1. COPD overlap conditions: Clinical and therapeutic implications.
- Author
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Jarrah A, Awad MT, Cramer-Bour C, and Soubani AO
- Subjects
- Humans, Sleep Apnea, Obstructive therapy, Sleep Apnea, Obstructive diagnosis, Sleep Apnea, Obstructive complications, Bronchiectasis therapy, Bronchiectasis diagnosis, Bronchiectasis physiopathology, Bronchiectasis etiology, Asthma therapy, Asthma diagnosis, Asthma physiopathology, Asthma complications, Pulmonary Fibrosis therapy, Pulmonary Fibrosis diagnosis, Pulmonary Fibrosis physiopathology, Pulmonary Fibrosis complications, Pulmonary Emphysema therapy, Pulmonary Emphysema diagnosis, Pulmonary Emphysema physiopathology, Pulmonary Disease, Chronic Obstructive therapy, Pulmonary Disease, Chronic Obstructive diagnosis, Pulmonary Disease, Chronic Obstructive complications, Pulmonary Disease, Chronic Obstructive physiopathology
- Abstract
Chronic Obstructive Pulmonary Disease (COPD) is a complex pulmonary condition characterized by chronic airflow limitation. Within the spectrum of COPD, distinct overlap conditions exist, including Asthma-COPD Overlap (ACO), COPD-Obstructive Sleep Apnea (COPD-OSA), Combined Pulmonary Fibrosis and Emphysema (CPFE), and Bronchiectasis-COPD Overlap (BCO). This review provides a comprehensive overview of the clinical and therapeutic implications of these conditions, highlighting the differences in complications compared with COPD alone in addition to the diagnostic challenges of identifying these conditions. Therapeutically tailored approaches are necessary for COPD overlap conditions considering the unique complications that may arise. Optimal pharmacological management, disease-specific interventions, and comprehensive patient-centered care are crucial components of treatment strategies. This review provides insights for healthcare professionals by enhancing their understanding and management of these conditions. This emphasizes the importance of accurate diagnosis and individualized treatment plans, considering the specific complications associated with each COPD overlap condition., Competing Interests: Declaration of competing interest No conflicts of interest or relationship with the industry to disclose by any of the authors. No funding or financial interests., (Copyright © 2024 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.) more...
- Published
- 2024
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