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1. Building Timely Consensus Among Diverse Stakeholders: An Adapted Nominal Group Technique

Author

Cetin-Sahin, Deniz, Arsenault-Lapierre, Genevieve, Bolster-Foucault, Clara, Champoux-Pellegrin, Juliette, Rojas-Rozo, Laura, Quesnel-Vallee, Amelie, and Vedel, Isabelle

Subjects
Research, Methods, Primary health care -- Research -- Methods
Abstract

INTRODUCTION The participatory research approach is an important tool for family medicine and primary health care research. (1) By recognizing stakeholders' expertise and lived experiences, (2) this approach increases the [...], PURPOSE Building timely consensus among diverse stakeholders is important in primary health care research. Consensus can be obtained using the nominal group technique which includes 5 steps: (1) introduction and explanation; (2) silent generation of ideas; (3) sharing ideas; (4) discussion; and (5) voting and ranking. The main challenges in using this technique are a lack of representation of different stakeholder opinions and the amount of time taken to reach consensus. In this paper, we demonstrate how to effectively achieve consensus using an adapted nominal group technique that mitigates the challenges. METHODS This project aimed to reach consensus on the priority care domains for individuals aged 65 or older, using an adapted nominal group technique with 4 strategies: (1) recruit 4 stakeholders groups (older people, clinicians, managers, decision makers) by using maximum variation and snowballing sampling approaches; (2) use remote tools to ensure high participation; (3) add an individual pre-elicitation activity to increase effectiveness; and (4) adapt discussions to the stakeholders' preferences for meaningful engagement. RESULTS In total, 28 diverse stakeholders participated. After the pre-elicitation activity and 1 round of group discussion, we reached consensus on a priority domain called symptoms, functioning, and quality of care. Adaptive group discussions and remote tools were the most effective strategies. All participants strongly agreed that they were able to express their views freely. Some perceived a need for emphasizing the alignment between the research objectives and anticipated practice and policy implications. CONCLUSIONS This adapted nominal group technique is an effective and enriching method when timely consensus is needed among diverse stakeholders. Health care researchers in various fields can benefit from using this research methodology.

Published
2024
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9. The COVID-19 Pandemic and Dementia: a Multijurisdictional Meta-Analysis of the Impact of the First Two Pandemic Waves on Acute Health-care Utilization and Mortality in Canada.

Author

Cetin-Sahin, Deniz, Godard-Sebillotte, Claire, Bronskill, Susan E., Seitz, Dallas, Morgan, Debra G., Maclagan, Laura C., Sourial, Nadia, Quail, Jacqueline, Gruneir, Andrea, Wilchesky, Machelle, Rochette, Louis, Massamba, Victoria Kubuta, Youngson, Erik, Diong, Christina, Smith, Eric E., Arsenault-Lapierre, Geneviève, Le Berre, Mélanie, Maxwell, Colleen J., Kosteniuk, Julie, and Bosson-Rieutort, Delphine

Abstract

Background: Previous studies on the impact of the coronavirus disease 2019 (COVID-19) pandemic on persons living with dementia (PLWD) were mostly conducted in a single jurisdiction or focused on a limited number of outcomes. Our study estimates the impact of the first two pandemic waves on emergency department (ED) visits (all-cause/ambulatory care sensitive conditions), hospitalizations (all-cause/30-day readmissions), and all-cause mortality in four Canadian jurisdictions. Methods: Using administrative databases from Alberta, Ontario, Saskatchewan, and Quebec, we assembled two closed retrospective cohorts (2019/pre-pandemic control and 2020/pandemic) of PLWD aged 65+. Within community and nursing home settings, the rates of the above-mentioned outcomes in three pandemic periods (first wave, interim period, second wave) were compared to the corresponding pre-pandemic periods. We performed random effects meta-analyses on the provincial incident rate ratios. Results: Pre-pandemic and pandemic cohorts included 167,095 vs. 173,240 (community) and 93,374 vs. 92,434 (nursing home) individuals, respectively. During the first wave, community and nursing home populations experienced significant declines in the rates of all-cause ED visits (36% vs. 40%) and hospitalizations (25% vs. 22%), which persisted in the following periods in the community. These declines were greater for the rates of ambulatory care sensitive condition ED visits and 30-day readmissions. Mortality was 36% higher in nursing homes (first wave) and 13% higher in the community (second wave). Conclusions: It is key to prepare for future health crises and ensure that PLWD receive necessary care and services and do not have such a high mortality rate. Attention should be equally given to PLWD living in their homes and nursing homes. [ABSTRACT FROM AUTHOR]

Published
2025
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10. Virtual primary care for people living with dementia in Canada: cross-sectional surveys of patients, care partners, and family physicians.

Author

Khanassov, Vladimir, Cetin-Sahin, Deniz, Feldman, Sid, Sivananthan, Saskia, Grill, Allan, and Vedel, Isabelle

Subjects
*SENILE dementia treatment, *HEALTH services accessibility, *CROSS-sectional method, *MEDICAL care use, *STATISTICAL models, *RESEARCH funding, *RECEIVER operating characteristic curves, *PRIMARY health care, *QUESTIONNAIRES, *LOGISTIC regression analysis, *PHYSICIANS' attitudes, *DESCRIPTIVE statistics, *WAGES, *CHI-squared test, *TELEMEDICINE, *THEMATIC analysis, *ODDS ratio, *CONFIDENCE intervals, *FAMILY support, *NEEDS assessment, *DEMENTIA patients, *CAREGIVER attitudes, *PATIENTS' attitudes
Abstract

Background: Virtual care (VC) for dementia in primary care settings is an important aspect of healthcare delivery in Canada. However, the evidence informing optimal and sustainable provision of VC for persons living with dementia (PLWD) and their care partners is scarce. The objectives of this study were to (1) describe the frequency of VC use, (2) identify characteristics of PLWD, care partners, and family physicians (FPs) that are associated with the use of VC, and (3) explore FPs' perceptions of barriers and facilitators to provide VC for PLWD and their care partners. Methods: The Alzheimer Society of Canada and College of Family Physicians of Canada conducted three nationwide cross-sectional surveys between October 2020 and April 2021: (1) One with PLWD, (2) one with care partners of PLWD, and (3) one with FPs. Virtual care was defined as two-way synchronous communication by telephone and/or a web camera. The prevalence of VC use among FPs, PLWD, and care partners was described. Logistic regression models were used to determine characteristics of participants (sociodemographic, urbanicity, frequency and availability of support for connecting with FPs, and FPs' practice characteristics) associated with any VC use (phone and/or video). Inductive thematic analysis of open-ended questions explored FPs' perceptions. Results: 131 PLWD, 341 care partners, and 125 FPs participated. 61.2% of PLWD, 59.5% of care partners, and 77.4% of FPs reported using VC. The models for PLWD (included age and ethnicity) and care partners (included gender/sex, urbanicity, and receiving support from a family member/friend to connect with FP) were inconclusive. FPs with > 20 years in practice were less likely to provide VC (OR = 0.23, 95%CI: 0.08–0.62, p < 0.01). FPs perceived that preferences regarding virtual vs. in-person care, office/family support, technology and family presence, and remuneration for FPs influenced VC use. Conclusions: Virtual primary dementia care uptake in Canada is substantial and mainly performed via telephone. According to FPs, physician-patient-caregiver partnerships and infrastructure for VC play key roles in using VC. Virtual care could facilitate access to primary care and minimize potential disruptions to in-person care for PLWD. Outcomes of virtual primary care for dementia need further investigation. [ABSTRACT FROM AUTHOR]

Published
2025
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14. Clinical characteristics and therapeutic outcomes of paroxysmal nocturnal hemoglobinuria patients in Turkey: a multicenter experience

Author

Goren Sahin, Deniz, Akay, Olga Meltem, Keklik, Muzaffer, Okan, Vahap, Karakus, Abdullah, Demir, Cengiz, Erkurt, Mehmet Ali, Ilkkilic, Kadir, Yildirim, Rahsan, Akgun Cagliyan, Gulsum, Aksu, Salih, Dogu, Mehmet Hilmi, Dal, Mehmet Sinan, Karakus, Volkan, Gemici, Ali Ihsan, Terzi, Hatice, Kelkitli, Engin, Sivgin, Serdar, Unal, Ali, Yilmaz, Mehmet, Ayyildiz, Orhan, Korkmaz, Serdal, Eser, Bulent, and Altuntas, Fevzi

Published
2021
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15. Identification of Peptides Binding Specifically to Colon Cancer Cells through Phage Display Peptide Library Screening.

Author

Sahin, Deniz, Kanlidere, Zeynep, Ekal, Bariscan, Abayli, Berkehur, Hayat, Yordan, and Selcuk, Ece

Subjects
COLON cancer, AMINO acid analysis, COLON cancer diagnosis, RECTAL cancer, COLORECTAL cancer
Abstract

Objective: Colorectal cancer ranks among the most frequently occurring cancers. Addressing the diagnosis and treatment challenges requires the advancement of alternative approaches that can more precisely differentiate between cancerous and healthy cells. Materials and Methods: We identified colon cancer cell surface specific 12-mer peptides using subtractive phage display technique. Four rounds of biopanning were conducted using the M13 bacteriophage PhD-12 peptide library with the human colon cancer cell line HCT-116. Subtractive selection involved the use of the human rectal cancer cell line SW837 and the healthy CCD112-CoN cell line. Binding levels of selected phage clones were tested by ELISA-HRP binding assays. Experimentally identified peptide sequences were synthesized by solid-phase chemistry. Peptides were labelled at the N-terminus with a fluorescent dye for visualization of cells by confocal microscopy. Results: Peptide COL419 (Serine-Valine-Alanine-Histidine-Leucine-Serine-Proline-Histidine-Serine-Threonine-Threonine-Alanine; SVAHLSPHSTTA) can differentiate colon and rectal cancers from healthy cells. In addition, the COL-AA peptide (Histidine-Tyrosine-ProlineThreonine-Asparagine-Leucine-Histidine-Tyrosine-Proline-Threonine-Asparagine-Leucine; HYPTNLHYPTNL), which was designed from the amino acid composition analysis of the experimentally selected peptide sequences bound to colon cancer cells and neither rectal cancer cells nor healthy colorectal cells. Conclusion: The peptides determined specifically target colon cancer cells. These findings enhance our understanding of the differences between these cancer types. The selected peptides have the potential for clinical application in targeted diagnosis and treatment of colon cancer. [ABSTRACT FROM AUTHOR]

Published
2024
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17. The Turkish experience with therapeutic plasma exchange: A national survey

Author

Korkmaz, Serdal, Solmaz Medeni, Serife, Demirkan, Fatih, Kalayoglu Besisik, Sevgi, Altay Dadin, Senem, Akgun Cagliyan, Gulsum, Kabukcu Hacioglu, Sibel, Sari, Ismail, Goren Sahin, Deniz, Arat, Mutlu, Dagdas, Simten, Ozet, Gulsum, Kutlu, Nermin, Karaagac Akyol, Tulay, Ozcebe, Osman Ilhami, Uskudar Teke, Hava, Kiper Unal, Demet, Guner, Naile, Tombak, Anil, Celik, Halil, Bay, Ilker, Kiki, Ilhami, Ozgur, Gokhan, Erkurt, Mehmet Ali, Ozatli, Duzgun, Meletli, Ozgur, Demircioglu, Sinan, Demir, Cengiz, Kurtoglu, Erdal, Vural, Filiz, Tobu, Mahmut, Karakus, Abdullah, Ayyildiz, Orhan, Dal, Mehmet Sinan, Afacan Ozturk, Berna, Albayrak, Murat, Ocakci, Serkan, Bolaman, Zahit, Sonmez, Mehmet, Karakus, Volkan, Gokmen Sevindik, Omur, Berber, Ilhami, Dogu, Mehmet Hilmi, Gulturk, Emine, Ulas, Turgay, Payzin, Bahriye, Kuku, Irfan, Cagirgan, Seckin, and Altuntas, Fevzi

Published
2019
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20. Prognostic value of end-of-induction PET response after first-line immunochemotherapy for follicular lymphoma (GALLIUM): secondary analysis of a randomised, phase 3 trial

Author

Hertzberg, Mark, Grigg, Andrew, Cannell, Paul, Quach, Hang, Opat, Stephen, Tam, Constantine, Marlton, Paula, Janssens, Ann, Offner, Fritz, Van eygen, Koen, Sangha, Randeep, Mckay, Pam, Wilson, Jonathan, Van Der Jagt, Richard, Roitman, Daryl, Trneny, Marek, Mayer, Jiri, Le Du, Katell, Solal-Celigny, Philippe, Cartron, Guillaume, Foussard, Charles, Frickhofen, Norbert, Schmidt, Peter, Graeven, Ullrich, Gaska, Tobias, Schlag, Rudolf, Sökler, Martin, Prange-Krex, Gabriele, Florschütz, Axel, Lindemann, Hans-Walter, Schimmelpfennig, Christoph, Tonndorf, Solveig, Hänel, Mathias, Hess, Georg, Schalk, Enrico, Hütten, Heiko, Doelken, Gottfried, Pfreundschuh, Michael, Keller, Ulrich, Herold, Michael, Forstpointner, Roswitha, Vehling-Kaiser, Ursula, Hoffmann, Martin, Borbenyi, Zita, Udvardy, Miklos, Demeter, Judit, Rambaldi, Alessandro, Morra, Enrica, Massimo, Federico, Majolino, Ignazio, Balzarotti, Monica, Semenzato, Gianpietro, Canales Albendea, Miguel Angel, Peñalver Parraga, Francisco Javier, Soler Campos, Alfonso, Sancho Cia, Juan Manuel, Marquez Navarro, Jose Antonio, Grande Garcia, Carlos, Nilsson-Ehle, Herman, Mccarthy, Helen, Pocock, Chris, Sadullah, Shalal, Malladi, Ram, Radford, John, Kanfer, Ed, Kruger, Anton, Culligan, Dominic, Dyer, Martin, Pettengell, Ruth, Seymour, John, Gribben, John, Al-Ismail, Saad, Al-Refaie, Faris, Blesing, Norbert, Macnamara, Christopher, O'callaghan, Ann, Haynes, Andrew, Follows, George, Johnson, Roderick, Cunningham, David, Bowles, Kristian, Collins, Graham, Gallop-Evans, Eve, Robinson, Stephen, Subash, Chezhian, Bailey, James, Holden, Viran, Neidhart, Jeffrey, De Oliveira, Moacyr, Tezcan, Haluk, Kim, Kevin, Kambhampati, Suman, Lanier, Keith, Mcclean, John, Tobinai, Kensei, Hatake, Kiyohiko, Ogura, Michinori, Uchida, Toshiki, Ando, Kiyoshi, Kinoshita, Tomohiro, Höhler, Thomas, Stauder, Heribert, Kirsch, Andreas, Koenigsmann, Michael, Kremers, Stephan, Illmer, Thomas, Witzens-Harig, Mathias, La Roseé, Paul, Dürig, Jan, Kneba, Michael, Hensel, Manfred, Fuxius, Stefan, Bergmann, Lothar, Hübel, Kai, Buske, Christian, Marks, Reinhard, Wulf, Gerald, Lerchenmueller, Christian, Schmits, Rudolf, Reinwald, Mark, Lengfelder, Eva, Scott, Fiona, Chou, Takaaki, Taniwaki, Masafumi, Yoshida, Isao, Ishizawa, Kenichi, Uike, Naokuni, Uoshima, Nobuhiko, Kamitsuji, Yuri, Iida, Shinsuke, Ohmine, Ken, Nosaka, Kisato, Ide, Kazuhiko, Ishikawa, Takayuki, Desjardins, Pierre, Finn, Nicholas, Zhu, Jun, Li, Wei, Yu, Li, Ren, Hanyun, Shi, Yuan Kai, Wu, Gang, Hong, Xiaonan, Zhang, Qingyuan, Feng, Jifeng, Zhan, Rong, Lin, Tongyu, Leppa, Sirpa, Costello, Regis, Tempescul, Adrian, Sanhes, Laurence, Tournilhac, Olivier, Kirchen, Heinz, Hebart, Holger, Weide, Rudolf, Jentsch-Ullrich, Kathleen, Avivi, Irit, Nagler, Arnon, Gurion, Ronit, Shpilberg, Ofer, Leoni, Pietro, Baldini, Luca, Samoylova, Olga, Myasnikov, Alexandr, Tan, Tran-Der, Chang, Hung, Kumagai, Kyoya, Tsukamoto, Norifumi, Tsukasaki, Kunihiro, Beatty, Patrick, Usui, Noriko, Izutsu, Koji, Murayama, Tohru, Ichinohe, Tatsuo, Kubo, Kohmei, Ishida, Fumihiro, Beck, J. Thaddeus, Griesinger, Frank, Osmanov, Dzhelil, Dakhil, Shaker, Clavert, Aline, Maruyama, Dai, Terui, Yasuhito, Yamamoto, Kazuhito, Eigendorff, Ekkehard, Kobayashi, Tsutomu, Ichikawa, Satoshi, Choi, Ilseung, Wada, Katsuya, Kikukawa, Yoshitaka, Matsuoka, Masao, Yoshino, Takayuki, Minami, Yosuke, Trotman, Judith, Barrington, Sally F, Belada, David, Meignan, Michel, MacEwan, Robert, Owen, Carolyn, Ptáčník, Václav, Rosta, András, Fingerle-Rowson, Günter R, Zhu, Jiawen, Nielsen, Tina, Sahin, Deniz, Hiddemann, Wolfgang, Marcus, Robert E, and Davies, Andrew

Published
2018
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22. A comparison of the prognostic performance of the Lugano 2014 and RECIL 2017 response criteria in patients with NHL from the phase III GOYA and GALLIUM trials

Author

Kostakoglu, Lale, primary, Martelli, Maurizio, additional, Sehn, Laurie H., additional, Davies, Andrew, additional, Trněný, Marek, additional, Herold, Michael, additional, Vitolo, Umberto, additional, Hiddemann, Wolfgang, additional, Trotman, Judith, additional, Knapp, Andrea, additional, Mattiello, Federico, additional, Nielsen, Tina G., additional, Sahin, Deniz, additional, Sellam, Gila, additional, Ward, Carol, additional, and Younes, Anas, additional

Published
2023
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30. METHODS FOR ESTIMATING MULTIREGIONAL INPUT-OUTPUT-TABLES

Author

Sahin, Deniz and Sahin, Deniz

Abstract

Purpose – This report aims to address the methods used to obtain multi-regional input-output tables (MRIO-tables). Method – The research focuses on three gravity model of trade methods: simple gravity model estimation, doubly constrained gravity model estimation, and gravity model estimation with calibrated error function minimization. These methods are used for estimating and modelling multiregional trade flows, specifically in the context of MRIO-tables. These methods will be denoted as method 1, method 2 and method 3. Through a comparative analysis, the study focuses on the strengths and limitations of these methods and provides valuable insights for policymakers and researchers in the field. The findings contribute to a better understanding of the differences between the methods and their effectiveness in accurately representing MRIO-tables. Findings – This study evaluates three methods (mentioned above) for estimating multiregional trade flows, highlighting their performance. Method 1 and 2, exhibited similarities in their approach to estimating trade flows, both surpassing the performance of method 3 across various evaluation metrics. According to the results, method 1 and 2 are better than method 3 in accurately estimating multiregional trade flows. Limitations – This work had some limitations, the research focused on one specific product and how they flow between and across the regions as well as the total quantity of this product, i.e., the margins.

Published
2023

34. Supplementary Table S3 from Prognostic Impact of Natural Killer Cell Count in Follicular Lymphoma and Diffuse Large B-cell Lymphoma Patients Treated with Immunochemotherapy

Author

Klanova, Magdalena, primary, Oestergaard, Mikkel Z., primary, Trněný, Marek, primary, Hiddemann, Wolfgang, primary, Marcus, Robert, primary, Sehn, Laurie H., primary, Vitolo, Umberto, primary, Bazeos, Alexandra, primary, Goede, Valentin, primary, Zeuner, Harald, primary, Knapp, Andrea, primary, Sahin, Deniz, primary, Spielewoy, Nathalie, primary, Bolen, Christopher R., primary, Cardona, Andres, primary, Klein, Christian, primary, Venstrom, Jeffrey M., primary, Nielsen, Tina, primary, and Fingerle-Rowson, Günter, primary

Published
2023
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38. Key Healthcare Providers’ Perspectives on the Implementation of Senior-Friendly Emergency Department Care in Quebec

Author

Cetin-Sahin, Deniz, primary, Ducharme, Francine, additional, McCusker, Jane, additional, Magalhaes, Mona, additional, Veillette, Nathalie, additional, Lachance, Paul-André, additional, Cossette, Sylvie, additional, Vadeboncoeur, Alain, additional, Mah, Rick, additional, Vu, T.T. Minh, additional, and Berthelot, Simon, additional

Published
2022
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40. Measuring Potentially Avoidable Acute Care Transfers From Long-Term Care Homes in Quebec: a Cross Sectional Study.

Author

Cetin-Sahin, Deniz, Karanofsky, Mark, Cummings, Greta G., Vedel, Isabelle, and Wilchesky, Machelle

Subjects
HOSPITAL emergency services, CROSS-sectional method, TERTIARY care, HOSPITAL admission & discharge, COMPARATIVE studies, CRITICAL care medicine, HOSPITAL care of older people, DESCRIPTIVE statistics, RESEARCH funding, DATA analysis software, LONG-term health care
Abstract

Background Potentially avoidable emergency department transfers (PAEDTs) and hospitalizations (PAHs) from long-term care (LTC) homes are two key quality improvement metrics. We aimed to: 1) Measure proportions of PAEDTs and PAHs in a Quebec sample; and 2) Compare them with those reported for the rest of Canada. Methods We conducted a repeated cross-sectional study of residents who were received at one tertiary hospital between April 2017 and March 2019 from seven LTC homes in Quebec, Canada. The MedUrge emergency department database was used to extract transfers and resident characteristics. Using published definitions, PAEDTs and PAHs were identified from principal emergency department and hospitalization diagnoses, respectively. PAEDT and PAH proportions were compared to those reported by the Canadian Institute for Health Information. Results A total of 1,233 transfers by 692 residents were recorded, among which 36.3% were classified as being potentially avoidable: 22.8% 'PAEDT only', 11.6% 'both PAEDT & PAH', and 1.9% 'PAH only'. Shortness of breath was the most common reason for transfer. Pneumonia was the most common diagnosis from the 'both PAEDT & PAH' category. PAEDTs and PAHs accounted for 95% and 37% of potentially avoidable transfers, respectively. Among 533 hospitalizations, 31.3% were PAHs. These proportions were comparable to the rest of Canada, with some differences in proportions of transfers due to congestive heart failure, urinary tract infection, and implanted device management. Conclusions PAEDTs far outweigh PAHs in terms of frequency, and their monitoring is important for quality assurance as they may inform LTC-level interventions aimed at their reduction. [ABSTRACT FROM AUTHOR]

Published
2023
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42. Anti-inflammatory effects of montelukast on smoke-induced lung injury in rats

Author

Basyigit Ilknur, Sahin Murat, Sahin Deniz, Yildiz Fusun, Boyaci Hasim, Sirvanci Serap, and Ercan Feriha

Subjects
Chronic bronchitis, inflammation, montelukast, smoking, Diseases of the respiratory system, RC705-779
Abstract

Abstract Aim To evaluate the effects of montelukast in smoke-induced lung injury. Methods 28 Wistar-Albino rats were enrolled into 4 groups with 7 rats per group. The healthy control group was exposed to fresh air while all rats in the 3 experimental groups were exposed to cigarette smoke for 20 weeks for 2 hours per day. After histopathological verification of smoke induced lung injury, montelukast (0.1 mg/kg) dissolved in Na2CO3 was given in one group (MON), Na2CO3 only was given in another group (MON control) and placebo was injected in the third group (COPD control) intraperitoneally for 21 days. At the end of this period blood samples were obtained for serum TNF-α assessment and light and electron microscopy analyses were performed on the lung tissues of sacrificed rats. Results Serum TNF-α levels in the MON group were significantly lower than in the MON control and COPD control groups (38.84 ± 4.9 pg/ml, 77.5 ± 5.8 pg/ml and 79.2 ± 6.9 pg/ml respectively, p < 0.05). Furthermore there was no statistically significant difference between the MON group and healthy controls with respect to serum TNF-α levels (38.84 ± 4.9 pg/ml vs. 29.5 ± 3.6 pg/ml, p > 0.05). Light and electron microscopic evaluation of the lungs demonstrated that the total histopathological damage score of the lung samples was significantly lower in the MON group than in MON controls and COPD controls (5.14 ± 0.5, 8.4 ± 0.6 and 8.7 ± 0.4 respectively, p < 0.05), while there was no significant difference between the MON group and healthy controls (5.1 ± 0.6 vs 2.3 ± 0.2, p > 0.05). Conclusion These findings suggest that montelukast might have a protective effect on smoke-induced lung injury in rats both from a histopathological and inflammatory point of view.

Published
2010
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44. Analysis of peripheral neuropathy (PN) using clinician- and patient-reported outcomes (ClinRO and PRO) in the POLARIX study.

Author

Trneny, Marek, primary, Fogliatto, Laura, additional, Gardner, Faithlore Patrice, additional, Flinn, Ian W., additional, Larouche, Jean-Francois, additional, Haioun, Corinne, additional, Canales Albendea, Miguel Angel, additional, Goto, Hideki, additional, Hajek, Roman, additional, Salles, Gilles A., additional, Qiu, Jiaheng, additional, Campinha-Bacote, Avrita, additional, Yan, Mark, additional, Kothari, Rucha, additional, Man, Gabriel, additional, Sahin, Deniz, additional, Hirata, Jamie, additional, Lee, Calvin, additional, Tilly, Herve, additional, and Flowers, Christopher, additional

Published
2022
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45. THE EFFECTS OF ABDOMINAL BRACING MANEUVER ON QUADRICEPS MUSCLE TORQUE, TIME TO PEAK TORQUE AND MUSCLE ACTIVATION LEVELS AT DIFFERENT KNEE FLEXION ANGLES

Author

HARPUT, GÜLCAN, Yilli, Sercan, Sogut, Bensu, Tarkan, Sumeyya, Sahin, Deniz Can, and Arslan, Damla

Abstract

Purpose: The aim of the present study was to investigate the effects of abdominal bracing maneuver (ABM) on quadriceps peak torque (PT), time to peak torque (TTPT) and muscle activation levels during maximal strength testing of the quadriceps muscle in healthy individuals. Methods: Sixteen healthy individuals (Age: 24.63 +/- 1.67 years) participated in the present study. Each participant was taught ABM technique by a physical therapist's guidance. Surface electromyography was used to measure internal oblique/transversus abdominis, vastus medialis, vastus lateralis, and rectus femoris activation levels. Isokinetic dynamometry was used to measure quadriceps PT and TTPT during maximum isometric muscle testing at 60 degrees and 90 degrees of knee flexion angles with and without ABM. Repeated measures of ANOVA was performed for statistical analysis. Results: There was a significant angle by condition interaction for quadriceps PT (F(1,15)=5.30, p=0.04). PT decreased when ABM was performed, but the decrease was greater at 600 compared to 900 of knee flexion (60 degrees: p=0.001, ES=0.68; 90 degrees: p=0.008, ES=0.33). Quadriceps activation levels also decreased during ABM (p=0.04) regardless of knee flexion angle. Conclusion: The present study revealed that ABM may decrease muscle activation levels and peak torque during maximal quadriceps strength testing. Researchers should evaluate compensatory movements of the lumbopelvic region in order to prevent the error of force transfer in test results.

Published
2022

48. A prognostic model integrating PET‐derived metrics and image texture analyses with clinical risk factors from GOYA

Author

Kostakoglu, Lale, primary, Dalmasso, Federico, additional, Berchialla, Paola, additional, Pierce, Larry A., additional, Vitolo, Umberto, additional, Martelli, Maurizio, additional, Sehn, Laurie H., additional, Trněný, Marek, additional, Nielsen, Tina G., additional, Bolen, Christopher R., additional, Sahin, Deniz, additional, Lee, Calvin, additional, El‐Galaly, Tarec Christoffer, additional, Mattiello, Federico, additional, Kinahan, Paul E., additional, and Chauvie, Stephane, additional

Published
2022
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50. Geriatric dementia care at Ontario Shores: A new model of care

Author

Viau, Katelynn, Yaddaden, Amel, Lussier, Maxime, Bier, Nathalie, Earle, Julie, Duff-Woskosky, Andra, Bartfay, Wally, Desai, Chaitali, Zavitz, Karen, Horsburgh, Sheri, Gamble, Brenda, Lee, Linda, Hillier, Loretta M., Patel, Tejal, Molnar, Frank, Clarke, Jo-Anne, Borrie, Michael, Cammer, Allison, Morgan, Debra, Whiting, Susan, de Vos, Maya, Henri-Bhargava, Alexandre, Votova, Kristine, Delmar, Paul, Kerchner, Geoffrey A, Wang, Guoqiao, Bateman, Randall, Klein, Gregory, Andjelkovic, Mirjana, Abi-Saab, Danielle, Bullain, Szofia, Montoya, Alonso, Fontoura, Paulo, Doody, Rachelle, Tai, Elaine, Harvey, David, Hofmann, Carsten, Ristic, Smiljana, Rehal, Sunita, Voyle, Nicola, Baudler, Monika, Verreault, Phylicia, Rousseau, François, Keller, Evelyn, Simard, Alexandra, Azouaou, Nassima, Jarboui, Manel, Talleria, Lorraine, Duguay, Johanne, Mérette, Chantale, Labbé, Annie, de Arco, Rossana Peredo Nunez, Yous, Marie-Lee, Ploeg, Jenny, Kaasalainen, Sharon, Martin, Lori Schindel, Palumbo, Mary Val, Rambur, Betty, McKenna, Lori, Voyer, Philippe, Allaire, Émilie, Li, Bing, Thaut, Michael, Yogaparan, Thirumagal, Shanmuganathan, Thirunathan, Vickneswaran, Anicha, Sriharan, Sruthy, DeMarco, Mari L., Hsiung, Ging-Yuek Robin, Best, John R., Chertkow, Howard, Gauthier, Serge, Karlawish, Jason, Feldman, Howard, Spaner, Caroline, Christie, Brian, Musteata, Stela, Gawryluk, Jodie, Hofer, Scott, Henri-Bhargava, Alex, Kenny, Rebecca, Elliot, Valerie, Kosteniuk, Julie, Chow, Amanda Froehlich, Bayly, Melanie, O’Connell, Megan E., Kortzman, August, O’Connell, Megan, Kirk, Andrew, Conn, David, Sokoloff, Lisa, Feldman, Sid, Chau, James, Moser, Andrea, Lingum, Navena, Gingrich, Shaen, Shaikh, Salma, Rabheru, Kiran, Cassidy, Keri-Leigh, Checkland, Claire, Parsons, Daria, Massie, Ariane S., Mitchell, Julie Spence, Aksenchuk, Sophia, Lindsay, Barbara, Howard, Maria, Shaw, Courtney, Armitage, Gerrard, Capstick, Andrea, McNeil, Heather, Holyoke, Paul, Vines, Chanile, Giosa, Justine, Khan, Bilal, Shultz, Mary, BEAUCHET, Olivier, Sekhon, Harmehr, Allali, Gilles, Montembeault, Maxime, Brodeur, Catherine, Macoir, Joël, Maxwell, Colleen, Maclagan, Laura, Campitelli, Michael, Yao, Shenzhen, Dharma, Christoffer, Sherin, Tracey, Hogan, David, Bronskill, Susan, Ivo, Jessica, Faisal, Sadaf, McDougall, Aidan, Bauer, Jillian, Pritchard, Sarah, Chang, Feng, Mehta, Deval, Syed, Ali, Carter, Caitlin, Sharma, Shaambhavi, Nagge, Jeff, Naglie, Gary, Stasiulis, Elaine, Yamin, Stephanie, Vrkljan, Brenda, Tuokko, Holly, Sanford, Sarah, Porter, Michelle, Polgar, Jan, Myers, Anita, Moorhouse, Paige, Mazer, Barbara, Marshall, Shawn, Gélinas, Isabelle, Crizzle, Alexander, Byszewski, Anna, Belchior, Patricia, Bédard, Michel, Rapoport, Mark, Minish, Duane, Yetman, Linda, Stephenson, Margaret, McCloskey, Rose, Agbaku, Mansa, Jarrett, Pamela, Cavanagh, Jennifer, Loncar, Adele, Demers, Vickie, Gobessi, Linda, Lodha, Vinay, Scerbe, Andrea, Astell, Arlene, DesRoches, Andrea, Panyavin, Ivan, Feltz, Nick, Wittich, Walter, Aubin, Gabrielle, Hogan, Mariah, Swaminathan, Swathi, Altschuler, Aviva, Murphy, Kelly, Guthrie, Dawn, Williams, Nicole, Campos, Jennifer, Mick, Paul, Orange, Joseph B., Pichora-Fuller, M. Kathleen, Savundranayagam, Marie Y., Phillips, Natalie A., Giroud, Nathalie, Pichora-Fuller, Kathy, Al-Yawer, Faisal, Rehan, Sana, Phillips, Natalie, Beauchet, Olivier, Niculescu, Iulia, Iaboni, Andrea, Quirt, Hannah, Penko, Marion, Tsokas, Mario, Marshall, Cecelia, Flint, Alastair, McGilton, Katherine, O’Connell, Megan E, Stewart, Norma J, Seitz, Dallas, Daku, Jean, Hack, Tracy, Hoium, Faye, Kennett-Russill, Deb, Sauter, Kristen, Holley, Joanna, Wimhurst, Christine, Katchaluba, Janet, Mitchell, Debbie, Severina, Elmira, Dallaire-Théroux, Caroline, Saikali, Stéphan, Duchesne, Simon, Sivananthan, Saskia, Mirza, Saira, Saeed, Usman, Knight, Jo, Ramirez, Joel, Stuss, Donald, Yu, Di, Swardfager, Walter, Keith, Julia, Nestor, Sean, Black, Sandra, Masellis, Mario, Joyal, Marilyne, Kotz, Sonja A., Lenglos, Christophe, Renauld, Emmanuelle, Wilson, Maximiliano A., Fecteau, Shirley, Appel, Lora, Kisonas, Erika, Appel, Eva, Bartlett, Deanna, Klein, Jennifer, Rosenberg, Jarred, Smith, Christopher, Ali, Suad, Narang, Tanya, Wiseman, Micaela, Ein, Natalie, Orchanian-Cheff, Ani, Rylett, Jane, Hogan, David B., Rockwood, Kenneth, Dixon, Roger, Sun, Winnie, Hawkins, Stacey A., Awde, Carolee, Kay, Kelly, Huntsbarger, Deana, Ferrier, Erin, Sourial, Nadia, Arsenault-Lapierre, Genevieve, McAiney, Carrie, Vedel, Isabelle, Ingram, K. Jennifer, Frank, Andrew, Sabra, Iman, Wallace, Bruce, Breau, Michael, Sweet, Lisa, Goubran, Rafiq, Knoefel, Frank, Goubran, Rafik, Stroulia, Eleni, Ault, Laura, Kecskemet, Judith, Guseva, Elena, Lungu, Ovidiu, Goldman, Sondra, Wilchesky, Machelle, Johri, Fozia, Turner, Angelese, Lavoie, Monica, Tang-Wai, David, Leonard, Carol, Graham, Naida L., Rochon, Elizabeth, Middleton, Laura, Herrmann, Nathan, Oh, Paul, Regan, Kayla, Bechard, Lauren, Lanctôt, Krista, Freeman, Shannon, Pettersen, Jacqueline, Tomasone, Jennifer, Dupuis, Sherry, Giangregorio, Lora, Ferris, Rebecca, Stultz, Tim, Mallard, Kirsten, Campbell, Elaine, Chatterjee, Atri, Mackenzie, Ian, Reinshagen, Veronica Hirsh, Ducharme, Blake, Mousavi, Ali, Gill, Sascha, Mouches, Pauline, Wang, Meng, Rajasheskar, Deepthi, MacMaster, Frank, Forkert, Nils, Smith, Eric, Ismail, Zahinoor, Varatharajah, Breni, Camicioli, Richard, Gee, Myrlene, Zwiers, Angela, Sekhon, Ramnik, Charlton, Anna, Arsenault-Lapierre, Geneviève, Ingram, Jennifer, Hawkins, Stacey, Mousavi, SeyedAli, Mackenzie, Ian R. A., Hirsh-Reinshagen, Veronica, Hsiung, Ging-Yuek. R., Gillingham, Susan M.E., Anderson, Nicole D., Alain, Claude, Georgievski, Georgi, Alfaro, Leonardo, McClenaghan, Meridith, Soares, Daniela, Matheson, Maureen, Stanoulis, Krisanne, Boyle, Daniel, Chau, Linh, Pelc, Jordan, Snash, Nadia, Byrne, Joanne, Elalouf, Karine, Alfaro, Andrea Urqueta, Johnson, Aaron, Marinier, Julie-Andrée, Kehayia, Eva, Gagné, Jean-Pierre, Murphy, Caitlin, Ellen, Ruth, Flowers, Brandi, Boulton, Karen Lee, Subotic, Arsenije, McCreary, Cheryl R., Nguyen, Amanda, Saad, Feryal, Alvarez, Ana, Beaudin, Andrew E, Pike, Bruce, Smith, Eric E, Hu, Sophie, Patten, Scott, Fick, Gordon, Sapkota, Shraddha, Mirza, Saira Saeed, Scott, Christopher J., Stuss, Donald T., Black, Sandra E., Le Blanc, Gabriella, Ducharme, Simon, Meilleur-Durand, Synthia, Lévesque, Marianne, St-Onge, Frédéric, Cunnane, Stephen, Villeneuve, Sylvia, Callahan, Brandy, Laforce, Robert, Cetin-Sahin, Deniz, Cummings, Greta G., Schuster, Tibor, Karanofsky, Mark, De Jesus, Belmir J., Cassani, Raymundo, Cecchi, Marco, Fadem, K. C., McGeown, William J., Falk, Tiago H., Chu, Charlene, Zdaniuk, Natalia, Wang, Rosalie, Ouellet, Marie-Christine, Cassivi-Joncas, Alison, Godard-Sebillotte, Claire, Rochette, Louis, Pelletier, Eric, Strumpf, Erin, Margo-Dermer, Eva, Silver, Hilah, Vafaei, Rod, Fok, Alice C, Hsiung, Ging-Yuek R., Ursenbach, Jake, Bethell, Jennifer, Neuman, Mark D, Bateman, Brian T, Hill, Andrea, Wunsch, Hannah, Ritchie, Kim, Cramm, Heidi, Aiken, Alice, Donnelly, Catherine, Goldie, Katie, Delara, Mahin, Ozzoude, Miracle, Varriano, Brenda, McLaughlin, Paula, Troyer, Angela, Bartha, Robert, Symons, Sean, Kwan, Donna, Tan, Brian, Swartz, Richard H., Saposnik, Gustavo, Tartaglia, Maria C., Ahuja, Manan, Siddhpuria, Shailee, Gormley, Jessica, Reppas, Christina, Wong, Eric, Lee, Justin, Patterson, Christopher, Walker, Jennifer, Warry, Wayne, Blind, Melissa, Allaby, Cheryl, Pitawanakwat, Karen, Zhao, Yantao, Lemieux, Andrine, Jacklin, Kristen, Crowshoe, Lindsay, Boehme, Gail, McKenna, Betty, Boyling, Elaine, Webkamigad, Sharlene, Bigeagle, Louise, Akan, Nicole, Wallace, Lindsay, Theou, Olga, Bennett, David, Darvesh, Sultan, Kirkland, Susan, Fisk, John, Andrew, Melissa, Cullen, Stephanie, Carroll, Susan, Mahon, Joel, Sarquis-Adamson, Yanina, Montero-Odasso, Manuel, Sharma, Nabina, Beaton, Derek, Roberts, Angela, Munoz, Doug, Swartz, Richard, Breen, David, Lang, Anthony, Fischer, COrrine, Fischer, Corrine, Kumar, Sanjeeve, Freedman, Morris, Finger, Elizabeth, Zinman, Lorne, Grimes, David A., Sunderland, Kelly M., Binns, Malcolm A., Strother, Stephen C., Mandzia, Jennifer, Orange, JB, Tartaglia, Carmela, El Shatshat, Amna, Rao, Praveen P.N., Teves, Julia, Bodkin, R Jack, Ho, Joanne M-W, Mehdizadeh, Sina, Dolatabadi, Elham, Ng, Kimberley-Dale, Arora, Twinkle, Jizmejian, Melody, Mansfield, Avril, Taati, Babak, Levy, Jake, Savard, Melissa, Pascoal, Tharick, Soucy, Jean-Paul, Rosa-Neto, Pedro, Martins, Felicia, Waller, Shannon, Flora, Parminder, Morland, Chris, Donovan, Steve, Fels, Deborah, Desai, Shital, Boger, Jennifer, Shashtri, Karan, Persaud, Deanna, Marashi, Sheida, Nedlund, Ann-Charlotte, Mäki-Petäjä-Leinonen, Anna, Nygård, Louise, Issakainen, Mervi, ryd, Charlotta, Pan, Yuhan, Joddrell, Phil, Dove, Erica, Owens, Hollis, Park, Elly, Liu, Lili, Kaufman, David, Simonian, Natalie, Chen, Ying, Sunderland, Kelly, Fraser, Julia, Swartz, Rick, Strother, Stephen, Legrand, Diego, Roberge, Pasquale, Vanasse, Alain, Bocti, Christian, Pirrie, Lorraine, Gray, Carolyn Steele, Nippak, Pria, Coughlan, Dave, Teselink, Johannes, Hermann, Nathan, Rasquinha, Fawn, Lanctot, Krista, Webber, Jodi, Woo, Kevin, Chamoun, Elicia, Coulombe, Valérie, Sellami, Leila, Paquette-Raynard, Emmanuelle, Gardner, Sandra, van Zon, Lorraine, Moy, Sally, Sidrak, Mariam, Sternhill, Janis, Feldman, Sidney, Karuza, Jurgis, Berall, Anna, Thomas, Neil, Mattek, Nora, Riley, Thomas, Reynolds, Christina, Marcoe, Jennifer, Sharma, Nicole, Kaye, Jeffrey, Jagtap, Shreya, Rotenberg, Shlomit, Vandermorris, Susan, Anderson, ND, Dawson, DR, Chater, Catherine, Soor, Jaspreet, Ji, Xiang, Koo, Morgan, Compagnone, Jordana, Kertes, Peter, Juby, Angela, Mager, Diana, Davis, Christopher, Jay, David, Blackburn, Toni, Brocks, Dion, Lee, Hyunwoo, Wiggermann, Vanessa, Rauscher, Alexander, Lam, Kevin, Tam, Roger, Popuri, Karteek, Beg, Mirza Faisal, Jacova, Claudia, Sossi, Vesna, Bindra, Jessica, Bouvier, Liziane, Monetta, Laura, Vitali, Paolo, Martel-Sauvageau, Vincent, Godin, Judith, McNeil, Shelly, McElhaney, Janet, Laughton, Thomas, Ho, Joanne, Tung, Jennifer, Dubé, Joseph B., Lin, Tianzhen, Best, Sarah, Truemner, Julia, Sargeant, Patricia L., Borrie, Michael J., Fogarty, Jennifer, Bassi, Nimi, Di Prospero, Cynthia, Whitehead, Victor, Pilon, Randi, Wong, Timothy, Elhayek, Nada, Dasgupta, Monidipa, Davis, Daniel, ORegan, Niamh, Kröger, Edeltraut, Furrer, Daniela, Wilcheski, Machelle, Morin, Michèle, Carmichael, Pierre-Hugues, Champoux, Nathalie, Monette, Johanne, Giguère, Anik, Aubin, Michèle, Durand, Pierre, Whiteside, Jena, Mele, Bria, Merrikh, Daria, Goodarzi, Zahra, Seary, Judith Anne, Bulley, Heather, Diciacca, Allison, Esseltine, Julia, Gaiger, Erin, Jankovic, Ivana, Mackenzie, Stephanie, McBride, Meghan, Knopp-Sihota, Jennifer A., Hoben, Mathias, Poss, Jeffrey W., Rachor, Geoffrey S., Estabrooks, Carole A., and Iroanyah, Ngozi

Subjects
Abstracts: Posters
Published
2020

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