessaire et intéressant. La modélisation formelle ou semi formelle de ces EN peut intervenir dans les processus de reconnaissance et de traduction. En effet, elle permet de rendre plus fiable la constitution des ressources linquistiques, de limiter l'impact des spécificités linguistiques ct de faciliter les transformations d'une représentation à une autre. Dans ce contexte, nous proposons un outil de reconnaissance ct de traduction vers le français des EN arabes basé essentiellement sur une représentation formelle et sur un ensemble de transducteurs. L'outil prend en compte l'intégration d'un module de translittération. L'implémentation de cet outil a été effectuée en utilisant la plateforme NooJ. Les résultats obtenus sont satisfaisants

This paper analyses the factors inducing retailers to adopt genetically modified (GM)-free private standards, using information on 44 retailers operating in 54 countries. Retailers are distinguished between those not using GM ingredients and those using ingredientswhich are potentiallyGMin their private label products. Results from a binary response model show that many of the drivers highlighted in the empirical literature, such as historical factors, communication infrastructure and sectorial conditions, affect the likelihood of adopting GM-free private standards. Moreover, we test additional hypotheses from the political economy of standards formation and of mass media. Key results show that a higher share of government-oriented public media reduces the probability of adopting GM-free private standards, while different genetically modified organism public standards between home and operating countries increase this probability., JRC.J.4-Agriculture and Life Sciences in the Economy

In their study of news values in in the British press Harcup and O’Neill (2001) noted that celebrity was one of the redefinitions of the ‘taxonomy of news values for the twenty-first century’. At the time, Harcup and O’Neill made no judgement about the changes in news values in their redefinition, nor did their research focus on the relative importance and potency of certain \ud news values in the hierarchy of news. Using celebrity case studies from recent decades in the British ‘quality’ press, this article seeks to do just that, demonstrating that the pervasiveness and volume of coverage of celebrity has risen exponentially over 30-plus years. Celebrity/entertainment news values would appear to have risen much higher up the hierarchy of news, guaranteeing extensive coverage if combined with other news values such as surprise and bad news. The findings give rise to a wider debate and concerns about the colonisation of celebrity news and dumbing down in so many areas of British journalism, and the implications for the public \ud and educators.

Matthew Murray’s Ska portrait series looks at a group of people who are so fully immersed in a subculture that music and fashion colour every second of their day. \ud Taking inspiration from his surroundings, Murray talks to Dazed about his experience and inspiration for ‘photographing themes, situations and people that aren't part of the norm,’ and gives us insight into the personal undertones of his up coming projects.

Este artigo analisa a natureza em mudança das relações entre os meios de comunicação social e a chefia da polícia. Com base em estudos prévios (Greer & McLaughlin, 2010), usamos os conceitos de «estrutura inferencial» (Lang & Lang, 1955) e «hierarquia da credibilidade» (Becker, 1967) para analisar o «julgamento pelos media» do antigo comissário do Serviço da Polícia Metropolitana (MPS), Sir Ian Blair. Centramo-nos na reação coletiva e fundamentalmente hostil por parte dos media à declaração de Blair em 2005, que afirmara que: (a) os media são culpados de «racismo institucional» na sua cobertura dos homicídios; e (b) que os homicídios de duas crianças de 10 anos em Soham, 2001, receberam níveis desproporcionados de atenção por parte dos media. Um longo período de aniquilação simbólica na imprensa britânica generalista estabeleceria uma «estrutura inferencial» que definiu Blair como comissário «dado a gafes»: a sua posição na «hierarquia da credibilidade» foi destruída e foi-lhe retirada a legitimidade no cargo. A demissão sem precedentes de um comissário da MPS insere-se num contexto mais abrangente de «jornalismo de ataque» e na crescente «política da indignação» nos meios de comunicação social.

The paper develops a composite index of GMO standards restrictiveness for 60 countries, assigning objective scores to six different regulatory dimensions. Using this index and its components, we empirically investigate the political and economic determinants of GMO regulations for 55 countries, controlling for spatial autocorrelation. Results show that many of the determinants highlighted in the theoretical literature, such as the structure of the agricultural sector and the institutional environment are important determinants of the restrictiveness of the GMO regulation. As a key result there emerges a prominent role of the market for information, showing that the structure of domestic mass media (public vs. private) is an important driver of GMO standards.

In Europe, hantaviruses (Bunyaviridae) are small mammal-associated zoonotic and emerging pathogens that can cause hemorrhagic fever with renal syndrome (HFRS). Puumala virus, the main etiological agent carried by the bank vole Myodes glareolus is responsible for a mild form of HFRS while Dobrava virus induces less frequent but more severe cases of HFRS. Since 2000 in Europe, more than 3000 cases of HFRS have been recorded, in average, each year, which is nearly double compared to the previous decade. In addition to this upside long-term trend, significant oscillations occur. Epidemic years appear, usually every 2-4 years, with an increased incidence, generally in localised hot spots. Moreover, the virus has been identified in new areas in the recent years. A great number of surveys have been carried out in order to assess the prevalence of the infection in the reservoir host and to identify links with different biotic and abiotic factors. The factors that drive the infections are related to the density and diversity of bank vole populations, prevalence of infection in the reservoir host, viral excretion in the environment, survival of the virus outside its host, and human behaviour, which affect the main transmission virus route through inhalation of infected rodent excreta.. At the scale of a rodent population, the prevalence of the infection increases with the age of the individuals but also other parameters, such as sex and genetic variability, interfere. The contamination of the environment may be correlated to the number of newly infected rodents, which heavily excrete the virus. The interactions between these different parameters add to the complexity of the situation and explain the absence of reliable tools to predict epidemics. In this review, the factors that drive the epidemics of hantaviruses in Middle Europe are discussed through a panorama of the epidemiological situation in Belgium, France and Germany.

The Error-Related Negativity (Ne or ERN) is a reliable electrophysiological index of error processing, which has been found to be independent of whether a subject is aware of an error or not. A large Ne was equally seen after errors that were consciously detected (Aware errors) and those that were not (Unaware errors), compared to a small negativity for correct responses (CRN). This suggests a dissociation between an automatic, preconscious error processing mechanism and subjective evaluation. A common concern regarding this finding is that subjects could have been somewhat aware of their errors, but did not report them due to lack of confidence. Here we tested this possibility directly using a betting paradigm which allowed us to separate occasions in which the subjects were confident of their response and trials in which they were unsure. In a choice reaction time task, subjects directly judged the accuracy of each response (correct or error) and then bet on this judgment using a high, medium, or low amount of money. The bets were used to determine the level of confidence the subjects had of their response. The average across all subjects regardless of confidence (betting) measure replicated the reported finding of an equal Ne for Aware and Unaware errors which was larger than the CRN. However, when Ne measurement was confined to high confidence (high bet) trials in confident subjects, a prominent Ne was seen only for Aware errors, while confident Unaware errors (i.e., error trials on which subjects made high bets that they were correct) elicited a response that did not differ from the CRN elicited by truly correct answers. In contrast, for low confidence trials in unconfident subjects, an intermediate and equal Ne/CRN was elicited by Correct responses, Aware and Unaware errors. These results provide direct evidence that the Ne is related to error awareness, and suggest the amplitude of the Ne/CRN depends on individual differences in error reporting and confidence.