507 results on '"J P, Sullivan"'
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502. Forward angle scattering effects in the measurement of total cross sections for positron scattering.
- Author
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J P Sullivan, C Makochekanwa, A Jones, P Caradonna, D S Slaughter, J Machacek, R P McEachran, D W Mueller, and S J Buckman
- Subjects
- *
POSITRON scattering , *DIFFERENTIAL cross sections , *ANGULAR distribution (Nuclear physics) , *FORCE & energy , *PHYSICAL measurements - Abstract
Measurements of total scattering by positron impact have typically excluded a significant portion of the forward scattering angles of the differential cross section. This paper demonstrates the effect that this can have on measurements of the total cross section. We show that much of the apparent disagreement between experimental measurements of positron scattering from atoms and molecules may be explained by this excluded angular range. It is shown that this same effect may also lead to an anomalous energy dependence of some cross sections. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
- View/download PDF
503. Implementing a 48 h EWTD-compliant rota for junior doctors in the UK does not compromise patients safety: assessor-blind pilot comparison.
- Author
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F. P. Cappuccio, A. Bakewell, F. M. Taggart, G. Ward, C. Ji, J. P. Sullivan, M. Edmunds, R. Pounder, C. P. Landrigan, S. W. Lockley, E. Peile, and on behalf of the Warwick EWTD Working Group
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MEDICAL practice ,HEALTH of physicians - Abstract
Background: There are currently no field data about the effect of implementing European Working Time Directive (EWTD)-compliant rotas in a medical setting. Surveys of doctorsâ subjective opinions on shift work have not provided reliable objective data with which to evaluate its efficacy. Aim: We therefore studied the effects on patients safety and doctorsâ work-sleep patterns of implementing an EWTD-compliant 48 h work week in a single-blind intervention study carried out over a 12-week period at the University Hospitals Coventry & Warwickshire NHS Trust. We hypothesized that medical error rates would be reduced following the new rota. Methods: Nineteen junior doctors, nine studied while working an intervention schedule of Results: Average scheduled work hours were significantly lower on the intervention schedule [43.2 (SD 7.7) (range 26.0â60.0) vs. 52.4 (11.2) (30.0â77.0) h/week; P P = 0.095]. During a total of 4782 patient-days involving 481 admissions, 32.7% fewer total medical errors occurred during the intervention than during the traditional rota (27.6 vs. 41.0 per 1000 patient-days, P = 0.006), including 82.6% fewer intercepted potential adverse events (1.2 vs. 6.9 per 1000 patient-days, P = 0.002) and 31.4% fewer non-intercepted potential adverse events (16.6 vs. 24.2 per 1000 patient-days, P = 0.067). Doctors reported worse educational opportunities on the intervention rota. Conclusions: Whilst concerns remain regarding reduced educational opportunities, our study supports the hypothesis that a 48 h work week coupled with targeted efforts to improve sleep hygiene improves patient safety. [ABSTRACT FROM AUTHOR]
- Published
- 2009
504. Martial : The Unexpected Classic
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J. P. Sullivan and J. P. Sullivan
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- Epigrams, Latin--History and criticism, Poets, Latin--Biography, Rome in literature
- Abstract
This is the first full-length study in English of the Roman poet Martial's life, poetry and politics, as well as of the survival of his fifteen books of epigrams and short poems from his death around AD 104 to the present. The subjects examined include his defence of epigram as an art form, his misogyny and obscenity, his style, wit and humour, and, not least, his imperial propaganda. The concluding part of the work examines his high reputation in the Renaissance and the later censorship and neglect of his work until comparatively recently. All the material is presented for a modern objective assessment of his achievement, without in any way disguising the unpleasant aspects of his genius, and the political and literary pressures on poets in Rome at that period.
- Published
- 1991
505. Ivermectin: a positive allosteric effector of the alpha7 neuronal nicotinic acetylcholine receptor
- Author
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Jean-Pierre Changeux, Sonia Bertrand, Bruno Buisson, Ryoko M. Krause, Jean-Luc Galzi, Daniel Bertrand, Pierre-Jean Corringer, Centre médical universitaire de Genève (CMU), Neurobiologie moléculaire, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Récepteurs et Cognition (RC), Collège de France (CdF (institution))-Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), This work was supported by the Swiss National Foundation and the Office Fédéral de l’Education et des Sciences (D.B.) and Collège de France, Association Française contre la Myopathie, Institut de la Santé et de la Recherche Médicale, Direction de la Recherche Etudes et Techniques, and Commission of the European Communities (Biotech, Biomed) (J.P.C.)., We thank Drs. S. P. Arneric, J. P. Sullivan, and M. Gopalakrishnan (Abbott Labs, Abbott Park, IL) for kindly providing the K-28 cells. Human α7 cDNA was kindly provided by Prof. J. Lindstrom., Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), and Collège de France (CdF (institution))-Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)
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Models, Molecular ,alpha7 Nicotinic Acetylcholine Receptor ,[SDV]Life Sciences [q-bio] ,Xenopus ,MESH: Neurons ,Cooperativity ,Receptors, Nicotinic ,Pharmacology ,MESH: Allosteric Regulation ,Membrane Potentials ,MESH: Recombinant Proteins ,Xenopus laevis ,0302 clinical medicine ,MESH: Structure-Activity Relationship ,MESH: Animals ,Nicotinic Agonists ,Anthelmintics ,Neurons ,0303 health sciences ,MESH: Chickens ,Long-term potentiation ,[SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences ,Recombinant Proteins ,3. Good health ,Nicotinic acetylcholine receptor ,Nicotinic agonist ,MESH: Anthelmintics ,MESH: Receptors, Nicotinic ,Molecular Medicine ,Ion Channel Gating ,MESH: Models, Molecular ,Allosteric regulation ,Biology ,Transfection ,Partial agonist ,MESH: Ivermectin ,Cell Line ,MESH: Oocytes ,MESH: alpha7 Nicotinic Acetylcholine Receptor ,Structure-Activity Relationship ,03 medical and health sciences ,Allosteric Regulation ,Chloride Channels ,MESH: Xenopus laevis ,parasitic diseases ,MESH: Nicotinic Agonists ,Animals ,Humans ,Point Mutation ,MESH: Membrane Potentials ,030304 developmental biology ,Acetylcholine receptor ,MESH: Point Mutation ,Binding Sites ,Ivermectin ,MESH: Humans ,MESH: Transfection ,Cell Membrane ,MESH: Chloride Channels ,MESH: Ion Channel Gating ,biology.organism_classification ,MESH: Cell Line ,MESH: Solubility ,Solubility ,MESH: Binding Sites ,Oocytes ,[SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology ,Chickens ,030217 neurology & neurosurgery ,MESH: Cell Membrane - Abstract
International audience; We report that preapplication of ivermectin, in the micromolar range, strongly enhances the subsequent acetylcholine-evoked current of the neuronal chick or human alpha7 nicotinic acetylcholine receptors reconstituted in Xenopus laevis oocytes and K-28 cells. This potentiation does not result from nonspecific Cl- currents. The concomitant increase in apparent affinity and cooperativity of the dose-response curve suggest that ivermectin acts as a positive allosteric effector. This interpretation is supported by the observation of an increase in efficiency of a partial agonist associated with the potentiation and by the differential effect of ivermectin on mutants within the M2 channel domain. Ivermectin effects reveal a novel allosteric site for pharmacological agents on neuronal alpha7 nicotinic acetylcholine receptors.
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- 1998
- Full Text
- View/download PDF
506. Study of collective flow in heavy ion collisions
- Author
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Bizard, G., Peter, J., Shen, W.Q., Sullivan, J.P., Brou, R., Cussol, D., Louvel, M., Patry, J.P., Régimbart, R., Steckmeyer, J.C., Tamain, B., Crema, E., Doubre, H., Hagel, K., Jin, G.M., Peghaire, A., Saint-Laurent, F., Cassagnou, Y., Legrain, R., Lebrun, C., Rosato, E., Macgrath, R., Jeong, S.C., Lee, S.M., Nagashima, Y., Nakagawa, T., Ogihara, M., Kasagi, J., Motobayashi, T., Laboratoire de physique corpusculaire de Caen (LPCC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), M.Ohta, B.Remaud, G., Bizard, J., Péter, W. Q., Shen, J. P., Sullivan, D., Cussol, R., Brou, M., Louvel, J. P., Patry, R., Régimbart, J. C., Steckmeyer, B., Tamain, E., Crema, H., Doubre, K., Hagel, G. M., Jin, A., Péghaire, F., Saint Laurent, Y., Cassagnou, R., Legrain, C., Lebrun, Rosato, Elio, R., Mcgrath, S. C., Jeong, S. M., Lee, Y., Nagashima, T., Nakagawa, M., Ogihara, J., Kasagi, T., Motobayashi, and Guesnon, Sandrine
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[PHYS.NEXP] Physics [physics]/Nuclear Experiment [nucl-ex] ,[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex] - Published
- 1991
507. Inversion of collective matter flow in nucleus-nucleus collisions, measured with a 4$\pi$ charged particle array
- Author
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Peter, J., Sullivan, J.P., Bizard, G., Cussol, D., Brou, R., Louvel, M., Patry, J.P., Régimbart, R., Steckmeyer, J.C., Tamain, B., Crema, E., Doubre, H., Hagel, K., Jin, G.M., Peghaire, A., Saint-Laurent, F., Cassagnou, Y., Legrain, R., Lebrun, C., Rosato, E., Macgrath, R., Jeong, S.C., Lee, S.M., Nagashima, Y., Nakagawa, T., Ogihara, M., Kasagi, J., Motobayashi, T., Laboratoire de physique corpusculaire de Caen (LPCC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), I.Iori, J., Péter, J. P., Sullivan, D., Cussol, G., Bizard, R., Brou, M., Louvel, J. P., Patry, R., Régimbart, J. C., Steckmeyer, B., Tamain, E., Crema, H., Doubre, K., Hagel, G. M., Jin, A., Péghaire, F., Saint Laurent, Y., Cassagnou, R., Legrain, C., Lebrun, Rosato, Elio, R., Mcgrath, S. C., Jeong, S. M., Lee, Y., Nagashima, T., Nakagawa, M., Ogihara, J., Kasagi, T., Motobayashi, and Guesnon, Sandrine
- Subjects
[PHYS.NEXP] Physics [physics]/Nuclear Experiment [nucl-ex] ,[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex] - Published
- 1991
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