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Your search keyword '"Rittweger, Joern"' showing total 393 results
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393 results on '"Rittweger, Joern"'

22. Lessons for Flying Astronauts with Disabilities Drawn from Experience in Aviation.

Author

Miller-Smith, Mike J., Tucker, Neil, Anderton, Ryan, Caplin, Nicol, Harridge, Stephen D. R., Hodkinson, Peter, Narici, Marco Vincenzo, Pollock, Ross D., Possnig, Carmen, Rittweger, Joern, Smith, Thomas G., and Di Giulio, Irene

Subjects
PEOPLE with disabilities, ASTRONAUTS, IMPLICIT bias, DISABILITIES, SPACE flight, SPACE exploration
Abstract

INTRODUCTION: A ccessible spaceflight may seem a distant concept. As part of a diverse European Space Agency funded Topical Team, we are working on the physiological feasibility of space missions being undertaken by people with physical disabilities. Here, the first activity of this team is presented in the form of key lessons learned from aviation to inform new work on space missions. DISCUSSION: The first lesson is agreeing on realistic expectations about impairments, their severity, and the possibility of flying independently. This is important in terms of astronaut recruitment and societal expectations. The second lesson relates to training and adjustments for people with disabilities. Flexibility is important while maintaining safety for everyone involved. The third lesson is about managing unconscious bias from the different stakeholders. We conclude by arguing that engagement with people from different backgrounds is essential for the success of the first space mission with people with physical disabilities. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Nitrosative Stress in Astronaut Skeletal Muscle in Spaceflight

Author

Blottner, Dieter, primary, Moriggi, Manuela, additional, Trautmann, Gabor, additional, Furlan, Sandra, additional, Block, Katharina, additional, Gutsmann, Martina, additional, Torretta, Enrica, additional, Barbacini, Pietro, additional, Capitanio, Daniele, additional, Rittweger, Joern, additional, Limper, Ulrich, additional, Volpe, Pompeo, additional, Gelfi, Cecilia, additional, and Salanova, Michele, additional

Published
2024
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24. Towards human exploration of space: the THESEUS review series on muscle and bone research priorities

Author

Lang, Thomas, Van Loon, Jack JWA, Bloomfield, Susan, Vico, Laurence, Chopard, Angele, Rittweger, Joern, Kyparos, Antonios, Blottner, Dieter, Vuori, Ilkka, Gerzer, Rupert, and Cavanagh, Peter R

Subjects
Engineering, Health Sciences, Biomedical Engineering, Physical Injury - Accidents and Adverse Effects, Osteoporosis, Aging, Musculoskeletal
Abstract

Without effective countermeasures, the musculoskeletal system is altered by the microgravity environment of long-duration spaceflight, resulting in atrophy of bone and muscle tissue, as well as in deficits in the function of cartilage, tendons, and vertebral disks. While inflight countermeasures implemented on the International Space Station have evidenced reduction of bone and muscle loss on low-Earth orbit missions of several months in length, important knowledge gaps must be addressed in order to develop effective strategies for managing human musculoskeletal health on exploration class missions well beyond Earth orbit. Analog environments, such as bed rest and/or isolation environments, may be employed in conjunction with large sample sizes to understand sex differences in countermeasure effectiveness, as well as interaction of exercise with pharmacologic, nutritional, immune system, sleep and psychological countermeasures. Studies of musculoskeletal biomechanics, involving both human subject and computer simulation studies, are essential to developing strategies to avoid bone fractures or other injuries to connective tissue during exercise and extravehicular activities. Animal models may be employed to understand effects of the space environment that cannot be modeled using human analog studies. These include studies of radiation effects on bone and muscle, unraveling the effects of genetics on bone and muscle loss, and characterizing the process of fracture healing in the mechanically unloaded and immuno-compromised spaceflight environment. In addition to setting the stage for evidence-based management of musculoskeletal health in long-duration space missions, the body of knowledge acquired in the process of addressing this array of scientific problems will lend insight into the understanding of terrestrial health conditions such as age-related osteoporosis and sarcopenia.

Published
2017

27. Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity

Author

Gnad, Thorsten, Navarro, Gemma, Lahesmaa, Minna, Reverte-Salisa, Laia, Copperi, Francesca, Cordomi, Arnau, Naumann, Jennifer, Hochhäuser, Aileen, Haufs-Brusberg, Saskia, Wenzel, Daniela, Suhr, Frank, Jespersen, Naja Zenius, Scheele, Camilla, Tsvilovskyy, Volodymyr, Brinkmann, Christian, Rittweger, Joern, Dani, Christian, Kranz, Mathias, Deuther-Conrad, Winnie, Eltzschig, Holger K., Niemi, Tarja, Taittonen, Markku, Brust, Peter, Nuutila, Pirjo, Pardo, Leonardo, Fleischmann, Bernd K., Blüher, Matthias, Franco, Rafael, Bloch, Wilhelm, Virtanen, Kirsi A., and Pfeifer, Alexander

Published
2020
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44. A Computer Game Based Motivation System for Human Physiology Studies

Author

Mathew, Tintu, Zange, Jochen, Rittweger, Joern, Herpers, Rainer, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Ma, Minhua, editor, Oliveira, Manuel Fradinho, editor, Hauge, Jannicke Baalsrud, editor, Duin, Heiko, editor, and Thoben, Klaus-Dieter, editor

Published
2012
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48. Phyysiological Targets of Artificial Gravity: Adaptive Processes in Bone

Author

Rittweger, Jörn, Wertz, James R., editor, Doré, Roland, editor, Larson, Wiley J., editor, Logsdon, Tom, editor, Markley, Landis, editor, Melton, Robert G., editor, Ninomiya, Keiken, editor, Pocha, Jehangir J., editor, Shuster, Malcolm D., editor, Squibb, Gael, editor, Sweeting, Martin, editor, Clément, Gilles, editor, and Bukley, Angie, editor

Published
2007
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50. Age-Related Declines in Lower Limb Muscle Function are Similar in Power and Endurance Athletes of Both Sexes: A Longitudinal Study of Master Athletes

Author

Ireland, Alex, Mittag, Uwe, Degens, Hans, Felsenberg, Dieter, Heinonen, Ari, Koltai, Erika, Korhonen, Marko T., McPhee, Jamie S., Mekjavic, Igor, Pisot, Rado, Rawer, Rainer, Radak, Zsolt, Simunic, Bostjan, Suominen, Harri, Rittweger, Joern, Ireland, Alex, Mittag, Uwe, Degens, Hans, Felsenberg, Dieter, Heinonen, Ari, Koltai, Erika, Korhonen, Marko T., McPhee, Jamie S., Mekjavic, Igor, Pisot, Rado, Rawer, Rainer, Radak, Zsolt, Simunic, Bostjan, Suominen, Harri, and Rittweger, Joern

Abstract

The age-related decline in muscle function, particularly muscle power, is associated with increased risk of important clinical outcomes. Physical activity is an important determinant of muscle function, and different types of physical activity e.g. power-based versus endurance-based exercise appear to have differential effects on muscle power. Cross-sectional studies suggest that participation in power-based exercise is associated with greater muscle power across adulthood but this has not been investigated longitudinally. We recruited eighty-nine male and female power and endurance master athletes (sprint and distance runners respectively, baseline age 35-90y). Using jumping mechanography, we measured lower limb muscle function during a vertical jump including at least two testing sessions longitudinally over 4.5 +/- 2.4y. We examined effects of time, discipline (power/endurance) and sex in addition to two- and three-way interactions using linear mixed-effects models. Peak relative power, relative force and jump height, but not Esslingen Fitness Index (indicating peak power relative to sex and age-matched reference data) declined with time. Peak power, force, height and EFI were greater in power than endurance athletes. There were no sex, discipline or sex*discipline interactions with time for any variable, suggesting that changes were similar over time for athletes of both sexes and disciplines. Advantages in lower limb muscle function in power athletes were maintained with time, in line with previous cross-sectional studies. These results suggest that improvements in lower limb function in less active older individuals following power-based training persist with continued adherence, although this requires further investigation in interventional studies.

Published
2022

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