252 results on '"Rybak K"'
Search Results
2. Curriculum Kardiologie: 2., aktualisierte Auflage
- Author
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Werdan, K., Baldus, St., Bauersachs, J., Baumgartner, H., Bongarth, C. M., Buerke, M., Dörr, R., Duncker, D., Eckardt, L., El-Armouche, A., Elsässer, A., Fach, A., Flachskampf, F. A., Gabelmann, M., Griebenow, R., Heinemann-Meerz, S., Hoffmeister, H. M., Katus, H. A., Kaul, N., Krämer, L.-I., Kuhn, B., Lange, T., Lehmann, L. H., Lugenbiel, P., Michels, G., Müller-Werdan, U., Oldenburg, O., Rittger, H., Rottbauer, W., Rybak, K., Sack, S., Skobel, C. E., Smetak, N., Thiele, H., Tiefenbacher, C., Tiemann, K., Voelker, W., Zeiher, A., and Frey, N.
- Published
- 2020
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3. Grundlegende Strukturmerkmale eines kardiologischen Telemedizinzentrums für Patienten mit Herzinsuffizienz und implantierten Devices, Herzrhythmusstörungen und erhöhtem Risiko für den plötzlichen Herztod: Empfehlungen der Arbeitsgruppe 33 Telemonitoring in der Deutschen Gesellschaft für Kardiologie, Herz- und Kreislaufforschung e. V.
- Author
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Helms, T. M., Stockburger, M., Köhler, F., Leonhardt, V., Müller, A., Rybak, K., Sack, S., Schwab, J. O., Störk, S., Zippel-Schultz, B., and Perings, C. A.
- Published
- 2019
- Full Text
- View/download PDF
4. Adaptive Evolution of Escherichia coli K-12 MG1655 Grown on Ethanol and Glycerol
- Author
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Eremina, N. S., Slivinskaya, E. A., Yampolskaya, T. A., Rybak, K. V., Altman, I. B., Ptitsyn, L. R., and Stoynova, N. V.
- Published
- 2018
- Full Text
- View/download PDF
5. Nutzenbewertung des strukturierten Telemonitorings mithilfe von aktiven Herzrhythmusimplantaten
- Author
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Stockburger, M., Helms, T. M., Perings, C. A., Deneke, T., Köhler, F., Leonhardt, V., Müller, A., Piorkowski, C., Rybak, K., and Sack, S.
- Published
- 2017
- Full Text
- View/download PDF
6. Das Telemedizinische Zentrum als essenzieller Baustein konzeptioneller Ansätze zum Telemonitoring kardialer Patienten: Anforderungen an Leistungen, Qualität und technische Umsetzung von Telemonitoring
- Author
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Helms, T. M., Müller, A., Perings, C., Köhler, F., Leonhardt, V., Rybak, K., Sack, S., and Stockburger, M.
- Published
- 2017
- Full Text
- View/download PDF
7. Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice:: GLORIA-AF Registry
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Lip G. Y. H., Kotalczyk A., Teutsch C., Diener H. -C., Dubner S. J., Halperin J. L., Ma C. -S., Rothman K. J., Marler S., Gurusamy V. K., Huisman M. V., Abban D. W., Aziz E., Kalan M. B., Abdul N., Backes L. M., Bradman D., Abud A. M., Badings E., Brautigam D., Adams F., Bagni E., Breton N., Addala S., Baker S. H., Brouwers P. J. A. M., Adragao P., Bala R., Browne K., Ageno W., Baldi A., Cortada J. B., Aggarwal R., Bando S., Bruni A., Agosti S., Banerjee S., Brunschwig C., Agostoni P., Bank A., Buathier H., Aguilar F., Esquivias G. B., Buhl A., Linares J. A., Barr C., Bullinga J., Aguinaga L., Bartlett M., Cabrera J. W., Ahmed J., Basic Kes V., Caccavo A., Aiello A., Baula G., Cai S., Ainsworth P., Behrens S., Caine S., Aiub J. R., Bell A., Calo L., Al-Dallow R., Benedetti R., Calvi V., Alderson L., Mazuecos J. B., Sanchez M. C., Velasco J. A. A., Benhalima B., Candeias R., Alexopoulos D., Bergler-Klein J., Capuano V., Manterola F. A., Berneau J. -B., Capucci A., Aliyar P., Bernstein R. A., Caputo R., Alonso D., Berrospi P., Rizo T. C., da Costa F. A. A., Berti S., Cardona F., Amado J., Berz A., da Costa Darrieux F. C., Amara W., Best E., Vera Y. C. D., Amelot M., Bettencourt P., Carolei A., Amjadi N., Betzu R., Carreno S., Ammirati F., Bhagwat R., Carvalho P., Andrade M., Bhatta L., Cary S., Andrawis N., Biscione F., Casu G., Annoni G., Bisignani G., Cavallini C., Ansalone G., Black T., Cayla G., Ariani M. K., Bloch M. J., Celentano A., Arias J. C., Bloom S., Cha T. -J., Armero S., Blumberg E., Cha K. S., Arora C., Bo M., Chae J. K., Aslam M. S., Bohmer E., Chalamidas K., Asselman M., Bollmann A., Challappa K., Audouin P., Bongiorni M. G., Chand S. P., Augenbraun C., Boriani G., Chandrashekar H., Aydin S., Boswijk D. J., Chartier L., Bott J., Chatterjee K., Ayryanova I., Bottacchi E., Ayala C. A. C., Cheema A., Davis G., Evonich R., Davy J. -M., Evseeva O., Chen L., Dayer M., Ezhov A., Chen S. -A., De Biasio M., Fahmy R., Chen J. H., De Bonis S., Fang Q., Chiang F. -T., De Caterina R., Farsad R., Chiarella F., De Franceschi T., Fauchier L., Chih-Chan L., de Groot J. R., Favale S., Cho Y. K., De Horta J., Fayard M., Choi J. -I., De La Briolle A., Fedele J. L., Choi D. J., de la Pena Topete G., Fedele F., Chouinard G., de Paola A. A. V., Fedorishina O., Chow D. H. -F., de Souza W., Fera S. R., Chrysos D., de Veer A., Ferreira L. G. G., Chumakova G., De Wolf L., Ferreira J., Valenzuela E. J. J. R. C., Decoulx E., Ferri C., Nica N. C., Deepak S., Ferrier A., Cislowski D. J., Defaye P., Ferro H., Clay A., Munoz F. D. -C., Finsen A., Clifford P., Brkljacic D. D., First B., Cohen A., Deumite N. J., Fischer S., Cohen M., Di Legge S., Fonseca C., Cohen S., Diemberger I., Almeida L. F., Colivicchi F., Dietz D., Forman S., Collins R., Dionisio P., Frandsen B., Colonna P., Dong Q., French W., Compton S., dos Santos F. R., Friedman K., Connolly D., Dotcheva E., Friese A., Conti A., Doukky R., Fruntelata A. G., Buenostro G. C., D'Souza A., Fujii S., Coodley G., Dubrey S., Fumagalli S., Cooper M., Ducrocq X., Fundamenski M., Coronel J., Dupljakov D., Furukawa Y., Corso G., Duque M., Gabelmann M., Sales J. C., Dutta D., Gabra N., Cottin Y., Duvilla N., Gadsboll N., Covalesky J., Duygun A., Galinier M., Cracan A., Dziewas R., Gammelgaard A., Crea F., Eaton C. B., Ganeshkumar P., Crean P., Eaves W., Gans C., Crenshaw J., Ebels-Tuinbeek L. A., Quintana A. G., Cullen T., Ehrlich C., Gartenlaub O., Darius H., Eichinger-Hasenauer S., Gaspardone A., Dary P., Eisenberg S. J., Genz C., Dascotte O., Jabali A. E., Georger F., Dauber I., Shahawy M. E., Georges J. -L., Davalos V., Hernandes M. E., Georgeson S., Davies R., Izal A. E., Giedrimas E., Gierba M., Haruna T., Jarmukli N., Ortega I. G., Hayek E., Jeanfreau R. J., Gillespie E., Healey J., Jenkins R. D., Giniger A., Hearne S., Sanchez C. J., Giudici M. C., Heffernan M., Jimenez J., Gkotsis A., Heggelund G., Jobe R., Glotzer T. V., Heijmeriks J. A., Joen-Jakobsen T., Gmehling J., Hemels M., Jones N., Gniot J., Hendriks I., Jorge J. C. M., Goethals P., Henein S., Jouve B., Goldbarg S., Her S. -H., Jung B. C., Goldberg R., Hermany P., Jung K. T., Goldmann B., Del Rio J. E. H., Jung W., Golitsyn S., Higashino Y., Kachkovskiy M., Gomez S., Hill M., Kafkala K., Mesa J. G., Hisadome T., Kalinina L., Gonzalez V. B., Hishida E., Kallmunzer B., Hermosillo J. A. G., Hoffer E., Kamali F., Lopez V. M. G., Hoghton M., Kamo T., Gorka H., Hong K., Kampus P., Gornick C., Hong S., Kashou H., Gorog D., Horbach S., Kastrup A., Gottipaty V., Horiuchi M., Katsivas A., Goube P., Hou Y., Kaufman E., Goudevenos I., Hsing J., Kawai K., Graham B., Huang C. -H., Kawajiri K., Greer G. S., Huckins D., Kazmierski J. F., Gremmler U., Hughes K., Keeling P., Grena P. G., Huizinga A., Saraiva J. F. K., Grond M., Hulsman E. L., Ketova G., Gronda E., Hung K. -C., Khaira A. S., Gronefeld G., Hwang G. -S., Khripun A., Gu X., Ikpoh M., Kim D. -I., Torres I. G. T., Imberti D., Kim Y. H., Guardigli G., Ince H., Kim N. H., Guevara C., Indolfi C., Kim D. K., Guignier A., Inoue S., Kim J. S., Gulizia M., Irles D., Gumbley M., Iseki H., Kim K. S., Gunther A., Israel C. N., Kim J., Ha A., Iteld B., Kinova E., Hahalis G., Iyer V., Klein A., Hakas J., Jackson-Voyzey E., Kmetzo J. J., Hall C., Jaffrani N., Kneller G. L., Han B., Jager F., Knezevic A., Han S., James M., Koh S. M. A., Hargrove J., Jang S. -W., Koide S., Hargroves D., Jaramillo N., Kollias A., Kooistra J. A., Li W., McClure J., Koons J., Li X., McCormack T., Koschutnik M., Lichy C., McGarity W., Kostis W. J., Lieber I., McIntyre H., Kovacic D., Rodriguez R. H. L., McLaurin B., Kowalczyk J., Lin H., Alvaro F., Palomino M., Koziolova N., Melandri F., Kraft P., Liu F., Meno H., Kragten J. A., Liu H., Menzies D., Krantz M., Esperon G. L., Mercader M., Krause L., Navarro N. L., Meyer C., Krenning B. J., Lo E., Meyer B. J., Krikke F., Lokshyn S., Miarka J., Kromhout Z., Lopez A., Mibach F., Krysiak W., Lopez-Sendon J. L., Michalski D., Kumar P., Filho A. M. L., Michel P., Kumler T., Lorraine R. S., Chreih R. M., Kuniss M., Luengas C. A., Luengas A., Mikdadi G., Kuo J. -Y., Luke R., Mikus M., Kuppers A., Luo M., Milicic D., Kurrelmeyer K., Lupovitch S., Militaru C., Kwak C. H., Lyrer P., Minaie S., Laboulle B., Ma C., Minescu B., Labovitz A., Ma G., Mintale I., Ter Lai W., Madariaga I., Mirault T., Lam A., Maeno K., Mirro M. J., Lam Y. Y., Magnin D., Mistry D., Lanas Zanetti F., Maid G., Miu N. V., Landau C., Mainigi S. K., Miyamoto N., Landini G., Makaritsis K., Moccetti T., Lanna Figueiredo E., Malhotra R., Mohammed A., Larsen T., Manning R., Nor A. M., Lavandier K., Manolis A., Mollerus M., LeBlanc J., Hurtado H. A. M., Molon G., Lee M. H., Mantas I., Mondillo S., Lee C. -H., Jattin F. M., Moniz P., Lehman J., Maqueda V., Mont L., Leitao A., Marchionni N., Montagud V., Lellouche N., Ortuno F. M., Montana O., Lelonek M., Santana A. M., Monti C., Lenarczyk R., Martinez J., Moretti L., Lenderink T., Maskova P., Mori K., Gonzalez S. L., Hernandez N. M., Moriarty A., Leong-Sit P., Matsuda K., Morka J., Leschke M., Maurer T., Moschini L., Ley N., Mauro C., Moschos N., Li Z., May E., Mugge A., Mayer N., Mulhearn T. J., Muresan C., Jose E. P., Precoma D. B., Muriago M., Padilla F. G. P., Prelle A., Musial W., Rios V. P., Prodafikas J., Musser C. W., Pajes G., Protasov K., Musumeci F., Pandey A. S., Pye M., Nageh T., Paparella G., Qiu Z., Nakagawa H., Paris F., Quedillac J. -M., Nakamura Y., Park H. W., Raev D., Nakayama T., Park J. S., Grado C. A. R., Nam G. -B., Parthenakis F., Rahimi S., Nanna M., Passamonti E., Raisaro A., Natarajan I., Patel R. J., Rama B., Nayak H. M., Patel J., Ramos R., Naydenov S., Patel M., Ranieri M., Nazlic J., Patrick J., Raposo N., Nechita A. C., Jimenez R. P., Rashba E., Nechvatal L., Paz A., Rauch-Kroehnert U., Negron S. A., Pengo V., Reddy R., Neiman J., Pentz W., Renda G., Neuenschwander F. C., Perez B., Reza S., Neves D., Rios A. M. P., Ria L., Neykova A., Perez-Cabezas A., Richter D., Miguel R. N., Perlman R., Rickli H., Nijmeh G., Persic V., Rieker W., Nizov A., Perticone F., Vera T. R., Campos R. N., Peters T. K., Ritt L. E., Nossan J., Petkar S., Roberts D., Novikova T., Pezo L. F., Briones I. R., Nowalany-Kozielska E., Pflucke C., Escudero A. E. R., Nsah E., Pham D. N., Pascual C. R., Fragoso J. C. N., Phillips R. T., Roman M., Nurgalieva S., Phlaum S., Romeo F., Nuyens D., Pieters D., Ronner E., Nyvad O., Pineau J., Roux J. -F., de Los Rios Ibarra M. O., Pinter A., Rozkova N., O'Donnell P., Pinto F., Rubacek M., O'Donnell M., Pisters R., Rubalcava F., Oh S., Pivac N., Russo A. M., Oh Y. S., Pocanic D., Rutgers M. P., Oh D., Podoleanu C., Rybak K., O'Hara G., Politano A., Said S., Oikonomou K., Poljakovic Z., Sakamoto T., Olivares C., Pollock S., Salacata A., Oliver R., Garcea J. P., Salem A., Ruiz R. O., Poppert H., Bodes R. S., Olympios C., Porcu M., Saltzman M. A., Omaszuk-Kazberuk A., Reino A. P., Salvioni A., Asensi J. O., Prasad N., Vallejo G. S., Fernandez M. S., Sokal A., Tu T. M., Saporito W. F., Yan Y. S. O., Tuininga Y., Sarikonda K., Sotolongo R., Turakhia M., Sasaoka T., de Souza O. F., Turk S., Sati H., Sparby J. A., Turner W., Savelieva I., Spinar J., Tveit A., Scala P. -J., Sprigings D., Tytus R., Schellinger P., Spyropoulos A. C., Valadao C., Scherr C., Stakos D., van Bergen P. F. M. M., Schmitz L., Steinwender C., van de Borne P., Schmitz K. -H., Stergiou G., van den Berg B. J., Schmitz B., Stiell I., van der Zwaan C., Schnabel T., Stoddard M., Van Eck M., Schnupp S., Stoikov A., Vanacker P., Schoeniger P., Streb W., Vasilev D., Schon N., Styliadis I., Vasilikos V., Schwimmbeck P., Su G., Vasilyev M., Seamark C., Su X., Veerareddy S., Searles G., Sudnik W., Mino M. V., Seidl K. -H., Sukles K., Venkataraman A., Seidman B., Sun X., Verdecchia P., Sek J., Swart H., Versaci F., Sekaran L., Szavits-Nossan J., Vester E. G., Serrati C., Taggeselle J., Vial H., Shah N., Takagi Y., Victory J., Shah V., Takhar A. P. S., Villamil A., Shah A., Tamm A., Vincent M., Shah S., Tanaka K., Vlastaris A., Sharma V. K., Tanawuttiwat T., Dahl J., Shaw L., Tang S., Vora K., Sheikh K. H., Tang A., Vranian R. B., Shimizu N., Tarsi G., Wakefield P., Shimomura H., Tassinari T., Wang N., Shin D. -G., Tayal A., Wang M., Shin E. -S., Tayebjee M., Wang X., Shite J., Berg J. M., Wang F., Sibilio G., Tesloianu D., Wang T., Silver F., The S. H. K., Warner A. L., Sime I., Thomas D., Watanabe K., Simmers T. A., Timsit S., Wei J., Singh N., Tobaru T., Weimar C., Siostrzonek P., Tomasik A. R., Weiner S., Smadja D., Torosoff M., Weinrich R., Smith D. W., Touze E., Wen M. -S., Snitman M., Trendafilova E., Wiemer M., Filho D. S., Tsai W. K., Wiggers P., Soda H., Tse H. F., Wilke A., Sofley C., Tsutsui H., Williams D., Williams M. L., Yan P. Y. B., Zhang P., Witzenbichler B., Yang T., Zhang J., Wong B., Yao J., Zhao S. P., Wong K. S. L., Yeh K. -H., Zhao Y., Wozakowska-Kaplon B., Yin W. H., Zhao Z., Wu S., Yotov Y., Zheng Y., Wu R. C., Zahn R., Zhou J., Wunderlich S., Zarich S., Zimmermann S., Wyatt N., Zenin S., Zini A., Wylie J., Zeuthen E. L., Zizzo S., Xu Y., Zhang H., Zong W., Xu X., Zhang D., Zukerman L. S., Yamanoue H., Zhang X., Yamashita T., Cardiology, ACS - Heart failure & arrhythmias, Lip G.Y.H., Kotalczyk A., Teutsch C., Diener H.-C., Dubner S.J., Halperin J.L., Ma C.-S., Rothman K.J., Marler S., Gurusamy V.K., Huisman M.V., Abban D.W., Aziz E., Kalan M.B., Abdul N., Backes L.M., Bradman D., Abud A.M., Badings E., Brautigam D., Adams F., Bagni E., Breton N., Addala S., Baker S.H., Brouwers P.J.A.M., Adragao P., Bala R., Browne K., Ageno W., Baldi A., Cortada J.B., Aggarwal R., Bando S., Bruni A., Agosti S., Banerjee S., Brunschwig C., Agostoni P., Bank A., Buathier H., Aguilar F., Esquivias G.B., Buhl A., Linares J.A., Barr C., Bullinga J., Aguinaga L., Bartlett M., Cabrera J.W., Ahmed J., Basic Kes V., Caccavo A., Aiello A., Baula G., Cai S., Ainsworth P., Behrens S., Caine S., Aiub J.R., Bell A., Calo L., Al-Dallow R., Benedetti R., Calvi V., Alderson L., Mazuecos J.B., Sanchez M.C., Velasco J.A.A., Benhalima B., Candeias R., Alexopoulos D., Bergler-Klein J., Capuano V., Manterola F.A., Berneau J.-B., Capucci A., Aliyar P., Bernstein R.A., Caputo R., Alonso D., Berrospi P., Rizo T.C., da Costa F.A.A., Berti S., Cardona F., Amado J., Berz A., da Costa Darrieux F.C., Amara W., Best E., Vera Y.C.D., Amelot M., Bettencourt P., Carolei A., Amjadi N., Betzu R., Carreno S., Ammirati F., Bhagwat R., Carvalho P., Andrade M., Bhatta L., Cary S., Andrawis N., Biscione F., Casu G., Annoni G., Bisignani G., Cavallini C., Ansalone G., Black T., Cayla G., Ariani M.K., Bloch M.J., Celentano A., Arias J.C., Bloom S., Cha T.-J., Armero S., Blumberg E., Cha K.S., Arora C., Bo M., Chae J.K., Aslam M.S., Bohmer E., Chalamidas K., Asselman M., Bollmann A., Challappa K., Audouin P., Bongiorni M.G., Chand S.P., Augenbraun C., Boriani G., Chandrashekar H., Aydin S., Boswijk D.J., Chartier L., Bott J., Chatterjee K., Ayryanova I., Bottacchi E., Ayala C.A.C., Cheema A., Davis G., Evonich R., Davy J.-M., Evseeva O., Chen L., Dayer M., Ezhov A., Chen S.-A., De Biasio M., Fahmy R., Chen J.H., De Bonis S., Fang Q., Chiang F.-T., De Caterina R., Farsad R., Chiarella F., De Franceschi T., Fauchier L., Chih-Chan L., de Groot J.R., Favale S., Cho Y.K., De Horta J., Fayard M., Choi J.-I., De La Briolle A., Fedele J.L., Choi D.J., de la Pena Topete G., Fedele F., Chouinard G., de Paola A.A.V., Fedorishina O., Chow D.H.-F., de Souza W., Fera S.R., Chrysos D., de Veer A., Ferreira L.G.G., Chumakova G., De Wolf L., Ferreira J., Valenzuela E.J.J.R.C., Decoulx E., Ferri C., Nica N.C., Deepak S., Ferrier A., Cislowski D.J., Defaye P., Ferro H., Clay A., Munoz F.D.-C., Finsen A., Clifford P., Brkljacic D.D., First B., Cohen A., Deumite N.J., Fischer S., Cohen M., Di Legge S., Fonseca C., Cohen S., Diemberger I., Almeida L.F., Colivicchi F., Dietz D., Forman S., Collins R., Dionisio P., Frandsen B., Colonna P., Dong Q., French W., Compton S., dos Santos F.R., Friedman K., Connolly D., Dotcheva E., Friese A., Conti A., Doukky R., Fruntelata A.G., Buenostro G.C., D'Souza A., Fujii S., Coodley G., Dubrey S., Fumagalli S., Cooper M., Ducrocq X., Fundamenski M., Coronel J., Dupljakov D., Furukawa Y., Corso G., Duque M., Gabelmann M., Sales J.C., Dutta D., Gabra N., Cottin Y., Duvilla N., Gadsboll N., Covalesky J., Duygun A., Galinier M., Cracan A., Dziewas R., Gammelgaard A., Crea F., Eaton C.B., Ganeshkumar P., Crean P., Eaves W., Gans C., Crenshaw J., Ebels-Tuinbeek L.A., Quintana A.G., Cullen T., Ehrlich C., Gartenlaub O., Darius H., Eichinger-Hasenauer S., Gaspardone A., Dary P., Eisenberg S.J., Genz C., Dascotte O., Jabali A.E., Georger F., Dauber I., Shahawy M.E., Georges J.-L., Davalos V., Hernandes M.E., Georgeson S., Davies R., Izal A.E., Giedrimas E., Gierba M., Haruna T., Jarmukli N., Ortega I.G., Hayek E., Jeanfreau R.J., Gillespie E., Healey J., Jenkins R.D., Giniger A., Hearne S., Sanchez C.J., Giudici M.C., Heffernan M., Jimenez J., Gkotsis A., Heggelund G., Jobe R., Glotzer T.V., Heijmeriks J.A., Joen-Jakobsen T., Gmehling J., Hemels M., Jones N., Gniot J., Hendriks I., Jorge J.C.M., Goethals P., Henein S., Jouve B., Goldbarg S., Her S.-H., Jung B.C., Goldberg R., Hermany P., Jung K.T., Goldmann B., Del Rio J.E.H., Jung W., Golitsyn S., Higashino Y., Kachkovskiy M., Gomez S., Hill M., Kafkala K., Mesa J.G., Hisadome T., Kalinina L., Gonzalez V.B., Hishida E., Kallmunzer B., Hermosillo J.A.G., Hoffer E., Kamali F., Lopez V.M.G., Hoghton M., Kamo T., Gorka H., Hong K., Kampus P., Gornick C., Hong S., Kashou H., Gorog D., Horbach S., Kastrup A., Gottipaty V., Horiuchi M., Katsivas A., Goube P., Hou Y., Kaufman E., Goudevenos I., Hsing J., Kawai K., Graham B., Huang C.-H., Kawajiri K., Greer G.S., Huckins D., Kazmierski J.F., Gremmler U., Hughes K., Keeling P., Grena P.G., Huizinga A., Saraiva J.F.K., Grond M., Hulsman E.L., Ketova G., Gronda E., Hung K.-C., Khaira A.S., Gronefeld G., Hwang G.-S., Khripun A., Gu X., Ikpoh M., Kim D.-I., Torres I.G.T., Imberti D., Kim Y.H., Guardigli G., Ince H., Kim N.H., Guevara C., Indolfi C., Kim D.K., Guignier A., Inoue S., Kim J.S., Gulizia M., Irles D., Gumbley M., Iseki H., Kim K.S., Gunther A., Israel C.N., Kim J., Ha A., Iteld B., Kinova E., Hahalis G., Iyer V., Klein A., Hakas J., Jackson-Voyzey E., Kmetzo J.J., Hall C., Jaffrani N., Kneller G.L., Han B., Jager F., Knezevic A., Han S., James M., Koh S.M.A., Hargrove J., Jang S.-W., Koide S., Hargroves D., Jaramillo N., Kollias A., Kooistra J.A., Li W., McClure J., Koons J., Li X., McCormack T., Koschutnik M., Lichy C., McGarity W., Kostis W.J., Lieber I., McIntyre H., Kovacic D., Rodriguez R.H.L., McLaurin B., Kowalczyk J., Lin H., Alvaro F., Palomino M., Koziolova N., Melandri F., Kraft P., Liu F., Meno H., Kragten J.A., Liu H., Menzies D., Krantz M., Esperon G.L., Mercader M., Krause L., Navarro N.L., Meyer C., Krenning B.J., Lo E., Meyer B.J., Krikke F., Lokshyn S., Miarka J., Kromhout Z., Lopez A., Mibach F., Krysiak W., Lopez-Sendon J.L., Michalski D., Kumar P., Filho A.M.L., Michel P., Kumler T., Lorraine R.S., Chreih R.M., Kuniss M., Luengas C.A., Luengas A., Mikdadi G., Kuo J.-Y., Luke R., Mikus M., Kuppers A., Luo M., Milicic D., Kurrelmeyer K., Lupovitch S., Militaru C., Kwak C.H., Lyrer P., Minaie S., Laboulle B., Ma C., Minescu B., Labovitz A., Ma G., Mintale I., Ter Lai W., Madariaga I., Mirault T., Lam A., Maeno K., Mirro M.J., Lam Y.Y., Magnin D., Mistry D., Lanas Zanetti F., Maid G., Miu N.V., Landau C., Mainigi S.K., Miyamoto N., Landini G., Makaritsis K., Moccetti T., Lanna Figueiredo E., Malhotra R., Mohammed A., Larsen T., Manning R., Nor A.M., Lavandier K., Manolis A., Mollerus M., LeBlanc J., Hurtado H.A.M., Molon G., Lee M.H., Mantas I., Mondillo S., Lee C.-H., Jattin F.M., Moniz P., Lehman J., Maqueda V., Mont L., Leitao A., Marchionni N., Montagud V., Lellouche N., Ortuno F.M., Montana O., Lelonek M., Santana A.M., Monti C., Lenarczyk R., Martinez J., Moretti L., Lenderink T., Maskova P., Mori K., Gonzalez S.L., Hernandez N.M., Moriarty A., Leong-Sit P., Matsuda K., Morka J., Leschke M., Maurer T., Moschini L., Ley N., Mauro C., Moschos N., Li Z., May E., Mugge A., Mayer N., Mulhearn T.J., Muresan C., Jose E.P., Precoma D.B., Muriago M., Padilla F.G.P., Prelle A., Musial W., Rios V.P., Prodafikas J., Musser C.W., Pajes G., Protasov K., Musumeci F., Pandey A.S., Pye M., Nageh T., Paparella G., Qiu Z., Nakagawa H., Paris F., Quedillac J.-M., Nakamura Y., Park H.W., Raev D., Nakayama T., Park J.S., Grado C.A.R., Nam G.-B., Parthenakis F., Rahimi S., Nanna M., Passamonti E., Raisaro A., Natarajan I., Patel R.J., Rama B., Nayak H.M., Patel J., Ramos R., Naydenov S., Patel M., Ranieri M., Nazlic J., Patrick J., Raposo N., Nechita A.C., Jimenez R.P., Rashba E., Nechvatal L., Paz A., Rauch-Kroehnert U., Negron S.A., Pengo V., Reddy R., Neiman J., Pentz W., Renda G., Neuenschwander F.C., Perez B., Reza S., Neves D., Rios A.M.P., Ria L., Neykova A., Perez-Cabezas A., Richter D., Miguel R.N., Perlman R., Rickli H., Nijmeh G., Persic V., Rieker W., Nizov A., Perticone F., Vera T.R., Campos R.N., Peters T.K., Ritt L.E., Nossan J., Petkar S., Roberts D., Novikova T., Pezo L.F., Briones I.R., Nowalany-Kozielska E., Pflucke C., Escudero A.E.R., Nsah E., Pham D.N., Pascual C.R., Fragoso J.C.N., Phillips R.T., Roman M., Nurgalieva S., Phlaum S., Romeo F., Nuyens D., Pieters D., Ronner E., Nyvad O., Pineau J., Roux J.-F., de Los Rios Ibarra M.O., Pinter A., Rozkova N., O'Donnell P., Pinto F., Rubacek M., O'Donnell M., Pisters R., Rubalcava F., Oh S., Pivac N., Russo A.M., Oh Y.S., Pocanic D., Rutgers M.P., Oh D., Podoleanu C., Rybak K., O'Hara G., Politano A., Said S., Oikonomou K., Poljakovic Z., Sakamoto T., Olivares C., Pollock S., Salacata A., Oliver R., Garcea J.P., Salem A., Ruiz R.O., Poppert H., Bodes R.S., Olympios C., Porcu M., Saltzman M.A., Omaszuk-Kazberuk A., Reino A.P., Salvioni A., Asensi J.O., Prasad N., Vallejo G.S., Fernandez M.S., Sokal A., Tu T.M., Saporito W.F., Yan Y.S.O., Tuininga Y., Sarikonda K., Sotolongo R., Turakhia M., Sasaoka T., de Souza O.F., Turk S., Sati H., Sparby J.A., Turner W., Savelieva I., Spinar J., Tveit A., Scala P.-J., Sprigings D., Tytus R., Schellinger P., Spyropoulos A.C., Valadao C., Scherr C., Stakos D., van Bergen P.F.M.M., Schmitz L., Steinwender C., van de Borne P., Schmitz K.-H., Stergiou G., van den Berg B.J., Schmitz B., Stiell I., van der Zwaan C., Schnabel T., Stoddard M., Van Eck M., Schnupp S., Stoikov A., Vanacker P., Schoeniger P., Streb W., Vasilev D., Schon N., Styliadis I., Vasilikos V., Schwimmbeck P., Su G., Vasilyev M., Seamark C., Su X., Veerareddy S., Searles G., Sudnik W., Mino M.V., Seidl K.-H., Sukles K., Venkataraman A., Seidman B., Sun X., Verdecchia P., Sek J., Swart H., Versaci F., Sekaran L., Szavits-Nossan J., Vester E.G., Serrati C., Taggeselle J., Vial H., Shah N., Takagi Y., Victory J., Shah V., Takhar A.P.S., Villamil A., Shah A., Tamm A., Vincent M., Shah S., Tanaka K., Vlastaris A., Sharma V.K., Tanawuttiwat T., Dahl J., Shaw L., Tang S., Vora K., Sheikh K.H., Tang A., Vranian R.B., Shimizu N., Tarsi G., Wakefield P., Shimomura H., Tassinari T., Wang N., Shin D.-G., Tayal A., Wang M., Shin E.-S., Tayebjee M., Wang X., Shite J., Berg J.M., Wang F., Sibilio G., Tesloianu D., Wang T., Silver F., The S.H.K., Warner A.L., Sime I., Thomas D., Watanabe K., Simmers T.A., Timsit S., Wei J., Singh N., Tobaru T., Weimar C., Siostrzonek P., Tomasik A.R., Weiner S., Smadja D., Torosoff M., Weinrich R., Smith D.W., Touze E., Wen M.-S., Snitman M., Trendafilova E., Wiemer M., Filho D.S., Tsai W.K., Wiggers P., Soda H., Tse H.F., Wilke A., Sofley C., Tsutsui H., Williams D., Williams M.L., Yan P.Y.B., Zhang P., Witzenbichler B., Yang T., Zhang J., Wong B., Yao J., Zhao S.P., Wong K.S.L., Yeh K.-H., Zhao Y., Wozakowska-Kaplon B., Yin W.H., Zhao Z., Wu S., Yotov Y., Zheng Y., Wu R.C., Zahn R., Zhou J., Wunderlich S., Zarich S., Zimmermann S., Wyatt N., Zenin S., Zini A., Wylie J., Zeuthen E.L., Zizzo S., Xu Y., Zhang H., Zong W., Xu X., Zhang D., Zukerman L.S., Yamanoue H., Zhang X., and Yamashita T.
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Apixaban ,Atrial fibrillation ,Dabigatran ,Non-vitamin K antagonists ,Rivaroxaban ,Pyridones ,Medizin ,Myocardial Infarction ,Administration, Oral ,Anticoagulants ,Hemorrhage ,General Medicine ,Non-vitamin K antagonist ,Stroke ,Clinical Trials, Phase III as Topic ,Humans ,Prospective Studies ,Registries ,Cardiology and Cardiovascular Medicine - Abstract
Background and purpose Prospectively collected data comparing the safety and effectiveness of individual non-vitamin K antagonists (NOACs) are lacking. Our objective was to directly compare the effectiveness and safety of NOACs in patients with newly diagnosed atrial fibrillation (AF). Methods In GLORIA-AF, a large, prospective, global registry program, consecutive patients with newly diagnosed AF were followed for 3 years. The comparative analyses for (1) dabigatran vs rivaroxaban or apixaban and (2) rivaroxaban vs apixaban were performed on propensity score (PS)-matched patient sets. Proportional hazards regression was used to estimate hazard ratios (HRs) for outcomes of interest. Results The GLORIA-AF Phase III registry enrolled 21,300 patients between January 2014 and December 2016. Of these, 3839 were prescribed dabigatran, 4015 rivaroxaban and 4505 apixaban, with median ages of 71.0, 71.0, and 73.0 years, respectively. In the PS-matched set, the adjusted HRs and 95% confidence intervals (CIs) for dabigatran vs rivaroxaban were, for stroke: 1.27 (0.79–2.03), major bleeding 0.59 (0.40–0.88), myocardial infarction 0.68 (0.40–1.16), and all-cause death 0.86 (0.67–1.10). For the comparison of dabigatran vs apixaban, in the PS-matched set, the adjusted HRs were, for stroke 1.16 (0.76–1.78), myocardial infarction 0.84 (0.48–1.46), major bleeding 0.98 (0.63–1.52) and all-cause death 1.01 (0.79–1.29). For the comparison of rivaroxaban vs apixaban, in the PS-matched set, the adjusted HRs were, for stroke 0.78 (0.52–1.19), myocardial infarction 0.96 (0.63–1.45), major bleeding 1.54 (1.14–2.08), and all-cause death 0.97 (0.80–1.19). Conclusions Patients treated with dabigatran had a 41% lower risk of major bleeding compared with rivaroxaban, but similar risks of stroke, MI, and death. Relative to apixaban, patients treated with dabigatran had similar risks of stroke, major bleeding, MI, and death. Rivaroxaban relative to apixaban had increased risk for major bleeding, but similar risks for stroke, MI, and death. Registration URL: https://www.clinicaltrials.gov. Unique identifiers: NCT01468701, NCT01671007. Date of registration: September 2013. Graphical abstract
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- 2022
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8. Development and implementation of the AIDA International Registry for patients with Schnitzler’s syndrome
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Sota, J, Vitale, A, Więsik-Szewczyk, E, Frassi, M, Lopalco, G, Emmi, G, Govoni, M, de Paulis, A, Marino, A, Gidaro, A, Monti, S, Opris-Belinski, D, Pereira, Rmr, Jahnz-Rózyk, K, Gaggiano, C, Crisafulli, F, Iannone, F, Mattioli, I, Ruffilli, F, Mormile, I, Rybak, K, Caggiano, V, Airò, P, Tufan, A, Gentileschi, S, Ragab, G, Almaghlouth, Ia, Aboul-Fotouh Khalil, A, Cattalini, M, La Torre, F, Tarsia, M, Giardini, Ham, Ali Saad, M, Bocchia, M, Caroni, F, Giani, T, Cinotti, E, Ruscitti, P, Rubegni, P, Dagostin, Ma, Frediani, B, Guler, Aa, Della Casa, F, Maggio, Mc, Recke, A, von Bubnoff, D, Krause, K, Balistreri, A, Fabiani, C, Rigante, Donato, Cantarini, L, Rigante D (ORCID:0000-0001-7032-7779), Sota, J, Vitale, A, Więsik-Szewczyk, E, Frassi, M, Lopalco, G, Emmi, G, Govoni, M, de Paulis, A, Marino, A, Gidaro, A, Monti, S, Opris-Belinski, D, Pereira, Rmr, Jahnz-Rózyk, K, Gaggiano, C, Crisafulli, F, Iannone, F, Mattioli, I, Ruffilli, F, Mormile, I, Rybak, K, Caggiano, V, Airò, P, Tufan, A, Gentileschi, S, Ragab, G, Almaghlouth, Ia, Aboul-Fotouh Khalil, A, Cattalini, M, La Torre, F, Tarsia, M, Giardini, Ham, Ali Saad, M, Bocchia, M, Caroni, F, Giani, T, Cinotti, E, Ruscitti, P, Rubegni, P, Dagostin, Ma, Frediani, B, Guler, Aa, Della Casa, F, Maggio, Mc, Recke, A, von Bubnoff, D, Krause, K, Balistreri, A, Fabiani, C, Rigante, Donato, Cantarini, L, and Rigante D (ORCID:0000-0001-7032-7779)
- Abstract
Objective: The present paper describes the design, development, and implementation of the AutoInflammatory Disease Alliance (AIDA) International Registry specifically dedicated to patients with Schnitzler syndrome. Methods: This is a clinical physician-driven, population- and electronic-based registry implemented for the retrospective and prospective collection of real-life data from patients with Schnitzler’s syndrome; the registry is based on the Research Electronic Data Capture (REDCap) tool, which is thought to collect standardised information for clinical research, and has been realised to change over time according to future scientific acquisitions and potentially communicate with other existing or future similar registries. Results: Since its launch, 112 centres from 23 countries in 4 continents have been involved. Fifty-four have already obtained the approval from their local Ethics Committees. The platform counts 303 users (113 Principal Investigators, 186 Site Investigators, 2 Lead Investigators, and 2 data managers) at current (April 12th 2022). The registry collects baseline and follow-up data using 3922 fields organised into 25 instruments, including patient’s demographics, history, clinical manifestations and symptoms, trigger/risk factors, laboratory, instrumental exams, therapies, socioeconomic information, and healthcare access. Conclusions: This International Registry for patients with Schnitzler syndrome facilitates standardised data collection, enabling international collaborative projects through data sharing and dissemination of knowledge; in turn, it will shed light into many blind spots characterizing this complex autoinflammatory disorder
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- 2022
9. Passive kardiovaskuläre Implantate in der Magnetresonanztomographie: Stellungnahme der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung zur Sicherheit der Magnetresonanztomographie
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Müllerleile, K., Kolb, C., Rittger, H., Rybak, K., Tillmans, C., Wiegand, U., Sechtem, U., Kelm, M., and Schulz-Menger, J.
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- 2015
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10. Curriculum Kardiologie
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Werdan, K., Baldus, St., Bauersachs, J., Baumgartner, H., Bongarth, C. M., Buerke, M., Dörr, R., Duncker, D., Eckardt, L., El-Armouche, A., Elsässer, A., Fach, A., Flachskampf, F. A., Gabelmann, M., Griebenow, R., Heinemann-Meerz, S., Hoffmeister, H. M., Katus, H. A., Kaul, N., Krämer, L.-I., Kuhn, B., Lange, T., Lehmann, L. H., Lugenbiel, P., Michels, G., Müller-Werdan, U., Oldenburg, O., Rittger, H., Rottbauer, W., Rybak, K., Sack, S., Skobel, C. E., Smetak, N., Thiele, H., Tiefenbacher, C., Tiemann, K., Voelker, W., Zeiher, A., and Frey, N.
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(Muster-)Weiterbildungsordnung ,Allgemeine Kardiologie ,Bundesärztekammer (BÄK) ,German Cardiac Society (DGK) ,Zusatz-Weiterbildung Kardiale Magnetresonanztomographie ,General cardiology ,Deutsche Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e. V. (DGK) ,German Medical Association (BÄK) ,Curriculum ,Zusatz-Weiterbildung Spezielle Kardiologie für Erwachsene mit angeborenen Herzfehlern (EMAH) ,Specialized educational program of the BÄK “Treatment of Adults with Congenital Heart Disease” ,Specialized educational program of the BÄK “Cardiac Magnetic Resonance Imaging” - Abstract
Die aktualisierte zweite Auflage des „Curriculum Kardiologie“ – Erstauflage 2013 – möchte aus Sicht der Fachgesellschaft aufzeigen, welche Kompetenzen ein Kardiologe heute beherrschen sollte. Sehr zu begrüßen ist, dass in dieser zweiten Auflage nun auch Vertreter der Young DGK als Autoren mitgearbeitet haben. Die zunehmende Spezialisierung innerhalb der Kardiologie darf dabei jedoch nur die eine Seite der Medaille darstellen: Auch weiterhin muss es ein gemeinsames Fundament der Kardiologie geben, eingebettet in das Fach „Innere Medizin“. Dieses Fundament beinhaltet den Grundstock an theoretischen Kenntnissen, an praktischen Fähigkeiten (Kompetenzlevel I–III) und an beruflich-professioneller Einstellung des (angehenden) Kardiologen. Neues für die Weiterbildung ist seit der Erstauflage des Curriculums 2013 hinzugekommen, so z. B. ein Kapitel „Digitale Kardiologie“, die neu in die Muster-Weiterbildungsordnung für den Kardiologen aufgenommene Weiterbildung in „Psychokardiologie“ und schließlich auch die explizite Formulierung der Partizipativen Entscheidungsfindung („Shared Decision Making“) im Interesse des Herzpatienten. Dem Weiterzubildenden soll das Curriculum die Möglichkeit geben, seine Weiterbildungszeit so effizient wie möglich zu strukturieren und das Erlernte anschließend im Sinne eines „berufslebenslangen“ Qualifizierens zu bewahren und auszubauen. Das Curriculum möchte aber auch die Weiterbilder und die Ärztekammern erreichen und aufzeigen, welche Inhalte und Fertigkeiten nach Ansicht der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung (DGK) in der Weiterbildung zum Kardiologen vermittelt werden sollen. Zusatzmaterial online Die Online-Version dieses Beitrags (10.1007/s12181-020-00425-w) enthält ein ausführliches Inhaltsverzeichnis, ein Abkürzungsverzeichnis und ein Literaturverzeichnis. Beitrag und Zusatzmaterial stehen Ihnen auf www.springermedizin.de zur Verfügung. Bitte geben Sie dort den Beitragstitel in die Suche ein, das Zusatzmaterial finden Sie beim Beitrag unter „Ergänzende Inhalte“.
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- 2020
11. Empfehlungen zum Telemonitoring bei Patienten mit implantierten Herzschrittmachern, Defibrillatoren und kardialen Resynchronisationssystemen
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Müller, A., Rybak, K., Klingenheben, T., Schumacher, B., Israel, C., Helms, T.M., Oeff, M., Perings, C., Sack, S., Piorkowski, C., Preissler, R., Zugck, C., and Schwab, J.O.
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- 2013
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12. Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation: The GLORIA-AF registry
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Ntaios, G., Huisman, M. V., Diener, H. -C., Halperin, J. L., Teutsch, C., Marler, S., Gurusamy, V. K., Thompson, M., Lip, G. Y. H., Olshansky, B., Abban, D. W., Abdul, N., Abud, A. M., Adams, F., Addala, S., Adragao, P., Ageno, W., Aggarwal, R., Agosti, S., Agostoni, P., Aguilar, F., Linares, J. A., Aguinaga, L., Ahmed, J., Aiello, A., Ainsworth, P., Aiub, J. R., Al-Dallow, R., Alderson, L., Aldrete Velasco, J. A., Alexopoulos, D., Manterola, F. A., Aliyar, P., Alonso, D., Alves da Costa, F. A., Amado, J., Amara, W., Amelot, M., Amjadi, N., Ammirati, F., Andrade, M., Andrawis, N., Annoni, G., Ansalone, G., Ariani, M. K., Arias, J. C., Armero, S., Arora, C., Aslam, M. S., Asselman, M., Audouin, P., Augenbraun, C., Aydin, S., Ayryanova, I., Aziz, E., Backes, L. M., Badings, E., Bagni, E., Baker, S. H., Bala, R., Baldi, A., Bando, S., Banerjee, S., Bank, A., Esquivias, G. B., Barr, C., Bartlett, M., Kes, V. B., Baula, G., Behrens, S., Bell, A., Benedetti, R., Mazuecos, J. B., Benhalima, B., Bergler-Klein, J., Berneau, J. -B., Bernstein, R. A., Berrospi, P., Berti, S., Berz, A., Best, E., Bettencourt, P., Betzu, R., Bhagwat, R., Bhatta, L., Biscione, F., Bisignani, G., Black, T., Bloch, M. J., Bloom, S., Blumberg, E., Bo, M., Bohmer, E., Bollmann, A., Bongiorni, M. G., Boriani, G., Boswijk, D. J., Bott, J., Bottacchi, E., Kalan, M. B., Bradman, D., Brautigam, D., Breton, N., Brouwers, P. J. A. M., Browne, K., Cortada, J. B., Bruni, A., Brunschwig, C., Buathier, H., Buhl, A., Bullinga, J., Cabrera, J. W., Caccavo, A., Cai, S., Caine, S., Calo, L., Calvi, V., Sanchez, M. C., Candeias, R., Capuano, V., Capucci, A., Caputo, R., Rizo, T. C., Cardona, F., Carlos da Costa Darrieux, F., Duarte Vera, Y. C., Carolei, A., Carreno, S., Carvalho, P., Cary, S., Casu, G., Cavallini, C., Cayla, G., Celentano, A., Cha, T. -J., Cha, K. S., Chae, J. K., Chalamidas, K., Challappa, K., Chand, S. P., Chandrashekar, H., Chartier, L., Chatterjee, K., Chavez Ayala, C. A., Cheema, A., Chen, L., Chen, S. -A., Chen, J. H., Chiang, F. -T., Chiarella, F., Chih-Chan, L., Cho, Y. K., Choi, J. -I., Choi, D. J., Chouinard, G., Hoi-Fan Chow, D., Chrysos, D., Chumakova, G., Jose Roberto Chuquiure Valenzuela, E. J., Nica, N. C., Cislowski, D. J., Clay, A., Clifford, P., Cohen, A., Cohen, M., Cohen, S., Colivicchi, F., Collins, R., Colonna, P., Compton, S., Connolly, D., Conti, A., Buenostro, G. C., Coodley, G., Cooper, M., Coronel, J., Corso, G., Sales, J. C., Cottin, Y., Covalesky, J., Cracan, A., Crea, Filippo, Crean, P., Crenshaw, J., Cullen, T., Darius, H., Dary, P., Dascotte, O., Dauber, I., Davalos, V., Davies, R., Davis, G., Davy, J. -M., Dayer, M., De Biasio, M., De Bonis, S., De Caterina, R., De Franceschi, T., de Groot, J. R., De Horta, J., De La Briolle, A., Topete, G. D. L. P., Vicenzo de Paola, A. A., de Souza, W., de Veer, A., De Wolf, L., Decoulx, E., Deepak, S., Defaye, P., Del-Carpio Munoz, F., Brkljacic, D. D., Deumite, N. J., Di Legge, S., Diemberger, I., Dietz, D., Dionisio, P., Dong, Q., Rossi dos Santos, F., Dotcheva, E., Doukky, R., D'Souza, A., Dubrey, S., Ducrocq, X., Dupljakov, D., Duque, M., Dutta, D., Duvilla, N., Duygun, A., Dziewas, R., Eaton, C. B., Eaves, W., Ebels-Tuinbeek, L. A., Ehrlich, C., Eichinger-Hasenauer, S., Eisenberg, S. J., El Jabali, A., El Shahawy, M., Hernandes, M. E., Izal, A. E., Evonich, R., Evseeva, O., Ezhov, A., Fahmy, R., Fang, Q., Farsad, R., Fauchier, L., Favale, S., Fayard, M., Fedele, J. L., Fedele, F., Fedorishina, O., Fera, S. R., Gomes Ferreira, L. G., Ferreira, J., Ferri, C., Ferrier, A., Ferro, H., Finsen, A., First, B., Fischer, S., Fonseca, C., Almeida, L. F., Forman, S., Frandsen, B., French, W., Friedman, K., Friese, A., Fruntelata, A. G., Fujii, S., Fumagalli, S., Fundamenski, M., Furukawa, Y., Gabelmann, M., Gabra, N., Gadsboll, N., Galinier, M., Gammelgaard, A., Ganeshkumar, P., Gans, C., Quintana, A. 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B., Kinova, E., Klein, A., Kmetzo, J. J., Kneller, G. L., Knezevic, A., Angela Koh, S. M., Koide, S., Kollias, A., Kooistra, J. A., Koons, J., Koschutnik, M., Kostis, W. J., Kovacic, D., Kowalczyk, J., Koziolova, N., Kraft, P., Kragten, J. A., Krantz, M., Krause, L., Krenning, B. J., Krikke, F., Kromhout, Z., Krysiak, W., Kumar, P., Kumler, T., Kuniss, M., Kuo, J. -Y., Kuppers, A., Kurrelmeyer, K., Kwak, C. H., Laboulle, B., Labovitz, A., Lai, W. T., Lam, A., Lam, Y. Y., Zanetti, F. L., Landau, C., Landini, G., Figueiredo, E. L., Larsen, T., Lavandier, K., Leblanc, J., Lee, M. H., Lee, C. -H., Lehman, J., Leitao, A., Lellouche, N., Lelonek, M., Lenarczyk, R., Lenderink, T., Gonzalez, S. L., Leong-Sit, P., Leschke, M., Ley, N., Li, Z., Li, X., Li, W., Lichy, C., Lieber, I., Limon Rodriguez, R. H., Lin, H., Liu, F., Liu, H., Esperon, G. L., Navarro, N. L., Lo, E., Lokshyn, S., Lopez, A., Lopez-Sendon, J. L., Lorga Filho, A. M., Lorraine, R. S., Luengas, C. A., Luke, R., Luo, M., Lupovitch, S., Lyrer, P., Ma, C., Ma, G., Madariaga, I., Maeno, K., Magnin, D., Maid, G., Mainigi, S. K., Makaritsis, K., Malhotra, R., Manning, R., Manolis, A., Manrique Hurtado, H. A., Mantas, I., Jattin, F. M., Maqueda, V., Marchionni, N., Ortuno, F. M., Santana, A. M., Martinez, J., Maskova, P., Hernandez, N. M., Matsuda, K., Maurer, T., Mauro, C., May, E., Mayer, N., Mcclure, J., Mccormack, T., Mcgarity, W., Mcintyre, H., Mclaurin, B., Medina Palomino, F. A., Melandri, F., Meno, H., Menzies, D., Mercader, M., Meyer, C., Meyer, B. J., Miarka, J., Mibach, F., Michalski, D., Michel, P., Chreih, R. M., Mikdadi, G., Mikus, M., Milicic, D., Militaru, C., Minaie, S., Minescu, B., Mintale, I., Mirault, T., Mirro, M. J., Mistry, D., Miu, N. V., Miyamoto, N., Moccetti, T., Mohammed, A., Nor, A. M., Mollerus, M., Molon, G., Mondillo, S., Moniz, P., Mont, L., Montagud, V., Montana, O., Monti, C., Moretti, L., Mori, K., Moriarty, A., Morka, J., Moschini, L., Moschos, N., Mugge, A., Mulhearn, T. J., Muresan, C., Muriago, M., Musial, W., Musser, C. W., Musumeci, F., Nageh, T., Nakagawa, H., Nakamura, Y., Nakayama, T., Nam, G. -B., Nanna, M., Natarajan, I., Nayak, H. M., Naydenov, S., Nazli, J., Nechita, A. C., Nechvatal, L., Negron, S. A., Neiman, J., Neuenschwander, F. C., Neves, D., Neykova, A., Miguel, R. N., Nijmeh, G., Nizov, A., Campos, R. N., Nossan, J., Novikova, T., Nowalany-Kozielska, E., Nsah, E., Nunez Fragoso, J. C., Nurgalieva, S., Nuyens, D., Nyvad, O., Odin de Los Rios Ibarra, M., O'Donnell, P., O'Donnell, M., Oh, S., Oh, Y. S., Oh, D., O'Hara, G., Oikonomou, K., Olivares, C., Oliver, R., Ruiz, R. O., Olympios, C., Anna, omaszuk-Kazberuk, Asensi, J. O., eena Padayattil, Jose, Padilla Padilla, F. G., Rios, V. P., Pajes, G., Pandey, A. S., Paparella, G., Paris, F., Park, H. W., Park, J. S., Parthenakis, F., Passamonti, E., Patel, R. J., Patel, J., Patel, M., Patrick, J., Jimenez, R. P., Paz, A., Pengo, V., Pentz, W., Perez, B., Perez Rios, A. M., Perez-Cabezas, A., Perlman, R., Persic, V., Perticone, F., Peters, T. K., Petkar, S., Pezo, L. F., Pflucke, C., Pham, D. N., Phillips, R. T., Phlaum, S., Pieters, D., Pineau, J., Pinter, A., Pinto, F., Pisters, R., Pivac, N., Pocanic, D., Podoleanu, C., Politano, A., Poljakovic, Z., Pollock, S., Garcea, J. P., Poppert, H., Porcu, M., Reino, A. P., Prasad, N., Precoma, D. B., Prelle, A., Prodafikas, J., Protasov, K., Pye, M., Qiu, Z., Quedillac, J. -M., Raev, D., Raffo Grado, C. A., Rahimi, S., Raisaro, A., Rama, B., Ramos, R., Ranieri, M., Raposo, N., Rashba, E., Rauch-Kroehnert, U., Reddy, R., Renda, G., Reza, S., Ria, L., Richter, D., Rickli, H., Rieker, W., Vera, T. R., Ritt, L. E., Roberts, D., Briones, I. R., Rodriguez Escudero, A. E., Pascual, C. R., Roman, M., Romeo, F., Ronner, E., Roux, J. -F., Rozkova, N., Rubacek, M., Rubalcava, F., Russo, A. M., Rutgers, M. P., Rybak, K., Said, S., Sakamoto, T., Salacata, A., Salem, A., Bodes, R. S., Saltzman, M. A., Salvioni, A., Vallejo, G. S., Fernandez, M. S., Saporito, W. F., Sarikonda, K., Sasaoka, T., Sati, H., Savelieva, I., Scala, P. -J., Schellinger, P., Scherr, C., Schmitz, L., Schmitz, K. -H., Schmitz, B., Schnabel, T., Schnupp, S., Schoeniger, P., Schon, N., Schwimmbeck, P., Seamark, C., Searles, G., Seidl, K. -H., Seidman, B., Sek, J., Sekaran, L., Serrati, C., Shah, N., Shah, V., Shah, A., Shah, S., Sharma, V. K., Shaw, L., Sheikh, K. H., Shimizu, N., Shimomura, H., Shin, D. -G., Shin, E. -S., Shite, J., Sibilio, G., Silver, F., Sime, I., Simmers, T. A., Singh, N., Siostrzonek, P., Smadja, D., Smith, D. W., Snitman, M., Filho, D. S., Soda, H., Sofley, C., Sokal, A., Oi Yan, Y. S., Sotolongo, R., Ferreira de Souza, O., Sparby, J. A., Spinar, J., Sprigings, D., Spyropoulos, A. C., Stakos, D., Steinwender, C., Stergiou, G., Stiell, I., Stoddard, M., Stoikov, A., Streb, W., Styliadis, I., Su, G., Su, X., Sudnik, W., Sukles, K., Sun, X., Swart, H., Szavits-Nossan, J., Taggeselle, J., Takagi, Y., Singh Takhar, A. P., Tamm, A., Tanaka, K., Tanawuttiwat, T., Tang, S., Tang, A., Tarsi, G., Tassinari, T., Tayal, A., Tayebjee, M., Berg, J. M. T., Tesloianu, D., The, S. H. K., Thomas, D., Timsit, S., Tobaru, T., Tomasik, A. R., Torosoff, M., Touze, E., Trendafilova, E., Tsai, W. K., Tse, H. F., Tsutsui, H., Tu, T. M., Tuininga, Y., Turakhia, M., Turk, S., Tcurner, W., Tveit, A., Tytus, R., Valadao, C., van Bergen, P. F. M. M., van de Borne, P., van den Berg, B. J., van der Zwaan, C., Van Eck, M., Vanacker, P., Vasilev, D., Vasilikos, V., Vasilyev, M., Veerareddy, S., Mino, M. V., Venkataraman, A., Verdecchia, P., Versaci, F., Vester, E. G., Vial, H., Victory, J., Villamil, A., Vincent, M., Vlastaris, A., Dahl, J. V., Vora, K., Vranian, R. B., Wakefield, P., Wang, N., Wang, M., Wang, X., Wang, F., Wang, T., Warner, A. L., Watanabe, K., Wei, J., Weimar, C., Weiner, S., Weinrich, R., Wen, M. -S., Wiemer, M., Wiggers, P., Wilke, A., Williams, D., Williams, M. L., Witzenbichler, B., Wong, B., Lawrence Wong, K. S., Wozakowska-Kaplon, B., Wu, S., Wu, R. C., Wunderlich, S., Wyatt, N., Wylie, J. J., Xu, Y., Xu, X., Yamanoue, H., Yamashita, T., Bryan Yan, P. Y., Yang, T., Yao, J., Yeh, K. -H., Yin, W. H., Yotov, Y., Zahn, R., Zarich, S., Zenin, S., Zeuthen, E. L., Zhang, H., Zhang, D., Zhang, X., Zhang, P., Zhang, J., Zhao, S. P., Zhao, Y., Zhao, Z., Zheng, Y., Zhou, J., Zimmermann, S., Zini, A., Zizzo, S., Zong, W., Zukerman, L. S., and Crea F. (ORCID:0000-0001-9404-8846)
- Abstract
Aim: The SAMe-TT2R2 score helps identify patients with atrial fibrillation (AF) likely to have poor anticoagulation control during anticoagulation with vitamin K antagonists (VKA) and those with scores >2 might be better managed with a target-specific oral anticoagulant (NOAC). We hypothesized that in clinical practice, VKAs may be prescribed less frequently to patients with AF and SAMe-TT2R2 scores >2 than to patients with lower scores. Methods and results: We analyzed the Phase III dataset of the Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF), a large, global, prospective global registry of patients with newly diagnosed AF and ≥1 stroke risk factor. We compared baseline clinical characteristics and antithrombotic prescriptions to determine the probability of the VKA prescription among anticoagulated patients with the baseline SAMe-TT2R2 score >2 and ≤ 2. Among 17,465 anticoagulated patients with AF, 4,828 (27.6%) patients were prescribed VKA and 12,637 (72.4%) patients an NOAC: 11,884 (68.0%) patients had SAMe-TT2R2 scores 0-2 and 5,581 (32.0%) patients had scores >2. The proportion of patients prescribed VKA was 28.0% among patients with SAMe-TT2R2 scores >2 and 27.5% in those with scores ≤2. Conclusions: The lack of a clear association between the SAMe-TT2R2 score and anticoagulant selection may be attributed to the relative efficacy and safety profiles between NOACs and VKAs as well as to the absence of trial evidence that an SAMe-TT2R2-guided strategy for the selection of the type of anticoagulation in NVAF patients has an impact on clinical outcomes of efficacy and safety. The latter hypothesis is currently being tested in a randomized controlled trial. Clinical trial registration: URL: https://www.clinicaltrials.gov//Unique identifier: NCT01937377, NCT01468701, and NCT01671007.
- Published
- 2021
13. Kommentar zu den neuen Leitlinien (2011) der Europäischen Gesellschaft für Kardiologie zum Management von Herz-Kreislauf-Erkrankungen in der Schwangerschaft
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Regitz-Zagrosek, V., Gohlke-Bärwolf, C., Baumgartner, H., Seeland, U., Rybak, K., Haass, M., and Nienaber, C.A.
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- 2012
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14. Follow-up nach Katheterablation von Vorhofflimmern: Erfassung der klinischen und elektrokardiographischen Effektivität
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Klingenheben, T., Bänsch, D., Butter, C., Doll, N., Geller, J.C., Israel, C.W., Lewalter, T., Piorkowski, C., Posur, W., Rybak, K., Schumacher, B., Smetak, N., Willems, S., Wolpert, C., and Eckardt, L.
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- 2011
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15. Unterbrechung antithrombotischer Behandlung (Bridging) bei kardialen Erkrankungen: Positionspapier
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Hoffmeister, H.M., Bode, C., Darius, H., Huber, K., Rybak, K., and Silber, S.
- Published
- 2010
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16. Die „Empfehlungen zur Strukturierung der Herzschrittmacher- und Defibrillatortherapie“ – was können sie leisten?: Umsetzung Strukturpapier HSM/ICD-Therapie
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Rybak, K.
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- 2010
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17. Konsensuspapier der Task Force „Brustschmerz-Ambulanz“ der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung
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Perings, S., Smetak, N., Block, M., Erdmann, E., Haan, F., Heusch, G., Rybak, K., Stopp, M., and Darius, H.
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- 2010
- Full Text
- View/download PDF
18. Kommentar zur Europäischen Leitlinie „Herzklappenerkrankungen“
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Flachskampf, F.A., Fehske, W., Reichenspurner, H., Rybak, K., and Daniel, W.G.
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- 2009
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19. Empfehlungen zur Strukturierung der Herzschrittmacher- und Defibrillatortherapie
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Hemmer, W., Rybak, K., Markewitz, A., Israel, C., Krämer, L.-I., Neuzner, J., Nowak, B., Pfeiffer, D., Schuchert, A., and Wiegand, U.
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- 2009
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20. Stellungnahme der Arbeitsgruppe Herzschrittmacher der Deutschen Gesellschaft für Kardiologie zur Sicherheit der asynchronen ventrikulären Schrittmacherstimulation
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Nowak, B., Hemmer, W., Israel, C. W., Krämer, L. I., Neuzner, J., Pfeiffer, D., Rybak, K., Schuchert, A., and Wiegand, U. K. H.
- Published
- 2006
- Full Text
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21. Curriculum Cardiology 2nd updated Edition
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Werdan, K., Baldus, St., Bauersachs, J., Baumgartner, H., Bongarth, C. M., Buerke, M., Dorr, R., Duncker, D., Eckardt, L., El-Armouche, A., Elsasser, A., Fach, A., Flachskampf, F. A., Gabelmann, M., Griebenow, R., Heinemann-Meerz, S., Hoffmeister, H. M., Katus, H. A., Kaul, N., Kramer, L. -I., Kuhn, B., Lange, T., Lehmann, L. H., Lugenbiel, P., Michels, G., Muller-Werdan, U., Oldenburg, O., Rittger, H., Rottbauer, W., Rybak, K., Sack, S., Skobel, C. E., Smetak, N., Thiele, H., Tiefenbacher, C., Tiemann, K., Voelker, W., Zeiher, A., Frey, N., Werdan, K., Baldus, St., Bauersachs, J., Baumgartner, H., Bongarth, C. M., Buerke, M., Dorr, R., Duncker, D., Eckardt, L., El-Armouche, A., Elsasser, A., Fach, A., Flachskampf, F. A., Gabelmann, M., Griebenow, R., Heinemann-Meerz, S., Hoffmeister, H. M., Katus, H. A., Kaul, N., Kramer, L. -I., Kuhn, B., Lange, T., Lehmann, L. H., Lugenbiel, P., Michels, G., Muller-Werdan, U., Oldenburg, O., Rittger, H., Rottbauer, W., Rybak, K., Sack, S., Skobel, C. E., Smetak, N., Thiele, H., Tiefenbacher, C., Tiemann, K., Voelker, W., Zeiher, A., and Frey, N.
- Abstract
The updated second edition of the Curriculum cardiology, first edition 2013, aims to show which competences a cardiologist should nowadays master. It is very pleasing that in this second edition representatives of the Young German Cardiac Society (Young DGK) have contributed as authors. The increasing specialization within cardiology should, however, only represent one side of the coin: there must also still be a common foundation of cardiology, embedded in the discipline internal medicine. This foundation includes the basis of theoretical knowledge, practical skills (competence levels I-III) and an occupational and professional attitude of the (prospective) cardiologist. New additions to the advanced training since the first edition of the curriculum in 2013 are, for example a chapter on digital cardiology, the further training in psychocardiology, which was newly introduced into the model further training regulations and finally also the explicit formulation of shared decision making in the interests of cardiac patients. The curriculum should give the prospective cardiologist the possibility to structure the further training as efficiently as possible and ultimately to retain and expand that which has been learned in the sense of a professional lifelong qualification. The curriculum also aims to reach the trainers and the Medical Councils and demonstrate which contents and skills should be mediated in the further training to become a cardiologist from the perspective of the German Cardiac Society (DGK).
- Published
- 2020
22. Stellungnahme zu den Leitlinien* zur Herzschrittmachertherapie
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Lemke, B., Rybak, K., and Wiegand, U.
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- 2003
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23. Patients with recurrent syncope and implantable loop recorder exhibit better survival than the control group without implantable loop recorder
- Author
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Perings, C, primary, Wolff, C, additional, Wilk, A, additional, Witthohn, A, additional, Voss, R, additional, and Rybak, K, additional
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- 2020
- Full Text
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24. Frequency-modulation-enhanced remote sensing
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Dubinsky, I., Rybak, K., Steinfeld, J.I., and Field, R.W.
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- 1998
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25. Quantitative disease resistance assessment by real-time PCR using the Stagonospora nodorum -wheat pathosystem as a model
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Oliver, R. P., Rybak, K., Shankar, M., Loughman, R., Harry, N., and Solomon, P. S.
- Published
- 2008
26. 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy
- Author
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Regitz-Zagrosek, V, Roos-Hesselink, JW, Bauersachs, J, Blomström-Lundqvist, C, Cífková, R, De Bonis, M, Iung, B, Johnson, MR, Kintscher, U, Kranke, P, Lang, IM, Morais, J, Pieper, PG, Presbitero, P, Price, S, Rosano, GMC, Seeland, U, Simoncini, T, Swan, L, Warnes, CA, Deaton, C, Simpson, IA, Aboyans, V, Agewall, S, Barbato, E, Calda, P, Coca, A, Coman, IM, De Backer, J, Delgado, V, Di Salvo, G, Fitzsimmons, S, Fitzsimons, D, Garbi, M, Gevaert, S, Hindricks, G, Jondeau, G, Kluin, J, Lionis, C, McDonagh, TA, Meier, P, Moons, P, Pantazis, A, Piepoli, MF, Rocca, B, Roffi, M, Rosenkranz, S, Sarkozy, A, Shlyakhto, E, Silversides, CK, Sliwa, K, Sousa-Uva, M, Tamargo, J, Thorne, S, Van de Velde, M, Williams, B, Zamorano, JL, Windecker, S, Bueno, H, Collet, J-P, Dean, V, Gaemperli, O, Jüni, P, Katus, HA, Knuuti, J, Lancellotti, P, Leclercq, C, Ponikowski, P, Richter, DJ, Hammoudi, N, Piruzyan, A, Mascherbauer, J, Samadov, F, Prystrom, A, Pasquet, A, Caluk, J, Gotcheva, N, Skoric, B, Heracleous, H, Vejlstrup, N, Maser, M, Kaaja, RJ, Srbinovska-Kostovska, E, Mounier-Vehier, C, Vakhtangadze, T, Rybak, K, Giannakoulas, G, Kiss, RG, Thrainsdottir, IS, Erwin, RJ, Porter, A, Geraci, G, Ibrahimi, P, Lunegova, O, Mintale, I, Kadri, Z, Benlamin, H, Barysiene, J, Banu, CA, Caruana, M, Gratii, C, Haddour, L, Bouma, BJ, Estensen, M-E, Hoffman, P, Petris, AO, Moiseeva, O, Bertelli, L, Tesic, BV, Dubrava, J, Koželj, M, Prieto-Arévalo, R, Furenäs, E, Schwerzmann, M, Mourali, MS, Ozer, N, Mitchenko, O, Nelson-Piercy, C, Regitz-Zagrosek, V., Roos-Hesselink, J. W., Bauersachs, J., Blomstrom-Lundqvist, C., Cifkova, R., De Bonis, M., Iung, B., Johnson, M. R., Kintscher, U., Kranke, P., Lang, I. M., Morais, J., Pieper, P. G., Presbitero, P., Price, S., Rosano, G. M. C., Seeland, U., Simoncini, T., Swan, L., Warnes, C. A., Regitz-Zagrosek, Vera, Roos-Hesselink, Jolien W, Bauersachs, Johann, Blomström-Lundqvist, Carina, Cífková, Renata, De Bonis, Michele, Iung, Bernard, Johnson, Mark Richard, Kintscher, Ulrich, Kranke, Peter, Lang, Irene Marthe, Morais, Joao, Pieper, Petronella G, Presbitero, Patrizia, Price, Susanna, Rosano, Giuseppe MC, Seeland, Ute, Simoncini, Tommaso, Swan, Lorna, Warnes, Carole A, and Cardiology
- Subjects
Counseling ,Prenatal Diagnosi ,030204 cardiovascular system & hematology ,Guideline ,Cardiovascular ,0302 clinical medicine ,Pregnancy ,Prenatal Diagnosis ,030212 general & internal medicine ,1102 Cardiorespiratory Medicine and Haematology ,Societies, Medical ,Risk assessment ,Advisory Committee ,Advisory Committees ,Cardiology ,Cardiovascular Agents ,Europe ,Female ,Humans ,Poland ,Pregnancy Complications, Cardiovascular ,Practice Guidelines as Topic ,valvular heart disease ,Cardiovascular disease ,Management ,Hypertension ,Drug therapy ,Cardiology and Cardiovascular Medicine ,Arrhythmia ,Human ,medicine.medical_specialty ,Settore BIO/14 - FARMACOLOGIA ,Cardiomyopathy ,Heart failure ,Cardiovascular therapy ,Pulmonary hypertension ,Aortic pathology ,03 medical and health sciences ,SDG 3 - Good Health and Well-being ,Medical ,medicine ,Cardiovascular diagnosis ,Intensive care medicine ,Congenital heart disease ,Pharmacology ,business.industry ,ta3121 ,medicine.disease ,Valvular heart disease ,Pregnancy Complications ,Cardiovascular System & Hematology ,Cardiovascular Agent ,Societies ,business - Published
- 2019
27. The Changing Landscape for Stroke Prevention in AF: Findings From the GLORIA-AF Registry Phase 2
- Author
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Huisman, M. V., Rothman, K. J., Paquette, M., Teutsch, C., Diener, H. -C., Dubner, S. J., Halperin, J. L., C. S., Ma, Zint, K., Elsaesser, A., Bartels, D. B., Lip, G. Y. H., Abban, D., Abdul, N., Abelson, M., Ackermann, A., Adams, F., Adams, L., Adragao, P., Ageno, W., Aggarwal, R., Agosti, S., Marin, J. A., Aguilar, F., Aguilar Linares, J. A., Aguinaga, L., Ahmad, Z., Ainsworth, P., Al Ghalayini, K., Al Ismail, S., Alasfar, A., Alawwa, A., Al-Dallow, R., Alderson, L., Alexopoulos, D., Ali, A., Ali, M., Aliyar, P., Al-Joundi, T., Al Mahameed, S., Almassi, H., Almuti, K., Al-Obaidi, M., Alshehri, M., Altmann, U., Alves, A. R., Al-Zoebi, A., Amara, W., Amelot, M., Amjadi, N., Ammirati, F., Andrawis, N., Angoulvant, D., Annoni, G., Ansalone, G., Antonescu, S. A., Ariani, M., Arias, J. C., Armero, S., Arora, R., Arora, C., Ashcraft, W., Aslam, M. S., Astesiano, A., Audouin, P., Augenbraun, C., Aydin, S., Azar, R., Azim, A., Aziz, S., Backes, L. M., Baig, M., Bains, S., Bakbak, A., Baker, S., Bakhtiar, K., Bala, R., Banayan, J., Bandh, S., Bando, S., Banerjee, S., Bank, A., Barbarash, O., Baron, G., Barr, C., Barrera, C., Barton, J., Kes, V. B., Baula, G., Bayeh, H., Bazargani, N., Behrens, S., Bell, A., Benezet-Mazuecos, J., Benhalima, B., Berdague, P., Berg van den, B. J., Bergen van, P. F. M. M., Berngard, E., Bernstein, R., Berrospi, P., Berti, S., Bertomeu, V., Berz, A., Bettencourt, P., Betzu, R., Beyer-Westendorf, J., Bhagwat, R., Black, T., Blanco Ibaceta, J. H., Bloom, S., Blumberg, E., Bo, M., Bockisch, V., Bohmer, E., Bongiorni, M. G., Boriani, G., Bosch, R., Boswijk, D. J., Bott, J., Bottacchi, E., Kalan, M. B., Brandes, A., Bratland, B., Brautigam, D., Breton, N., Brouwers, P. J. A. M., Browne, K., Bruguera, J., Brunehaut, M., Brunschwig, C., Buathier, H., Buhl, A., Bullinga, J., Butcher, K., Cabrera Honorio, J. W., Caccavo, A., Cadinot, D., Cai, S., Calvi, V., Camm, J., Candeias, R., Capo, J., Capucci, A., Cardoso, J. N., Duarte Vera, Y. C., Carlson, B., Carvalho, P., Cary, S., Casanova, R., Casu, G., Cattan, S., Cavallini, C., Cayla, G., Cha, T. J., Cha, K. S., Chaaban, S., Chae, J. K., Challappa, K., Chand, S., Chandrashekar, H., Chang, M., Charbel, P., Chartier, L., Chatterjee, K., Cheema, A., Chen, S. -A., Chevallereau, P., Chiang, F. -T., Chiarella, F., Chih-Chan, L., Cho, Y. K., Choi, D. J., Chouinard, G., Danny, Chow, H. F., Chrysos, D., Chumakova, G., Jose Roberto Chuquiure Valenzuela, E. J., Cieza-Lara, T., Nica, V. C., Ciobotaru, V., Cislowski, D., Citerne, O., Claus, M., Clay, A., Clifford, P., Cohen, S., Cohen, A., Colivicchi, F., Collins, R., Compton, S., Connors, S., Conti, A., Buenostro, G. C., Coodley, G., Cooper, M., Corbett, L., Corey, O., Coronel, J., Corrigan, J., Cotrina Pereyra, R. Y., Cottin, Y., Coutu, B., Cracan, A., Crean, P., Crenshaw, J., Crijns, H. J. G. 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O, Iglesias, I, Ikpoh, M, Imberti, D, Ince, H, Indolfi, C, Ionova, T, Ip, J, Irles, D, Iseki, H, Ismail, Y, Israel, N, Isserman, S, Iteld, B, Ivanchura, G, Iyer, R, Iyer, V, Iza Villanueva, R, Jackson Voyzey, E, Jaffrani, N, Jäger, F, Jain, M, James, M, Jamon, Y, Jang, S, Pereira Jardim, C, Jarmukli, N, Jeanfreau, R, Jenkins, R, Jiang, X, Jiang, H, Jiang, T, Jiang, N, Jimenez, J, Jobe, R, Joffe, I, Johansson, B, Jones, N, Moura Jorge, J, Jouve, B, Jundi, M, Jung, W, Jung, B, Jung, K, Kabbani, S, Kabour, A, Kafkala, C, Kajiwara, K, Kalinina, L, Kampus, P, Kanda, J, Kapadia, S, Karim, A, Karolyi, L, Kashou, H, Kastrup, A, Katsivas, A, Kaufman, E, Kawai, K, Kawajiri, K, Kazmierski, J, Keeling, P, Kerfes, G, Kerr Saraiva, J, Ketova, G, Khaira, A, Khalid, M, Khludeeva, E, Khripun, A, Kim, D, Kim, N, Kim, K, Kim, Y, Kim, J, Kinova, E, Klein, A, Kleinschnitz, C, Kmetzo, J, Kneller, G, Knezevic, A, Koch, S, Koenig, K, Angela Koh, S, Köhrmann, M, Koons, J, Korabathina, R, Korennova, O, Koschutnik, M, Kosinski, E, Kovacic, D, Kowalczyk, J, Koziolova, N, Kragten, J, Krause, L, Kreidieh, I, Krenning, B, Krishnaswamy, K, Krysiak, W, Kuck, K, Kumar, S, Kümler, T, Kuniss, M, Kuo, J, Küppers, A, Kurrelmeyer, K, Kwan, T, Kyo, E, Labovitz, A, Lacroix, A, Lam, A, Lanas Zanetti, F, Landau, C, Landini, G, Lang, W, Larsen, T, Laske, V, Lavandier, K, Law, N, Lee, M, Lee, D, Leitão, A, Lejay, D, Lelonek, M, Lenarczyk, R, Leprince, P, Lequeux, B, Leschke, M, Ley, N, Li, Z, Li, Y, Li, X, Li, W, Liang, J, Lieber, I, Lillestol, M, Limon Rodriguez, R, Lin, H, Litchfield, J, Liu, Z, Liu, X, Liu, Y, Liu, F, Liu, W, Llamas Esperon, G, Llisterri, J, Lo, T, Lo, E, Lobos, J, Lodde, B, Loiselet, P, López Sendón, J, Lorga Filho, A, Lori, I, Luo, M, Lupovitch, S, Lyrer, P, Zuhairy, H, Ma, G, Ma, H, Madariaga, I, Maeno, K, Magnin, D, Mahmood, S, Mahood, K, Maid, G, Mainigi, S, Makaritsis, K, Maldonado Villalon, J, Malhotra, R, Malik, A, Mallecourt, C, Mallik, R, Manning, R, Manolis, A, Mantas, I, Manzur Jattin, F, Marcionni, N, Marín, F, Santana, A, Martinez, J, Martinez, L, Maskova, P, Hernández, N, Matskeplishvili, S, Matsuda, K, Mavri, A, May, E, Mayer, N, Mazon, P, Mcclure, J, Mccormack, T, Mcgarity, W, Mcguire, M, Mcintyre, H, Mclaughlin, P, Mclaurin, B, Medina Palomino, F, Mehta, P, Mehzad, R, Meinel, A, Melandri, F, Mena, A, Meno, H, Menzies, D, Metcalf, K, Meyer, B, Miarka, J, Mibach, F, Michalski, D, Michel, P, Chreih, R, Mikdadi, G, Mikhail, M, Mikus, M, Milicic, D, Militaru, C, Miller, G, Milonas, C, Minescu, B, Mintale, I, Miralles, A, Mirault, T, Mistry, D, Mitchell, G, Miu, N, Miyamoto, N, Moccetti, T, Mohammed, A, Nor, A, Molina de Salazar, D, Molon, G, Molony, D, Mondillo, S, Mont, L, Moodley, R, Moore, R, Ribeiro Moreira, D, Mori, K, Moriarty, A, Morka, J, Moschos, N, Mota Gomes, M, Mousallem, N, Moya, A, Mügge, A, Mulhearn, T, Muller, J, Muresan, C, Muse, D, Musial, W, Musumeci, F, Nadar, V, Nageh, T, Nair, P, Nakagawa, H, Nakamura, Y, Nakayama, T, Nam, K, Napalkov, D, Natarajan, I, Nayak, H, Nechvatal, L, Neiman, J, Nerheim, P, Neuenschwander, F, Nishida, K, Nizov, A, Novikova, T, Novo, S, Nowalany Kozielska, E, Nsah, E, Nunez Fragoso, J, Nyvad, O, de Los Rios Ibarra, M, O'Donnell, M, O'Donnell, P, Oh, D, Oh, Y, Daniel Oh, C, O'Hara, G, Oikonomou, K, Olalla, J, Olivari, Z, Oliver, R, Olympios, C, Osborne, J, Osca, J, Osman, R, Osunkoya, A, Padanilam, B, Panchenko, E, Pandey, A, Vicenzo de Paola, A, Paraschos, A, Pardell, H, Park, H, Park, J, Parkash, R, Parker, I, Parrens, E, Parris, R, Passamonti, E, Patel, J, Patel, R, Pentz, W, Persic, V, Perticone, F, Peters, P, Petkar, S, Pezo, L, Pham, D, Cao Phai, G, Phlaum, S, Pineau, J, Pineda Velez, A, Pini, R, Pinter, A, Pinto, F, Pirelli, S, Pivac, N, Pizzini, A, Pocanic, D, Calin Podoleanu, C, Polanczyk, C, Polasek, P, Poljakovic, Z, Pollock, S, Polo, J, Poock, J, Poppert, H, Porro, Y, Pose, A, Poulain, F, Poulard, J, Pouzar, J, Povolny, P, Pozzer, D, Pras, A, Prasad, N, Prevot, S, Protasov, K, Prunier, L, Puleo, J, Pye, M, Qaddoura, F, Quedillac, J, Raev, D, Rahimi, S, Raisaro, A, Rama, B, Ranadive, N, Randall, K, Ranjith, N, Raposo, N, Rashid, H, Raters, C, Rauch Kroehnert, U, Rebane, T, Regner, S, Renzi, M, Reyes Rocha, M, Reza, S, Ria, L, Richter, D, Rickli, H, Rickner, K, Rieker, W, Rigo, F, Ripoll, T, Fonteles Ritt, L, Roberts, D, Pascual, C, Briones, I, Reyes, H, Roelke, M, Roman, M, Romeo, F, Ronner, E, Ronziere, T, Rooyer, F, Rosenbaum, D, Roth, S, Rozkova, N, Rubacek, M, Rubalcava, F, Rubanenko, O, Rubin, A, Borret, M, Rybak, K, Sabbour, H, Morales, O, Sakai, T, Salacata, A, Salecker, I, Salem, A, Salfity, M, Salguero, R, Salvioni, A, Samson, M, Sanchez, G, Sandesara, C, Saporito, W, Sasaoka, T, Sattar, P, Savard, D, Scala, P, Scemama, J, Schaupp, T, Schellinger, P, Scherr, C, Schmitz, K, Schmitz, B, Schmitz, L, Schnitzler, R, Schnupp, S, Schoeniger, P, Schön, N, Schuster, S, Schwimmbeck, P, Seamark, C, Seebass, R, Seidl, K, Seidman, B, Sek, J, Sekaran, L, Seko, Y, Sepulveda Varela, P, Sevilla, B, Shah, V, Shah, A, Shah, N, Shanes, J, Sharareh, A, Sharma, V, Shaw, L, Shimizu, Y, Shimomura, H, Shin, D, Shin, E, Shite, J, Shoukfeh, M, Shoultz, C, Silver, F, Sime, I, Simmers, T, Singal, D, Singh, N, Siostrzonek, P, Sirajuddin, M, Skeppholm, M, Smadja, D, Smith, R, Smith, D, Soda, H, Sofley, C, Sokal, A, Sotolongo, R, de Souza, O, Sparby, J, Spinar, J, Sprigings, D, Spyropoulos, A, Stakos, D, Steinberg, A, Steinwender, C, Stergiou, G, Stites, H, Stoikov, A, Strasser, R, Streb, W, Styliadis, I, Su, G, Su, X, Suarez, R, Sudnik, W, Sueyoshi, A, Sukles, K, Sun, L, Suneja, R, Svensson, P, Ziekenhuis, A, Szavits Nossan, J, Taggeselle, J, Takagi, Y, Takhar, A, Tallet, J, Tamm, A, Tanaka, S, Tanaka, K, Tang, A, Tang, S, Tassinari, T, Tayama, S, Tayebjee, M, Tebbe, U, Teixeira, J, Tesloianu, D, Tessier, P, The, S, Thevenin, J, Thomas, H, Timsit, S, Topkis, R, Torosoff, M, Touze, E, Traissac, T, Trendafilova, E, Troyan, B, Tsai, W, Tse, H, Tsutsui, H, Tsutsui, T, Tuininga, Y, Turakhia, M, Turk, S, Turner, W, Tveit, A, Twiddy, S, Tytus, R, Ukrainski, G, Valdovinos Chavez, S, Van De Graaff, E, Vanacker, P, Vardas, P, Vargas, M, Vassilikos, V, Vazquez, J, Venkataraman, A, Verdecchia, P, Vester, E, Vial, H, Vinereanu, D, Vlastaris, A, Vogel, C, vom Dahl, J, von Mering, M, Vora, K, Wakefield, P, Walia, J, Walter, T, Wang, M, Wang, N, Wang, F, Wang, X, Wang, Z, Wang, K, Watanabe, K, Wei, J, Weimar, C, Weinrich, R, Wen, M, Wheelan, K, Wicke, J, Wiemer, M, Wild, B, Wilke, A, Willems, S, Williams, M, Williams, D, Winkler, A, Wirtz, J, Witzenbichler, B, Wong, D, Lawrence Wong, K, Wong, B, Wozakowska Kaplon, B, Wu, Z, Wu, S, Wyatt, N, Xu, Y, Xu, X, Yamada, A, Yamamoto, K, Yamanoue, H, Yamashita, T, Bryan Yan, P, Yang, Y, Yang, T, Yao, J, Yarlagadda, C, Yeh, K, Yotov, Y, Yvorra, S, Zahn, R, Zamorano, J, Zanini, R, Zarich, S, Zebrack, J, Zenin, S, Zeuthen, E, Zhang, X, Zhang, Q, Zhang, D, Zhang, H, Zhao, S, Zhao, X, Zheng, Y, Zheng, Q, Zhou, J, Zimmermann, S, Zimmermann, R, Zukerman, L, and Zwaan van der, C
- Subjects
Male ,oral anticoagulation ,Internationality ,Middle Aged ,registry ,Antithrombins ,Dabigatran ,Stroke ,Cross-Sectional Studies ,Fibrinolytic Agents ,Humans ,Female ,atrial fibrillation ,Prospective Studies ,Registries ,Cardiology and Cardiovascular Medicine ,Aged ,Atrial Fibrillation - Abstract
Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non–vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients’ baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age ≥75 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score ≥2; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701)
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- 2017
28. 3049Equally high detection rates of atrial fibrillation in patients after a TIA and stroke by systematic ECG monitoring with an implanted device: SPIDER-AF study
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Goss, F, primary, Rybak, K, additional, Seige, M, additional, Haerer, W, additional, Schuetz, B, additional, Mitusch, R, additional, Mueller, M, additional, Heinrich, U, additional, Stoehring, R, additional, Turschner, O, additional, Knapp, A, additional, Jauernig, M, additional, Drexler, M, additional, and Bosch, R, additional
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- 2019
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29. The effects of electron beam radiation on material properties and degradation of commercial PBAT/PLA blend
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Iuliano, A., primary, Nowacka, M., additional, Rybak, K., additional, and Rzepna, M., additional
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- 2019
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30. Drying Kinetics and Quality of Dehydrated Cranberries Pretreated by Traditional and Innovative Techniques
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Wiktor, A., primary, Nowacka, M., additional, Anuszewska, A., additional, Rybak, K., additional, Dadan, M., additional, and Witrowa‐Rajchert, D., additional
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- 2019
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31. 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy
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Deaton, C, Simpson, Ia, Aboyans, V, Agewall, S, Barbato, E, Calda, P, Coca, A, Coman, Im, De Backer, J, Delgado, V, Di Salvo, G, Fitzsimmons, S, Fitzsimons, D, Garbi, M, Gevaert, S, Hindricks, G, Jondeau, G, Kluin, J, Lionis, C, Mcdonagh, Ta, Meier, P, Moons, P, Pantazis, A, Piepoli, Mf, Rocca, Bianca, Roffi, M, Rosenkranz, S, Sarkozy, A, Shlyakhto, E, Silversides, Ck, Sliwa, K, Sousa-Uva, M, Tamargo, J, Thorne, S, Van de Velde, M, Williams, B, Zamorano, Jl, Windecker, S, Bueno, H, Collet, Jp, Dean, V, Gaemperli, O, Iung, B, Jüni, P, Katus, Ha, Knuuti, J, Lancellotti, P, Leclercq, C, Ponikowski, P, Richter, Dj, Hammoudi, N, Piruzyan, A, Mascherbauer, J, Samadov, F, Prystrom, A, Pasquet, A, Caluk, J, Gotcheva, N, Skoric, B, Heracleous, H, Vejlstrup, N, Maser, M, Kaaja, Rj, Srbinovska-Kostovska, E, Mounier-Vehier, C, Vakhtangadze, T, Rybak, K, Giannakoulas, G, Kiss, Rg, Thrainsdottir, I, Erwin, Rj, Porter, A, Geraci, G, Ibrahimi, P, Lunegova, O, Mintale, I, Kadri, Z, Benlamin, H, Barysiene, J, Banu, Ca, Caruana, M, Gratii, C, Haddour, L, Bouma, Bj, Estensen, Me, Hoffman, P, Petris, Ao, Moiseeva, O, Bertelli, L, Tesic, Bv, Dubrava, J, Koželj, M, Prieto-Arévalo, R, Furenäs, E, Schwerzmann, M, Mourali, M, Ozer, N, Mitchenko, O, Nelson-Piercy, C., Rocca B (ORCID:0000-0001-8304-6423), Deaton, C, Simpson, Ia, Aboyans, V, Agewall, S, Barbato, E, Calda, P, Coca, A, Coman, Im, De Backer, J, Delgado, V, Di Salvo, G, Fitzsimmons, S, Fitzsimons, D, Garbi, M, Gevaert, S, Hindricks, G, Jondeau, G, Kluin, J, Lionis, C, Mcdonagh, Ta, Meier, P, Moons, P, Pantazis, A, Piepoli, Mf, Rocca, Bianca, Roffi, M, Rosenkranz, S, Sarkozy, A, Shlyakhto, E, Silversides, Ck, Sliwa, K, Sousa-Uva, M, Tamargo, J, Thorne, S, Van de Velde, M, Williams, B, Zamorano, Jl, Windecker, S, Bueno, H, Collet, Jp, Dean, V, Gaemperli, O, Iung, B, Jüni, P, Katus, Ha, Knuuti, J, Lancellotti, P, Leclercq, C, Ponikowski, P, Richter, Dj, Hammoudi, N, Piruzyan, A, Mascherbauer, J, Samadov, F, Prystrom, A, Pasquet, A, Caluk, J, Gotcheva, N, Skoric, B, Heracleous, H, Vejlstrup, N, Maser, M, Kaaja, Rj, Srbinovska-Kostovska, E, Mounier-Vehier, C, Vakhtangadze, T, Rybak, K, Giannakoulas, G, Kiss, Rg, Thrainsdottir, I, Erwin, Rj, Porter, A, Geraci, G, Ibrahimi, P, Lunegova, O, Mintale, I, Kadri, Z, Benlamin, H, Barysiene, J, Banu, Ca, Caruana, M, Gratii, C, Haddour, L, Bouma, Bj, Estensen, Me, Hoffman, P, Petris, Ao, Moiseeva, O, Bertelli, L, Tesic, Bv, Dubrava, J, Koželj, M, Prieto-Arévalo, R, Furenäs, E, Schwerzmann, M, Mourali, M, Ozer, N, Mitchenko, O, Nelson-Piercy, C., and Rocca B (ORCID:0000-0001-8304-6423)
- Abstract
Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in selecting the best management strategies for an individual patient with a given condition. Guidelines and their recommendations should facilitate decision making of health professionals in their daily practice. However, the final decisions concerning an individual patient must be made by the responsible health professional(s) in consultation with the patient and caregiver as appropriate.
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- 2018
32. Novel sources of resistance to septoria nodorum blotch in the Vavilov wheat collection identified by GWAS
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Phan, H., Rybak, K., Bertazzoni, S., Furuki, E., Dinglasan, E., Hickey, L., Oliver, R., Tan, Kar-Chun, Phan, H., Rybak, K., Bertazzoni, S., Furuki, E., Dinglasan, E., Hickey, L., Oliver, R., and Tan, Kar-Chun
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- 2018
33. Novel sources of resistance to Septoria nodorum blotch in the Vavilov wheat collection identified by genome-wide association studies
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Phan, H., Rybak, K., Bertazzoni, S., Furuki, E., Dinglasan, E., Hickey, L., Oliver, R., Tan, Kar-Chun, Phan, H., Rybak, K., Bertazzoni, S., Furuki, E., Dinglasan, E., Hickey, L., Oliver, R., and Tan, Kar-Chun
- Abstract
The fungus Parastagonospora nodorum is the causal agent of Septoria nodorum blotch (SNB) of wheat. The pathosystem is mediated by multiple fungal necrotrophic effector–host sensitivity gene interactions that include SnToxA–Tsn1, SnTox1–Snn1, and SnTox3–Snn3. A P. nodorum strain lacking SnToxA, SnTox1, and SnTox3 (toxa13) retained wild-type-like ability to infect some modern wheat cultivars, suggesting evidence of other effector-mediated susceptibility gene interactions or the lack of host resistance genes. To identify genomic regions harbouring such loci, we examined a panel of 295 historic wheat accessions from the N. I. Vavilov Institute of Plant Genetic Resources in Russia, which is comprised of genetically diverse landraces and breeding lines registered from 1920 to 1990. The wheat panel was subjected to effector bioassays, infection with P. nodorum wild type (SN15) and toxa13. In general, SN15 was more virulent than toxa13. Insensitivity to all three effectors contributed significantly to resistance against SN15, but not toxa13. Genome-wide association studies using phenotypes from SN15 infection detected quantitative trait loci (QTL) on chromosomes 1BS (Snn1), 2DS, 5AS, 5BS (Snn3), 3AL, 4AL, 4BS, and 7AS. For toxa13 infection, a QTL was detected on 5AS (similar to SN15), plus two additional QTL on 2DL and 7DL. Analysis of resistance phenotypes indicated that plant breeders may have inadvertently selected for effector insensitivity from 1940 onwards. We identify accessions that can be used to develop bi-parental mapping populations to characterise resistance-associated alleles for subsequent introgression into modern bread wheat to minimise the impact of SNB.
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- 2018
34. The quality and safety of food contact materials – paper and cardboard coated with paraffin emulsion
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Nowacka, M., primary, Rybak, K., additional, Wiktor, A., additional, Mika, A., additional, Boruszewski, P., additional, Woch, J., additional, Przybysz, K., additional, and Witrowa-Rajchert, D., additional
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- 2018
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35. Idiopatic facial nerve palsy in pregnancy – facts and myths
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Rzepakowska, Anna, primary, Rybak, K, additional, Niemczyk, Kazimierz, additional, and Rybak, P, additional
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- 2018
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36. The Changing Landscape for Stroke Prevention in AF: Findings From the GLORIA-AF Registry Phase 2
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Huisman, M, Rothman, K, Paquette, M, Teutsch, C, Diener, H, Dubner, S, Halperin, J, Ma, C, Zint, K, Elsaesser, A, Bartels, D, Lip, G, Abban, D, Abdul, N, Abelson, M, Ackermann, A, Adams, F, Adams, L, Adragão, P, Ageno, W, Aggarwal, R, Agosti, S, Marin, J, Aguilar, F, Aguilar Linares, J, Aguinaga, L, Ahmad, Z, Ainsworth, P, Al Ghalayini, K, Al Ismail, S, Alasfar, A, Alawwa, A, Al Dallow, R, Alderson, L, Alexopoulos, D, Ali, A, Ali, M, Aliyar, P, Al Joundi, T, Al Mahameed, S, Almassi, H, Almuti, K, Al Obaidi, M, Alshehri, M, Altmann, U, Alves, A, Al Zoebi, A, Amara, W, Amelot, M, Amjadi, N, Ammirati, F, Andrawis, N, Angoulvant, D, Annoni, G, Ansalone, G, Antonescu, S, Ariani, M, Arias, J, Armero, S, Arora, R, Arora, C, Ashcraft, W, Aslam, M, Astesiano, A, Audouin, P, Augenbraun, C, Aydin, S, Azar, R, Azim, A, Aziz, S, Backes, L, Baig, M, Bains, S, Bakbak, A, Baker, S, Bakhtiar, K, Bala, R, Banayan, J, Bandh, S, Bando, S, Banerjee, S, Bank, A, Barbarash, O, Barón, G, Barr, C, Barrera, C, 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Zhang, H, Zhao, S, Zhao, X, Zheng, Y, Zheng, Q, Zhou, J, Zimmermann, S, Zimmermann, R, Zukerman, L, Zwaan van der, C, Zwaan van der, C., and ANNONI, GIORGIO
- Abstract
Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non–vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients’ baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age ≥75 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score ≥2; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients rece
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- 2017
37. A functionally conserved Zn2 Cys6 binuclear cluster transcription factor class regulates necrotrophic effector gene expression and host-specific virulence of two major Pleosporales fungal pathogens of wheat.
- Author
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Rybak, K., See, Pao Theen, Phan, Huyen Phan, Syme, Robert, Moffat, Caroline, Oliver, Richard, Tan, Kar-Chun, Rybak, K., See, Pao Theen, Phan, Huyen Phan, Syme, Robert, Moffat, Caroline, Oliver, Richard, and Tan, Kar-Chun
- Abstract
The fungus Parastagonospora nodorum is the causal agent of Septoria nodorum blotch of wheat (Triticum aestivum). The interaction is mediated by multiple fungal necrotrophic effector-dominant host sensitivity gene interactions. The three best-characterized effector-sensitivity gene systems are SnToxA-Tsn1, SnTox1-Snn1 and SnTox3-Snn3. These effector genes are highly expressed during early infection, but expression decreases as the infection progresses to tissue necrosis and sporulation. However, the mechanism of regulation is unknown. We have identified and functionally characterized a gene, referred to as PnPf2, which encodes a putative zinc finger transcription factor. PnPf2 deletion resulted in the down-regulation of SnToxA and SnTox3 expression. Virulence on Tsn1 and Snn3 wheat cultivars was strongly reduced. The SnTox1-Snn1 interaction remained unaffected. Furthermore, we have also identified and deleted an orthologous PtrPf2 from the tan spot fungus Pyrenophora tritici-repentis which possesses a near-identical ToxA that was acquired from P. nodorum via horizontal gene transfer. PtrPf2 deletion also resulted in the down-regulation of PtrToxA expression and a near-complete loss of virulence on Tsn1 wheat. We have demonstrated, for the first time, evidence for a functionally conserved signalling component that plays a role in the regulation of a common/horizontally transferred effector found in two major fungal pathogens of wheat.
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- 2017
38. Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry
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W., Chlewicka, I., Brodzicki, P., Stasiuk, T., Szalkowski, P., Kulig, W., Maliszewski, M., Krolicka, K., Zdrojewska, J., Nikodemska, I., Szpak, A., Wrebiak-Trznadel, M., Prokop, A., Szulc, M., Olszewski, A., Kepa, W., Banach, J., Weglarz, M., Galuszka-Bilinska, A., Krolak, A., Cisowska-Drozd, E., Orzechowski, K., Jezewska, M., Adamaszek, K., Glanowska, G., Pitsch, T., Matuszewska, G., Nowowiejska-Wiewiora, A., Deren, M., Walawski, G., Soltysiak, M., Wysocki, R., Jarosinski, G., Drzewiecka, A., Lugowski, T., Jankowska, A., Blaszczak, P., Drozd, J., Lotocka, E., Duchowska, R., Sobczyk, D., Jarmuzek, P., Sidor, M., Adamczyk-Kot, D., Sudnik, J., Cygler, J., Skoczylas, I., Poprawa, B., Kisiel, L., Kossowska, U., Sikorska-Buczkowska, B., Modzelewska, K., Demianiuk, B., Streb, W., Mularek-Kubzdela, T., Bogdanski, P., Kazmierczak, E., Zimolag, R., Lorenc, J., Furtak, R., Regulska, A., Winter, M., Fic, M., Turek, P., Nowicka, E., Bryl, W., Lenartowska, L., Jerzykowska, O., Mackow, M., Gadzinski, W., Kacorzyk, R., Zalewska, D., Sadlowski, R., Slaboszewska, J., Gruchala, M., Frankiewicz, A., Walczewska, J., Adamkiewicz-Piejko, A., Chyrek, R., Jankowska, L., Correia, A., Girao, A., Herdade, A., Sequeira, A., Tavares E Taveira, A., Gonzaga, A., Ribeiro, A., Albuquerque, A., Fernandes, A., Estriga, A., Rocha De Almeida, A., Lourenco, A., Pereira, A., Faria, A., Carvalho De Moura, B., Camossa, C., Alves, C., Aguiar, C., Rodrigues, C., Wellenkamp, E., Lins, E., Fernandes De Sousa, F., Moreira Pinto, F., Matias, F., Silva Alves, G., Braganca, G., Proenca, G., Pego, G., Vinhas, H., Arroja, I., Rosa Pais, J., Silva E Sa, J., Vasconcelos, J., Matos, J., Freitas, J., Ferreira, J., Costa, J., Alcaravela, J., Mimoso, J., Antunes, J., Ferreira Dos Santos, J., Nobre Dos santos, J., Tito Martins, J., Fernandes, J., Chambel De Aguiar, J., Moreira, J., Carvalho, J., Forte De Carvalho, J., Calaca, J., Simoes, L., Lopes Antunes, L., Soares, L., Semedo, L., Macedo, L., Sargento, L., Basto, L., Carpinteiro, L., Rebelo, L., Oliveira, L., Catarino Carvalho, M., Alves Costa, M., Gamboa, M. C., Ferrao E Vasconcelos, M. F., Custodio, M. H., Mendonca, M. I., Pinto Vaz, M. J., Espiga De Macedo, M., Lazaro, M., Martins Oliveira, M., Pelicano, N., Lousada, N., Rodrigues, O., Matos Dias, P., Fonseca, P. F., Ferreira, P., Abreu, P. E., Monteiro, P., Seabra Gomes, R., Carvalho, R., Santos, R., Pires Pereira, R., Rosado Soares, R., Baptista, S., Reis Monteiro, S., Gil, V., Sanfins, V., Martins, V., Anghel, M., Arsenescu Georgescu, C., Babes, K., Banu, M., Beyer, R., Bratu, I., Bumbu, A., Capalneanu, R., Chioncel, O. D., Chiscaneanu, T., Christodorescu, R., Cindea Nica, N., Cinteza, M., Coman, S., Constantinescu, M., Craiu, E., Dan, G. A., Dan, D. C., Dan, A., David, C. M., Dorobantu, M., Farcas, D., Firastrau, V., Florescu, C., Ghicu, A., Giuca, A., Grigoriu, R., Ionescu, D. A., Ionescu, D. D., Iosipescu, L. C., Ivan, M. V., Lighezan, D., Magheru, S., Magherusan, M., Marinescu, S. M., Motoc, A. C., Musetescu, R., Rau, M., Rotaru, L., Rus, H., Sirbu, O., Sorodoc, L., Spinu, C. M., Stanciulescu, G., Statescu, C., Toringhibel, M., Trambitas, R., Trocan, N., Tudose, A., Vinereanu, D., Zagreanu, M., Dymova, D., Semenova, N., Zherebtsova, A., Fedoskin, V., Gurianova, N., Bolotova, N., Knyazeva, V., Spitsina, T., Sytilina, N., Atamanchuk, N., Giorgadze, M., Zarechnova, S., Kutuzova, S., Sharapova, Y., Stelmakh, I., Sinyukova, O., Rostik, S., Evtukhova, L., Sukhanova, L., Makhieva, T., Tereshko, S., Kolesnikov, V., Kochurov, E., Marchenko, B., Nurgalieva, S., Galeeva, Z., Andreicheva, E., Zakirova, V., Baleeva, L., Minsafina, A., Borodina, N., Arkhipova, Y., Krechunova, T., Scherbak, M., Merkhi, A., Aksyutina, N., Ratovskaya, O., Suglobova, E., Kozhelenko, Y., Potapova, E., Poluyanova, G., Naberezhnova, N., Daniels, E., Atueva, K., Tsaryabina, L., Kurekhyan, A., Khishova, N., Dubinina, E., Demina, O., Mochkina, P., Bukanina, E., Tolpygina, S., Polyanskaya, Y., Malysheva, A., Kheliya, T., Serazhim, A., Voronina, V., Lukina, Y., Dubinskaya, R., Dmitrieva, N., Kuzyakina, M., Khartova, N., Bokuchava, N., Smirnova, E., Esenokova, A., Pavlova, Y., Smirnova, O., Astrakhantseva, P., Bykovskaya, S., Charikova, O., Berdnik, K., Karaseva, T., Zhabina, L., Oleinikova, N., Dzhkha, O., Grigoryan, S., Yakovenko, E., Ivaschenko, T., Kiseleva, I., Shokina, T., Novikova, M., Khodanov, A., Popova, L., Latyntseva, L., Kilaberiya, O., Makarenkova, K., Nosova, N., Gerasimova, T., Boikova, L., Sharapova, N., Kulikova, Y., Pasechnaya, N., Bulakhova, E., Kurochkina, S., Bratishko, I., Likhobabina, O., Panova, E., Voronina, N., Bizyaeva, N., Gusev, O., Nevolina, N., Arsentieva, T., Budanova, I., London, E., Melnikova, Khripun, A., Polyaeva, L., Osadchuk, E., Krasnoslobodskaya, O., Yakimova, N., Lugin, A., Sosnova, Y., Il'ina, E., Kositsina, G., Shanina, I., Kostomarova, S., Malgina, M., Omelchenko, M., Gorlova, I., Eidelman, S., Salakhova, A., Bondarenko, B., Sopia, R., Baboshina, N., Eliseeva, N., Tumarov, F., Petrochenko, N., Khudina, I., Arabadzhi, N., Samakhovets, V., Tkhorzhevskaya, L., Sinotova, T., Zherlitsyna, E., Minkin, S., Petrova, N., Tikhonov, Y., Shmakova, N., Abduvalieva, V., Kuzmicheva, M., Nikolaeva, L., Varezhnikova, O., Dmitrieva, T., Mikhailova, E., Yanina, Y., Kapustina, L., Vazhdaeva, Z., Golovina, G., Fedorova, N., Nikolaeva, I., Fillipova, O., Gareeva, L., Tuktarova, F., Khmelevskikh, N., Karnot, V., Golub, M., Surovtseva, I., Kulygina, V., Shelomova, N., Kruglova, I., Pokrovskaya, I., Rodina, O., Polkina, L., Biryukova, N., Filippova, E., Kotova, E., Ignatieva, T., Alekseeva, T., Gruznykh, L., Mozerova, E., Moksyuta, E., Kosachek, E., Srtumilenko, N., Baranova, O., Voronova, T., Bayakhchan, L., Grudtsina, I., Gorshkova, L., Shamsutdinova, O., Getman, M., Gorodilova, I., Karnaukhova, N., Rotenberger, V., Isaeva, L., Lebischak, G., Ryzhkova, V., Usoltseva, E., Mescharekova, D., Tavlueva, E., Mineeva, E., Stikhurova, M., Kosareva, L., Grechishkina, O., Nikishina, S., Ilyukhina, A., Gureeva, O., Soin, I., Erofeev, S., Lebedev, S., Kudryavtsev, L., Gamzatov, E., Maximchuk, N., Grekhova, L., Kolevatova, L., Kazakovtseva, M., Kolesova, O., Zharikova, L., Kukaleva, V., Starostina, N., Grushetskaya, I., Kazachkova, V., Pashentseva, I., Shimonenko, S., Sirazov, I., Chernozemova, A., Golubeva, O., Mingalaeva, S., Zatsarina, E., Kozlov, D., Davydova, N., Larina, O., Fayez Al-Habib, K., Al-Hersi, A., Al-Baker, H., Al-Faleh, H., Moberik, A., Radwan Arafah, M., Al-Shamiri, M., El-Shaer, F., Al Zaibag, M., Bdeir, M., Suliman, I., Mukhtar, A., Omar, H., Jamiel, A., Elkrail, A., Alanazy, M., Habab, M., Ashmak, K., Nourallah, R., Mak, K. H., Singh, B., Baldev, S., Chee, T. S., Koo, C. C., Low, L. P., Nair, V. P., K. S., Ng, Quek, S. S. S., Tan, E. H. M., A. L. R., Ng, Chuang, H. H., Kaliska, G., Murin, J., Hatalova, K., Gaspar, L., Simkova, I., Dubrava, J., Pjontek, J., Pella, D., Banikova, A., Szentivanyi, M., Kovar, F., Benacka, J., Gonos, I., Fazekas, F., Kycina, P., Poles, J., Pernat, A., Veternik, A., Cernic-Suligoj, N., Kerbev, M., Krajnc, I., Zagozen, P., Alam, A., Brown, B., Luke, B., Variava, E., Nethononda, R., Joubert, S., Matthews, P., Nkombua, L., Antia, V., Bhayat, J., George, S. K., Ranjith, N., Vawda, G. H. M., Govender, S., Soosiwala, I., Shein, K., Panajatovic, M., Flores, J., Khan, M. S. H., Blignaut, S., Coetzee, K., Burgess, L., Freeman, V., Theron, H. D., Arnau Vives, M. A., Abardia Oliva, F. J., Albero Martinez, V., Alegret Colomer, J. M., Alegria Ezquerra, E., Almeida Fernandez, C. A., Alvarenga Recalde, N., Alvarez Aunon, A., Alvarez Garcia, P., Amo Fernandez, C., Amoros Galito, C., Ancin Viguiristi, R., Antona Makoshi, J., Aparici Feal, M., Ardiaca Capell, A., Arnedillo Pardo, J., Arquero Garcia, G., Arrarte Esteban, V., Baquero Alonso, M., Barahona Perez, P., Bardaji Mayor, J. L., Barriales Alvarez, V., Batalla Celorio, A., Bierge Valero, D., Blanco Castineiras, J., Bosa Ojeda, F., Botana Penas, C., Brufau Redondo, H., Bruguera Cortada, J., Cabau Rubies, J., Cabrera Sole, R., Calvo Iglesias, F., Cantabrana Miguel, S., Carrillo Cardoso, R., Casanovas Pie, M., Casas Gimenez, P., Castillo Luena, E., Castillo Moreno, J. A., Castillo Orive, M., Chirivella Gonzalez, A., Chopo Alcubilla, J. M., Climent Paya, V., Cobos Gil, M. A., Colomer Martin, J. L., Concepcion Clemente, A., Cortes Sanchez, R., Cremer Luengo, D., Darnes Soler, S., de Andres Novales, J., De Castro Aritmendiz, R., Delgado Prieto, J. L., Diaz Diaz, J. L., Escobar Cervantes, C., Ezcurdia Sasieta, J., Facila Rubio, L., Falces Salvador, C., Federico Zaragoza, P., Fernandez Alvarez, R., Fernandez de la Cigona, F., Fernandez Lazaro, L. A., Fernandez Leoz, L. C., Fernandez Mouzo, R., Fernandez-Valls Gomez, M., Ferreiro Rodriguez, B., Franco Aranda, C., Freire Corzo, J., Fuertes Alonso, J., Fuertes Beneitez, J., Galve Basilio, E., Garcia Garcia, C., Garcia Gonzalez, M. J., Garcia Ortego, S., Garcia Saavedra, V., Garcia-Moll Marimon, J., Gascuena Rubia, R., Gentille Lorente, D., Gervas Pavon, H., Gilabert Gomez, R., Gomez Barrado, J. J., Gomez Doblas, J. J., Gomez Martinez, M. J., Gonzalez Juanatey, C., Gonzalez Toda, V., Gonzalvez Ortega, M., Gordillo Higuero, E., Hernandez Afonso, J., Herrera Fernandez, D., Homs Espinach, E., Idoate Gastearena, A., Irurita Latasa, M., Izquierdo Gonzalez, R., Jaquet Herter, M., Lagares Carballo, M., Lastra Galan, J. A., Limeres Gonzalez, B., Lopez Aranda, M. A., Lopez Barreiro, L., Lopez Gomez, D., Lopez Granados, A., Lopez Mourino, V., Lopez-Sendon, J. L., Mainar Latorre, L., Marin Araez, E., Marin Ortuno, F., Martin Santana, A., Martinez Florez, J., Martinez Gonzalez, J., Martinez Rivero, J. F., Marzal Martin, D., Mazzanti Mignaqui, G. F., Melero Pita, A., Molina Laborda, E., Montero Gaspar, M. A., Mora Robles, J., Morales Gonzalez, J., Moreno Arribas, J., Moreno Casquete, M. T., Moro Lopez, J. A., Moya Lopez, C., Murga Eizagaechevarria, N., Narro Garcia, F., Navarro Manchon, J., Navas Navas, C., Novo Garcia, E., Nunez Gamero, J. A., Ordonez Espana, A., Ortiz de Murua Lopez, J. A., Orts Soler, E., Otero Chulian, E., Pastor Torres, L., Paule Sanchez, A. J., Paz Bermejo, M. A., Pena Perez, G., Perea Egido, J. A., Perez de Isla, L., Perez Ibiricu, S., Perez Martinez, M. A., Perez Paredes, M., Peris Domingo, E., Pinar Sopena, J., Pindado Rodriguez, C., Pinilla Lozano, M. J., Pinero Ramirez, C., Porras Ramos, Y., Ramos Ariznabarreta, F., Rayo Gutierrez, M., Roca Catalan, J. M., Rodriguez Almodovar, A., Rodriguez Collado, J., Rodriguez Fernandez, A., Rodriguez Fernandez, J. A., Rodriguez Hernandez, J. A., Rodriguez Tejero, I., Romeo Castillejo, I., Romero Alvira, D., Romero Hinojosa, J. A., Romero Menor, C., Rossi Sevillano, P., Rueda Calle, E. C., Rueda Soriano, J., Ruiz Perez, P., Sagastagoitia Gorostiza, T., Sainz Hidalgo, I., Sandin Rollan, M., Santaolalla Rodriguez, S., Santas Olmeda, E., Santos Iglesias, J. L., Sanz Rodriguez, M. L., Segura Laborda, I., Serrano Garcia, S., Sevilla Toral, B., Silva Melchor, L., Simarro Martin-Ambrioso, E., Sola Casado, R., Soriano Navarro, C., Soto Ruiz, M. I., Talavera Calle, P., Torres Diaz, P. L., Troncoso Gil, A., Trujillo Berraquero, F., Ulecia Martinez, M. A., Umaran Sanchez, J., Vaticon Herreros, C., Vazquez Garcia, A., Vega Barbado, J. L., Velasco Espejo-Saavedra, E., Vicente Vera, T., Vida Gutierrez, M., Villar Mariscal, C., Vives Bonato, G., Wu Amen, L., Yanes Bowden, G., Yanez Wonenburger, J. C., Zamorano Gomez, J. L., Zarauza Navarro, J., Monnier, P., Forclaz, A., Grobety, M., Schlueter, L., Vuille, C., Nacht, C. A., Evequoz, D., Ciaroni, S., Domine, F., Berube, J., Hellermann, J., Koller, R., Bourgeois, G., Engel, R., Niederberger, C., Stadler, P., Gnadinger, M., Schmied, C., Wettstein, T., Badorff, C., Hilti, P., Chetelat, C. A., Sepulcri, F., Brunner, H., Schindler, J., Kraus, M., Gmur, W., Bouranasompop, C., Jiraroj-ungkun, W., Lapanun, W., Vivekaphirat, V., Panpunnung, S., Dutsadeevettakul, S., Tasneeyapant, S., Ngamjanyaporn, P., Apitamsuntorn, S., Tantisiriwat, W., Suithichaiyakul, T., Kuanprasert, S., Wongcharoen, W., Phrommintikul, A., Musigchai, C., Chantrarat, T., Uerojanaungkul, P., Apinyasawat, S., Tangcharoen, T., Lertnantakul, M., Wasuwat, A., Harinasuta, J., See, O., Chaithiraphan, V., Boonyasirinant, T., Boonyapisit, W., Kittipovanonth, M., Buakhamsri, A., Piyayotai, D., Hutayanon, P., Junejo, S., Aiyegbayo, O., Ancliff, H., Bradshaw, C., Cervenak, R., Choi, H., George, E., Gilmour, I., Gough, D., Idrissi-Sbai, A., Ingham, J., Al-Khalidi, B., Liston, A., Mackrell, J., Pattison, I., Ramachandran, R., Ray, N., Reddy, G., Sen, I., Shetty, K., Singh, L., Stanley, M., Wallace, A., Weatherhead, M., Gilbert, T., McCansh, G., Higgins, S., Killeen, C., Cromarty, I., Franklin, P., Pinch, E., Dhesi, A., Dernedde, C., Lawrence, M., Simper, H., Noble, M., Dalton, G., Stevens, L., Berry, P., Hand, C., Oliver, R., Jones, H., Sampson, P., Taylor, N., Grogono, R., Dalrymple, J., Martin, A., Thurston, S., Elsby, K., Vallis, M., Morrison, G., Lang, C., Watson, A., Thomson, A., Dougall, H., La Hay, B., Compson, L., McCracken, A., Calder, J., Weber, F., Richmond, D., Brownlie, R., Brown, G., MacCowan, H., Heap, A., Perry, M., Holden, L. A., Scott, G., Haldane, N., Hood, S., Cullen, I., Bell, J., McNaught, P., Sharif, M., Dunn, J., Hay, D., Ross, S., Shaw, R., Hay, L., Langridge, S., Burns, R., Crawford, L., Kennedy, A., Logan, D., McAlavey, P., Brown, M., Costello, P., McLaren, G., Potter, A., McPherson, J., Drijfhout, M., Finlayson, J., Troup, D., Woodall, A., Pearce, J., Williams, S., Parkar, W., Yusuf, A., Benett, I., Bishop, P., Thomas, H., Caldwell, I., Ormiston, P., Kwok, S., Kanumilli, N., Saul, P., Milligan, H., Wilkinson, I., Vance, A., Paul, N., Paul, C., Shaikh, I., Ellis, R., Vites, N., Steeds, R., Goodwin, D., Aftab, A., Banham, S., Chauhan, N., Grocutt, M. S., Gupte, A., Jordan, R., Jheeta, B. S., Ladha, K., Nazir, M., Pal, R., Patel, R. P., McManus, R., Singal, A., Saunders, P., Syed, A. B., Bahal, A., Dau, H., Walker, D. M., McNeilly, R., Bolidai, A., MacCarthy, N., Lawton, D., Vardhani, M., Sengupta, G., Kinloch, D., Howie, F., Serrano-Garcia, A., Paget, S. E., Till, R., Seal, P., Morrell, J., Maxwell, T., Singh, G., Warden, D., Elias, R., Dixon, C., Pandey, R. K., Challenor, V., Davies, S., Gibbs, M., Gillet, A., Goldie, C., Jarvis, I., Johnson, P., Malden, M., Moore, J., Morton, C., Nehrig, K., Sheringham, P., Wilson, G., Halcox, J., O'Connor, I., Ling, K., Edwards, D., Charles, H., Weatherup, A., Davies, E., Watkins, N., Morgan, D., Davies, R., Lindsay, A., Beacock, D., Balai, R., Kirmond, P., Brindle, P., Bundy, C., Cahill, T., Dayani, A., Eavis, P., Mohr, S., Hayne, S., Krasucki, C., Micheals, M., Orpen, I., Parker, I., Sewell, R., Sharp, D., Smith, A., Stevens, A., Upton, J., Victory, J., Wernham, C., Davis, R., Mays, C., Andrews, M., Takhar, J., Travill, C., Choudhury, P., Matta, W., Ihonor, A., O'Dong, C., Rahman, S., Singer, P., Gillam, S., Bath, P. S., Razzaq, N., O'Toole, O., Rowe, P., Williams, H., Allcock, A., Tucker, A., Sprott, V., Kyd, K., Cunliffe, G., Arden, C., Bateman, A., Kassianos, G., Sinclair, D., Turner, C., Jagathesan, R., Sattar, F., Ashford, A., Chukwu, A., Taylor, H., Pradhan, R., Rundell, T., Howlett, R., Bietzk, R., Myint, M., Partington, M., O'Reilly, F., Baverstock, M., Dixon, S., Tennekoon, M., Brand, N., Haimes, P., Keller, P., Whetstone, S., Kovyrshyna, O., Rogozhyna, V., Kiver, T., Vasylenko, V., Kucheryava, L., Salimova, S., Alekseenko, V., Gukov, O., Myhailiv, I., Kardashevskaya, L., Prikolota, O., Bashkirtcev, O., Andreev, E., Tkachenko, L., Mospan, M., Batushkin, V., Safonova, L., Ogorodnichuk, A., Pustovit, S., Romanov, S., Burlakova, L., Voloshko, Y., Lafarenko, V., Vlasuk, Z., Leshchuk, O., Chushak, S., Koval, V., Stasuk, O., Pogrebna, O., Kornienko, S., Tikhonova, S., Fesenko, T., Kuzmina, T., Ushakov, O., Vechtomova, N., Potapska, L., Illushechkin, I., Kryvenkova, E., Lysunets, O., Tsygankov, O., Bardachenko, L., Voloshyna, L., Ginzburg, V., Franskyavichene, L., Korotich, T., Vyshnevaya, N., Bilous, N., Kulinich, S., Kulik, V., Sadykova, I., Berezhna, T., Molotyagina, S., Pham, M. H., Pham, H. T., Khong, N. H., K. B., Do, T. B., Le, P. A., Do, T. C., Do, Nguyen, N. Q., Q. H., Do, K. C., Vu, Pham, N. H., Pham, T. H. T., M. C., Ta, Phan, D. P., Nguyen, T. T. H., Pham, T. T. N., T. L., To, V. T., Le, Dang, L., Bui, L., Pham, T. T. H., Phan, H. H., Bui, T. T. H., Tuong, T. V. A., Nguyen, T. P., Nguyen, T. H., Nguyen, B. K., D. B., Vu, Pham, N. S., T. Q., Do, Pham, T. S., Dang, V. D., D. T., Le, V. C., Do, Nguyen, T. K. L., Luong, H. D., Luu, T. Q., Pham, N. V., Huynh, T. K., N. T. H., Tu, Ngo, K. A., Nguyen, T. T. C., Ong, T. T. L., Doan, V. B., Kim, T. B., T. N., Vo, Tran, T. T. T., Nguyen, T. A., Tran, V. D., Nguyen, A. K., Tran, A. C., Ngo, M. H., N. H., Vu, I. T., Ly, Tran, N. P. H., Tran, L. U. P., Nguyen, T. N., Tran, T. H., Truong, P. H., Mai, T. L., Hoang, V. S., Bui, C. M. A., Dang, V. P., Truong, Q. B., M. P., Vo, Nguyen, V. T., Chau, N. H., T. T. H., Ta, Dinh, H. N., Tran, H., Nguyen, H. K. N., Chung, A., Chung, E., Martina-Hooi, B., Angela, R., Ramoutar, P., Fillet, R., Tilluckdharry, R., Dookie, T., Foster, E., Hart, C., Omardeen, F., Ramphall, S., Lalla, C., Cheng, J., Elliott, V., Falconer, H., Hurlock-Clarke, L., Ishmael, R., Lalljie, G., Lee, K., Liqui-Lung, A., Massay, R., Mohammed, H., Brown, C., Daniel, R., Didier, M., Salas, Z., CHU Trousseau [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), University of Glasgow, Maria Cecilia Hospital [Cotignola], Royal Brompton Hospital, Montreal Heart Institute Coordinating Centre (MHICC), Université de Montréal (UdeM), Medical University of Silesia (SUM), Université Paris Diderot - Paris 7 (UPD7), Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Dorogoichenko, Aleksandra, Laucevičius, Aleksandras, Jurgaitienė, Rūta, Šlapikas, Rimvydas, Barauskienė, Gražina, Jankauskienė, Edita, Revienė, Sigita, Vaišvila, Tautvydas, Zaronskienė, Danutė, Šlapikienė, Ona Birutė, Kupstytė, Nora, Rinkūnienė, Egidija, Steponėnienė, Rima Vitalija, Kojelienė, Jūratė, Badarienė, Jolita, Dženkevičiūtė, Vilma, Sadauskienė, Eglė, Butkuvienė, Irena, Stankevičius, R., Paliulionienė, R., Snikytė, R., Mažutavičius, R., and CLARIFY Investigators
- Subjects
Male ,Genetics and Molecular Biology (all) ,Heart disease ,medicine.medical_treatment ,atrial fibrillation ,coronary ,anticoagulants ,patients ,atrial flutter ,lcsh:Medicine ,Coronary Artery Disease ,Practice Patterns ,030204 cardiovascular system & hematology ,Chest pain ,Biochemistry ,[SHS]Humanities and Social Sciences ,Cohort Studies ,Coronary artery disease ,Angina ,0302 clinical medicine ,Aged ,Anticoagulants ,Atrial Fibrillation ,Drug Therapy, Combination ,Female ,Guideline Adherence ,Humans ,Outpatients ,Platelet Aggregation Inhibitors ,Practice Patterns, Physicians' ,Registries ,Practice Patterns, Physicians'/statistics & numerical data ,030212 general & internal medicine ,Myocardial infarction ,lcsh:Science ,Stroke ,Anticoagulants/administration & dosage ,Multidisciplinary ,Medicine (all) ,Atrial fibrillation ,Guideline Adherence/statistics & numerical data ,3. Good health ,Combination ,Cardiology ,[SHS] Humanities and Social Sciences ,medicine.symptom ,Research Article ,medicine.medical_specialty ,Coronary Artery Disease/drug therapy ,Agricultural and Biological Sciences (all) ,Biochemistry, Genetics and Molecular Biology (all) ,NO ,03 medical and health sciences ,Drug Therapy ,Internal medicine ,medicine ,Platelet Aggregation Inhibitors/administration & dosage ,Physicians' ,Atrial Fibrillation/drug therapy ,business.industry ,lcsh:R ,Percutaneous coronary intervention ,Outpatients/statistics & numerical data ,medicine.disease ,lcsh:Q ,Human medicine ,business - Abstract
BACKGROUND: Few data are available regarding the use of antithrombotic strategies in coronary artery disease patients with atrial fibrillation (AF) in everyday practice. We sought to describe the prevalence of AF and its antithrombotic management in a contemporary population of patients with stable coronary artery disease.METHODS AND FINDINGS: CLARIFY is an international, prospective, longitudinal registry of outpatients with stable coronary artery disease, defined as prior (≥12 months) myocardial infarction, revascularization procedure, coronary stenosis >50%, or chest pain associated with evidence of myocardial ischemia. Overall, 33,428 patients were screened, of whom 32,954 had data available for analysis at baseline; of these 2,229 (6.7%) had a history of AF. Median (interquartile range) CHA2DS2-VASc score was 4 (3, 5). Oral anticoagulation alone was used in 25.7%, antiplatelet therapy alone in 52.8% (single 41.8%, dual 11.0%), and both in 21.5%. OAC use was independently associated with permanent AF (pCONCLUSIONS: In this contemporary cohort of patients with stable coronary artery disease and AF, most of whom are theoretical candidates for anticoagulation, oral anticoagulants were used in only 47.2%. Half of the patients received antiplatelet therapy alone and one-fifth received both antiplatelets and oral anticoagulants. Efforts are needed to improve adherence to guidelines in these patients.TRIAL REGISTRATION: ISRCTN registry of clinical trials: ISRCTN43070564.
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- 2015
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39. Role of new biomarkers for the diagnosis of nephropathy associated with diabetes type 2
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Żyłka, A., Agnieszka Gala-Błądzińska, Rybak, K., Dumnicka, P., Drożdż, R., and Kuśnierz-Cabala, B.
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diabetes mellitus type 2 ,biomarkers ,diabetic kidney disease - Published
- 2015
40. Positionspapier Telemonitoring: Von den Nukleusmitgliedern der AG33 Telemonitoring in der DGK und assoziierten Mitgliedern.
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Helms, T. M., Stockburger, M., Köhler, F., Leonhardt, V., Müller, A., Rybak, K., Sack, S., Schwab, J. O., Zugck, C., Zippel-Schultz, B., and Perings, C. A.
- Abstract
Copyright of Herzschrittmachertherapie und Elektrophysiologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2019
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41. Befundkonstellation und abgeleitete Behandlungsinterventionen bei telemedizinisch überwachten Patienten mit Herzinsuffizienz, Herzrhythmusstörungen oder erhöhtem Risiko für den plötzlichen Herztod: Empfehlungen der Arbeitsgruppe 33 Telemonitoring der Deutschen Gesellschaft für Kardiologie, Herz- und Kreislaufforschung e. V
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Helms, T. M., Stockburger, M., Schwab, J. O., Hindricks, G., Köhler, F., Leonhardt, V., Müller, A., Rybak, K., Sack, S., Zugck, C., Zippel-Schultz, B., and Perings, C. A.
- Abstract
Copyright of Herzschrittmachertherapie und Elektrophysiologie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2019
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42. Dissecting the role of histidine kinase and Hog1 mitogen-activated protein kinase signalling in stress tolerance and pathogenicity of Parastagonospora nodorum on wheat.
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John, E., Lopez-Ruiz, F., Rybak, K., Mousley, C., Oliver, R., Tan, Kar-Chun, John, E., Lopez-Ruiz, F., Rybak, K., Mousley, C., Oliver, R., and Tan, Kar-Chun
- Abstract
The HOG1 mitogen-activated protein kinase (MAPK) pathway is activated through two-component histidine kinase (HK) signalling. This pathway was first characterized in the budding yeast Saccharomyces cerevisiae as a regulator of osmotolerance. The fungus Parastagonospora nodorum is the causal agent of septoria nodorum blotch of wheat. This pathogen uses host-specific effectors in tandem with general pathogenicity mechanisms to carry out its infection process. Genes showing strong sequence homology to S. cerevisiae HOG1 signalling pathway genes have been identified in the genome of P. nodorum. In this study, we examined the role of the pathway in the virulence of P. nodorum on wheat by disrupting putative pathway component genes: HOG1 (SNOG_13296) MAPK and NIK1 (SNOG_11631) hybrid HK. Mutants deleted in NIK1 and HOG1 were insensitive to dicarboximide and phenylpyrrole fungicides, but not a fungicide that targets ergosterol biosynthesis. Furthermore, both Δnik1 and Δhog1 mutants showed increased sensitivity to hyperosmotic stress. However, HOG1, but not NIK1, is required for tolerance to elevated temperatures. HOG1 deletion conferred increased tolerance to 6-methoxy-2-benzoxazolinone, a cereal phytoalexin. This suggests that the HOG1 signalling pathway is not exclusively associated with NIK1. Both Δnik1 and Δhog1 mutants retained the ability to infect and cause necrotic lesions on wheat. However, we observed that the Δhog1 mutation resulted in reduced production of pycnidia, asexual fruiting bodies that facilitate spore dispersal during late infection. Our study demonstrated the overlapping and distinct roles of a HOG1 MAPK and two-component HK signalling in P. nodorum growth and pathogenicity.
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- 2016
43. Cell cycle-regulated PLEIADE/AtMAP65-3 links membrane and microtubule dynamics during plant cytokinesis
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Steiner, A, Rybak, K, Altmann, M, McFarlane, HE, Klaeger, S, Ngoc, N, Facher, E, Ivakov, A, Wanner, G, Kuster, B, Persson, S, Braun, P, Hauser, M-T, Assaad, FF, Steiner, A, Rybak, K, Altmann, M, McFarlane, HE, Klaeger, S, Ngoc, N, Facher, E, Ivakov, A, Wanner, G, Kuster, B, Persson, S, Braun, P, Hauser, M-T, and Assaad, FF
- Abstract
Cytokinesis, the partitioning of the cytoplasm following nuclear division, requires extensive coordination between cell cycle cues, membrane trafficking and microtubule dynamics. Plant cytokinesis occurs within a transient membrane compartment known as the cell plate, to which vesicles are delivered by a plant-specific microtubule array, the phragmoplast. While membrane proteins required for cytokinesis are known, how these are coordinated with microtubule dynamics and regulated by cell cycle cues remains unclear. Here, we document physical and genetic interactions between Transport Protein Particle II (TRAPPII) tethering factors and microtubule-associated proteins of the PLEIADE/AtMAP65 family. These interactions do not specifically affect the recruitment of either TRAPPII or MAP65 proteins to the cell plate or midzone. Rather, and based on single versus double mutant phenotypes, it appears that they are required to coordinate cytokinesis with the nuclear division cycle. As MAP65 family members are known to be targets of cell cycle-regulated kinases, our results provide a conceptual framework for how membrane and microtubule dynamics may be coordinated with each other and with the nuclear cycle during plant cytokinesis.
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- 2016
44. Differential effector gene expression underpins epistasis in a plant fungal disease.
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Phan, Huyen, Rybak, K., Furuki, Eiko, Breen, S., Solomon, P., Oliver, Richard, Tan, Kar-Chun, Phan, Huyen, Rybak, K., Furuki, Eiko, Breen, S., Solomon, P., Oliver, Richard, and Tan, Kar-Chun
- Abstract
Fungal effector-host sensitivity gene interactions play a key role in determining the outcome of septoria nodorum blotch disease (SNB) caused by Parastagonospora nodorum on wheat. The pathosystem is complex and mediated by interaction of multiple fungal necrotrophic effector-host sensitivity gene systems. Three effector-sensitivity gene systems are well characterised in this pathosystem; SnToxA-Tsn1, SnTox1-Snn1 and SnTox3-Snn3. We tested a wheat mapping population that segregated for Snn1 and Snn3 with SN15, an aggressive P. nodorum isolate that produces SnToxA, SnTox1 and SnTox3, to study the inheritance of sensitivity to SnTox1 and SnTox3 and disease susceptibility. Interval quantitative trait locus (QTL) mapping showed that the SnTox1-Snn1 interaction was paramount in SNB development on both seedlings and adult plants. No effect of the SnTox3-Snn3 interaction was observed under SN15 infection. The SnTox3-Snn3 interaction was however, detected in a strain of SN15 in which SnTox1 had been deleted (tox1-6). Gene expression analysis indicates increased SnTox3 expression in tox1-6 compared to SN15. This indicates that the failure to detect the SnTox3-Snn3 interaction in SN15 is due - at last in part - to suppressed expression of SnTox3 mediated by SnTox1 Furthermore, infection of the mapping population with a strain deleted in SnToxA, SnTox1 and SnTox3 (toxa13) unmasked a significant SNB QTL on 2DS where the SnTox2 effector sensitivity gene, Snn2, is located.This QTL was not observed in SN15 and tox1–6 infections and thus suggesting that SnToxA and/or SnTox3 were epistatic. Additional QTLs responding to SNB and effectors sensitivity were detected on 2AS1 and 3AL.
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- 2016
45. Telemonitoring in der Devicetherapie: gelebte Wirklichkeit?
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Rybak, K., additional
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- 2016
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46. Ist ein Kardiologe immer im Dienst?!
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Schneider, H., additional, Bosch, R., additional, Ebermann, T., additional, Hansen, C., additional, Klingenheben, T., additional, Rybak, K., additional, and Smetak, N., additional
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- 2016
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47. Functional redundancy of necrotrophic effectors – consequences for exploitation for breeding
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Tan, Kar-Chun, Phan, Huyen Phan, Rybak, K., John, E., Chooi, Y., Solomon, P., Oliver, Richard, Tan, Kar-Chun, Phan, Huyen Phan, Rybak, K., John, E., Chooi, Y., Solomon, P., and Oliver, Richard
- Abstract
Necrotrophic diseases of wheat cause major losses in most wheat growing areas of world. Tan spot (caused by Pyrenophora tritici-repentis) and septoria nodorum blotch (SNB; Parastagonospora nodorum) have been shown to reduce yields by 10–20% across entire agri-ecological zones despite the application of fungicides and a heavy focus over the last 30 years on resistance breeding. Efforts by breeders to improve the resistance of cultivars has been compromised by the universal finding that resistance was quantitative and governed by multiple quantitative trait loci (QTL). Most QTL had a limited effect that was hard to measure precisely and varied significantly from site to site and season to season. The discovery of necrotrophic effectors has given breeding for disease resistance new methods and tools. In the case of tan spot in West Australia, a single effector, PtrToxA and its recogniser gene Tsn1, has a dominating impact in disease resistance. The delivery of ToxA to breeders has had a major impact on cultivar choice and breeding strategies. For P. nodorum, three effectors – SnToxA, SnTox1, and SnTox3 – have been well characterized. Unlike tan spot, no one effector has a dominating role. Genetic analysis of various mapping populations and pathogen isolates has shown that different effectors have varying impact and that epistatic interactions also occur. As a result of these factors the deployment of these effectors for SNB resistance breeding is more complex. We have deleted the three effectors in a strain of P. nodorum and measured effector activity and disease potential of the triple knockout mutant. The culture filtrate causes necrosis in several cultivars and the strain causes disease, albeit the overall levels are less than in the wild type. Modeling of the field disease resistance scores of cultivars from their reactions to the microbially expressed effectors SnToxA, SnTox1, and SnTox3 is significantly improved by including the response to the triple knockout mu
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- 2015
48. Palpitationen und Vorhofflimmern
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Wachter, R., additional and Rybak, K., additional
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- 2015
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49. Blood metabolic response to a long-term wheelchair rugby training
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Sadowska-Krępa, E, primary, Zwierzchowska, A, additional, Głowacz, M, additional, Borowiec-Rybak, K, additional, and Kłapcińska, B, additional
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- 2015
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50. Quantum Time in Nuclear Physics
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Góźdź, A., primary, Rybak, K., additional, Pędrak, A., additional, and Góźdź, M., additional
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- 2015
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