226 results on '"Sandow, Jarrod J."'
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2. Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
3. SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia
4. Mapping the IMiD‐dependent cereblon interactome using BioID‐proximity labelling.
5. Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies
6. Multimodal regulation of encystation in Giardia duodenalis revealed by deep proteomics
7. Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling
8. The regulation of necroptosis by post-translational modifications
9. Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models
10. Identification of novel interacting partners of the NEDD4 ubiquitin ligase in mouse testis
11. Phosphorylation by Aurora B kinase regulates caspase-2 activity and function
12. Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis
13. Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix
14. Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis
15. BAK core dimers bind lipids and can be bridged by them
16. Dynamic reconfiguration of pro‐apoptotic BAK on membranes
17. Autophagy captures the retromer-TBC1D5 complex to inhibit receptor recycling.
18. Autophagy captures the retromer-TBC1D5 complex to inhibit receptor recycling
19. A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis
20. Structure of Plasmodium falciparum Rh5–CyRPA–Ripr invasion complex
21. It takes two to tango: structure of viral kinase PK-1 reveals a new mode of kinase regulation
22. A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma
23. Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues
24. Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte
25. Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted
26. Data from CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory
27. TableS1.xlsx from CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory
28. Supplementary Figures from CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory
29. Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy
30. CD98 defines a metabolically flexible, proinflammatory subset of low‐density neutrophils in systemic lupus erythematosus
31. VDAC2 enables BAX to mediate apoptosis and limit tumor development
32. Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain
33. Signalling by the βc family of cytokines
34. Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death
35. K‐29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis
36. The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs
37. Arrdc4‐dependent extracellular vesicle biogenesis is required for sperm maturation
38. The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
39. Proteomic analyses reveal that immune integrins are major targets for regulation by Membrane‐Associated Ring‐CH (MARCH) proteins MARCH2, 3, 4 and 9
40. CDK4/6 Inhibition Promotes Antitumor Immunity through the Induction of T-cell Memory
41. Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
42. How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor
43. Cp1/cathepsin L is required for autolysosomal clearance in Drosophila
44. Tankyrase-mediated ADP-ribosylation is a novel regulator of TNF-induced death
45. The search for RNA-binding proteins: a technical and interdisciplinary challenge
46. Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death.
47. Cp1/cathepsin L is required for autolysosomal clearance in Drosophila
48. Phosphorylation by Aurora B kinase regulates caspase-2 activity and function
49. A PP2A-Integrator complex fine-tunes transcription by opposing CDK9
50. How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor
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