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232 results on '"Williams, Kaye J."'

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201. Utilizing the adjuvant proper ties of CD1d-dependent NK T cells in T cell-mediated immunotherapy.

202. 3D DESI-MS lipid imaging in a xenograft model of glioblastoma: a proof of principle.

203. Preclinical dosimetry: exploring the use of small animal phantoms.

204. Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action.

205. Targeting Hypoxia-Inducible Factor-1α in Pancreatic Cancer: siRNA Delivery Using Hyaluronic Acid-Displaying Nanoparticles.

206. Dose escalation of tolinapant (ASTX660) in combination with standard radical chemoradiotherapy in cervical cancer : a study protocol for a phase 1b TiTE-CRM clinical trial (CRAIN) in UK secondary care centres.

207. PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models.

208. Roadmap for precision preclinical x-ray radiation studies.

209. Spatial Gene Expression Changes in the Mouse Heart After Base-Targeted Irradiation.

210. Invasion and Secondary Site Colonization as a Function of In Vitro Primary Tumor Matrix Stiffness: Breast to Bone Metastasis.

211. Role of stiffness and physico-chemical properties of tumour microenvironment on breast cancer cell stemness.

212. Habitat Imaging of Tumors Enables High Confidence Sub-Regional Assessment of Response to Therapy.

213. A preclinical radiotherapy dosimetry audit using a realistic 3D printed murine phantom.

214. Immunomodulation by radiotherapy in tumour control and normal tissue toxicity.

215. Radiation-induced neuroinflammation: a potential protective role for poly(ADP-ribose) polymerase inhibitors?

216. A Novel Mechanism of Ataxia Telangiectasia Mutated Mediated Regulation of Chromatin Remodeling in Hypoxic Conditions.

217. Repurposing FDA approved drugs as radiosensitizers for treating hypoxic prostate cancer.

218. Data-driven mapping of hypoxia-related tumor heterogeneity using DCE-MRI and OE-MRI.

219. Novel carbonic anhydrase IX-targeted therapy enhances the anti-tumour effects of cisplatin in small cell lung cancer.

220. Akt inhibition improves long-term tumour control following radiotherapy by altering the microenvironment.

221. High-Affinity "Click" RGD Peptidomimetics as Radiolabeled Probes for Imaging α v β 3 Integrin.

222. Dissemination via the lymphatic or angiogenic route impacts the pathology, microenvironment and hypoxia-related drug response of lung metastases.

223. Detection of apoptosis by PET/CT with the diethyl ester of [¹⁸F]ML-10 and fluorescence imaging with a dansyl analogue.

224. Carbonic anhydrase IX as a target for metastatic disease.

225. GDC-0941 inhibits metastatic characteristics of thyroid carcinomas by targeting both the phosphoinositide-3 kinase (PI3K) and hypoxia-inducible factor-1α (HIF-1α) pathways.

226. Overexpression of cytochrome P450 NADPH reductase sensitises MDA 231 breast carcinoma cells to 5-fluorouracil: possible mechanisms involved.

227. Viral delivery of P450 reductase recapitulates the ability of constitutive overexpression of reductase enzymes to potentiate the activity of mitomycin C in human breast cancer xenografts.

228. Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor.

229. Metabolic changes detected by in vivo magnetic resonance studies of HEPA-1 wild-type tumors and tumors deficient in hypoxia-inducible factor-1beta (HIF-1beta): evidence of an anabolic role for the HIF-1 pathway.

230. A protective role for HIF-1 in response to redox manipulation and glucose deprivation: implications for tumorigenesis.

231. Antiangiogenic, bioreductive and gene therapy approaches to the treatment of hypoxic tumours.

232. The effectiveness of contingency-planning counseling.

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