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345 results on '"Zhang, Xianzheng"'

17. Characteristics and risk assessment of debris flows in the Wandong catchment after the MS 6.8 Luding earthquake

Author

ZHANG Xianzheng, TIE Yongbo, LI Guanghui, YANG Chang, LU Jiayan, and LU Tuo

Subjects
luding earthquake, post-earthquake debris flow, co-seismic landslides, outburst amplification, risk prediction, Geology, QE1-996.5
Abstract

On Sep. 5, 2022, an MS 6.8 earthquake struck Luding County. The earthquake triggered large amounts of co-seismic landslides, which blocked the Wandong River for nearly 24 hours. Field surveys, image interpretation, spatial statistics, and hydro-logical calculations were used to investigate the characteristics of co-seismic landslides and the risk of debris flow following the earthquake. According to the findings, co-seismic landslides are primarily found in areas of earthquake intensity IX, and their sizes are typically small and medium. They are distributed along both sides of the channel, particularly on both sides of the thin ridge facing the air. The distance from the fault and slope controls the distribution of co-seismic landslides. The volume of debris flow runout in the Wandong catchment may be twice that of the debris flow prior to the earthquake. On this basis, the following disaster prevention and mitigation suggestions were put forward. The risk of runout debris flow in the catchment should be strengthened; The value of triggering rainfall of debris flow should be obtained as soon as possible through comprehensive monitoring and early warning; The scale amplification factor of debris flow should be fully considered in the design of debris flow prevention and control projects. This research can be used as a scientific reference for disaster prevention and mitigation of post-earthquake debris flows.

Published
2022
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18. Research on the pattern of typical geohazard chains in the southwest mountainous region, China

Author

TIE Yongbo, ZHANG Xianzheng, GONG Lingfeng, GAO Yanchao, BAI Yongjian, XU Wei, BA Renji, LI Zongliang, and GE Hua

Subjects
southwest mountainous region, geohazard chain, hazard-inducing mechanism, transboundary basin, risk control, Geology, QE1-996.5
Abstract

The southwest mountainous region in China is the worst-hit area due to the most developed geohazard chains. In order to better understand the pattern of the geohazard chains in this region, we analyzed the main control factors and characteristics of the geohazard chains based on 19 typical geohazard events in history. Three classification patterns, namely landslide-type, collapse-type, debris flow-type, and five typical hazard-inducing processes, were summarized. A typical hazard-inducing chain process in each model was selected for analysis. On this basis, we discussed the mechanism of the geohazard chain, the construction of a database and technical standard system, and the measures for preventing and controlling transboundary basin chain-type geohazards, aiming to provide a reference for the regional geohazard prevention and mitigation plan, and the major engineering projects' construction and people's safety in town.

Published
2022
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19. Characteristics of geological hazards and it’s mitigations of the Ms6.8 earthquake in Luding County, Sichuan Province

Author

TIE Yongbo, ZHANG Xianzheng, LU Jiayan, LIANG Jingtao, WANG Donghui, MA Zhigang, LI Zongliang, LU Tuo, SHI Shengwei, LIU Minsheng, BA Renji, HE Longjiang, ZHANG Xinke, GAN Wei, CHEN Kai, GAO Yanchao, BAI Yongjian, GONG Lingfeng, ZENG Xiaowen, and XU Wei

Subjects
ms 6.8 earthquake in luding county, co-seismic geological hazards, hazard control conditions, evolution trend, hazard mitigation countermeasures, Geology, QE1-996.5
Abstract

On September 5th, 2022, the Ms 6.8 earthquake in Luding County, Sichuan Province induced large numbers of geological hazards. In order to deeply understand the evolution, distribution, and characteristics of geological hazards caused by the earthquake, we obtained the distribution of geological hazards by the field investigation and remote sensing interpretation. The conditions for hazard control and the countermeasures for hazard prevention and reduction are also analyzed. The results show that as of 22:00 on September 14, 2022, the earthquake has induced 565 geological hazards with threat objects in Luding County and Shimian County (including 331 collapses and 234 landslides), and 81 existing geological hazards whose deformation increased. The geological hazards induced by the earthquake are mainly medium and small mass high-level collapses, which are mainly concentrated in the areas with Seismic intensity zone of Ⅸ near the epicenter. These areas include Moxi Town, Detuo Township, both banks of Dadu River between Detuo Township and Dewei town in Luding County, Caoke Township and Wanggangping Township in Shimian County. According to the experience of the Wenchuan earthquake, the debris flow will be active in the next five years, and its characteristics of high frequency and viscous debris flow should be considered in the design of debris flow prevention and control engineering. Under the rainfall condition, the landslide deposition remaining on the slopes of Dadu River banks in the section of Detuo Township—Dewei Town can easily transform into debris flow. The transformation forms of the two hazards’ types should be fully considered in the design of prevention and control projects. The study can provide a reference for earthquake geological hazard prevention and post hazard reconstruction planning in the earthquake area.

Published
2022
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37. Advanced Strategies for Strengthening the Immune Activation Effect of Traditional Antitumor Therapies

Author

Ning, Jingyi, Lu, Xinxin, Dong, Jianhui, Xue, Chun, Ou, Changjin, Zhang, Yizhou, Zhang, Xianzheng, and Gao, Fan

Abstract

The utilization of traditional therapies (TTS), such as chemotherapy, reactive oxygen species-based therapy, and thermotherapy, to induce immunogenic cell death (ICD) in tumor cells has emerged as a promising strategy for the activation of the antitumor immune response. However, the limited effectiveness of most TTS in inducing the ICD effect of tumors hinders their applications in combination with immunotherapy. To address this challenge, various intelligent strategies have been proposed to strengthen the immune activation effect of these TTS, and then achieve synergistic antitumor efficacy with immunotherapy. These strategies primarily focus on augmenting the tumor ICD effect or facilitating the antigen (released by the ICD tumor cells) presentation process during TTS, and they are systematically summarized in this review. Finally, the existing bottlenecks and prospects of TTS in the application of tumor immune regulation are also discussed.

Published
2024
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42. Precise nanomedicine for intelligent therapy of cancer

Author

Chen, Huabing, Gu, Zhanjun, An, Hongwei, Chen, Chunying, Chen, Jie, Cui, Ran, Chen, Siqin, Chen, Weihai, Chen, Xuesi, Chen, Xiaoyuan, Chen, Zhuo, Ding, Baoquan, Dong, Qian, Fan, Qin, Fu, Ting, Hou, Dayong, Jiang, Qiao, Ke, Hengte, Jiang, Xiqun, Liu, Gang, Li, Suping, Li, Tianyu, Liu, Zhuang, Nie, Guangjun, Ovais, Muhammad, Pang, Daiwen, Qiu, Nasha, Shen, Youqing, Tian, Huayu, Wang, Chao, Wang, Hao, Wang, Ziqi, Xu, Huaping, Xu, Jiang-Fei, Yang, Xiangliang, Zhu, Shuang, Zheng, Xianchuang, Zhang, Xianzheng, Zhao, Yanbing, Tan, Weihong, Zhang, Xi, and Zhao, Yuliang

Published
2018
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44. GRK2 Mediates Macrophage Polarization by Regulating EP4-cAMP-pCREB Signaling in Ulcerative Colitis and the Therapeutic Effect of Paroxetine on Mice with DSS-Induced Colitis

Author

Zhang, Jiawei, primary, Zhang, Xianzheng, additional, Lu, Mingdian, additional, Chang, Yan, additional, Wang, Qingtong, additional, Tu, Jiajie, additional, Wu, Huaxun, additional, Wang, Chun, additional, Hong, Zhongyang, additional, Xiong, Maoming, additional, Song, Lihua, additional, and Wei, Wei, additional

Published
2023
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45. Comparative Study About Different Doses of Remimazolam in Short Laparoscopic Surgery: A Randomized Controlled Double-Blind Trial

Author

Luo,Li, Jiang,Jiduan, Zhang,Min, Guo,Zhiqiang, Zhang,Xianzheng, Wang,Fenglin, Yang,Fan, Luo,Li, Jiang,Jiduan, Zhang,Min, Guo,Zhiqiang, Zhang,Xianzheng, Wang,Fenglin, and Yang,Fan

Abstract

Li Luo,1 Jiduan Jiang,2 Min Zhang,1 Zhiqiang Guo,1 Xianzheng Zhang,1 Fenglin Wang,1 Fan Yang1 1Department of Anesthesiology, Suining Central Hospital, Suining City, Sichuan Province, People’s Republic of China; 2Department of Anesthesiology, Suining First People’s Hospital, Suining City, Sichuan Province, People’s Republic of ChinaCorrespondence: Fan Yang, Department of Anesthesiology, Suining Central Hospital, Suining City, Sichuan Province, 629000, People’s Republic of China, Email yanglifan2@163.comObjective: To study the efficacy and safety of different doses of remimazolam used for induction and maintenance in short laparoscopic surgery.Methods: A randomized controlled trial was conducted between May 2021 and May 2022 on patients underwent laparoscopic surgery for 30 minutes to an hour. Based on the drug used and the infusion rate, included patients were allocated into the Low-group of remimazolam (using a constant infusion rate of 6.0 mg/kg/h for induction and the rate of 1 mg/kg/h for maintenance), the Median-group (9.0 mg/kg/h for induction, 2 mg/kg/h for maintenance), the High-group (12.0 mg/kg/h for induction, 3.0 mg/kg/h for maintenance), and the Propofol group. The postoperative extubation time was used as the primary outcome.Results: A total of 192 patients were included in the study, with 47, 48, 48, and 49 patients in the Low-, Median-, High-, and Propofol group, respectively. There was a significant difference in postoperative extubation time, with the High-group having the highest duration of 15.21± 2.34 minutes compared to the Median-group (13.17± 1.71 minutes, p< 0.001), Low- group (12.72± 1.31 minutes, p< 0.001), and the Propofol group (12.24± 1.23 minutes, p< 0.001). No significant difference was found between the Low-group and the Propofol group, while the Median-group still showed higher postoperative extubation time compared to the Propofol group (p=0.008).Conclusion: Compared to propofol, total intravenous induction and

Published
2023

47. The complete mitochondrial genome of Nycteribia formosana (Diptera, Nycteribiidae).

Author

Zheng, Xiaoyan, Huang, Xiaobin, Yang, Jinting, Yang, Huijuan, and Zhang, Xianzheng

Subjects
MITOCHONDRIAL DNA, DIPTERA, TRANSFER RNA, RIBOSOMAL RNA, GENETIC transformation, SPECIES, BATS
Abstract

The family Hippoboscidae is an ectoparasite that primarily inhabits bats and relies on the host's blood for sustenance. This research provides the first complete mitochondrial genome of Nycteribia formosana, which shares similar characteristics with other dipteran insects. The circularized mitochondrial genome, spanning 15,107 bp, encompasses 13 protein-coding genes (PCGs), 22 transfer RNA genes (tRNA), two ribosomal RNA genes, and a control region. The nucleotide composition of A, C, G, and T is 40.4%, 10.9%, 6.7%, and 42.0%, respectively. The findings from the phylogenetic analysis suggest that the species under investigation forms a cluster with other species belonging to the family Nycteribiidae. Consequently, this study provides valuable insights for the identification of N. formosana. [ABSTRACT FROM AUTHOR]

Published
2023
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