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1,075 results on '"Mishra, P. C."'

14. Computational Study of Combustion Process in a Gas Turbine Engine

Author

Muduli, S. K., Mishra, R. K., Mishra, P. C., Cavas-Martínez, Francisco, Editorial Board Member, Chaari, Fakher, Series Editor, di Mare, Francesca, Editorial Board Member, Gherardini, Francesco, Series Editor, Haddar, Mohamed, Editorial Board Member, Ivanov, Vitalii, Series Editor, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Revankar, Shripad, editor, Muduli, Kamalakanta, editor, and Sahu, Debjyoti, editor

Published
2023
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16. KCa channel activation normalizes endothelial function in Type 2 Diabetic resistance arteries by improving intracellular Ca2+ mobilization

Author

Mishra, Ramesh C, Kyle, Barry D, Kendrick, Dylan J, Svystonyuk, Daniyil, Kieser, Teresa M, Fedak, Paul WM, Wulff, Heike, and Braun, Andrew P

Subjects
Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Diabetes, Aetiology, 2.1 Biological and endogenous factors, Acetylcholine, Animals, Arteries, Bradykinin, Calcium, Diabetes Mellitus, Type 2, Endothelium, Vascular, Humans, Intermediate-Conductance Calcium-Activated Potassium Channels, Muscle, Skeletal, Rats, Rats, Wistar, Vasodilation, Calcium-activated K+ channel, Endothelium, Resistance artery, Type 2 Diabetes, Calcium-activated K(+) channel, Clinical Sciences, Endocrinology & Metabolism, Clinical sciences
Abstract

BackgroundEndothelial dysfunction is an early pathogenic event in the progression of cardiovascular disease in patients with Type 2 Diabetes (T2D). Endothelial KCa2.3 and KCa3.1 K+ channels are important regulators of arterial diameter, and we thus hypothesized that SKA-31, a small molecule activator of KCa2.3 and KCa3.1, would positively influence agonist-evoked dilation in myogenically active resistance arteries in T2D.MethodologyArterial pressure myography was utilized to investigate endothelium-dependent vasodilation in isolated cremaster skeletal muscle resistance arteries from 22 to 24 week old T2D Goto-Kakizaki rats, age-matched Wistar controls, and small human intra-thoracic resistance arteries from T2D subjects. Agonist stimulated changes in cytosolic free Ca2+ in acutely isolated, single endothelial cells from Wistar and T2D Goto-Kakizaki cremaster and cerebral arteries were examined using Fura-2 fluorescence imaging.Main findingsEndothelium-dependent vasodilation in response to acetylcholine (ACh) or bradykinin (BK) was significantly impaired in isolated cremaster arteries from T2D Goto-Kakizaki rats compared with Wistar controls, and similar results were observed in human intra-thoracic arteries. In contrast, inhibition of myogenic tone by sodium nitroprusside, a direct smooth muscle relaxant, was unaltered in both rat and human T2D arteries. Treatment with a threshold concentration of SKA-31 (0.3 μM) significantly enhanced vasodilatory responses to ACh and BK in arteries from T2D Goto-Kakizaki rats and human subjects, whereas only modest effects were observed in non-diabetic arteries of both species. Mechanistically, SKA-31 enhancement of evoked dilation was independent of vascular NO synthase and COX activities. Remarkably, SKA-31 treatment improved agonist-stimulated Ca2+ elevation in acutely isolated endothelial cells from T2D Goto-Kakizaki cremaster and cerebral arteries, but not from Wistar control vessels. In contrast, SKA-31 treatment did not affect intracellular Ca2+ release by the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) inhibitor cyclopiazonic acid.ConclusionsCollectively, our data demonstrate that KCa channel modulation can acutely restore endothelium-dependent vasodilatory responses in T2D resistance arteries from rats and humans, which appears to involve improved endothelial Ca2+ mobilization.

Published
2021

18. A Comparative Study of magneto-thermo-elastic wave propagation in a finitely conducting medium under thermoelasticity of type I, II, III

Author

Tiwari, Rakhi and Mishra, J. C.

Subjects
Physics - Classical Physics
Abstract

The present work is concerned with the propagation of electro-magneto-thermoelastic plane waves of assigned frequency in a homogeneous isotropic and finitely conducting elastic medium permeated by a primary uniform external magnetic field. We formulate our problem under the theory of Green and Naghdi of type-III (GN-III) to account for the interactions between the elastic, thermal as well as magnetic fields. A general dispersion relation for coupled waves is deduced to ascertain the nature of waves propagating through the medium. Perturbation technique has been employed to obtain the solution of dispersion relation for small thermo-elastic coupling parameter and identify three different types of waves. We specially analyze the nature of important wave components like, phase velocity, specific loss and penetration depth of all three modes of waves. We attempt to compute these wave components numerically to observe their variations with frequency. The effect of presence of magnetic field is analyzed. Comparative results under theories of type GN-I, II and III have been presented numerically in which we have found that the coupled thermoelastic waves are un-attenuated and nondispersive in case of Green-Naghdi-II model which is completely in contrast with the theories of type-I and type-III. Furthermore, the thermal mode wave is observed to propagate with finite phase velocity in case of GN-II model, whereas the phase velocity of thermal mode wave is found to be an increasing function of frequency in other two cases. We achieve significant variations among the results predicted by all three theories., Comment: 12 pages

Published
2019

19. SKA-31, an activator of Ca2+-activated K+ channels, improves cardiovascular function in aging

Author

John, Cini Mathew, Khaddaj Mallat, Rayan, Mishra, Ramesh C, George, Grace, Singh, Vikrant, Turnbull, Jeannine D, Umeshappa, Channakeshava S, Kendrick, Dylan J, Kim, Taeyeob, Fauzi, Fazlin M, Visser, Frank, Fedak, Paul WM, Wulff, Heike, and Braun, Andrew P

Subjects
Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Prevention, Heart Disease, Aging, Animals, Arterial Pressure, Benzothiazoles, Cells, Cultured, Heart, Male, Potassium Channels, Calcium-Activated, Rats, Sprague-Dawley, Stroke Volume, Vasodilation, Ca2+-activated K+ channels, Arteries, Immune system, Ca(2+)-activated K(+) channels, Pharmacology and Pharmaceutical Sciences, Pharmacology & Pharmacy, Pharmacology and pharmaceutical sciences
Abstract

Aging represents an independent risk factor for the development of cardiovascular disease, and is associated with complex structural and functional alterations in the vasculature, such as endothelial dysfunction. Small- and intermediate-conductance, Ca2+-activated K+ channels (KCa2.3 and KCa3.1, respectively) are prominently expressed in the vascular endothelium, and pharmacological activators of these channels induce robust vasodilation upon acute exposure in isolated arteries and intact animals. However, the effects of prolonged in vivo administration of such compounds are unknown. In our study, we hypothesized that such treatment would ameliorate aging-related cardiovascular deficits. Aged (∼18 months) male Sprague Dawley rats were treated daily with either vehicle or the KCa channel activator SKA-31 (10 mg/kg, intraperitoneal injection; n = 6/group) for 8 weeks, followed by echocardiography, arterial pressure myography, immune cell and plasma cytokine characterization, and tissue histology. Our results show that SKA-31 administration improved endothelium-dependent vasodilation, reduced agonist-induced vascular contractility, and prevented the aging-associated declines in cardiac ejection fraction, stroke volume and fractional shortening, and further improved the expression of endothelial KCa channels and associated cell signalling components to levels similar to those observed in young male rats (∼5 months at end of study). SKA-31 administration did not promote pro-inflammatory changes in either T cell populations or plasma cytokines/chemokines, and we observed no overt tissue histopathology in heart, kidney, aorta, brain, liver and spleen. SKA-31 treatment in young rats had little to no effect on vascular reactivity, select protein expression, tissue histology, plasma cytokines/chemokines or immune cell properties. Collectively, these data demonstrate that administration of the KCa channel activator SKA-31 improved aging-related cardiovascular function, without adversely affecting the immune system or promoting tissue toxicity.

Published
2020

22. Beam-energy and centrality dependence of direct-photon emission from ultra-relativistic heavy-ion collisions

Author

Adare, A., Afanasiev, S., Aidala, C., Ajitanand, N. N., Akiba, Y., Akimoto, R., Al-Bataineh, H., Alexander, J., Alfred, M., Al-Jamel, A., Al-Ta'ani, H., Angerami, A., Aoki, K., Apadula, N., Aphecetche, L., Aramaki, Y., Armendariz, R., Aronson, S. H., Asai, J., Asano, H., Aschenauer, E. C., Atomssa, E. T., Averbeck, R., Awes, T. C., Azmoun, B., Babintsev, V., Bagoly, A., Bai, M., Baksay, G., Baksay, L., Baldisseri, A., Bannier, B., Barish, K. N., Barnes, P. D., Bassalleck, B., Basye, A. T., Bathe, S., Batsouli, S., Baublis, V., Bauer, F., Baumann, C., Baumgart, S., Bazilevsky, A., Belikov, S., Belmont, R., Bennett, R., Berdnikov, A., Berdnikov, Y., Bhom, J. H., Bickley, A. A., Bjorndal, M. T., Blau, D. S., Boer, M., Boissevain, J. G., Bok, J. S., Borel, H., Boyle, K., Brooks, M. L., Brown, D. S., Bryslawskyj, J., Bucher, D., Buesching, H., Bumazhnov, V., Bunce, G., Burward-Hoy, J. M., Butsyk, S., Camacho, C. M., Campbell, S., Roman, V. Canoa, Caringi, A., Castera, P., Chai, J. -S., Chang, B. S., Chang, W. C., Charvet, J. -L., Chen, C. -H., Chernichenko, S., Chi, C. Y., Chiba, J., Chiu, M., Choi, I. J., Choi, J. B., Choi, S., Choudhury, R. K., Christiansen, P., Chujo, T., Chung, P., Churyn, A., Chvala, O., Cianciolo, V., Citron, Z., Cleven, C. R., Cobigo, Y., Cole, B. A., Comets, M. P., del Valle, Z. Conesa, Connors, M., Constantin, P., Csanád, M., Csörgö, T., Dahms, T., Dairaku, S., Danchev, I., Danley, T. W., Das, K., Datta, A., Daugherity, M. S., David, G., Dayananda, M. K., Deaton, M. B., Dehmelt, K., Delagrange, H., Denisov, A., d'Enterria, D., Deshpande, A., Desmond, E. J., Dharmawardane, K. V., Dietzsch, O., Ding, L., Dion, A., Do, J. H., Donadelli, M., D'Orazio, L., Drachenberg, J. L., Drapier, O., Drees, A., Drees, K. A., Dubey, A. K., Durham, J. M., Durum, A., Dutta, D., Dzhordzhadze, V., Edwards, S., Efremenko, Y. V., Egdemir, J., Ellinghaus, F., Emam, W. S., Engelmore, T., Enokizono, A., En'yo, H., Espagnon, B., Esumi, S., Eyser, K. O., Fadem, B., Fan, W., Feege, N., Fields, D. E., Finger, M., Finger, Jr., M., Fleuret, F., Fokin, S. L., Forestier, B., Fraenkel, Z., Frantz, J. E., Franz, A., Frawley, A. D., Fujiwara, K., Fukao, Y., Fung, S. -Y., Fusayasu, T., Gadrat, S., Gainey, K., Gal, C., Gallus, P., Garg, P., Garishvili, A., Garishvili, I., Gastineau, F., Ge, H., Germain, M., Glenn, A., Gong, H., Gong, X., Gonin, M., Gosset, J., Goto, Y., de Cassagnac, R. Granier, Grau, N., Greene, S. V., Grim, G., Perdekamp, M. Grosse, Gunji, T., Guo, L., Gustafsson, H. Å., Hachiya, T., Henni, A. Hadj, Haegemann, C., Haggerty, J. S., Hagiwara, M. N., Hahn, K. I., Hamagaki, H., Hamblen, J., Han, R., Hanks, J., Harada, H., Hartouni, E. P., Haruna, K., Harvey, M., Hasegawa, S., Haseler, T. O. S., Hashimoto, K., Haslum, E., Hasuko, K., Hayano, R., He, X., Heffner, M., Hemmick, T. K., Hester, T., Heuser, J. M., Hiejima, H., Hill, J. C., Hill, K., Hobbs, R., Hodges, A., Hohlmann, M., Hollis, R. S., Holmes, M., Holzmann, W., Homma, K., Hong, B., Horaguchi, T., Hori, Y., Hornback, D., Hotvedt, N., Huang, J., Huang, S., Hur, M. G., Ichihara, T., Ichimiya, R., Iinuma, H., Ikeda, Y., Imai, K., Imrek, J., Inaba, M., Inoue, Y., Iordanova, A., Isenhower, D., Isenhower, L., Ishihara, M., Isobe, T., Issah, M., Isupov, A., Ivanishchev, D., Iwanaga, Y., Jacak, B. V., Javani, M., Ji, Z., Jia, J., Jiang, X., Jin, J., Jinnouchi, O., Johnson, B. M., Jones, T., Joo, K. S., Jouan, D., Jumper, D. S., Kajihara, F., Kametani, S., Kamihara, N., Kamin, J., Kaneta, M., Kaneti, S., Kang, B. H., Kang, J. H., Kang, J. S., Kanou, H., Kapustinsky, J., Karatsu, K., Kasai, M., Kawagishi, T., Kawall, D., Kawashima, M., Kazantsev, A. V., Kelly, S., Kempel, T., Khachatryan, V., Khanzadeev, A., Kijima, K. M., Kikuchi, J., Kim, A., Kim, B. I., Kim, C., Kim, D. H., Kim, D. J., Kim, E., Kim, E. -J., Kim, H. J., Kim, K. -B., Kim, M., Kim, S. H., Kim, Y. -J., Kim, Y. K., Kim, Y. -S., Kincses, D., Kinney, E., Kiriluk, K., Kiss, Á., Kistenev, E., Kiyomichi, A., Klatsky, J., Klay, J., Klein-Boesing, C., Kleinjan, D., Kline, P., Kochenda, L., Kochetkov, V., Komatsu, Y., Komkov, B., Konno, M., Koster, J., Kotchetkov, D., Kotov, D., Kozlov, A., Král, A., Kravitz, A., Krizek, F., Kroon, P. J., Kubart, J., Kunde, G. J., Kurgyis, B., Kurihara, N., Kurita, K., Kurosawa, M., Kweon, M. J., Kwon, Y., Kyle, G. S., Lacey, R., Lai, Y. S., Lajoie, J. G., Layton, D., Lebedev, A., Bornec, Y. Le, Leckey, S., Lee, B., Lee, D. M., Lee, J., Lee, K. B., Lee, K. S., Lee, M. K., Lee, S. H., Lee, S. R., Lee, T., Leitch, M. J., Leite, M. A. L., Leitgab, M., Lenzi, B., Leung, Y. H., Lewis, B., Lewis, N. A., Li, X., Li, X. H., Lichtenwalner, P., Liebing, P., Lim, H., Lim, S. H., Levy, L. A. Linden, Liška, T., Litvinenko, A., Liu, H., Liu, M. X., Lökös, S., Love, B., Lynch, D., Maguire, C. F., Majoros, T., Makdisi, Y. I., Makek, M., Malakhov, A., Malik, M. D., Manion, A., Manko, V. I., Mannel, E., Mao, Y., Mašek, L., Masui, H., Masumoto, S., Matathias, F., McCain, M. C., McCumber, M., McGaughey, P. L., McGlinchey, D., McKinney, C., Means, N., Mendoza, M., Meredith, B., Miake, Y., Mibe, T., Mignerey, A. C., Mihalik, D. E., Mikeš, P., Miki, K., Miller, T. E., Milov, A., Mioduszewski, S., Mishra, D. K., Mishra, G. C., Mishra, M., Mitchell, J. T., Mitrovski, M., Mitsuka, G., Miyachi, Y., Miyasaka, S., Mohanty, A. K., Mohapatra, S., Moon, H. J., Moon, T., Morino, Y., Morreale, A., Morrison, D. P., Morrow, S. I., Moss, J. M., Motschwiller, S., Moukhanova, T. V., Mukhopadhyay, D., Murakami, T., Murata, J., Mwai, A., Nagae, T., Nagamiya, S., Nagashima, K., Nagata, Y., Nagle, J. L., Naglis, M., Nagy, M. I., Nakagawa, I., Nakamiya, Y., Nakamura, K. R., Nakamura, T., Nakano, K., Nam, S., Nattrass, C., Nederlof, A., Newby, J., Nguyen, M., Nihashi, M., Niida, T., Norman, B. E., Nouicer, R., Novák, T., Novitzky, N., Nyanin, A. S., Nystrand, J., Oakley, C., O'Brien, E., Oda, S. X., Ogilvie, C. A., Ohnishi, H., Ojha, I. D., Oka, M., Okada, K., Omiwade, O. O., Onuki, Y., Koop, J. D. Orjuela, Osborn, J. D., Oskarsson, A., Otterlund, I., Ouchida, M., Ozawa, K., Pak, R., Pal, D., Palounek, A. P. T., Pantuev, V., Papavassiliou, V., Park, B. H., Park, I. H., Park, J., Park, S., Park, S. K., Park, W. J., Pate, S. F., Patel, L., Patel, M., Pei, H., Peng, J. -C., Peng, W., Pereira, H., Perepelitsa, D. V., Peresedov, V., Peressounko, D. Yu., PerezLara, C. E., Petti, R., Pinkenburg, C., Pisani, R. P., Proissl, M., Purschke, M. L., Purwar, A. K., Qu, H., Radzevich, P. V., Rak, J., Rakotozafindrabe, A., Ravinovich, I., Read, K. F., Rembeczki, S., Reuter, M., Reygers, K., Reynolds, D., Riabov, V., Riabov, Y., Richardson, E., Richford, D., Rinn, T., Roach, D., Roche, G., Rolnick, S. D., Romana, A., Rosati, M., Rosen, C. A., Rosendahl, S. S. E., Rosnet, P., Rowan, Z., Rukoyatkin, P., Runchey, J., Ružička, P., Rykov, V. L., Ryu, S. S., Sahlmueller, B., Saito, N., Sakaguchi, T., Sakai, S., Sakashita, K., Sakata, H., Sako, H., Samsonov, V., Sano, M., Sano, S., Sarsour, M., Sato, H. D., Sato, S., Sato, T., Sawada, S., Schmoll, B. K., Sedgwick, K., Seele, J., Seidl, R., Semenov, A. Yu., Semenov, V., Sen, A., Seto, R., Sharma, D., Shea, T. K., Shein, I., Shevel, A., Shibata, T. -A., Shigaki, K., Shimomura, M., Shohjoh, T., Shoji, K., Shukla, P., Sickles, A., Silva, C. L., Silvermyr, D., Silvestre, C., Sim, K. S., Singh, B. K., Singh, C. P., Singh, V., Skoby, M. J., Skutnik, S., Slunečka, M., Smith, W. C., Soldatov, A., Soltz, R. A., Sondheim, W. E., Sorensen, S. P., Sourikova, I. V., Staley, F., Stankus, P. W., Stenlund, E., Stepanov, M., Ster, A., Stoll, S. P., Sugitate, T., Suire, C., Sukhanov, A., Sullivan, J. P., Sun, J., Sun, Z., Sziklai, J., Tabaru, T., Takagi, S., Takagui, E. M., Takahara, A., Taketani, A., Tanabe, R., Tanaka, K. H., Tanaka, Y., Taneja, S., Tanida, K., Tannenbaum, M. J., Tarafdar, S., Taranenko, A., Tarján, P., Tennant, E., Themann, H., Thomas, D., Thomas, T. L., Tieulent, R., Todoroki, T., Togawa, M., Toia, A., Tojo, J., Tomášek, L., Tomášek, M., Tomita, Y., Torii, H., Towell, R. S., Tram, V-N., Tserruya, I., Tsuchimoto, Y., Tsuji, T., Tuli, S. K., Tydesjö, H., Tyurin, N., Ueda, Y., Ujvari, B., Vale, C., Valle, H., van Hecke, H. W., Vargyas, M., Vazquez-Zambrano, E., Veicht, A., Velkovska, J., Vértesi, R., Vinogradov, A. A., Virius, M., Vossen, A., Vrba, V., Vznuzdaev, E., Wagner, M., Walker, D., Wang, X. R., Watanabe, D., Watanabe, K., Watanabe, Y., Watanabe, Y. S., Wei, F., Wei, R., Wessels, J., White, S. N., Willis, N., Winter, D., Wolin, S., Wong, C. P., Woody, C. L., Wright, R. M., Wysocki, M., Xia, B., Xie, W., Xu, C., Xu, Q., Yamaguchi, Y. L., Yamaura, K., Yang, R., Yanovich, A., Yasin, Z., Ying, J., Yokkaichi, S., Yoo, J. H., You, Z., Young, G. R., Younus, I., Yu, H., Yushmanov, I. E., Zajc, W. A., Zaudtke, O., Zelenski, A., Zhang, C., Zharko, S., Zhou, S., Zimamyi, J., Zolin, L., and Zou, L.

Subjects
High Energy Physics - Experiment, Nuclear Experiment
Abstract

The PHENIX collaboration presents first measurements of low-momentum ($0.4$1\,GeV/$c$) direct-photon yield $dN_{\gamma}^{\rm dir}/d\eta$ is a smooth function of $dN_{\rm ch}/d\eta$ and can be well described as proportional to $(dN_{\rm ch}/d\eta)^\alpha$ with $\alpha{\approx}1.25$. This scaling behavior holds for a wide range of beam energies at the Relativistic Heavy Ion Collider and the Large Hadron Collider, for centrality selected samples, as well as for different, $A$$+$$A$ collision systems. At a given beam energy the scaling also holds for high $p_T$ ($>5$\,GeV/$c$) but when results from different collision energies are compared, an additional $\sqrt{s_{_{NN}}}$-dependent multiplicative factor is needed to describe the integrated-direct-photon yield., Comment: 673 authors from 82 institutions, 10 pages, 4 figures. v2 is version accepted for publication in Physical Review Letters. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are (or will be) publicly available at http://www.phenix.bnl.gov/papers.html

Published
2018
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28. Intermittent Afterburner Engagement Leading to Single Engine Landing in a Typical Bypass Military Aero Engine

Author

Muduli, Saroj Kumar, Rout, Subrata Kumar, Sahoo, Benudhar, Mishra, P. C., Cavas-Martínez, Francisco, Series Editor, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Haddar, Mohamed, Series Editor, Ivanov, Vitalii, Series Editor, Kwon, Young W., Series Editor, Trojanowska, Justyna, Series Editor, Revankar, Shripad, editor, Sen, Swarnendu, editor, and Sahu, Debjyoti, editor

Published
2021
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30. Alpha1 -adrenergic stimulation selectively enhances endothelium-mediated vasodilation in rat cremaster arteries.

Author

Mishra, Ramesh C, Rahman, Mohammad M, Davis, Michael J, Wulff, Heike, Hill, Michael A, and Braun, Andrew P

Subjects
Muscle, Smooth, Vascular, Endothelium, Vascular, Animals, Rats, Sprague-Dawley, Norepinephrine, Phenylephrine, Acetylcholine, Calcium Channels, L-Type, Potassium Channels, Voltage-Gated, Receptors, Adrenergic, alpha-1, Membrane Potentials, Vasodilation, Male, Nitric Oxide Synthase Type III, Adrenergic alpha-1 Receptor Agonists, eNOS, Endothelium, KCa channel, myogenic tone, vasodilation, α1-Adrenoceptor, eNOS, Calcium Channels, L-Type, Vascular, Muscle, Smooth, Potassium Channels, Voltage-Gated, Rats, Sprague-Dawley, Receptors, Adrenergic, alpha-1, Physiology, Clinical Sciences, Medical Physiology
Abstract

We have systematically investigated how vascular smooth muscle α1 -adrenoceptor activation impacts endothelium-mediated vasodilation in isolated, myogenically active, rat cremaster muscle 1A arteries. Cannulated cremaster arteries were pressurized intraluminally to 70 mmHg to induce myogenic tone, and exposed to vasoactive agents via bath superfusion at 34°C. Smooth muscle membrane potential was measured via sharp microelectrode recordings in pressurized, myogenic arteries. The α1 -adrenergic agonist phenylephrine (25-100 nmol/L) produced further constriction of myogenic arteries, but did not alter the vasorelaxant responses to acetylcholine (0.3 μmol/L), SKA-31 (an activator of endothelial Ca2+ -dependent K+ channels) (3 μmol/L) or sodium nitroprusside (10 μmol/L). Exposure to 0.25-1 μmol/L phenylephrine or 1 μmol/L norepinephrine generated more robust constrictions, and also enhanced the vasodilations evoked by acetylcholine and SKA-31, but not by sodium nitroprusside. In contrast, the thromboxane receptor agonist U46619 (250 nmol/L) dampened responses to all three vasodilators. Phenylephrine exposure depolarized myogenic arteries, and mimicking this effect with 4-aminopyridine (1 mmol/L) was sufficient to augment the SKA-31-evoked vasodilation. Inhibition of L-type Ca2+ channels by 1 μmol/L nifedipine decreased myogenic tone, phenylephrine-induced constriction and prevented α1 -adrenergic enhancement of endothelium-evoked vasodilation; these latter deficits were overcome by exposure to 3 and 10 μmol/L phenylephrine. Mechanistically, augmentation of ACh-evoked dilation by phenylephrine was dampened by eNOS inhibition and abolished by blockade of endothelial KCa channels. Collectively, these data suggest that increasing α1 -adrenoceptor activation beyond a threshold level augments endothelium-evoked vasodilation, likely by triggering transcellular signaling between smooth muscle and the endothelium. Physiologically, this negative feedback process may serve as a "brake" to limit the extent of vasoconstriction in the skeletal microcirculation evoked by the elevated sympathetic tone.

Published
2018

35. Enhanced Photoabsorption from Cobalt Implanted Rutile TiO2 (110) Surfaces

Author

Joshi, Shalik Ram, Padmanabhan, B., Chanda, Anupama, Mishra, Indrani, Malik, V. K., Mishra, N. C., Kanjilal, D., and Varma, Shikha

Subjects
Condensed Matter - Materials Science
Abstract

Present study investigates the photoabsorption properties of single crystal rutile TiO2 (110) surfaces after they have been implanted with low fluence of Cobalt ions. The surfaces, after implantation, demonstrate fabrication of nanostructures and anisotropic nano-ripple patterns. Creation of oxygen vacancies (Ti3+ states) as well as band gap modification for these samples is also observed. Results presented here demonstrate that fabrication of self organized nanostructures and development of oxygen vacancies, upon cobalt implantation, promote the enhancement of photoabsorbance in both UV (2 times) and visible (5 times) regimes. These investigations on nanostructured TiO2 surfaces can be important for photo- catalysis., Comment: 15 pages, 6 Figures

Published
2015

36. Transverse energy production and charged-particle multiplicity at midrapidity in various systems from $\sqrt{s_{NN}}=7.7$ to 200 GeV

Author

Adare, A., Afanasiev, S., Aidala, C., Ajitanand, N. N., Akiba, Y., Akimoto, R., Al-Bataineh, H., Alexander, J., Alfred, M., Al-Jamel, A., Al-Ta'ani, H., Angerami, A., Aoki, K., Apadula, N., Aphecetche, L., Aramaki, Y., Armendariz, R., Aronson, S. H., Asai, J., Asano, H., Aschenauer, E. C., Atomssa, E. T., Averbeck, R., Awes, T. C., Azmoun, B., Babintsev, V., Bai, M., Bai, X., Baksay, G., Baksay, L., Baldisseri, A., Bandara, N. S., Bannier, B., Barish, K. N., Barnes, P. D., Bassalleck, B., Basye, A. T., Bathe, S., Batsouli, S., Baublis, V., Bauer, F., Baumann, C., Baumgart, S., Bazilevsky, A., Beaumier, M., Beckman, S., Belikov, S., Belmont, R., Bennett, R., Berdnikov, A., Berdnikov, Y., Bhom, J. H., Bickley, A. A., Bjorndal, M. T., Black, D., Blau, D. S., Boissevain, J. G., Bok, J. S., Borel, H., Boyle, K., Brooks, M. L., Brown, D. S., Bryslawskyj, J., Bucher, D., Buesching, H., Bumazhnov, V., Bunce, G., Burward-Hoy, J. M., Butsyk, S., Campbell, S., Caringi, A., Castera, P., Chai, J. -S., Chang, B. S., Charvet, J. -L., Chen, C. -H., Chernichenko, S., Chi, C. Y., Chiba, J., Chiu, M., Choi, I. J., Choi, J. B., Choi, S., Choudhury, R. K., Christiansen, P., Chujo, T., Chung, P., Churyn, A., Chvala, O., Cianciolo, V., Citron, Z., Cleven, C. R., Cobigo, Y., Cole, B. A., Comets, M. P., del Valle, Z. Conesa, Connors, M., Constantin, P., Cronin, N., Crossette, N., Csanád, M., Csörgő, T., Dahms, T., Dairaku, S., Danchev, I., Danley, D., Das, K., Datta, A., Daugherity, M. S., David, G., Dayananda, M. K., Deaton, M. B., DeBlasio, K., Dehmelt, K., Delagrange, H., Denisov, A., d'Enterria, D., Deshpande, A., Desmond, E. J., Dharmawardane, K. V., Dietzsch, O., Ding, L., Dion, A., Diss, P. B., Do, J. H., Donadelli, M., D'Orazio, L., Drachenberg, J. L., Drapier, O., Drees, A., Drees, K. A., Dubey, A. K., Durham, J. M., Durum, A., Dutta, D., Dzhordzhadze, V., Edwards, S., Efremenko, Y. V., Egdemir, J., Ellinghaus, F., Emam, W. S., Engelmore, T., Enokizono, A., En'yo, H., Espagnon, B., Esumi, S., Eyser, K. O., Fadem, B., Feege, N., Fields, D. E., Finger, M., Finger Jr., M., Fleuret, F., Fokin, S. L., Forestier, B., Fraenkel, Z., Frantz, J. E., Franz, A., Frawley, A. D., Fujiwara, K., Fukao, Y., Fung, S. -Y., Fusayasu, T., Gadrat, S., Gainey, K., Gal, C., Gallus, P., Garg, P., Garishvili, A., Garishvili, I., Gastineau, F., Ge, H., Germain, M., Giordano, F., Glenn, A., Gong, H., Gong, X., Gonin, M., Gosset, J., Goto, Y., de Cassagnac, R. Granier, Grau, N., Greene, S. V., Grim, G., Perdekamp, M. Grosse, Gu, Y., Gunji, T., Guo, L., Guragain, H., Gustafsson, H. -Å., Hachiya, T., Henni, A. Hadj, Haegemann, C., Haggerty, J. S., Hagiwara, M. N., Hahn, K. I., Hamagaki, H., Hamblen, J., Hamilton, H. F., Han, R., Han, S. Y., Hanks, J., Harada, H., Hartouni, E. P., Haruna, K., Harvey, M., Hasegawa, S., Haseler, T. O. S., Hashimoto, K., Haslum, E., Hasuko, K., Hayano, R., Hayashi, S., He, X., Heffner, M., Hemmick, T. K., Hester, T., Heuser, J. M., Hiejima, H., Hill, J. C., Hobbs, R., Hohlmann, M., Hollis, R. S., Holmes, M., Holzmann, W., Homma, K., Hong, B., Horaguchi, T., Hori, Y., Hornback, D., Hoshino, T., Hotvedt, N., Huang, J., Huang, S., Hur, M. G., Ichihara, T., Ichimiya, R., Iinuma, H., Ikeda, Y., Imai, K., Imazu, Y., Imrek, J., Inaba, M., Inoue, Y., Iordanova, A., Isenhower, D., Isenhower, L., Ishihara, M., Isinhue, A., Isobe, T., Issah, M., Isupov, A., Ivanishchev, D., Iwanaga, Y., Jacak, B. V., Javani, M., Jeon, S. J., Jezghani, M., Jia, J., Jiang, X., Jin, J., Jinnouchi, O., Johnson, B. M., Jones, T., Joo, K. S., Jouan, D., Jumper, D. S., Kajihara, F., Kametani, S., Kamihara, N., Kamin, J., Kanda, S., Kaneta, M., Kaneti, S., Kang, B. H., Kang, J. H., Kang, J. S., Kanou, H., Kapustinsky, J., Karatsu, K., Kasai, M., Kawagishi, T., Kawall, D., Kawashima, M., Kazantsev, A. V., Kelly, S., Kempel, T., Key, J. A., Khachatryan, V., Khandai, P. K., Khanzadeev, A., Kijima, K. M., Kikuchi, J., Kim, A., Kim, B. I., Kim, C., Kim, D. H., Kim, D. J., Kim, E., Kim, E. -J., Kim, G. W., Kim, H. J., Kim, K. -B., Kim, M., Kim, Y. -J., Kim, Y. K., Kim, Y. -S., Kimelman, B., Kinney, E., Kiss, Á., Kistenev, E., Kitamura, R., Kiyomichi, A., Klatsky, J., Klay, J., Klein-Boesing, C., Kleinjan, D., Kline, P., Koblesky, T., Kochenda, L., Kochetkov, V., Kofarago, M., Komatsu, Y., Komkov, B., Konno, M., Koster, J., Kotchetkov, D., Kotov, D., Kozlov, A., Král, A., Kravitz, A., Krizek, F., Kroon, P. J., Kubart, J., Kunde, G. J., Kurihara, N., Kurita, K., Kurosawa, M., Kweon, M. J., Kwon, Y., Kyle, G. S., Lacey, R., Lai, Y. S., Lajoie, J. G., Lebedev, A., Bornec, Y. Le, Leckey, S., Lee, B., Lee, D. M., Lee, G. H., Lee, J., Lee, K. B., Lee, K. S., Lee, M. K., Lee, S, Lee, S. H., Lee, S. R., Lee, T., Leitch, M. J., Leite, M. A. L., Leitgab, M., Lenzi, B., Lewis, B., Li, X., Li, X. H., Lichtenwalner, P., Liebing, P., Lim, H., Lim, S. H., Levy, L. A. Linden, Liška, T., Litvinenko, A., Liu, H., Liu, M. X., Love, B., Lynch, D., Maguire, C. F., Makdisi, Y. I., Makek, M., Malakhov, A., Malik, M. D., Manion, A., Manko, V. I., Mannel, E., Mao, Y., Maruyama, T., Mašek, L., Masui, H., Masumoto, S., Matathias, F., McCain, M. C., McCumber, M., McGaughey, P. L., McGlinchey, D., McKinney, C., Means, N., Meles, A., Mendoza, M., Meredith, B., Miake, Y., Mibe, T., Midori, J., Mignerey, A. C., Mikeš, P., Miki, K., Miller, T. E., Milov, A., Mioduszewski, S., Mishra, D. K., Mishra, G. C., Mishra, M., Mitchell, J. T., Mitrovski, M., Miyachi, Y., Miyasaka, S., Mizuno, S., Mohanty, A. K., Mohapatra, S., Montuenga, P., Moon, H. J., Moon, T., Morino, Y., Morreale, A., Morrison, D. P., Moskowitz, M., Moss, J. M., Motschwiller, S., Moukhanova, T. V., Mukhopadhyay, D., Murakami, T., Murata, J., Mwai, A., Nagae, T., Nagamiya, S., Nagashima, K., Nagata, Y., Nagle, J. L., Naglis, M., Nagy, M. I., Nakagawa, I., Nakagomi, H., Nakamiya, Y., Nakamura, K. R., Nakamura, T., Nakano, K., Nam, S., Nattrass, C., Nederlof, A., Netrakanti, P. K., Newby, J., Nguyen, M., Nihashi, M., Niida, T., Nishimura, S., Norman, B. E., Nouicer, R., Novak, T., Novitzky, N., Nukariya, A., Nyanin, A. S., Nystrand, J., Oakley, C., Obayashi, H., O'Brien, E., Oda, S. X., Ogilvie, C. A., Ohnishi, H., Oide, H., Ojha, I. D., Oka, M., Okada, K., Omiwade, O. O., Onuki, Y., Koop, J. D. Orjuela, Osborn, J. D., Oskarsson, A., Otterlund, I., Ouchida, M., Ozawa, K., Pak, R., Pal, D., Palounek, A. P. T., Pantuev, V., Papavassiliou, V., Park, B. H., Park, I. H., Park, J., Park, J. S., Park, S., Park, S. K., Park, W. J., Pate, S. F., Patel, L., Patel, M., Pei, H., Peng, J. -C., Pereira, H., Perepelitsa, D. V., Perera, G. D. N., Peresedov, V., Peressounko, D. Yu., Perry, J., Petti, R., Pinkenburg, C., Pinson, R., Pisani, R. P., Proissl, M., Purschke, M. L., Purwar, A. K., Qu, H., Rak, J., Rakotozafindrabe, A., Ramson, B. J., Ravinovich, I., Read, K. F., Rembeczki, S., Reuter, M., Reygers, K., Reynolds, D., Riabov, V., Riabov, Y., Richardson, E., Rinn, T., Riveli, N., Roach, D., Roche, G., Rolnick, S. D., Romana, A., Rosati, M., Rosen, C. A., Rosendahl, S. S. E., Rosnet, P., Rowan, Z., Rubin, J. G., Rukoyatkin, P., Ružička, P., Rykov, V. L., Ryu, M. S., Ryu, S. S., Sahlmueller, B., Saito, N., Sakaguchi, T., Sakai, S., Sakashita, K., Sakata, H., Sako, H., Samsonov, V., Sano, M., Sano, S., Sarsour, M., Sato, H. D., Sato, S., Sato, T., Sawada, S., Schaefer, B., Schmoll, B. K., Sedgwick, K., Seele, J., Seidl, R., Sekiguchi, Y., Semenov, V., Sen, A., Seto, R., Sett, P., Sexton, A., Sharma, D., Shaver, A., Shea, T. K., Shein, I., Shevel, A., Shibata, T. -A., Shigaki, K., Shimomura, M., Shohjoh, T., Shoji, K., Shukla, P., Sickles, A., Silva, C. L., Silvermyr, D., Silvestre, C., Sim, K. S., Singh, B. K., Singh, C. P., Singh, V., Skolnik, M., Skutnik, S., Slunečka, M., Smith, W. C., Snowball, M., Solano, S., Soldatov, A., Soltz, R. A., Sondheim, W. E., Sorensen, S. P., Sourikova, I. V., Staley, F., Stankus, P. W., Steinberg, P., Stenlund, E., Stepanov, M., Ster, A., Stoll, S. P., Stone, M. R., Sugitate, T., Suire, C., Sukhanov, A., Sullivan, J. P., Sumita, T., Sun, J., Sziklai, J., Tabaru, T., Takagi, S., Takagui, E. M., Takahara, A., Taketani, A., Tanabe, R., Tanaka, K. H., Tanaka, Y., Taneja, S., Tanida, K., Tannenbaum, M. J., Tarafdar, S., Taranenko, A., Tarján, P., Tennant, E., Themann, H., Thomas, D., Thomas, T. L., Tieulent, R., Timilsina, A., Todoroki, T., Togawa, M., Toia, A., Tojo, J., Tomášek, L., Tomášek, M., Torii, H., Towell, C. L., Towell, R., Towell, R. S., Tram, V-N., Tserruya, I., Tsuchimoto, Y., Tsuji, T., Tuli, S. K., Tydesjö, H., Tyurin, N., Vale, C., Valle, H., van Hecke, H. W., Vargyas, M., Vazquez-Zambrano, E., Veicht, A., Velkovska, J., Vértesi, R., Vinogradov, A. A., Virius, M., Voas, B., Vossen, A., Vrba, V., Vznuzdaev, E., Wagner, M., Walker, D., Wang, X. R., Watanabe, D., Watanabe, K., Watanabe, Y., Watanabe, Y. S., Wei, F., Wei, R., Wessels, J., Whitaker, S., White, A. S., White, S. N., Willis, N., Winter, D., Wolin, S., Woody, C. L., Wright, R. M., Wysocki, M., Xia, B., Xie, W., Xue, L., Yalcin, S., Yamaguchi, Y. L., Yamaura, K., Yang, R., Yanovich, A., Yasin, Z., Ying, J., Yokkaichi, S., Yoo, J. H., Yoon, I., You, Z., Young, G. R., Younus, I., Yu, H., Yushmanov, I. E., Zajc, W. A., Zaudtke, O., Zelenski, A., Zhang, C., Zhou, S., Zimamyi, J., Zolin, L., and Zou, L.

Subjects
Nuclear Experiment
Abstract

Measurements of midrapidity charged particle multiplicity distributions, $dN_{\rm ch}/d\eta$, and midrapidity transverse-energy distributions, $dE_T/d\eta$, are presented for a variety of collision systems and energies. Included are distributions for Au$+$Au collisions at $\sqrt{s_{_{NN}}}=200$, 130, 62.4, 39, 27, 19.6, 14.5, and 7.7 GeV, Cu$+$Cu collisions at $\sqrt{s_{_{NN}}}=200$ and 62.4 GeV, Cu$+$Au collisions at $\sqrt{s_{_{NN}}}=200$ GeV, U$+$U collisions at $\sqrt{s_{_{NN}}}=193$ GeV, $d$$+$Au collisions at $\sqrt{s_{_{NN}}}=200$ GeV, $^{3}$He$+$Au collisions at $\sqrt{s_{_{NN}}}=200$ GeV, and $p$$+$$p$ collisions at $\sqrt{s_{_{NN}}}=200$ GeV. Centrality-dependent distributions at midrapidity are presented in terms of the number of nucleon participants, $N_{\rm part}$, and the number of constituent quark participants, $N_{q{\rm p}}$. For all $A$$+$$A$ collisions down to $\sqrt{s_{_{NN}}}=7.7$ GeV, it is observed that the midrapidity data are better described by scaling with $N_{q{\rm p}}$ than scaling with $N_{\rm part}$. Also presented are estimates of the Bjorken energy density, $\varepsilon_{\rm BJ}$, and the ratio of $dE_T/d\eta$ to $dN_{\rm ch}/d\eta$, the latter of which is seen to be constant as a function of centrality for all systems., Comment: 706 authors, 32 pages, 20 figures, 34 tables, 2004, 2005, 2008, 2010, 2011, and 2012 data. v2 is version accepted for publication in Phys. Rev. C

Published
2015
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37. Electrostatic Potential as a Descriptor of Anti-Bacterial Activities of Some Anacardic Acid Derivatives: A Study Using Density Functional Theory

Author

Tiwari, Manish K. and Mishra, P. C.

Subjects
Physics - Chemical Physics
Abstract

Structures and minimum molecular electrostatic potential (MEP) distributions in anacardic acid and some of its derivatives have been studied by full geometry optimization at the M06-2X/6-31G(d,p), WB97XD/6-31G(d,p) and B3LYP/6-31G(d,p) levels of density functional theory (DFT) in gas phase as well as in DMSO and aqueous solutions. Solvent effect was treated employing the integral equation formalism of the polarizable continuum model. Effects of modifications of the C1-side chain on the minimum MEP values in various regions were studied. Minimum MEP values near the oxygen atoms of the C2-OH group, oxygen or sulfur atoms of the C1-attached urea or thiourea groups and above or below the ring plane considered to be involved in interaction with the receptor were used to perform multiple linear regression. Experimentally observed anti-bacterial activities of these molecules against S. aureus are thus shown to be related to minimum MEP values in the above mentioned regions. Among the three DFT functionals used in the study, the M06-2X functional is found to yield most reliable results. Anti-bacterial activities have been predicted for certain molecules of the class which need to be verified experimentally.

Published
2015

38. Systematic Study of Azimuthal Anisotropy in Cu$+$Cu and Au$+$Au Collisions at $\sqrt{s_{_{NN}}} = 62.4$ and 200 GeV

Author

Adare, A., Afanasiev, S., Aidala, C., Ajitanand, N. N., Akiba, Y., Al-Bataineh, H., Al-Jamel, A., Alexander, J., Aoki, K., Aphecetche, L., Armendariz, R., Aronson, S. H., Asai, J., Atomssa, E. T., Averbeck, R., Awes, T. C., Azmoun, B., Babintsev, V., Baksay, G., Baksay, L., Baldisseri, A., Barish, K. N., Barnes, P. D., Bassalleck, B., Bathe, S., Batsouli, S., Baublis, V., Bauer, F., Bazilevsky, A., Belikov, S., Bennett, R., Berdnikov, Y., Bickley, A. A., Bjorndal, M. T., Boissevain, J. G., Borel, H., Boyle, K., Brooks, M. L., Brown, D. S., Bucher, D., Buesching, H., Bumazhnov, V., Bunce, G., Burward-Hoy, J. M., Butsyk, S., Campbell, S., Chai, J. -S., Chang, B. S., Charvet, J. -L., Chernichenko, S., Chi, C. Y., Chiba, J., Chiu, M., Choi, I. J., Chujo, T., Chung, P., Churyn, A., Cianciolo, V., Cleven, C. R., Cobigo, Y., Cole, B. A., Comets, M. P., Constantin, P., Csanád, M., Csörgő, T., Dahms, T., Das, K., David, G., Deaton, M. B., Dehmelt, K., Delagrange, H., Denisov, A., d'Enterria, D., Deshpande, A., Desmond, E. J., Dietzsch, O., Dion, A., Donadelli, M., Drachenberg, J. L., Drapier, O., Drees, A., Dubey, A. K., Durum, A., Dzhordzhadze, V., Efremenko, Y. V., Egdemir, J., Ellinghaus, F., Emam, W. S., Enokizono, A., En'yo, H., Espagnon, B., Esumi, S., Eyser, K. O., Fields, D. E., Finger, M., Finger, Jr., M., Fleuret, F., Fokin, S. L., Forestier, B., Fraenkel, Z., Frantz, J. E., Franz, A., Frawley, A. D., Fujiwara, K., Fukao, Y., Fung, S. -Y., Fusayasu, T., Gadrat, S., Garishvili, I., Gastineau, F., Germain, M., Glenn, A., Gong, H., Gonin, M., Gosset, J., Goto, Y., de Cassagnac, R. Granier, Grau, N., Greene, S. V., Perdekamp, M. Grosse, Gunji, T., Gustafsson, H. -Å., Hachiya, T., Henni, A. Hadj, Haegemann, C., Haggerty, J. S., Hagiwara, M. N., Hamagaki, H., Han, R., Harada, H., Hartouni, E. P., Haruna, K., Harvey, M., Haslum, E., Hasuko, K., Hayano, R., He, X., Heffner, M., Hemmick, T. K., Hester, T., Heuser, J. M., Hiejima, H., Hill, J. C., Hobbs, R., Hohlmann, M., Holmes, M., Holzmann, W., Homma, K., Hong, B., Horaguchi, T., Hornback, D., Huang, S., Hur, M. G., Ichihara, T., Iinuma, H., Imai, K., Inaba, M., Inoue, Y., Isenhower, D., Isenhower, L., Ishihara, M., Isobe, T., Issah, M., Isupov, A., Jacak, B. V., Jia, J., Jin, J., Jinnouchi, O., Johnson, B. M., Joo, K. S., Jouan, D., Kajihara, F., Kametani, S., Kamihara, N., Kamin, J., Kaneta, M., Kang, J. H., Kanou, H., Kawagishi, T., Kawall, D., Kazantsev, A. V., Kelly, S., Khanzadeev, A., Kikuchi, J., Kim, D. H., Kim, D. J., Kim, E., Kim, Y. -S., Kinney, E., Kiss, Á., Kistenev, E., Kiyomichi, A., Klay, J., Klein-Boesing, C., Kochenda, L., Kochetkov, V., Komkov, B., Konno, M., Kotchetkov, D., Kozlov, A., Král, A., Kravitz, A., Kroon, P. J., Kubart, J., Kunde, G. J., Kurihara, N., Kurita, K., Kweon, M. J., Kwon, Y., Kyle, G. S., Lacey, R., Lai, Y. S., Lajoie, J. G., Lebedev, A., Bornec, Y. Le, Leckey, S., Lee, D. M., Lee, M. K., Lee, T., Leitch, M. J., Leite, M. A. L., Lenzi, B., Li, X., Li, X. H., Lim, H., Liška, T., Litvinenko, A., Liu, M. X., Love, B., Lynch, D., Maguire, C. F., Makdisi, Y. I., Malakhov, A., Malik, M. D., Manko, V. I., Mao, Y., Mašek, L., Masui, H., Matathias, F., McCain, M. C., McCumber, M., McGaughey, P. L., Miake, Y., Mikeš, P., Miki, K., Miller, T. E., Milov, A., Mioduszewski, S., Mishra, G. C., Mishra, M., Mitchell, J. T., Mitrovski, M., Morreale, A., Morrison, D. P., Moss, J. M., Moukhanova, T. V., Mukhopadhyay, D., Murata, J., Nagamiya, S., Nagata, Y., Nagle, J. L., Naglis, M., Nakagawa, I., Nakamiya, Y., Nakamura, T., Nakano, K., Newby, J., Nguyen, M., Norman, B. E., Nouicer, R., Nyanin, A. S., Nystrand, J., O'Brien, E., Oda, S. X., Ogilvie, C. A., Ohnishi, H., Ojha, I. D., Oka, M., Okada, K., Omiwade, O. O., Oskarsson, A., Otterlund, I., Ouchida, M., Ozawa, K., Pak, R., Pal, D., Palounek, A. P. T., Pantuev, V., Papavassiliou, V., Park, J., Park, W. J., Pate, S. F., Pei, H., Peng, J. -C., Pereira, H., Peresedov, V., Peressounko, D. Yu., Pinkenburg, C., Pisani, R. P., Purschke, M. L., Purwar, A. K., Qu, H., Rak, J., Rakotozafindrabe, A., Ravinovich, I., Read, K. F., Rembeczki, S., Reuter, M., Reygers, K., Riabov, V., Riabov, Y., Roche, G., Romana, A., Rosati, M., Rosendahl, S. S. E., Rosnet, P., Rukoyatkin, P., Rykov, V. L., Ryu, S. S., Sahlmueller, B., Saito, N., Sakaguchi, T., Sakai, S., Sakata, H., Samsonov, V., Sato, H. D., Sato, S., Sawada, S., Seele, J., Seidl, R., Semenov, V., Seto, R., Sharma, D., Shea, T. K., Shein, I., Shevel, A., Shibata, T. -A., Shigaki, K., Shimomura, M., Shohjoh, T., Shoji, K., Sickles, A., Silva, C. L., Silvermyr, D., Silvestre, C., Sim, K. S., Singh, C. P., Singh, V., Skutnik, S., Slunečka, M., Smith, W. C., Soldatov, A., Soltz, R. A., Sondheim, W. E., Sorensen, S. P., Sourikova, I. V., Staley, F., Stankus, P. W., Stenlund, E., Stepanov, M., Ster, A., Stoll, S. P., Sugitate, T., Suire, C., Sullivan, J. P., Sziklai, J., Tabaru, T., Takagi, S., Takagui, E. M., Taketani, A., Tanaka, K. H., Tanaka, Y., Tanida, K., Tannenbaum, M. J., Taranenko, A., Tarján, P., Thomas, T. L., Todoroki, T., Togawa, M., Toia, A., Tojo, J., Tomášek, L., Torii, H., Towell, R. S., Tram, V-N., Tserruya, I., Tsuchimoto, Y., Tuli, S. K., Tydesjö, H., Tyurin, N., Vale, C., Valle, H., van Hecke, H. W., Velkovska, J., Vértesi, R., Vinogradov, A. A., Virius, M., Vrba, V., Vznuzdaev, E., Wagner, M., Walker, D., Wang, X. R., Watanabe, Y., Wessels, J., White, S. N., Willis, N., Winter, D., Woody, C. L., Wysocki, M., Xie, W., Yamaguchi, Y. L., Yanovich, A., Yasin, Z., Ying, J., Yokkaichi, S., Young, G. R., Younus, I., Yushmanov, I. E., Zajc, W. A., Zaudtke, O., Zhang, C., Zhou, S., Zimányi, J., and Zolin, L.

Subjects
Nuclear Experiment
Abstract

We have studied the dependence of azimuthal anisotropy $v_2$ for inclusive and identified charged hadrons in Au$+$Au and Cu$+$Cu collisions on collision energy, species, and centrality. The values of $v_2$ as a function of transverse momentum $p_T$ and centrality in Au$+$Au collisions at $\sqrt{s_{_{NN}}}$=200 GeV and 62.4 GeV are the same within uncertainties. However, in Cu$+$Cu collisions we observe a decrease in $v_2$ values as the collision energy is reduced from 200 to 62.4 GeV. The decrease is larger in the more peripheral collisions. By examining both Au$+$Au and Cu$+$Cu collisions we find that $v_2$ depends both on eccentricity and the number of participants, $N_{\rm part}$. We observe that $v_2$ divided by eccentricity ($\varepsilon$) monotonically increases with $N_{\rm part}$ and scales as ${N_{\rm part}^{1/3}}$. The Cu$+$Cu data at 62.4 GeV falls below the other scaled $v_{2}$ data. For identified hadrons, $v_2$ divided by the number of constituent quarks $n_q$ is independent of hadron species as a function of transverse kinetic energy $KE_T=m_T-m$ between $0.1

Published
2014
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43. Genetic divergence for yield contributing characters in F5 families of rice (Oryza sativa L.)

Author

Abinash Mishra, P. C Kole, Soumya Satpathy and Rosevellina Mohanta

Subjects
rice, genetic diversity and d2 analysis, Plant culture, SB1-1110
Abstract

Twenty-one different F5 families derived from eight different crosses involving seven improved parental genotypes of West Bengal were studied for genetic diversity on the basis of yield and its attributing characters. Based on D2 analysis, the 21 families were grouped into 8 clusters. Cluster I consisted maximum of 6 families followed by Cluster II with 4 families. Wilk’s Lambda criterion = 0.7 × 10-7 and V=716.42 with 240 df revealed a highly significant difference among the genotypes for the pooled effects of all the characters. The clusters VII and VIII were mono-familial although there was a common parent. The maximum inter-cluster distance was found between cluster III and IV. Relative contribution of 100-grain weight to the total divergence was highest, followed by plant height, days to 50% flowering and straw yield.

Published
2020
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46. A pharmacologic activator of endothelial KCa channels increases systemic conductance and reduces arterial pressure in an anesthetized pig model

Author

Mishra, Ramesh C, Mitchell, Jamie R, Gibbons-Kroeker, Carol, Wulff, Heike, Belenkie, Israel, Tyberg, John V, and Braun, Andrew P

Subjects
Cardiovascular, Prevention, Heart Disease, Animals, Arterial Pressure, Benzothiazoles, Dose-Response Relationship, Drug, Endothelium, Vascular, Intermediate-Conductance Calcium-Activated Potassium Channels, Male, Small-Conductance Calcium-Activated Potassium Channels, Sus scrofa, Swine, Endothelium, Blood pressure, Conductance, Hemodynamics, KCa channel, Pharmacology and Pharmaceutical Sciences, Cardiovascular System & Hematology
Abstract

SKA-31, an activator of endothelial KCa2.3 and KCa3.1 channels, reduces systemic blood pressure in mice and dogs, however, its effects in larger mammals are not well known. We therefore examined the hemodynamic effects of SKA-31, along with sodium nitroprusside (SNP), in anesthetized, juvenile male domestic pigs. Experimentally, continuous measurements of left ventricular (LV), aortic and inferior vena cava (IVC) pressures, along with flows in the ascending aorta, carotid artery, left anterior descending coronary artery and renal artery, were performed during acute administration of SKA-31 (0.1, 0.3, 1.0, 3.0 and 5.0mg/ml/kg) and a single dose of SNP (5.0 μg/ml/kg). SKA-31 dose-dependently reduced mean aortic pressure (mPAO), with the highest dose decreasing mPAO to a similar extent as SNP (-23 ± 3 and -28 ± 4 mmHg, respectively). IVC pressure did not change. Systemic conductance and conductance in coronary and carotid arteries increased in response to SKA-31 and SNP, but renal artery conductance was unaffected. There was no change in either LV stroke volume (SV) or heart rate (versus the preceding control) for any infusion. With no change in SV, drug-evoked decreases in LV stroke work (SW) were attributed to reductions in mPAO (SW vs. mPAO, r(2)=0.82, P

Published
2016

48. Transverse-energy distributions at midrapidity in $p$$+$$p$, $d$$+$Au, and Au$+$Au collisions at $\sqrt{s_{_{NN}}}=62.4$--200~GeV and implications for particle-production models

Author

Adler, S. S., Afanasiev, S., Aidala, C., Ajitanand, N. N., Akiba, Y., Al-Jamel, A., Alexander, J., Aoki, K., Aphecetche, L., Armendariz, R., Aronson, S. H., Averbeck, R., Awes, T. C., Azmoun, B., Babintsev, V., Baldisseri, A., Barish, K. N., Barnes, P. D., Bassalleck, B., Bathe, S., Batsouli, S., Baublis, V., Bauer, F., Bazilevsky, A., Belikov, S., Bennett, R., Berdnikov, Y., Bjorndal, M. T., Boissevain, J. G., Borel, H., Boyle, K., Brooks, M. L., Brown, D. S., Bruner, N., Bucher, D., Buesching, H., Bumazhnov, V., Bunce, G., Burward-Hoy, J. M., Butsyk, S., Camard, X., Campbell, S., Chai, J. -S., Chand, P., Chang, W. C., Chernichenko, S., Chi, C. Y., Chiba, J., Chiu, M., Choi, I. J., Choudhury, R. K., Chujo, T., Cianciolo, V., Cleven, C. R., Cobigo, Y., Cole, B. A., Comets, M. P., Constantin, P., Csanád, M., Csörgő, T., Cussonneau, J. P., Dahms, T., Das, K., David, G., Deák, F., Delagrange, H., Denisov, A., d'Enterria, D., Deshpande, A., Desmond, E. J., Devismes, A., Dietzsch, O., Dion, A., Drachenberg, J. L., Drapier, O., Drees, A., Dubey, A. K., Durum, A., Dutta, D., Dzhordzhadze, V., Efremenko, Y. V., Egdemir, J., Enokizono, A., En'yo, H., Espagnon, B., Esumi, S., Fields, D. E., Finck, C., Fleuret, F., Fokin, S. L., Forestier, B., Fox, B. D., Fraenkel, Z., Frantz, J. E., Franz, A., Frawley, A. D., Fukao, Y., Fung, S. -Y., Gadrat, S., Gastineau, F., Germain, M., Glenn, A., Gonin, M., Gosset, J., Goto, Y., de Cassagnac, R. Granier, Grau, N., Greene, S. V., Perdekamp, M. Grosse, Gunji, T., Gustafsson, H. -Å., Hachiya, T., Henni, A. Hadj, Haggerty, J. S., Hagiwara, M. N., Hamagaki, H., Hansen, A. G., Harada, H., Hartouni, E. P., Haruna, K., Harvey, M., Haslum, E., Hasuko, K., Hayano, R., He, X., Heffner, M., Hemmick, T. K., Heuser, J. M., Hidas, P., Hiejima, H., Hill, J. C., Hobbs, R., Holmes, M., Holzmann, W., Homma, K., Hong, B., Hoover, A., Horaguchi, T., Hur, M. G., Ichihara, T., Iinuma, H., Ikonnikov, V. V., Imai, K., Inaba, M., Inuzuka, M., Isenhower, D., Isenhower, L., Ishihara, M., Isobe, T., Issah, M., Isupov, A., Jacak, B. V., Jia, J., Jin, J., Jinnouchi, O., Johnson, B. M., Johnson, S. C., Joo, K. S., Jouan, D., Kajihara, F., Kametani, S., Kamihara, N., Kaneta, M., Kang, J. H., Katou, K., Kawabata, T., Kawagishi, T., Kazantsev, A. V., Kelly, S., Khachaturov, B., Khanzadeev, A., Kikuchi, J., Kim, D. J., Kim, E., Kim, E. J., Kim, G. -B., Kim, H. J., Kim, Y. -S., Kinney, E., Kiss, Á., Kistenev, E., Kiyomichi, A., Klein-Boesing, C., Kobayashi, H., Kochenda, L., Kochetkov, V., Kohara, R., Komkov, B., Konno, M., Kotchetkov, D., Kozlov, A., Kroon, P. J., Kuberg, C. H., Kunde, G. J., Kurihara, N., Kurita, K., Kweon, M. J., Kwon, Y., Kyle, G. S., Lacey, R., Lajoie, J. G., Lebedev, A., Bornec, Y. Le, Leckey, S., Lee, D. M., Lee, M. K., Leitch, M. J., Leite, M. A. L., Li, X. H., Lim, H., Litvinenko, A., Liu, M. X., Maguire, C. F., Makdisi, Y. I., Malakhov, A., Malik, M. D., Manko, V. I., Mao, Y., Martinez, G., Masui, H., Matathias, F., Matsumoto, T., McCain, M. C., McGaughey, P. L., Miake, Y., Miller, T. E., Milov, A., Mioduszewski, S., Mishra, G. C., Mitchell, J. T., Mohanty, A. K., Morrison, D. P., Moss, J. M., Moukhanova, T. V., Mukhopadhyay, D., Muniruzzaman, M., Murata, J., Nagamiya, S., Nagata, Y., Nagle, J. L., Naglis, M., Nakamura, T., Newby, J., Nguyen, M., Norman, B. E., Nyanin, A. S., Nystrand, J., O'Brien, E., Ogilvie, C. A., Ohnishi, H., Ojha, I. D., Okada, K., Omiwade, O. O., Oskarsson, A., Otterlund, I., Oyama, K., Ozawa, K., Pal, D., Palounek, A. P. T., Pantuev, V., Papavassiliou, V., Park, J., Park, W. J., Pate, S. F., Pei, H., Penev, V., Peng, J. -C., Pereira, H., Peresedov, V., Peressounko, D. Yu., Pierson, A., Pinkenburg, C., Pisani, R. P., Purschke, M. L., Purwar, A. K., Qu, H., Qualls, J. M., Rak, J., Ravinovich, I., Read, K. F., Reuter, M., Reygers, K., Riabov, V., Riabov, Y., Roche, G., Romana, A., Rosati, M., Rosendahl, S. S. E., Rosnet, P., Rukoyatkin, P., Rykov, V. L., Ryu, S. S., Sahlmueller, B., Saito, N., Sakaguchi, T., Sakai, S., Samsonov, V., Sanfratello, L., Santo, R., Sato, H. D., Sato, S., Sawada, S., Schutz, Y., Semenov, V., Seto, R., Sharma, D., Shea, T. K., Shein, I., Shibata, T. -A., Shigaki, K., Shimomura, M., Shohjoh, T., Shoji, K., Sickles, A., Silva, C. L., Silvermyr, D., Sim, K. S., Singh, C. P., Singh, V., Skutnik, S., Smith, W. C., Soldatov, A., Soltz, R. A., Sondheim, W. E., Sorensen, S. P., Sourikova, I. V., Staley, F., Stankus, P. W., Stenlund, E., Stepanov, M., Ster, A., Stoll, S. P., Sugitate, T., Suire, C., Sullivan, J. P., Sziklai, J., Tabaru, T., Takagi, S., Takagui, E. M., Taketani, A., Tanaka, K. H., Tanaka, Y., Tanida, K., Tannenbaum, M. J., Taranenko, A., Tarján, P., Thomas, T. L., Togawa, M., Tojo, J., Torii, H., Towell, R. S., Tram, V-N., Tserruya, I., Tsuchimoto, Y., Tuli, S. K., Tydesjö, H., Tyurin, N., Uam, T. J., Vale, C., Valle, H., van Hecke, H. W., Velkovska, J., Velkovsky, M., Vértesi, R., Veszprémi, V., Vinogradov, A. A., Volkov, M. A., Vznuzdaev, E., Wagner, M., Wang, X. R., Watanabe, Y., Wessels, J., White, S. N., Willis, N., Winter, D., Wohn, F. K., Woody, C. L., Wysocki, M., Xie, W., Yanovich, A., Yokkaichi, S., Young, G. R., Younus, I., Yushmanov, I. E., Zajc, W. A., Zaudtke, O., Zhang, C., Zhou, S., Zimányi, J., Zolin, L., and Zong, X.

Subjects
Nuclear Experiment
Abstract

Measurements of the midrapidity transverse energy distribution, $d\Et/d\eta$, are presented for $p$$+$$p$, $d$$+$Au, and Au$+$Au collisions at $\sqrt{s_{_{NN}}}=200$ GeV and additionally for Au$+$Au collisions at $\sqrt{s_{_{NN}}}=62.4$ and 130 GeV. The $d\Et/d\eta$ distributions are first compared with the number of nucleon participants $N_{\rm part}$, number of binary collisions $N_{\rm coll}$, and number of constituent-quark participants $N_{qp}$ calculated from a Glauber model based on the nuclear geometry. For Au$+$Au, $\mean{d\Et/d\eta}/N_{\rm part}$ increases with $N_{\rm part}$, while $\mean{d\Et/d\eta}/N_{qp}$ is approximately constant for all three energies. This indicates that the two component ansatz, $dE_{T}/d\eta \propto (1-x) N_{\rm part}/2 + x N_{\rm coll}$, which has been used to represent $E_T$ distributions, is simply a proxy for $N_{qp}$, and that the $N_{\rm coll}$ term does not represent a hard-scattering component in $E_T$ distributions. The $dE_{T}/d\eta$ distributions of Au$+$Au and $d$$+$Au are then calculated from the measured $p$$+$$p$ $E_T$ distribution using two models that both reproduce the Au$+$Au data. However, while the number-of-constituent-quark-participant model agrees well with the $d$$+$Au data, the additive-quark model does not., Comment: 391 authors, 24 pages, 19 figures, and 15 Tables. Submitted to Phys. Rev. C. Plain text data tables for the points plotted in figures for this and previous PHENIX publications are publicly available at http://www.phenix.bnl.gov/papers.html

Published
2013
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