330 results on '"MCCARTHY, PATRICK J."'
Search Results
302. Douglas Jerrold: A Life (1803-1857).
- Author
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McCarthy, Patrick J.
- Subjects
LITERARY style ,NONFICTION - Abstract
Reviews the book "Douglas Jerrold: A Life (1803-1857)," by Michael Slater.
- Published
- 2005
303. Book Reviews.
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McCarthy, Patrick J.
- Published
- 1982
304. Overview and status of the Giant Magellan Telescope Project
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Hall, Helen J., Gilmozzi, Roberto, Marshall, Heather K., McCarthy, Patrick J., Fanson, James, Bernstein, Rebecca, Ashby, David, Bigelow, Bruce, Boyadjian, Nune, Bouchez, Antonin, Chauvin, Eric, Donoso, Eduardo, Filgueira, Jose, Goodrich, Robert, Groark, Frank, Jacoby, George, and Pearce, Eric
- Published
- 2016
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305. THE CARNEGIE-SPITZER-IMACS REDSHIFT SURVEY OF GALAXY EVOLUTION SINCE z = 1.5. I. DESCRIPTION AND METHODOLOGY.
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Kelson, Daniel D., Williams, Rik J., Dressler, Alan, McCarthy, Patrick J., Shectman, Stephen A., Mulchaey, John S., Villanueva, Edward V., Crane, Jeffrey D., and Quadri, Ryan F.
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GALACTIC evolution ,REDSHIFT ,STELLAR activity ,INFRARED radiation ,ASTROPHYSICS - Abstract
We describe the Carnegie-Spitzer-IMACS (CSI) Survey, a wide-field, near-IR selected spectrophotometric redshift survey with the Inamori Magellan Areal Camera and Spectrograph (IMACS) on Magellan-Baade. By defining a flux-limited sample of galaxies in Spitzer Infrared Array Camera 3.6 μm imaging of SWIRE fields, the CSI Survey efficiently traces the stellar mass of average galaxies to z ∼ 1.5. This first paper provides an overview of the survey selection, observations, processing of the photometry and spectrophotometry. We also describe the processing of the data: new methods of fitting synthetic templates of spectral energy distributions are used to derive redshifts, stellar masses, emission line luminosities, and coarse information on recent star formation. Our unique methodology for analyzing low-dispersion spectra taken with multilayer prisms in IMACS, combined with panchromatic photometry from the ultraviolet to the IR, has yielded high-quality redshifts for 43,347 galaxies in our first 5.3 deg
2 of the SWIRE XMM-LSS field. We use three different approaches to estimate our redshift errors and find robust agreement. Over the full range of 3.6 μm fluxes of our selection, we find typical redshift uncertainties of σz /(1 + z) ≲ 0.015. In comparisons with previously published spectroscopic redshifts we find scatters of σz /(1 + z) = 0.011 for galaxies at 0.7 ⩽ z ⩽ 0.9, and σz /(1 + z) = 0.014 for galaxies at 0.9 ⩽ z ⩽ 1.2. For galaxies brighter and fainter than i = 23 mag, we find σz /(1 + z) = 0.008 and σz /(1 + z) = 0.022, respectively. Notably, our low-dispersion spectroscopy and analysis yields comparable redshift uncertainties and success rates for both red and blue galaxies, largely eliminating color-based systematics that can seriously bias observed dependencies of galaxy evolution on environment. [ABSTRACT FROM AUTHOR]- Published
- 2014
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306. GALAXY STELLAR MASS FUNCTIONS FROM ZFOURGE/CANDELS: AN EXCESS OF LOW-MASS GALAXIES SINCE z = 2 AND THE RAPID BUILDUP OF QUIESCENT GALAXIES.
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Tomczak, Adam R., Quadri, Ryan F., Tran, Kim-Vy H., Labbé, Ivo, Straatman, Caroline M. S., Papovich, Casey, Glazebrook, Karl, Allen, Rebecca, Brammer, Gabriel B., Kacprzak, Glenn G., Kawinwanichakij, Lalitwadee, Kelson, Daniel D., McCarthy, Patrick J., Mehrtens, Nicola, Monson, Andrew J., Persson, S. Eric, Spitler, Lee R., Tilvi, Vithal, and Dokkum, Pieter van
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GALACTIC evolution ,REDSHIFT ,STELLAR luminosity function ,STELLAR mass ,GALAXIES - Abstract
Using observations from the FourStar Galaxy Evolution Survey (ZFOURGE), we obtain the deepest measurements to date of the galaxy stellar mass function (SMF) at 0.2 < z < 3. ZFOURGE provides well-constrained photometric redshifts made possible through deep medium-bandwidth imaging at 1-2 μm. We combine this with Hubble Space Telescope imaging from the Cosmic Assembly Near-IR Deep Extragalactic Legacy Survey, allowing for the efficient selection of both blue and red galaxies down to stellar masses of ∼10
9.5 M☼ at z ∼ 2.5. The total surveyed area is 316 arcmin2 distributed over three independent fields. We supplement these data with the wider and shallower NEWFIRM Medium-Band Survey to provide stronger constraints at high masses. Several studies at z ⩽ 1.5 have revealed a steepening of the slope at the low-mass end of the SMF, leading to an upturn at masses <1010 M☼ that is not well described by a standard single-Schechter function. We find evidence that this feature extends to at least z ∼ 2 and that it can be found in both the star-forming and quiescent populations individually. The characteristic mass (M*) and slope at the lowest masses (α) of a double-Schechter function fit to the SMF stay roughly constant at Log(M/M☼ ) ∼ 10.65 and ∼ – 1.5, respectively. The SMF of star-forming galaxies has evolved primarily in normalization, while the change in shape is relatively minor. Our data allow us, for the first time, to observe a rapid buildup at the low-mass end of the quiescent SMF. Since z = 2.5, the total stellar mass density of quiescent galaxies (down to 109 M☼ ) has increased by a factor of ∼12, whereas the mass density of star-forming galaxies only increases by a factor of ∼2.2. [ABSTRACT FROM AUTHOR]- Published
- 2014
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307. Shutoff of BZLF1 Gene Expression Is Necessary for Immortalization of Primary B Cells by Epstein-Barr Virus.
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Xianming Yu, McCarthy, Patrick J., Zhenxun Wang, Gorlen, Daniel A., and Mertz, Janet E.
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GENE expression , *B cells , *EPSTEIN-Barr virus , *VIRAL genetics , *MOLECULAR switches , *PROMOTERS (Genetics) , *GENETIC transcription , *GENE silencing , *VIRUSES - Abstract
The BZLF1 gene controls the switch between latent and lytic infection by Epstein-Barr virus (EBV). We previously reported that both the ZV and ZIIR elements within the BZLF1 promoter, Zp, are potent transcription silencers within the context of an intact EBV genome. We report here identification of another sequence element, ZV', which synergized with ZV in repressing Zp via binding ZEB1 or ZEB2. We then determined the phenotype of a variant of EBV strain B95.8 in which the ZV, ZV', and ZIIR elements were concurrently mutated. HEK293 cell lines infected with this triple mutant (tmt) virus spontaneously synthesized 6- to 10-fold more viral BZLF1, BRLF1, BMRF1, and BLLF1 RNAs, 3- to 6-fold more viral Zta, Rta, and EAD proteins, 3- to 5-fold more viral DNA, and 7- to 9-fold more infectious virus than did 293 cell lines latently infected with either the ZV ZV' double mutant (dmt) or ZIIR mutant (mt) virus. While ZV ZV' ZIIR tmt EBV efficiently infected human primary blood B cells in vitro, it was highly defective in immortalizing them. Instead of the nearly complete silencing of BZLF1 gene expression that occurs within 4 days after primary infection with wild-type EBV, the ZV ZV' ZIIR tmt-infected cells continued to synthesize BZLF1 RNA, with 90% of them dying within 9 days postinfection. BL41 cells infected with this "superlytic" virus also exhibited increased synthesis of BZLF1 and BMRF1 RNAs. Thus, we conclude that the ZV, ZV', and ZIIR silencing elements act synergistically to repress transcription from Zp, thereby tightly controlling BZLF1 gene expression, which is crucial for establishing and maintaining EBV latency. [ABSTRACT FROM AUTHOR]
- Published
- 2012
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308. THE RESOLVED STELLAR POPULATION IN 50 REGIONS OF M83 FROM HST/WFC3 EARLY RELEASE SCIENCE OBSERVATIONS.
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Kim, Hwihyun, Whitmore, Bradley C., Chandar, Rupali, Saha, Abhijit, Kaleida, Catherine C., Mutchler, Max, Cohen, Seth H., Calzetti, Daniela, O'Connell, Robert W., Windhorst, Rogier A., Balick, Bruce, Bond, Howard E., Carollo, Marcella, Disney, Michael J., Dopita, Michael A., Frogel, Jay A., Hall, Donald N. B., Holtzman, Jon A., Kimble, Randy A., and McCarthy, Patrick J.
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STELLAR populations ,SPIRAL galaxies ,SUPERGIANT stars ,WOLF-Rayet stars ,CLASSIFICATION of stars - Abstract
We present a multi-wavelength photometric study of ∼15,000 resolved stars in the nearby spiral galaxy M83 (NGC 5236, D = 4.61 Mpc) based on HubbleSpaceTelescope Wide Field Camera 3 observations using four filters: F336W, F438W, F555W, and F814W. We select 50 regions (an average size of 260 pc by 280 pc) in the spiral arm and inter-arm areas of M83 and determine the age distribution of the luminous stellar populations in each region. This is accomplished by correcting for extinction toward each individual star by comparing its colors with predictions from stellar isochrones. We compare the resulting luminosity-weighted mean ages of the luminous stars in the 50 regions with those determined from several independent methods, including the number ratio of red-to-blue supergiants, morphological appearance of the regions, surface brightness fluctuations, and the ages of clusters in the regions. We find reasonably good agreement between these methods. We also find that young stars are much more likely to be found in concentrated aggregates along spiral arms, while older stars are more dispersed. These results are consistent with the scenario that star formation is associated with the spiral arms, and stars form primarily in star clusters and then disperse on short timescales to form the field population. The locations of Wolf-Rayet stars are found to correlate with the positions of many of the youngest regions, providing additional support for our ability to accurately estimate ages. We address the effects of spatial resolution on the measured colors, magnitudes, and age estimates. While individual stars can occasionally show measurable differences in the colors and magnitudes, the age estimates for entire regions are only slightly affected. [ABSTRACT FROM AUTHOR]
- Published
- 2012
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309. RED NUGGETS AT z ∼ 1.5: COMPACT PASSIVE GALAXIES AND THE FORMATION OF THE KORMENDY RELATION.
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Damjanov, Ivana, McCarthy, Patrick J., Abraham, Roberto G., Glazebrook, Karl, Yan, Haojing, Mentuch, Erin, Le Borgne, Damien, Savaglio, Sandra, Crampton, David, Murowinski, Richard, Juneau, Stéphanie, Carlberg, R. G., Jørgensen, Inger, Roth, Kathy, Chen, Hsiao-Wen, and Marzke, Ronald O.
- Published
- 2009
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310. Gemini Deep Deep Survey. VI. Massive Hδ-strong Galaxies at z ≃ 1.
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Le Borgne, Damien, Abraham, Roberto, Daniel, Kathryne, McCarthy, Patrick J., Glazebrook, Karl, Savaglio, Sandra, Crampton, David, Juneau, Stéphanie, Carlberg, Ray G., Chen, Hsiao-Wen, Marzke, Ronald O., Roth, Kathy, Jørgensen, Inger, and Murowinski, Richard
- Published
- 2006
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311. Hubble Space Telescope Imaging and Keck Spectroscopy of z ≈ 6 i-Band Dropout Galaxies in the Advanced Camera for Surveys GOODS Fields.
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Stanway, Elizabeth R., Bunker, Andrew J., McMahon, Richard G., Ellis, Richard S., Treu, Tommaso, and McCarthy, Patrick J.
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- 2004
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312. Three Lyα Emitters at z ≈ 6: Early GMOS/Gemini Data from the GLARE Project.
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Stanway, Elizabeth R., Glazebrook, Karl, Bunker, Andrew J., Abraham, Roberto G., Hook, Isobel, Rhoads, James, McCarthy, Patrick J., Boyle, Brian, Colless, Matthew, Crampton, David, Couch, Warrick, Jørgensen, Inger, Malhotra, Sangeeta, Murowinski, Rick, Roth, Kathy, Savaglio, Sandra, and Tsvetanov, Zlatan
- Published
- 2004
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313. A star-forming galaxy at z = 5.78 in the Chandra Deep Field South.
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Bunker, Andrew J., Stanway, Elizabeth R., Ellis, Richard S., McMahon, Richard G., and McCarthy, Patrick J.
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GALAXIES ,STAR formation ,ASTRONOMICAL instruments ,ASTRONOMICAL photography ,ASTRONOMY - Abstract
We report the discovery of a luminous z = 5.78 star-forming galaxy in the Chandra Deep Field South. This galaxy was selected as an 'i-drop' from the GOODS public survey imaging with the Hubble Space Telescope/Advanced Camera for Surveys (object 3 in the work of Stanway, Bunker & McMahon 2003). The large colour of (I' - z')[SUBAB] = 1.6 indicated a spectral break consistent with the Lyman a forest absorption shortward of Lyman a at z ≈ 6. The galaxy is very compact (marginally resolved with ACS with a half-light radius of 0.08 arcsec, so r[SUBhl] < 0.5 h[SUP-1,SUB70] kpc). We have obtained a deep (5.5 h) spectrum of this z'[SUBAB] = 24.7 galaxy with the DEIMOS optical spectrograph on the Keck Telescope, and here we report the discovery of a single emission line centred on 8245 Å detected at 20σ with a flux of f ≈ 2 × 10[SUP-17] erg cm[SUP-2]s[SUP-1]. The line is clearly resolved with detectable structure at our resolution of better than 55 km s[SUP-1], and the only plausible interpretation consistent with the ACS photometry is that we are seeing Lyman a emission from a z = 5.78 galaxy. This is the highest redshift galaxy to be discovered and studied using HST data. The velocity width (Δν[SUBFWHM] = 260 km s[SUP-1]) and rest-frame equivalent width (W[SUPLyα,SUBrest] = 20 Å) indicate that this line is most probably powered by star formation, as an AGN would typically have larger values. The starburst interpretation is supported by our non-detection of the high-ionization N v λ 1240-Å emission line, and the absence of this source from the deep Chandra X-ray images. The star formation rate inferred from the rest-frame UV continuum is 34 h[SUP-2,SUB70] M[SUB&Odot; yr[SUP-1] (Ω[SUBM] = 0.3, Ω[SUB∇] = 0.7). This is the most luminous starburst known at z > 5. Our spectroscopic redshift for this object confirms the validity of the I' -drop technique of Stanway et al. to select star-forming... [ABSTRACT FROM AUTHOR]
- Published
- 2003
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314. Hubble Space Telescope Snapshot Survey of 3CR Radio Source Counterparts. III. Radio Galaxies with z < 0.1.
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Martel, André R., Baum, Stefi A., Sparks, William B., Wyckoff, Eric, Biretta, John A., Golombek, Daniel, Macchetto, Ferdinando D., de Koff, Sigrid, McCarthy, Patrick J., and Miley, George K.
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- 1999
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315. New Optical Fields and Candidates of 10 3C Radio Sources. I. The R-Band Images.
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Martel, André R., Sparks, William B., Macchetto, Duccio, Baum, Stefi A., Biretta, John A., Golombek, Daniel, McCarthy, Patrick J., de Koff, Sigrid, and Miley, George K.
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- 1998
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316. The Letters of Charles Dickens (Book).
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McCarthy, Patrick J.
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BIOGRAPHY (Literary form) ,NONFICTION - Abstract
Reviews the book 'The Letters of Charles Dickens,' edited by Graham Storey and K.J. Fielding.
- Published
- 1982
317. Ultrafunctions, Projective Function Geometry, and Polynomial Functional Equations
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McCarthy, Patrick J.
- Abstract
Some non-linear functional equations involving iterates have fascinating properties. In this paper, the polynomial functional equations (P)
$${f}^{N}\left(x\right)=\sum _{n=0}^{N-1}{A}_{}{f}^{n}\left(x\right)$$ are studied, where the An are real constants, and the powers denote the iterates of f: R → R. Each such equation can be interpreted as a linear invariance condition for a graph Γ ⊂ R × RN−1 associated with f. The attempt to express this condition in simple canonical form leads to the idea that functions (or, rather, graphs) can be interpreted as projective objects. This motivates the introduction of the space of ultrafunctions, a ‘projective function space’ obtained by adjoining suitable ‘functions at infinity’ to the affine space of ordinary functions. This enables (P) to be reduced, by a projective transformation, to a purely linear ultrafunctional equation which is easily solved. Explicit formulae, involving ultrafunctions from an explicitly described family, are given for the general continuous (ordinary function) solution in representative generic cases. The relationship between these solutions and known ‘explicit functions’ is discussed. Further applications are briefly described; in particular, ‘functional continued fractions’ are introduced, and their convergence is examined.- Published
- 1987
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318. The Classification of the Conjugacy Classes of the Full Group of Homeomorphisms of an Open Interval and the General Solution of Certain Functional Equations
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McCarthy, Patrick J. and Stephenson, W.
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We present a classification of the conjugacy classes of the full group G of self-homeomorphisms of an open interval I of the real line, and apply this classification to the solution of certain functional equations. Namely, for β: I → I a given continuous bijection and n a positive integer we find, explicitly, the general continuous solution f: I → I of the functional equation fn = β (F), where the power denotes iterated function composition. The given β is necessarily increasing or decreasing, and the solutions of (F) are naturally grouped into conjugacy classes of G. We find that (i) for n odd, (F) admits exactly one conjugacy class of solutions; (ii) for n even and β increasing, there is only one conjugacy class of increasing solutions of (F), whilst the number of conjugacy classes d of decreasing solutions of (F) depends on the symmetry properties of β and can be d = 0, 1, 2, 3,…, ∞ (iii) for n even and β decreasing, (F) admits no continuous solutions at all and, in this case, we show that any solution of (F) must have infinitely many discontinuities.
- Published
- 1966
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319. Gravity and the non-linear growth of structure in the Carnegie-Spitzer-IMACS Redshift Survey.
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Kelson, Daniel D, Abramson, Louis E, Benson, Andrew J, Patel, Shannon G, Shectman, Stephen A, Dressler, Alan, McCarthy, Patrick J, Mulchaey, John S, and Williams, Rik J
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MONTE Carlo method , *SPECIFIC gravity , *GALACTIC evolution , *LOGNORMAL distribution , *GRAVITY , *EVOLUTIONARY theories , *GALAXY formation , *REDSHIFT - Abstract
A key obstacle to developing a satisfying theory of galaxy evolution is the difficulty in extending analytic descriptions of early structure formation into full non-linearity, the regime in which galaxy growth occurs. Extant techniques, though powerful, are based on approximate numerical methods whose Monte Carlo-like nature hinders intuition building. Here, we develop a new solution to this problem and its empirical validation. We first derive closed-form analytic expectations for the evolution of fixed percentiles in the real-space cosmic density distribution, averaged over representative volumes observers can track cross-sectionally. Using the Lagrangian forms of the fluid equations, we show that percentiles in δ – the density relative to the median – should grow as |$\delta (t)\propto \delta _{0}^{\alpha }\, t^{\beta }$| , where α ≡ 2 and β ≡ 2 for Newtonian gravity at epochs after the overdensities transitioned to non-linear growth. We then use 9.5 square degress of Carnegie-Spitzer-IMACS Redshift Survey data to map galaxy environmental densities over 0.2 < z < 1.5 (∼7 Gyr) and infer α = 1.98 ± 0.04 and β = 2.01 ± 0.11 – consistent with our analytic prediction. These findings – enabled by swapping the Eulerian domain of most work on density growth for a Lagrangian approach to real-space volumetric averages – provide some of the strongest evidence that a lognormal distribution of early density fluctuations indeed decoupled from cosmic expansion to grow through gravitational accretion. They also comprise the first exact, analytic description of the non-linear growth of structure extensible to (arbitrarily) low redshift. We hope these results open the door to new modelling of, and insight-building into, galaxy growth and its diversity in cosmological contexts. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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320. Dickens Studies Annual (Book).
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McCarthy, Patrick J.
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ENGLISH literature , *NONFICTION - Abstract
Reviews the book 'Dickens Studies Annual: Essays on Victorian Fiction,' vol. 5, edited by Michael Timko, Fred Kaplan and Edward Guiliano.
- Published
- 1988
321. Matthew Arnold: A Life.
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McCarthy, Patrick J.
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LITERARY style ,NONFICTION - Abstract
Reviews the book "Matthew Arnold: A Life," by Park Honan.
- Published
- 1983
322. Herpes Simplex Proctitis Mimicking Inflammatory Bowel Disease in a Teenaged Male.
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Sandgren, Kristen E., Price, Nathan B., Bishop, Warren P., and McCarthy, Patrick J.
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PROCTITIS , *ANAL disease diagnosis , *INFLAMMATORY bowel diseases , *SEXUALLY transmitted diseases , *ANAL diseases , *DISEASE risk factors , *THERAPEUTICS - Abstract
We report the case of a 17-year-old male who was initially assessed for pain with defecation, bloody rectal discharge, and diarrhea, consistent with proctitis. Though proctitis is most commonly due to inflammatory bowel disease (IBD), infectious etiologies must also be considered, including sexually transmitted causes of infectious proctitis. In discussion of his sexual history, he identified as homosexual and acknowledged engaging in receptive anal intercourse. Rectal biopsies obtained via colonoscopy were culture-positive for herpes simplex virus (HSV), leading to a diagnosis of HSV proctitis and treatment with an appropriate antiviral medication. HSV proctitis is more common in individuals with high-risk sexual practices, including men who have sex with men. While this may be an uncommon diagnosis for pediatricians to make in practice, a high clinical index of suspicion for sexually transmitted infectious proctitis in those with risk factors must be maintained in order to facilitate appropriate testing, treatment, and counseling of affected individuals. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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323. Preliminary results from a spectroscopic Lyα survey at redshift 5.7 with IMACS
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Martin, Crystal L., Sawicki, Marcin, Dressler, Alan, and McCarthy, Patrick J.
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SPECTRUM analysis , *SURVEYS , *REDSHIFT , *ASTROPHYSICS , *METAPHYSICAL cosmology - Abstract
Abstract: We describe preliminary results from an ultra-sensitive, spectroscopic emission-line survey and illustrate the challenges inherent in identifying high-redshift Lyα emitters. Our multi-slit windows technique complements other types of emission-line surveys. Narrowband imaging surveys cover large areas of sky but only detect much brighter objects. Longslit spectra taken along cluster caustics yield intrinsically fainter lensed Lyα emitters but probe small volumes of space. We have observed the COSMOS deep field and a field at 15h +00. To a line flux of a few∼×10−18 ergss−1 cm−2, we found 150 emission-line sources (with no detectable continuum) among 4 masks. These candidates are being re-observed with broad spectral coverage to determine the line identity. To date, the interloper to Lyα ratio is about 8:1. The sky positions of the Lyα candidates generally do not coincide with those of foreground objects in ultra-deep r band or i′ images – consistent with the presence of a strong Lyman break. [Copyright &y& Elsevier]
- Published
- 2006
- Full Text
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324. The influence of thermal plasma profiles on low-frequency Alfvén eigenmode dynamics in a tokamak
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Curran, Diarmuid B. and McCarthy, Patrick J.
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Kinetic ,Plasma ,Physics::Plasma Physics ,Tokamak ,Alfvén eigenmode ,Nuclear fusion ,BAE - Abstract
The confinement of fast particles, present in a tokamak plasma as nuclear fusion products and through external heating, will be essential for any future fusion reactor. Fast particles can be expelled from the plasma through their interaction with Alfvén eigenmode (AE) instabilities. AEs can exist in gaps in the Alfvén continuum created by plasma equilibrium non-uniformities. In the ASDEX Upgrade tokamak, low-frequency modes in the frequency range from f ≈ 10 − 90kHz, including beta-induced Alfvén eigenmodes (BAEs) and lower frequency modes with mixed Alfvén and acoustic polarisations, have been observed. These exist in gaps in the Alfvén continuum opened up by geodesic curvature and finite plasma compressibility. In this thesis, a kinetic dispersion relation is solved numerically to investigate the influence of thermal plasma profiles on the evolution of these low-frequency modes during the sawtooth cycle. Using information gained from various experimental sources to constrain the equilibrium reconstructions, realistic safety factor profiles are obtained for the analysis using the CLISTE code. The results for the continuum accumulation point evolution are then compared with experimental results from ASDEX Upgrade during periods of ICRH only as well as for periods with both ICRH and ECRH applied simultaneously. It is found that the diamagnetic frequency plays an important role in influencing the dynamics of BAEs and low-frequency acoustic Alfvén eigenmodes, primarily through the presence of gradients in the thermal plasma profiles. Different types of modes that are observed during discharges heated almost exclusively by ECRH were also investigated. These include electron internal transport barrier (eITB) driven modes, which are observed to coincide with the occurrence of an eITB in the plasma during the low-density phase of the discharge. Also observed are BAE-like modes and edge-TAEs, both of which occur during the H-mode phase of the discharge.
- Published
- 2014
325. Inter-ELM evolution of the edge current density profile on the ASDEX upgrade tokamak
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Dunne, Michael G. and McCarthy, Patrick J.
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Physics::Plasma Physics ,MHD ,Current density ,Tokamak ,Edge localised modes ,Nuclear fusion ,Laboratory plasma ,Plasma diagnostics - Abstract
The sudden decrease of plasma stored energy and subsequent power deposition on the first wall of a tokamak due to edge localised modes (ELMs) is potentially detrimental to the success of a future fusion reactor. Understanding and control of ELMs is critical for the longevity of these devices and also to maximise their performance. The commonly accepted picture of ELMs posits a critical pressure gradient and current density in the plasma edge, above which coupled magnetohy drodynamic peeling-ballooning modes become unstable. Much analysis has been presented in recent years on the spatial and temporal evolution of the edge pressure gradient. However, the edge current density has typically been overlooked due to the difficulties in measuring this quantity. In this thesis, a novel method of current density recovery is presented, using the equilibrium solver CLISTE to reconstruct a high resolution equilibrium utilising both external magnetic and internal edge kinetic data measured on the ASDEX Upgrade tokamak. The evolution of the edge current density relative to an ELM crash is presented, showing that a resistive delay in the buildup of the current density is unlikely. An uncertainty analysis shows that the edge current density can be determined with an accuracy consistent with that of the kinetic data used. A comparison with neoclassical theory demonstrates excellent agreement be- tween the current density determined by CLISTE and the calculated profiles. Three ELM mitigation regimes are investigated: Type-II ELMs, ELMs sup- pressed by external magnetic perturbations, and Nitrogen seeded ELMs. In the first two cases, the current density is found to decrease as mitigation on- sets, indicating a more ballooning-like plasma behaviour. In the latter case, the flux surface averaged current density can decrease while the local current density increases, providing a mechanism to suppress both the peeling and ballooning modes.
- Published
- 2013
326. Validation of a food checklist for oncology patients
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Amend, Christa, Human Nutrition and Foods, Hertzler, Ann A., Webb, Ryland E., and McCarthy, Patrick J.
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Cancer -- Patients -- Diet therapy ,digestive, oral, and skin physiology ,LD5655.V855 1993.A446 - Abstract
A Food Checklist, based on the Food Guide pyramid, was developed and validated as a quick method to determine the adequacy of dietary energy and protein intakes in cancer patients. Food intake data were monitored for 34 hospitalized oncology patients for two days. Caloric and protein intake estimates computed using the Food Checklist were correlated 0.99 (p
- Published
- 1993
327. Hiring in the Pediatric Hospital Medicine Board Certification Era: PHM Leader Perspectives.
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Osburn TS, McCarthy PJ, Dawlett M, LaRussa L, DeLeon S, and McKnight H
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- Humans, Cross-Sectional Studies, Hospital Medicine education, Pediatrics education, Specialty Boards, United States, Hospitalists education, Leadership, Surveys and Questionnaires, Certification, Personnel Selection standards, Hospitals, Pediatric
- Abstract
Objectives: The designation of pediatric hospital medicine (PHM) as a board-certified (BC) subspecialty has led to uncertainty about the importance of PHM board certification in hiring pediatric hospitalists and ambiguity in counseling trainees interested in PHM careers about the decision to pursue fellowship. We sought to determine the importance of PHM board eligibility or certification in hiring practices., Methods: We conducted an online, cross-sectional, survey-based study of individuals who self-identified as PHM division leadership utilizing the PHM Division Director Listserv and participant recruitment at a national meeting., Results: A total of 86 responses were received. A total of 64% (30/47) of university-setting hospitals, 77% (17/28) of community hospitals, and 100% (11/11) of combined settings reported that they will hire applicants who are not board-eligible (BE) or BC (P = .83). Of the hospitals who will be hiring non-BE hospitalists, 50% of university settings, 77% of community settings, and 55% of combined settings plan to give equal consideration to both BE and non-BE applicants (P = .21). A total of 57% (21/37) of programs with a PHM fellowship felt that fellowship training was an important or very important consideration in hiring, compared with 27% (13/49) of programs without a PHM fellowship (P = .04)., Conclusions: Programs with a PHM fellowship were significantly more likely to believe that fellowship training is an important consideration in hiring hospitalists. PHM board certification and fellowship training are perceived as more important by university-based programs, although all settings will consider hiring applicants who are not BC or BE., (Copyright © 2024 by the American Academy of Pediatrics.)
- Published
- 2024
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328. A 'PEaRL' of Support and Cooperative Learning: A Pilot Study Shifting the Sands of the Dreaded Morbidity and Mortality Conference.
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Yale SC, Porada K, and McCarthy PJ
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- Humans, Pilot Projects, Wisconsin, Female, Pediatrics education, Male, Patient Safety, Morbidity, Curriculum
- Abstract
Background: When unanticipated and/or poor patient outcomes occur, clinicians frequently experience guilt, anger, psychological distress, and fear, which can be intensified by traditional morbidity and mortality conferences., Methods: The Pediatric Event Review and Learning (PEaRL) curriculum was developed to discuss unanticipated and/or poor patient outcomes and foster support while highlighting foundational safety concepts. Pre- and post-implementation evaluations of quarterly cased-based sessions were completed., Results: All respondents endorsed that unanticipated and/or poor patient outcomes affected their mood, well-being, and functioning. Post-implementation of the PEaRL curriculum, significantly more respondents endorsed existence of a safe environment and structured format to discuss these outcomes, as well as feeling more supported., Discussion: The PEaRL curriculum provides a valuable opportunity for trainees and experienced clinicians alike to explore and discuss unanticipated and/or poor patient outcomes while addressing key patient safety principles., (Copyright© Board of Regents of the University of Wisconsin System and The Medical College of Wisconsin, Inc.)
- Published
- 2024
329. Perfusion Methods and Modifications to the Cardiopulmonary Bypass Circuit for Midline Unifocalization Procedures.
- Author
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Margetson TD, Sleasman J, Kollmann S, McCarthy PJ, Jahadi O, Sheff D, Shuttleworth P, Mainwaring RD, and Hanley FL
- Subjects
- Cardiopulmonary Bypass, Collateral Circulation, Humans, Infant, Pulmonary Artery, Cardiac Surgical Procedures, Pulmonary Atresia
- Abstract
Pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries (PA/VSD/MAPCAs) is a rare form of congenital heart disease. The midline unifocalization procedure has been developed for the treatment of PA/VSD/MAPCAs. These are complex and very lengthy procedures that require an entirely different method of perfusion. The purpose of this study was to review our perfusion modifications to support these unifocalization procedures. Sixty-four unifocalization procedures have been performed at our institution during the past 3 years. The median age was 4.1 months (range 1 month-3.5 years) and the median weight at surgery was 4.5 kg (range 3.5-19 kg). The median duration of cardiopulmonary bypass was 352 minutes (range 128-629 minutes), and the median duration of cross-clamp was 24 minutes (range 14-72 minutes). The conduct of surgery included cooling to a rectal perfusion temperature of 25° and a flow rate of 100 mL/kg/min. A pH-stat strategy and del Nido cardioplegia were used. Modifications to the cardiopulmonary bypass circuit include upsizing the oxygenator, reservoir, cannulae, vent catheter, and tubing. All circuits were modified to include the capability of performing an intraoperative flow study. This study is used to determine whether the VSD can be closed during surgery. A collateral flow study circuit is also set up for first-time operations to measure the residual collateral flow after all of the MAPCAs have been harvested. Patients who require midline unifocalization will invariably require very lengthy periods of support on cardiopulmonary bypass. We have adapted our perfusion circuitry to prepare for the demands on the bypass circuit to meet the requirements of this patient population. Our institution has developed a systematic approach for the conduct of perfusion to best serve our patients presenting with PA/VSD/MAPCAs.
- Published
- 2019
330. A case series involving young children presenting with accidental ingestion of amphetamine based stimulants.
- Author
-
Wood KE, McCarthy PJ, and Krasowski MD
- Abstract
•Attention Deficity Hyperactivity Disorder (ADHD) affects adults and children.•Stimulant prescribing for ADHD is increasing.•Overdose of amphetamine based stimulants results in a sympathomimetic toxidrome.•Lisdexamfetamine dimesylate is the first prodrug stimulant developed to treat ADHD.
- Published
- 2018
- Full Text
- View/download PDF
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