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322 results on '"Ohmori, Koji"'

1. Intracoronary administration of nicorandil during primary percutaneous coronary intervention: Impact on restoration of regional myocardial perfusion in reperfused myocardium during the subacute phase of myocardial infarction

Author

Takabatake, Wataru, Noma, Takahisa, Iwado, Yasuyoshi, Ishikawa, Shohei, Tobiume, Atsushi, Hasui, Yusuke, Matsunaga, Keiji, Mantani, Kaoru, Konishi, Kumi, Kawakami, Ryo, Ishihara, Naoko, Ishihara, Yasuhiro, Ishizawa, Makoto, Ishikawa, Kaori, Murakami, Kazushi, Ohmori, Koji, Nishiyama, Yoshihiro, and Kohno, Masakazu

Published
2015
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4. Automatic Mobile Robot Control and Indication Method Using Augmented Reality Technology

Author

Ohmori, Koji, Sakamoto, Kunio, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Yang, Hyun Seung, editor, Malaka, Rainer, editor, Hoshino, Junichi, editor, and Han, Jung Hyun, editor

Published
2010
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12. Involvement of endogenous nitric oxide in angiotensin II-induced activation of vascular mitogen-activated protein kinases

Author

Zhang, Guo-Xing, Nagai, Yukiko, Nakagawa, Toshitaka, Miyanaka, Hiroshi, Fujisawa, Yoshihide, Nishiyama, Akira, Izuishi, Kunihiko, Ohmori, Koji, and Kimura, Shoji

Subjects
Angiotensin -- Properties, Protein kinases -- Properties, Oxidative stress -- Evaluation, Cell physiology -- Research, Nitric oxide -- Influence, Nitric oxide -- Health aspects, Biological sciences
Abstract

Angiotensin II (ANG II) is a powerful activator of mitogen-activated protein (MAP) kinase cascades in cardiovascular tissues through a redox-sensitive mechanism. Nitric oxide (NO) is considered to antagonize the vasoconstrictire and proarteriosclerotic actions of ANG II. However, the role of endogenous NO in ANG II-induced redox-sensitive signal transduction is not yet clear. In this study using catheterized, conscious rats, we found that acute intravenous administration of [N.sup.G]-nitro-L-arginine methyl ester (L-NAME; 5 mg/kg) enhanced phosphorylation of aortic MAP kinases extracellular signal regulated kinase (ERK) 1/2 and p38, which were suppressed only partially by a superoxide dismutase mimetic (Tempol), whereas ANG II-induced MAP kinase phosphorylation was markedly suppressed by Tempol. FK409, a NO donor, had little effect on vascular MAP kinase phosphorylation. On the other hand, acute exposure to a vasoconstrictor dose of ANG II (200 ng x [kg.sup.-1] x [min.sup.-1] iv) failed to enhance phosphorylation of aortic MAP kinases in the chronically L-NAME-treated rats, whereas the vasoconstrictor effect of ANG II was not affected by L-NAME treatment. Furthermore, three different inhibitors of NO synthase suppressed, in a dose-dependent manner, ANG II-induced MAP kinase phosphorylation in rat vascular smooth muscle cells, which was closely linked to superoxide generation in cells. These results indicate the involvement of endogenous NO synthase in ANG II-induced signaling pathways, leading to activation of MAP kinase, and that NO may have dual effects on the vascular MAP kinase activation associated with redox sensitivity. oxidative stress; [N.sup.G]-nitro-L-arginine methyl ester; extracellular signal-regulated kinase 1/2; p38

Published
2007

46. Increase in tumor suppressor Arf compensates gene dysregulation in in vitro aged adipocytes

Author

Hasan, Arif U., primary, Ohmori, Koji, additional, Hashimoto, Takeshi, additional, Kamitori, Kazuyo, additional, Yamaguchi, Fuminori, additional, Konishi, Kumi, additional, Noma, Takahisa, additional, Igarashi, Junsuke, additional, Yamashita, Tetsuo, additional, Hirano, Katsuya, additional, Tokuda, Masaaki, additional, Minamino, Tetsuo, additional, Nishiyama, Akira, additional, and Kohno, Masakazu, additional

Published
2016
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49. Eicosapentaenoic acid upregulates VEGF-A through both GPR120 and PPARγ mediated pathways in 3T3-L1 adipocytes

Author

Hasan, Arif U., primary, Ohmori, Koji, additional, Konishi, Kumi, additional, Igarashi, Junsuke, additional, Hashimoto, Takeshi, additional, Kamitori, Kazuyo, additional, Yamaguchi, Fuminori, additional, Tsukamoto, Ikuko, additional, Uyama, Toru, additional, Ishihara, Yasuhiro, additional, Noma, Takahisa, additional, Tokuda, Masaaki, additional, and Kohno, Masakazu, additional

Published
2015
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50. The cyclin-dependent kinase inhibitor p21 is essential for the beneficial effects of renal ischemic preconditioning on renal ischemia/reperfusion injury in mice

Author

Nishioka, Satoshi, primary, Nakano, Daisuke, additional, Kitada, Kento, additional, Sofue, Tadashi, additional, Ohsaki, Hiroyuki, additional, Moriwaki, Kumiko, additional, Hara, Taiga, additional, Ohmori, Koji, additional, Kohno, Masakazu, additional, and Nishiyama, Akira, additional

Published
2014
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