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453. A quest for questions: The JUSTRA as a matrix for navigating just food system transformations in an era of uncertainty

455. Rapid and relaying deleterious effects of a gastrointestinal pathogen, Citrobacterrodentium, on bone, an extra-intestinal organ

458. European distribution and intramuscular pathogenicity of divergent lyssaviruses West Caucasian bat virus and Lleida bat lyssavirus

459. Noncoding variants and sulcal patterns in congenital heart disease: Machine learning to predict functional impact

460. Pathogenic KIAA0586/TALPID3 variants are associated with defects in primary and motile cilia

462. Multi-modal biosensing enabled by on-chip nano-corrugated graphene

464. Rhodoquinone carries electrons in the mammalian electron transport chain

465. Global organelle profiling reveals subcellular localization and remodeling at proteome scale

468. Hyperacute rejection-engineered oncolytic virus for interventional clinical trial in refractory cancer patients

469. An engineered cereblon optimized for high-throughput screening and molecular glue discovery

470. Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease

473. Serum free light chains in a racially diverse population including African Americans and populations from South Africa

474. Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy

475. A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion

478. A genome-wide association study identified PRKCB as a causal gene and therapeutic target for Mycobacterium avium complex disease

479. Disrupting AGR2/IGF1 paracrine and reciprocal signaling for pancreatic cancer therapy

481. Correlation of PSA and survival in metastatic hormone-sensitive prostate cancer treated with rezvilutamide plus ADT in the CHART trial

484. 2D covalent organic framework via catenation

485. Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation

486. Long-term 3-year follow-up of mosunetuzumab in relapsed or refractory follicular lymphoma after ≥2 prior therapies

488. Chromosome-scale genome assembly reveals how repeat elements shape non-coding RNA landscapes active during newt limb regeneration

489. NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression

490. Recirculating regulatory T cells mediate thymic regeneration through amphiregulin following damage

491. Bi-directional communication between intrinsic enteric neurons and ILC2s inhibits host defense against helminth infection

493. Congenital T-cell activation impairs transitional-to-follicular B-cell maturation in humans

494. Clonal hematopoiesis in patients with autoimmune thrombocytopenia: an international multicenter study

495. Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

497. A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer

499. CIROZ is dispensable in ancestral vertebrates but essential for left-right patterning in humans

500. Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood

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