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1. Hypothyroidism and coeliac disease-A family study

Author

N. Manning, M. I. Drury, D. McCarthy, and J. P. R. Rees

Subjects
Adult, Male, medicine.medical_specialty, Pediatrics, endocrine system diseases, Adolescent, business.industry, General Medicine, medicine.disease, Coeliac disease, Celiac Disease, Endocrinology, Hypothyroidism, Internal medicine, Child, Preschool, medicine, Humans, IgA deficiency, Female, business, Child
Abstract

A family of ten children is described. Five were hypothyroid and two had coeliac disease, both disorders coexisting in one child. IgA deficiency was present in the mother and one child.

Published
2016

2. A positive Monospot test in a diabetic with sarcoidosis

Author

Brian C. Lalor, M. I. Drury, and John Feely

Subjects
Adult, Male, medicine.medical_specialty, Sarcoidosis, business.industry, General Medicine, medicine.disease, Dermatology, Rubella, Lymphoma, Test (assessment), Diabetes Complications, Rheumatoid arthritis, medicine, Humans, False Positive Reactions, Infectious Mononucleosis, Pancreatic carcinoma, business, Malaria
Abstract

Introduction The Monospot test for infectious mononuclsosis is both specific and sensitive (Seitanidis, 1969; Davidsohn, 1970; Basson et al., 1969) but false positive results have been reported in malaria (Reed, 1973), pancreatic carcinoma (Sadoff et al., 1971), rheumatoid arthritis (Horwitz et al., 1973), lymphoma (Wolf, 1969) end rubella (Phillips, 1972; Tri and Herbst, 1973). The purpose of this communication is to report a persistently positive Mcnospot test in a diabetic with sarcoidosis.

Published
2016

3. Inaugural national scientific medical meeting

Author

P. Noonan Walsh, C. Conliffe, A. S. Abdulkadir, P. Kelehan, R. Conroy, M. Foley, P. Lenehan, J. F. Murphy, J. Stronge, B. Cantwell, C. Wright, M. Millward, M. Carpenter, T. Lennard, R. Wilson, C. Home, A. R. Corbett, G. O’Sullivan, J. K. Collins, M. Doran, E. W. M. McDermott, P. Mercer, P. Smyth, N. J. O’Higgins, M. J. Duffy, D. Reilly, E. McDermott, C. Faul, J. J. Fennelly, N. O’Higgins, S. Lowry, H. Russell, R. Atkinson, I. Hickey, F. O’Brien, A. O’Mahony, M. O’Donoghue, M. Pomeroy, E. S. Prosser, F. Barker, M. Casey, K. Carroll, M. Davis, G. Duffy, R. O’Kennedy, P. P. A. Smyth, D. O’Carroll, A. M. Hetherton, E. Coveney, V. McAlister, M. J. Murray, D. J. Brayden, A. O’Hora, J. Street, J. O’Leary, A. M. Pollock, M. Crowley, I. Healy, J. Murphy, R. Landers, L. Burke, D. O’Brien, P. Annis, J. Hogan, W. Kealy, F. A. Lewis, C. T. Doyle, M. Callaghan, A. Whelan, C. Feighery, B. Bresnihan, D. Kelleher, G. Reams, A. Murphy, N. Hall, E. B. Casey, D. Mulherin, E. Doherty, G. Yanni, E. Wallace, J. Jackson, M. Bennett, O. Tighe, H. Mulcahy, D. O’Donoghue, D. T. Croke, R. J. Cahill, S. Beattie, H. Hamilton, C. O’Morain, B. Corridan, R. A. Collins, C. A. O’Morain, E. Fitzgerald, J. M. Gilvarry, M. Leader, J. F. Fielding, B. T. Johnson, S. A. Lewis, A. H. G. Love, B. T. Johnston, J. S. A. Collins, R. J. McFarland, P. W. Johnston, B. J. Collins, C. M. Kilgallen, G. M. Murphy, G. M. Markey, J. A. McCormack, R. C. Curry, T. C. M. Morris, H. D. Alexander, S. Edgar, M. Treacy, M. A. O’Connell, D. G. Weir, J. Sheehan, G. O’Loughlin, O. Traynor, N. Walsh, H. X. Xia, M. A. Daw, C. T. Keane, C. Dupont, G. Gibson, E. McGinnity, J. Walshe, M. Carmody, J. Donohoe, P. McGrath, R. O’Moore, E. Kieran, S. Rogers, K. E. McKenna, M. Walsh, E. A. Bingham, A. E. Hughes, N. C. Nevin, D. J. Todd, C. F. Stanford, M. E. Callender, D. Burrows, D. G. Paige, G. E. Allen, D. P. O’Brien, D. B. Gough, C. Phelan, H. F. Given, S. Zia Kamal, S. Kehoe, S. Coldicott, D. Luesley, K. Ward, H. F. MacDonnell, S. Mullins, I. Gordon, L. A. Norris, M. Devitt, J. Bonnar, S. C. Sharma, B. L. Sheppard, R. Fitzsimons, S. Kingston, M. Garvey, H. M. C. V. Hoey, J. F. T. Glasgow, R. Moore, P. H. Robinson, E. Murphy, J. F. A. Murphy, A. E. Wood, P. Sweeney, M. Neligan, D. MacLeod, G. Cunnane, P. Kelly, P. Corcoran, L. Clancy, R. M. Drury, M. I. Drury, D. Powell, R. G. R. Firth, T. Jones, B. F. Ferris, W. O’Flynn, J. O’Donnell, S. M. Kingston, F. Cunningham, G. M. E. Hinds, D. R. McCluskey, F. Howell, M. O’Mahony, J. Devlin, O. O’Reilly, C. Buttanshaw, S. Jennings, E. R. Keane, C. Foley-Nolan, F. M. Ryan, M. Taylor, R. A. Lyons, F. O’Kelly, J. Mason, D. Carroll, K. Doherty, M. Flynn, R. O’Dwyer, J. J. Gilmartin, C. F. McCarthy, C. Armstrong, D. Mannion, T. Feely, G. Fitzpatrick, C. M. Cooney, J. Chin Aleong, R. Rooney, J. Lyons, D. M. Phelan, G. P. Joshi, S. M. McCarroll, W. P. Blunnie, T. M. O’Brien, D. C. Moriarty, J. Brangan, C. P. Kelly, P. Kenny, H. Gallagher, E. McGovern, D. Luke, D. Lowe, T. Rice, D. Phelan, J. B. Lyons, F. M. Lyons, D. M. McCoy, J. McGinley, J. Hurley, P. McDonagh, J. J. Crowley, S. M. Donnelly, M. Tobin, O. Fitzgerald, B. J. Maurer, P. J. Quigley, G. King, E. B. Duly, T. R. Trinick, D. Boyle, G. B. Wisdom, F. Geoghegan, P. B. Collins, C. Goss, K. Younger, P. Mathias, I. Graham, S. W. MacGowan, P. Sidhu, D. J. McEneaney, D. J. Cochrane, A. A. J. Adgey, J. M. Anderson, J. Moriarty, C. Fahy, A. Lavender, L. Lynch, C. McGovern, A. M. Nugent, D. Neely, I. Young, I. McDowell, M. O’Kane, D. P. Nicholls, D. McEneaney, D. P. Nichols, N. P. S. Campbell, G. C. Campbell, M. I. Halliday, A. F. O’Donnell, M. Lonergan, T. Ahearne, J. O’Neill, T. V. Keaveny, D. Ramsbottom, D. Boucher-Hayes, R. Sheahan, M. T. Garadaha, D. Kidney, P. Freyne, G. Gearty, P. Crean, H. P. Singh, M. Hargrove, K. Subareddy, J. P. Hurley, W. O’Rourke, C. O’Connor, M. X. FitzGerald, T. J. McDonnell, R. Chan, J. Stinson, L. Hemeryck, J. Feely, M. P. Chopra, A. Sivner, S. M. Sadiq, E. Abernathy, L. Plant, C. P. Bredin, P. Hickey, G. Slevin, K. McCrory, M. Long, P. Conlon, F. Walker, P. Fitzgerald, S. J. O’Neill, C. M. O’Connor, C. Quigley, S. Donnelly, A. Southey, E. Healy, F. Mulcahy, D. J. Lyons, J. Keating, C. O’Mahony, D. Roy, A. G. Shattock, I. B. Hillary, A. Waiz, R. Hossain, B. Chakraborthy, L. P. Clancy, L. O’Reilly, C. Byrne, E. Costello, E. O’Shaughnessy, B. Cryan, J. Farrell, J. J. Walshe, G. J. Mellotte, C. A. Ho, S. H. Morgan, M. R. Bending, and J. Bonner

Subjects
Medical education, business.industry, Medicine, General Medicine, business, Article
Published
1993
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4. A controlled study of prolonged study with semi-synthetic human insulin

Author

R. Drury, M. I. Drury, D. Cregan, W. G. Reeves, P. Keenan, and M. McEvoy

Subjects
Adult, Blood Glucose, Male, medicine.medical_specialty, Adolescent, Body weight, Semi synthetic, Clinical study, Random Allocation, Internal medicine, Human insulin, Humans, Insulin, Medicine, Clinical Trials as Topic, Insulin, Regular, Pork, business.industry, Monocomponent insulin, Porcine insulin, General Medicine, Middle Aged, Total Daily Dose, Insulin, Long-Acting, Diabetes Mellitus, Type 1, Endocrinology, Type i diabetes, Female, business
Abstract

Along term clinical study of semi-synthetic human monocomponent insulin (short and intermediate formulations) was undertaken in 32 patients with Type I diabetes. After a two-month run-in period, patients were randomised to either human or porcine insulin and blood glucose profiles and haemoglobin A1 were measured two monthly. Thirty-one patients (15—porcine, 16—human) have been treated for 12 months. There were no statistically significant differences between the two insulins in terms of fasting blood glucose (8.9±4.8 mmol/l porcine, 9.5±5.0 mmol/l human), haemoglobin A1 (10.4±2.6% porcine, 10.3±1.3 human), total daily dose (46.5±2.1 U porcine, 38.9±14.8 U human) or body weight (70.4±9.3 Kg porcine, 67.5±9.5 Kg human). Sera from both groups were tested for IgG binding to human and porcine insulin. In the patients treated with human insulin, binding to human insulin was 4.5±2.2μg/l at randomisation and 3.9±2.1 μg/l after six months. For the porcine group, binding to human insulin was 7.6±6.6 μg/l at randomisation and 7.8±7.2 μg/l after six months. These changes were not statistically significant. Thus no difference was found between patients treated with human or porcine insulin.

Published
1983
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5. Proceedings of the 12th Annual Meeting of the Irish Endocrine Society, Belfast, October 23rd and 24th 1987

Author

C. M. Ritchie, D. R. Hadden, A. L. Kennedy, B. Sheridan, A. B. Atkinson, D. P. Murray, J. B. Ferriss, D. J. O’Sullivan, H. C. P. Leslie, G. Roberts, D. R. McCance, J. A. McKnight, B. McLaughlin, P. Barrett, J. G. Devlin, S. C. Fitzpatrick, T. J. McKenna, T. R. J. Lappin, G. E. Elder, J. H. Brown, T. Taylor, J. M. Bridges, D. O’Shea, M. Byrne, D. Powell, S. K. Cunningham, K. W. Moles, A. Varghese, K. D. Buchanan, D. Carson, S. Laverty, W. R. McKane, A. B. Stevens, E. Duly, W. J. Andrews, P. M. Bell, J. R. Hayes, R. W. Henry, R. G. Firth, R. A. Rizza, J. A. O’Hare, K. L. Minaker, G. S. Keneilly, J. W. Rowe, Johanna A. Pallotta, J. B. Young, R. Firth, P. Bell, I. Hansen, R. Rizza, A. E. Corcoran, P. P. A. Smyth, A. Cranny, M. J. Cullen, C. J. O’Brien, S. Vento, T. Cundy, A. L. W. F. Eddleston, J. Folan, J. P. Gosling, P. F. Fottrell, M. M. Finn, D. J. King, P. Keenan, E. Gayer, P. Salmon, G. H. Tomkin, and M. I. Drury

Subjects
medicine.medical_specialty, Irish, business.industry, Family medicine, language, Medicine, Endocrine system, General Medicine, business, language.human_language
Published
1988
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6. The immunogenic properties of a highly purified insulin preparation

Author

M. I. Drury and N. Manning

Subjects
Adult, Male, medicine.medical_specialty, Time Factors, Adolescent, Insulin Antibodies, medicine.medical_treatment, Antibody level, Insulin Antibody, Internal medicine, Diabetes Mellitus, medicine, Humans, Insulin, In patient, Child, Aged, biology, business.industry, Porcine insulin, General Medicine, Middle Aged, humanities, Endocrinology, biology.protein, Female, Antibody, business, Antibody formation
Abstract

Twenty patients who had never previously received insulin were treated with a highly purified preparation (NPH LEO in R.I. quality). Insulin antibody estimations were performed over a 14 to 19 month period. Detectable amounts of antibodies were formed by 18 of the 20 patients. The levels were lower than those found in patients on conventional insulins but moderate levels were found in 7 patients. No correlation was found between the development of antibodies and changes in insulin requirement.

Published
1979
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7. Irish Nephrological Society≿s Meeting

Author

Peter G. Blake, Susan Hanson, Barry Duggan, Adam L. Linton, D. Mulcahy, M. I. Drury, Vincent Chester, J. Donohoe, Robert M. Lindsay, Peter J. Garrett, Ivo Drury, W. F. O'dwyer, J F Donohoe, Cornelius Cronin, J. Kenny, Stephen Eustace, B. Keogh, T. B. Counihan, Denis Gill, J. Donoghue, John S. Fennell, John Dononoe, J. Dunn, M. J. Sibbald, Rosemarie Freaney, John S. Hanson, Garrett P, Susan Spencer, J. Frank Walker, Dermot Murnaghan, J. A. Brian Keogh, Francis P. Muldowney, Michael Carmody, and Frank Ryan

Subjects
Irish, business.industry, Law, language, Medicine, General Medicine, business, language.human_language
Published
1985
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8. The Dublin School of Clinical Medicine

Author

M. I. Drury

Subjects
History, 17th Century, medicine.medical_specialty, business.industry, Family medicine, medicine, Humans, Optometry, General Medicine, Philosophy, Medical, business, Ireland, Schools, Medical, Education
Published
1988
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9. Irish Endocrine Society

Author

T. McDonnell, M. J. Cullen, B. Griffin, O. Earley, J. McWeeney, J. O’Donnell, P. Finnegan, D. Sugrue, S. J. Heffernan, E. O’Malley, M. I. Drury, L. Scott, G. H. Tomkin, H. Walsh, C. Quigley, P. A. Sullivan, Helga Gonggrijp, M. J. Crowley, J. B. Ferriss, D. J. O’Sullivan, Ruth O’Kelly, Fergal Magee, T. Joseph McKenna, P. J. Garrett, Claire Langan, Eithne Mulloy, M. Henry, J. K. McMullen, A. P. Grant, C. E. Tindall, J. G. Daly, J. R. Hayes, Joy Ardili, I. G. Banks, L. Herberg, J. M. Sloan, D. Buchanan, P. Maxwell, C. Carland, T. C. Lee, F. Mulera-Kwehangaana, J. Ardili, Denis G. Mehigan, David J. Bouchier-Hayes, John L. Cameron, D. Cannon, J. Barron, J. Harney, M. Coughlan, D. Powell, O ’Herlihy, D. M. Danks, J. A. O’Hare, M. Twomey, J. Ferriss, J. A. O’HARE, T. S. Callaghan, K. D. Buchanan, M. M. T. O’Hare, P. Jeffers, E. M. Mcllrath, T. L. Kennedy, A, A. McConnell, J. A. Curtis, L. Kennedy, R. Beacom, D. Carson, S. L Campbell, P. B. Johnston, P. P. A. Smyth, D. Neylan, G. J. Duffy, T. J. McKenna, J. McKiernan, and M. Curtin

Subjects
Irish, business.industry, engineering, language, Medicine, Endocrine system, General Medicine, Cork, engineering.material, Ancient history, business, language.human_language
Published
1982
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10. Book reviews

Author

Denis K. O’Donovan, C. S. Breathnach, Stephen Reid, John Barragry, F. O. C. Meenan, F. H. Moore, J. J. Fennelly, D. M. Mitchell, Pierse Hurley, W. A. L. MacGowan, M. I. Drury, R. Mulcahy, Brian F. Regan, R. J. W. Ryder, Gerald E. Edwards, and Michael Solomons

Subjects
General Medicine
Published
1976
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11. Pregnancy in the clinical diabetic

Author

M. I. Drury

Subjects
Adult, Pregnancy, medicine.medical_specialty, Labor, Obstetric, Obstetrics, business.industry, Infant, Newborn, Pregnancy in Diabetics, General Medicine, medicine.disease, medicine, Humans, Female, business, Fetal Death
Published
1979
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12. Book reviews

Author

M. I. Drury, R. P. Kernan, K. C. Condon, Michael R. Butler, Joseph Barnes, J. McCarthy, M. Mulcahy, G. J. Duffy, and Geoffrey J. Bourke

Subjects
General Medicine
Published
1977
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13. Occasional topic

Author

M. I. Drury

Subjects
History, Irish, language, PARRY, General Medicine, Medical science, language.human_language, Classics
Abstract

In 1835 Robert Graves, one of the jewels in the crown of Irish medicine, described the condition with which his name is now permanently associated. Claims to priority of Parry and Basedow are discussed. Reference is made to some of Graves many contributions to medicine, amongst them being the establishment with Dr. Kane of the Dublin Journal of Medical Science in 1832 which became the Irish Journal of Medical Science in 1922. It seemed fitting, therefore, to mark the 150th anniversary of Graves’ original description by reviewing a personal experience of 1,174 cases of hyperthyroidism treated in Graves’ native country during the past thirty-one years.

Published
1985
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14. Book reviews

Author

J. Dermot O'Flynn, John Barragry, P. G. S. Beckett, M. I. Drury, J. J. Fennelly, Michael P. Brady, Liam G. O'Connell, Robert P. Towers, and O. C. Ward

Subjects
General Medicine
Published
1974
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15. Diabetic stiff hand syndrome

Author

G. Fitzgerald, M. McEvoy, M. I. Drury, Declan D. Sugrue, and J. Dempsey

Subjects
Adult, Male, Hand deformity, medicine.medical_specialty, Pediatrics, business.industry, Incidence (epidemiology), General Medicine, medicine.disease, Limited joint mobility, Surgery, Diabetes Complications, medicine.anatomical_structure, Diabetic stiff hand syndrome, Diabetes mellitus, Hand Deformities, Acquired, medicine, Humans, Female, Carpal tunnel, Carpal tunnel syndrome, business, Sensory nerve conduction velocity
Abstract

The association of diabetes mellitus and ‘stiff hands’ is well documented. We report on twenty-three cases of the syndrome and the incidence of diabetic complications in this group relative to controls matched for age, sex, duration of diabetes and therapy.

Published
1983
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16. Book reviews

Author

Joan M. T. MacCarthy, O. K. Shorten, Robert P. Towers, Michael Solomons, Risteard Mulcahy, P. Keelan, J. G. Devlin, Desmond F. Duff, Conal Hooper, S. O’Riain, W. F. O’Dwyer, Richard T. Nolan, M. I. Drury, and J. D. O’Flynn

Subjects
General Medicine
Published
1977
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17. Long term follow-up of hyperthyroid patients treated by subtotal thyroidectomy

Author

M. I. Drury, Declan D. Sugrue, S J Heffernan, M. McEvoy, and E O'Malley

Subjects
Adult, Male, Reoperation, medicine.medical_specialty, Time Factors, Adolescent, endocrine system diseases, Long term follow up, Hyperthyroidism, Unilateral vocal cord paralysis, Diffuse hyperplasia, Hypothyroidism, Recurrence, medicine, Humans, Hypocalcaemia, Relapse risk, Child, Aged, Hypocalcemia, business.industry, Perioperative, Subtotal thyroidectomy, Middle Aged, Multinodular goitre, medicine.disease, Surgery, Thyroidectomy, Female, business, Vocal Cord Paralysis, Follow-Up Studies
Abstract

The early and long term complications of subtotal thyroidectomy in 306 hyperthyroid patients (multinodular goitre and diffuse hyperplasia) followed for up to 30 yr are reviewed. There were no perioperative deaths. Sixteen patients (5·2 per cent) had transient symptomatic hypocalcaemia, while 9 (2·9 per cent) had permanent hypocalcaemia. Permanent unilateral vocal cord paralysis occurred in 11 (3·6 per cent) patients (1·8 per cent of nerves at risk). Cumulative per cent (± s.e.m.) relapse and hypothyroid rates at 30yr (life-table analysis) were 15·6 ± 2·4 per cent and 20·5 ± 2·1 per cent, respectively. Lifelong follow-up of post-thyroidectomy patients is mandatory because of the risk of relapse or hypothyroidism.

Published
1983
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18. A Randomized Trial of the Efficacy and Acceptability of a Pen Injector

Author

D. J. O’Sullivan, E. Gayer, D. P. Murray, G. H. Tomkin, Peter Salmon, P. Keenan, and M. I. Drury

Subjects
Adult, Male, medicine.medical_specialty, Ultralente, Injections, Subcutaneous, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Drug Administration Schedule, law.invention, Random Allocation, Endocrinology, Patient satisfaction, Randomized controlled trial, law, Surveys and Questionnaires, Diabetes mellitus, Internal Medicine, medicine, Humans, Insulin, Syringe, Glycated Hemoglobin, Clinical Trials as Topic, Insulin, Regular, Pork, business.industry, Insulin pen, Consumer Behavior, medicine.disease, Recombinant Proteins, Surgery, Insulin, Long-Acting, Regimen, Diabetes Mellitus, Type 1, Anesthesia, Female, business
Abstract

A controlled trial of pen injection of insulin was performed in 78 patients, with assessment of metabolic control and lifestyle. After a 6-week run-in period, during which control was optimized, the patients were randomized, either to stay on a twice daily insulin regimen (n = 37), or to change to a three times daily pen regimen with human ultralente at night (n = 41). Over the 20 weeks, there was no significant change in mean glycosylated haemoglobin (syringe, mean +/- SD, 11.1 +/- 2.5% to 10.9 +/- 2.0%; pen, 11.3 +/- 2.6% to 11.2 +/- 2.0%), in blood glucose profiles or in frequency of hypoglycaemic attacks in either group. A self-completed questionnaire demonstrated high patient satisfaction with the pen injector (NovoPen), 78% for effect on lifestyle and 81% for increased flexibility. Ninety-five percent preferred the pen injector regimen to conventional treatment and stayed on it.

Published
1988
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19. The rate of change of haemoglobin A1 in response to altered plasma glucose levels in insulin dependent diabetics

Author

M. W. France, R. Baumgart, S. Murnaghan, D. UaConaill, M. Pereira, and M. I. Drury

Subjects
Blood Glucose, Plasma glucose, medicine.medical_specialty, business.industry, Insulin, medicine.medical_treatment, Glucose Measurement, Hemoglobin A, General Medicine, Newly diagnosed, Endocrinology, Internal medicine, Diabetes Mellitus, Humans, Medicine, Glycosylated haemoglobin, Insulin dependent, business, Diabetic control
Abstract

Glycosylated haemoglobin, haemoglobin A1 (Hb A1) and glucose were measured in 16 newly diagnosed diabetics during initial stabilisation and in the following 20 weeks. Hb A1 levels fell slowly, significant change still occurring even 8 weeks after the start of insulin therapy. Glucose levels of the group did not change significantly after the initial response to insulin. In addition 2 hourly Hb A1 and glucose measurements were made over 24 hours in 3 poorly controlled diabetics. Large fluctuations in glucose levels during this period did not affect the Hb A1 levels. Previous reports of rapid glycosylation of haemoglobin are considered in the light of these observations. The usefulness of Hb A1 as an index of diabetic control is discussed.

Published
1980
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20. Book reviews

Author

J. J. Fennelly, John Greally, David Powell, S. Heffernan, Michael Swallow, M. I. Drury, J. H. Walsh, John McKenna, and J. B. Prendiville

Subjects
General Medicine
Published
1974
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21. Irish endocrine society

Author

A. I. Traub, J. A. Weaver, D. Neylan, K. Wilson, D. J. Carson, B. M. Twomey, W. C. J. Collins, J. R. Hayes, H. Kennedy, Hadden, B. Sawhney, T. J. O’hanrahan, A. L. Woods, Vincent DeQuattro, D. Middleton, W. Postlethwaite, L. Kennedy, P. Keenan, M. Murphy, J. D. Baily, D. Brady, Patrick A. Sullivan, B. Magee, J. B. Ferriss, P. P. A. Smyth, S. Sequeira, T. J. McKenna, B. Svheridan, Andrew Foti, B. Sheridan, D. Cregan, Gerald H. Tomkin, P. Skrabanek, R. R. Drury, T. L. Kennedy, R. B. Welbourn, D. J. O’Sullivan, J. A. O’Hare, W. G. Reeves, D. R. Hadden, E. A. Wilson, D. Powell, Noirin Noonan, G. J. Joplin, J. Bain, Michael Hutchinson, J. D. Merrett, M. Byrne, P. H. Osterberg, S. J. Heffernan, A. L. T. Blair, D. K. O’Donovan, P. Dervan, D. A. D. Montgomery, K. Manolas, J. A. Curtis, R. Beacom, W. Thompson, N. M. McMullan, S. M. Kingston, T. J. Lyons, N. McMullan, P. M. Bell, M. I. Drury, J. S. Woodhead, A. B. Atkinson, E. Tempany, and D. G. Sinnamon

Subjects
Irish, business.industry, language, Library science, Medicine, Endocrine system, General Medicine, business, language.human_language
Published
1984
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22. Antibody responses following change-over to mixed species (porcine/bovine) insulins

Author

A. B. Kurtz, L. S. Gerlis, D. Cregan, M. I. Drury, R. Drury, and S. R. Bloom

Subjects
Adult, Blood Glucose, Male, medicine.medical_specialty, Adolescent, Swine, medicine.medical_treatment, Antibodies, Mixed species, Internal medicine, Animals, Humans, Insulin, Medicine, Pancreatic polypeptide, Proinsulin, Bovine insulin, biology, business.industry, General Medicine, Middle Aged, Regimen, Diabetes Mellitus, Type 1, Endocrinology, Antibody response, biology.protein, Cattle, Female, Antibody, business
Abstract

TWENTY-SEVEN insulin requiring diabetics, who had been treated with conventional non-purified insulins for at least four years, were transferred to a regimen of highly purified mixed species (porcine/bovine) insulin.

Published
1983
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23. Diabetic Education: A Physician's View-Who, What, Where, When and How

Author

M. I. Drury

Subjects
Physician-Patient Relations, medicine.medical_specialty, business.industry, Endocrinology, Diabetes and Metabolism, medicine.disease, Patient care, Self Care, Endocrinology, Patient Education as Topic, Family medicine, Diabetes mellitus, Diabetes Mellitus, Internal Medicine, medicine, Humans, Comprehensive Health Care, Medical emergency, business
Published
1984
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24. Renal clearance of pancreatic and salivary amylase relative to creatinine in patients with chronic renal insufficiency

Author

K F McGeeney, M D O'Donnell, J. B. Keogh, M. I. Drury, and T. B. Counihan

Subjects
Adult, Male, medicine.medical_specialty, Saliva, Pancreatic disease, Renal function, Kidney, Gastroenterology, chemistry.chemical_compound, Internal medicine, Diabetes Mellitus, medicine, Humans, Amylase, Pancreas, Aged, Creatinine, biology, business.industry, Middle Aged, medicine.disease, medicine.anatomical_structure, Endocrinology, chemistry, Amylases, biology.protein, Kidney Failure, Chronic, Pancreatitis, Female, business, Research Article
Abstract

Pancreatic and salivary amylase/creatinine clearance ratios in patients with various degrees of renal impairment were compared with those obtained for control subjects. In chronic renal insufficiency (mean GFR 30 ml/min +/- 15 SD; n = 13) the clearance ratios for pancreatic (mean 3.5 +/- 1.85 SD) and salivary (mean 2.3 +/- 1.3 SD) amylase were significantly higher (P less than 0.05) than those in controls. Corresponding control values (n = 26) were 2.64 +/- 0.86 (pancreatic) and 1.64 +/- 0.95 (salivary). Three patients showed values above the normal limit. In the diabetic group (mean GFR 41 ml/min +/- 22 SD; n = 10) salivary amylase/creatinine clearance ratios (mean 2.36 +/- 1.55 SD) were significantly higher than in controls (P less than 0.05). Three patients showed raised values. Pancreatic amylase clearance was raised in only one of these patients. Three patients with terminal disease (mean GFR 10 ml/min) showed markedly raised (two- to threefold) clearance ratios for both salivary and pancreatic amylase. Of a total of 26 patients, eight had increased total amylase/creatinine clearance ratios. Pancreatic amylase/creatinine clearance was increased in seven patients, while nine patients showed raised salivary amylase/creatinine ratios. Patients with raised clearance ratios did not have clinical evidence of pancreatitis. We suggest that, in the presence of impaired renal function, a high amylase/creatinine clearance ratio need not be indicative of pancreatic disease.

Published
1978
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25. Peripheral vascular disease—A radionuclide assessment

Author

B. M. Mooney, J. T. Ennis, T. P. Corrigan, D. J. Dowsett, and M. I. Drury

Subjects
Adult, Male, Contrast angiography, medicine.medical_specialty, Ischemia, Internal medicine, medicine, Humans, Vascular Diseases, Radionuclide Imaging, Ulcer, Aged, Radionuclide, Ventricular function, Vascular disease, business.industry, Arteries, General Medicine, Blood flow, Intermittent Claudication, Middle Aged, medicine.disease, Intermittent claudication, Peripheral, Cardiology, Female, Radiology, medicine.symptom, business
Abstract

Twenty-five patients presenting with intermittent claudication were studied with radionuclide arteriography to evaluate blood flow, capillary perfusion and left ventricular function. A comparison with the clinical presentation and contrast angiography showed that the radionuclide methods permitted a greater understanding of the physiological effects of ischaemia on the patient.

Published
1981
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26. HLA identity in juvenile onset diabetes

Author

G. Fitzgerald and M. I. Drury

Subjects
medicine.medical_specialty, business.industry, General Medicine, Human leukocyte antigen, Juvenile-Onset Diabetes, Diabetes Mellitus, Type 1, Juvenile onset, Endocrinology, HLA Antigens, Internal medicine, medicine, Humans, Sibling, Child, business
Abstract

Hla typing at the A and B locus was performed in 13 sibships of juvenile onset diabetics (JOD). Eight families had more than one diabetic sibling. HLA identity was significantly associated with the development of JOD. Fifty-five per cent of the HLA identical index siblings were diabetic. HLA-B8 was significantly increased in the diabetic sibs. There was a significant increase in HLA-A28 and decrease in HLA-B17 in the non-diabetic siblings compared with controls.

Published
1978
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27. Blood viscosity in umbilical cord blood from babies of diabetic mothers

Author

J. M. Stronge, R. Collins, Dermot MacDonald, M. I. Drury, and Michael E. Foley

Subjects
medicine.medical_specialty, Fetus, Pregnancy, Obstetrics, business.industry, Blood viscosity, Obstetrics and Gynecology, Hyperviscosity, medicine.disease, Umbilical cord, medicine.anatomical_structure, In utero, Cord blood, medicine, business, Diabetic control
Abstract

SummaryCompared with normal babies, whole blood viscosity and packed cell volume were significantly higher in cord blood from the newborn of diabetic mothers. The differences were most marked in macrosomic diabetic babies. Whole blood viscosity and packed cell volume are suggested as retrospective fetal markers of the quality of diabetic control in pregnancy. The concept of hyperviscosity in utero as a cause of intra-uterine death in infants of diabetic mothers is discussed

Published
1981
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30. Book reviews

Author

P. L. Chambers, Robert Carroll, Michael Solomons, G. F. Gearty, M. A. Powell, Brendan O’Brien, F. Kane, P. Quinn, F. J. Timoney, Blanche Weekes, Edward A. Martin, P. C. MacClancy, Desmond McGrath, Stanley T. McCollum, Alan Thompson, Allene IsaBel Scott, Eamonn De Valera, H. J. R. Henderson, D. E. Mellon, W. F. O’Dwyer, J. P. R. Rees, Victoria P. Coffey, James J. Fennelly, and M. I. Drury

Subjects
General Medicine
Published
1968
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31. Diabetes in Pregnancy

Author

M I Drury and B A Young

Subjects
Gynecology, medicine.medical_specialty, Pregnancy, Fetus, Obstetrics, business.industry, Vaginal delivery, medicine.disease, Infant mortality, Abortion rate, Diabetes mellitus, medicine, Maternal death, business, Diabetic ketosis
Abstract

A study of 300 pregnancies in 156 Irish diabetics is presented. Thirty per cent of the pregnancies were fifth or later, and the mean maternal age was thirty years. The abortion rate was 11 per cent, and the loss of viable infants was 10 per cent. There was no maternal death. Control of diabetes was strict, and this is reflected in the occurrence of hypoglycemic coma on twenty-one occasions. Diabetic ketosis occurred in twelve cases—all of whom were unbooked emergency admissions. The influence of these complications on fetal survival is contrasted. Pre-eclamptic toxemia and hydramnios in the mother, and respiratory-distress syndrome in the infant contributed heavily to infant loss. Of recent years the aim has been to deliver at thirtyeight weeks in uncomplicated cases—usually by the vaginal route. The cesarean section rate for the whole series was 22 per cent, and for primigravidae was 29 per cent. A plea is made for a more dynamic approach to vaginal delivery.

Published
1963
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32. Book reviews

Author

D. F. Cantwell, P. N. Meenan, Frederick S. Stewart, James G. Devlin, James J. Fennelly, J. B. Lyons, Michael Waldron, G. Everard Hewson, John P. Malone, J. G. Kirker, M. I. Drury, Michael F. Curtin, F. J. Henry, and Brendan O’Brien

Subjects
General Medicine
Published
1967
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33. Book reviews

Author

R. E. Steen, D. F. Cantwell, S. F. Cahalane, Robert Wilson, H. T. Barniville, W. D. Linehan, R. P. Kernan, M. L. Conalty, J. G. Kirker, A. B. Clery, J. McAuliffe Curtin, M. I. Drury, N. Jaswon, Gerard Brady, John Mowbray, Edward Tempany, C. S. Breathnach, R. S. W. Baker, Catherine Quinn, D. K. O’Donovan, Harold J. Browne, Keith M. Shaw, P. B. B. Gatenby, J. E. O’Connor, J. C. Cherry, G. Everard Hewson, David Lane, Joan Mullaney, and M. de Lourdes

Subjects
General Medicine
Published
1968
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35. Book reviews

Author

G. Everard Hewson, Sheamus Dundon, Kevin P. O’Flanagan, D. J. Stickler, Robert P. Towers, William MacGowan, M. I. Drury, John Mowpray, and J. J. Fennelly

Subjects
General Medicine
Published
1970
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36. Book reviews

Author

J. M. Irvine, W. F. O’Dwyek, Desmond McGrath, M. D. Hickey, Alan Thompson, D. A. A. Lane, Conor Ward, C. B. Robinson, Mervyn Abrahamson, and M. I. Drury

Subjects
General Medicine
Published
1963
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37. Book reviews

Author

L. B. Somerville-Large, R. B. Brenan, M. I. Drury, A. G. A. Heffernan, John Blake, Edward A. Martin, and Anthony Walsh

Subjects
General Medicine
Published
1966
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38. Book reviews

Author

Frank Kane, Risteárd Mulcahy, D. F. Cantwell, Geoffrey J. Bourke, David Mitchell, Dorothy Mitchell, J. B. Coakley, A. G. A. Heffernan, K. M. Allman, P. D. J. Holland, Alan Thompson, M. I. Drury, J. P. R. Rees, M. J. O’Shea, Michael F. Curtin, John P. Malone, David Lane, William Gavin, Mary O’Donnell, R. H. Micks, I. J. Temperley, and F. J. Henry

Subjects
General Medicine
Published
1967
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39. Book reviews

Author

D. M. Mitchell, L. B. Somerville-Labge, S. Desmond McGrath, R. S. W. Baker, M. L. Conalty, Brian Spencer, Joan Mullaney, M. I. Drury, J. G. Goodbody, L. B. Somerville-Large, P. C. McCrea, and F. D. McAuley

Subjects
General Medicine
Published
1964
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40. Book reviews

Author

J. B. Lyons, M. I. Drury, R. A. Q. O’meara, H. T. Barniville, C. S. Breathnach, G. P. Crookes, N. G. O’ Brien, P. G. Maddock, G. A. Connolly, J. J. Fennelly, M. P. Ashe, A. Walsh, and J. Lanigan

Subjects
General Medicine
Published
1971
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41. Book reviews

Author

John Blake, R. A. Q. O’Meara, R. P. Kernan, J. A. Mehigan, Barry O’Donnell, Patrick FitGerald, Brian Spencer, D. G. Weir, M. I. Drury, T. G. Wilson, and J. B. Healy

Subjects
General Medicine
Published
1967
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42. Book reviews

Author

C. S. Breathnach, S. F. Cahalane, C. A. Erskine, J. B. Lyons, Max J. Ryan, B. P. Kebnan, M. I. Drury, and Patrick A. Browne

Subjects
General Medicine
Published
1966
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43. Book reviews

Author

M. P. Ashe, J. B. Lyons, Anthony Walsh, J. C. Cherry, A. J. MacDonald, C. S. Breathnach, P. B. B. Gatenby, M. I. Drury, Peter McLean, G. D. Doyle, and null C. D.

Subjects
General Medicine
Published
1969
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44. Book reviews

Author

John P. Malone, Joseph Masterson, William MacGowan, Blanche Weekes, Austin T. Carthy, Alexander J. MacDonald, R. P. Kernan, J. B. Lyons, K. W. Taylor, M. I. Drury, and W. A. Ryan

Subjects
General Medicine
Published
1969
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45. Book reviews

Author

Robert Carroll, P. G. S. Beckett, J. B. Prendiville, Geoffrey J. Bourke, Miss K. Coonan, M. I. Drury, C. S. Breathnach, James ST. L. O'Dea, A. Walsh, B. M. Stokes, P. M. Guinan, Catherine A. Quinn, G. S. Smith, and J. Barnes

Subjects
General Medicine
Published
1972
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46. Book reviews

Author

A. P. Barry, P. J. Holland, M. I. Drury, and J. A. O’Connell

Subjects
General Medicine
Published
1961
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47. Book reviews

Author

Patrick Dwyer Joyce, Edward A. Martin, J. P. R. Rees, Michael Solomons, P. B. B. Gatenby, M. I. Drury, D. Hingerty, J. B. Lyons, T. Bradshaw, F. J. Henry, Douglas E. Mellon, C. A. Erskine, and Paul J. Cannon

Subjects
General Medicine
Published
1962
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48. Comparison of the folin/wu estimation of blood sugar with a glucose oxidase method for estimating glucose

Author

M I Drury and I Buckley

Subjects
Blood Glucose, medicine.medical_specialty, Chromatography, biology, Plant Extracts, business.industry, Blood sugar, General Medicine, Glucose Oxidase, Glucose, Endocrinology, Internal medicine, medicine, biology.protein, Humans, Regression Analysis, Glucose oxidase, Fasting blood sugar, business
Abstract

The Folin/Wu method for the estimation of blood sugar has been compared with an enzymatic estimation which is specific for β-D glucose. The principle and method for the enzymatic procedure are given. Fortyseven glucose tolerance tests analysed by both methods are presented. Twentyeight of these were normal ; the results are given in Table I. The mean fasting blood sugar by the enzymatic method was 74 mg% (range 53 to 94 mg%). The mean fasting blood sugar by the Folin/Wu method was 88 mg% (range 54-108 mg%). The results for the nineteen other tolerance tests are presented, fourteen diabetic curves and five indeterminate curves. The technique for each method is compared ; the cost of each method is given and the time required for each method of estimation is noted.

Published
1960
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49. Book reviews

Author

W. A. Boggust, Anthony Walsh, W. H. Verling, Éamon De Valeba, Brendan O’Brien, P. B. B. Gatenby, Patrick McCann, M. I. Drury, Michael O’Shea, Seamus O’Daly, and Robert P. Towers

Subjects
General Medicine
Published
1964
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