898 results on '"Laharie, David"'
Search Results
2. Long-term Outcome of Risankizumab in Crohn’s Disease: a Real-world GETAID Study
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Fumery, Mathurin, Caron, Benedicte, Hébuterne, Xavier, Altwegg, Romain, Roblin, Xavier, Stefanescu, Carmen, Meyer, Antoine, Nachury, Maria, Laharie, David, Le Berre, Catherine, Guillo, Lucas, Biron, Amélie, Caillo, Ludovic, Buisson, Anthony, Nancey, Stephane, Uzzan, Mathieu, Vuitton, Lucine, Gilletta, Cyrielle, Geyl, Sophie, Blain, Antoine, Kirchgesner, Julien, Ah-Soune, Philippe, Duveau, Nicolas, Vidon, Mathias, Abitbol, Vered, Paupard, Thierry, Tran-Minh, My-Linh, Defrance, Antoine, and Peyrin-Biroulet, Laurent
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- 2024
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3. Forecasted infliximab concentrations during induction predict time to remission and sustained disease control of inflammatory bowel disease
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Vermeire, Severine, Dubinsky, Marla C., Rabizadeh, Shervin, Panetta, John C, Spencer, Elisabeth A., Dreesen, Erwin, D'Haens, Geert, Dervieux, Thierry, and Laharie, David
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- 2024
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4. Correction: Efficacy of ustekinumab, vedolizumab, or a second anti-TNF agent after the failure of a first anti-TNF agent in patients with Crohn’s disease: a multicentre retrospective study
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Rayer, Cassandra, Nachury, Maria, Bourreille, Arnaud, Roblin, Xavier, Peyrin-Biroulet, Laurent, Viennot, Stephanie, Flamant, Mathurin, Laharie, David, Caron, Bénédicte, Dewitte, Marie, Siproudhis, Laurent, Fumery, Mathurin, and Bouguen, Guillaume
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- 2023
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5. Histological healing induced by tofacitinib in ulcerative colitis: A multicentre study
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Vieujean, Sophie, Laharie, David, Buisson, Anthony, Roblin, Xavier, Fumery, Mathurin, Nancey, Stephane, Wils, Pauline, Altwegg, Romain, Seidel, Laurence, Caron, Bénédicte, and Peyrin-Biroulet, Laurent
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- 2024
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6. Acute severe ulcerative colitis management: unanswered questions and latest insights
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Rivière, Pauline, Li Wai Suen, Christopher, Chaparro, María, De Cruz, Peter, Spinelli, Antonino, and Laharie, David
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- 2024
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7. Risk of Incident Cancer in Patients with Inflammatory Bowel Disease with Prior Breast Cancer: A Multicenter Cohort Study
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Bournet, Barbara, Denguir, Samira, Zerbib, Frank, Rivière, Pauline, Gagnière, Charlotte, Assaraf, Julie, Cadiot, Guillaume, Brixi, Hedia, Savoye, Guillaume, Yzet, Clara, Brazier, Franck, Peyrin-Biroulet, Laurent, Heinemann, Mellie, Vigneron, Nicolas, Coisnon, Marie, Amaro, Justine, Raad, Mira, Mailhat, Charlotte, Le Cosquer, Guillaume, Kirchgesner, Julien, Gilletta De Saint Joseph, Cyrielle, Seksik, Philippe, Amiot, Aurélien, Laharie, David, Nachury, Maria, Rouillon, Cléa, Abitbol, Vered, Nuzzo, Alexandre, Nancey, Stéphane, Fumery, Mathurin, Biron, Amélie, Richard, Nicolas, Altwegg, Romain, Moussata, Driffa, Caron, Benedicte, Vidon, Mathias, Reenaers, Catherine, Uzzan, Mathieu, Reimund, Jean-Marie, Serrero, Mélanie, Simon, Marion, Benezech, Alban, Goutorbe, Félix, Pelletier, Anne-Laure, Caillo, Ludovic, Vaysse, Charlotte, and Poullenot, Florian
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- 2024
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8. Obesity in adult patients with inflammatory bowel disease: Clinical features and impact on disability. A cross-sectional survey from the GETAID
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Amiot, Aurelien, Tadbiri, Sara, Gagniere, Charlotte, Tannoury, Jenny, Nachury, Maria, Pariente, Benjamin, Wils, Pauline, Bouhnik, Yoram, Stefanescu, Carmen, Treton, Xavier, Martins, Carole, Uzzan, Mathieu, Serrero, Melanie, Filippi, Jerome, Hébuterne, Xavier, Arab, Nadia, Cluzeau, Virginie, Roblin, Xavier, Tedesco, Emilie Del, Beaugerie, Laurent, Seksik, Philippe, Bourrier, Anne, Landmann, Cecilia, Kirchgesner, Julien, Sokol, Harry, Bouguen, Guillaume, Siproudhis, Laurent, DeWitte, Marie, Franchimont, Denis, Savoye, Guillaume, Buisson, Anthony, Louis, Edouard, Reenaers, Catherine, Nancey, Stephane, Boschetti, Gilles, Gay, Claire, Danion, Pauline, Flourié, Bernard, Abitbol, Vered, Malamut, Georgia, Reimund, Jean-Marie, Caron, Benedicte, DeWitt, Olivier, Vuitton, Lucine, Mathieu, Nicolas, Pestour, Sandie, Chateau, Thomas, Peyrin-Biroulet, Laurent, Zallot, Camille, Gilletta, Cyrielle, Allez, Matthieu, Gornet, Jean-Marc, Baudry, Clotilde, Viennot, Stephanie, Bourreille, Arnaud, Trang-Poisson, Caroline, Dib, Nina, Brixi, Hedi, Cadiot, Guillaume, Boualit, Medina, Painchart, Claire, Plastaras, Laurianne, Altwegg, Romain, Boivineau, Lucile, Fumery, Mathurin, Caillo, Ludovic, Laharie, David, Riviere, Pauline, Poullenot, Florian, Coffin, Benoit, Duboc, Henri, Nahon, Stephane, Tavernier, Noemie, Simon, Marion, Coulibaly, Baya, Amil, Morgane, Nicolas, Duveau, Khater, Sherine, Kaassis, Mehdi, Goutorbe, Felix, Moussata, Driffa, Picon, Laurence, Bacha, Rose Al, DeWit, Olivier, and Berre, Catherine Le
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- 2023
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9. Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study
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Abrahamovych, Orest, Afanasieva, Halyna, Aitova, Lilia, Altintas, Engin, Altwegg, Romain, Andreev, Pavel, Aomatsu, Kazuki, Augustyn, Monika, Balestrieri, Paola, Begun, Jakob, Brunatto, Luciana, Bulgheroni, Diego, Bunkova, Elena, Cabello, Mercedes, Cao, Qian, Caprioli, Flavio, Cerqueira, Rute, Chen, Baili, Chen, Chou-Chen, Chen, Chou-Pin, Chiu, Cheng-Tang, Choi, Chang Hwan, Cicala, Michele, Datsenko, Olena, Dewint, Pieter, Domenech, Eugeni, Dutré, Joris, Duvall, George, Fernandez, Juan, Filip, Rafal, Fogel, Ronald, Fowler, Sharyle, Fujii, Toshimitsu, Fukata, Masayuki, Furumoto, Yohei, Gasbarrini, Antonio, Gawdis-Wojnarska, Beata, Gilletta, Cyrielle, Gionchetti, Paolo, Goldin, Eran, Golovchenko, Oleksandr, Gonciarz, Maciej, Gonen, Can, Segura, Gaston Gonzalez, Gridnyev, Oleksii, Gyokeres, Tibor, Hébuterne, Xavier, Hedin, Charlotte, Hellström, Per, Hilmi, Ida Normiha, Horný, Ivo, Horvat, Gyula, Hoshi, Namiko, Hrdlicka, Ludek, Ishihara, Shunji, Ivanishyn, Olha, Jang, Byung Ik, Junior, Odery, Kagaya, Takashi, Kanmura, Shuji, Karakina, Marina, Katsuhiko, Nakai, Kierkus, Jaroslaw, Kim, Hyo Jong, Kim, Tae-Oh, Kim, Young-Ho, Kiss, Gyula G., Klaus, Jochen, Kleczkowski, Dariusz, Klopocka, Maria, Kobayashi, Taku, Kobielusz-Gembala, Iwona, Koo, Ja Seol, Kopon, Adam, Kravchenko, Tetiana, Kudo, Masatoshi, Kwon, Kwang An, Lago, Paula, Laharie, David, Lawrance, Ian, Leszczyszyn, Jaroslaw, Li, Yan, Lukas, Milan, Maaser, Christian, Maemoto, Atsuo, Marusawa, Hiroyuki, McBride, Matthew, Mendu, Shoba, Miheller, Pal, Miyabayashi, Hideharu, Mohl, Wolfgang, Moore, Gregory, Motoya, Satoshi, Murali, Narayanachar, Naem, Mohammed, Nakajima, Koichi, Nakamoto, Yasunari, Nancey, Stéphane, Neto, Joaquim, Onizawa, Michio, Ono, Yohei, Osada, Taro, Osipenko, Marina, Owczarek, Danuta, Patel, Bhaktasharan, Patel, Kamal, Petrova, Elina, Poroshina, Elena, Portela, Francisco, Prystupa, Lyudmyla, Rivero, Monserrat, Roblin, Xavier, Romatowski, Jacek, Rydzewska, Grazyna, Saibeni, Simone, Sakuraba, Hirotake, Samaan, Mark, Schultz, Michael, Schulze, Joerg, Sedghi, Shahriar, Seidler, Ursula, Shin, Sung Jae, Stanislavchuk, Mykola, Stokesberry, David, Suzuki, Takayoshi, Taguchi, Hiroki, Tankova, Lyudmila, Thin, Lena, Tkachev, Alexander, Torrealba, Leyanira, Tsarynna, Nataliia, Tulassay, Zsolt, Ueo, Tetsuya, Valuyskikh, Ekaterina, Vasilevskaya, Olga, Viamonte, Manuel, Wei, Shu-Chen, Weisshof, Roni, Wojcik, Katarzyna, Ye, Byong Duk, Yen, Hsu-Heng, Yoon, Hyuk, Yoshida, Kosuke, Yurkiv, Andriy, Zaha, Osamu, Zhan, Qiang, Peyrin-Biroulet, Laurent, Allegretti, Jessica R., Rubin, David T., Bressler, Brian, Germinaro, Matthew, Huang, Kuan-Hsiang (Gary), Shipitofsky, Nicole, Zhang, Hongyan, Wilson, Rebbecca, Han, Chenglong, Feagan, Brian G., Sandborn, William J., Panés, Julian, Hisamatsu, Tadakazu, Lichtenstein, Gary R., Sands, Bruce E., and Dignass, Axel
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- 2023
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10. Time trend in surgical indications and outcomes in ulcerative colitis—A two decades in-depth retrospective analysis
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Le Cosquer, Guillaume, Capirchio, Lena, Rivière, Pauline, Denis, Marie Armelle, Poullenot, Florian, Remue, Christophe, Zerbib, Frank, Leonard, Daniel, Célérier, Bertrand, Kartheuser, Alex, Laharie, David, and Dewit, Olivier
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- 2023
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11. Prevalence of and Factors Associated With Extraintestinal Manifestations and Their Remission in Inflammatory Bowel Disease: The EXTRA-Intestinal Manifestation Prospective Study From the Groupe dʼEtude Thérapeutique des Affections Inflammatoires du Tube Digestif
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Guillo, Lucas, Savoye, Guillaume, Amiot, Aurélien, Gilletta, Cyrielle, Nachury, Maria, Dib, Nina, Bourreille, Arnaud, Roblin, Xavier, Caillo, Ludovic, Allez, Matthieu, Picon, Laurence, Hébuterne, Xavier, Seksik, Philippe, Chupin, Antoine, Buisson, Anthony, Brixi, Hédia, Altwegg, Romain, Simon, Marion, Amil, Morgane, Laharie, David, Bouguen, Guillaume, Serrero, Mélanie, Elgharabawy, Yasmine, and Peyrin-Biroulet, Laurent
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- 2023
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12. Iron Deficiency in Patients with Inflammatory Bowel Diseases: A Prospective Multicenter Cross-Sectional Study
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Peyrin-Biroulet, Laurent, Bouguen, Guillaume, Laharie, David, Pellet, Gauthier, Savoye, Guillaume, Gilletta, Cyrielle, Michiels, Christophe, Buisson, Anthony, Fumery, Mathurin, Trochu, Jean-Noël, and Cacoub, Patrice
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- 2022
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13. Efficacy of ustekinumab, vedolizumab, or a second anti-TNF agent after the failure of a first anti-TNF agent in patients with Crohn’s disease: a multicentre retrospective study
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Rayer Cassandra, Maria Nachury, Bourreille Arnaud, Roblin Xavier, Peyrin-Biroulet Laurent, Viennot Stephanie, Flamant Mathurin, Laharie David, Caron Bénédicte, Dewitte Marie, Siproudhis Laurent, Fumery Mathurin, and Bouguen Guillaume
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Crohn’s disease ,Anti-TNF ,Vedolizumab ,Ustekinumab ,Treatment strategy ,Second line ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Abstract Background No study has performed a face-to-face comparison of biologics after the failure of the first anti-TNF agent in patients with Crohn’s disease (CD). The aim of the study was to compare the efficacy of biologics in this setting. Methods Patients with CD who were refractory to a first anti-TNF agent, and treated with ustekinumab (UST), vedolizumab (VDZ), or a second anti-TNF drug as a second-line biological agent at 10 French tertiary centres from 2013 to 2019 were retrospectively included in this study. Results Among the 203 patients included, 90 (44%) received UST, 42 (21%) received VDZ and 71 (35%) received a second anti-TNF agent. The first anti-TNF agent was discontinued due to a primary nonresponse in 42 (21%) patients. At weeks 14–24, the rates of steroid-free remission were similar between the UST, VDZ and second anti-TNF groups (29%, 38% and 44%, respectively, p = 0.15). With a mean follow-up of 118 weeks, drug survival was shorter for patients who received ustekinumab treatment (p = 0.001). In the case of trough level less than 5 µg/ml, patients treated with a second anti-TNF agent had a higher postinduction remission rate (p = 0.002), and drug survival (p = 0.0005). No other relevant factors were associated with treatment efficacy, including trough levels greater than 5 µg/ml. Conclusions VDZ, UST and a second anti-TNF agent exhibit similar efficacy in the short term, as second-biological line treatment in patients with CD who are refractory to a first anti-TNF agent, but shorter drug maintenance is observed for patients treated with UST.
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- 2022
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14. Risk of SARS-CoV-2 infection in healthcare workers with inflammatory bowel disease: a case-control study
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Amiot, Aurelien, Bourrier, Anne, Gornet, Jean-Marc, Dewit, Olivier, Nancey, Stephane, Altwegg, Romain, Abitbol, Vered, Laharie, David, Reenaers, Catherine, Gagnière, Charlotte, Buisson, Anthony, Nachury, Maria, Viennot, Stephanie, Vuitton, Lucine, Stefanescu, Carmen, Marteau, Philippe, Bouguen, Guillaume, and Seksik, Philippe
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- 2023
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15. Withdrawal of infliximab or concomitant immunosuppressant therapy in patients with Crohn's disease on combination therapy (SPARE): a multicentre, open-label, randomised controlled trial
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Andrews, Jane, Sparrow, Miles, Leong, Rupert, Connor, Susan, Radforth-Smith, Graham, De Cruz, Peter, Preiss, Jan, Stallmach, Andrea, Liceni, Thomas, Grip, Olaf, Halfvarson, Jonas, Durai, Dharmaraj, Cummings, Fraser, Seilinger, Christian, Parkes, Miles, Lindsay, James, Lambrecht, Guy, Van Hootegem, Philippe, Rahier, Jean-François, Dewitte, Marie, Hebuterne, Xavier, Chanteloup, Elise, Altwegg, Romain, Nancey, Stephane, Bouguen, Guillaume, Pineton de Chambrun, Guillaume, Poullenot, Floriant, Roblin, Xavier, Louis, Edouard, Resche-Rigon, Matthieu, Laharie, David, Satsangi, Jack, Ding, Nik, Siegmund, Britta, D'Haens, Geert, Picon, Laurence, Bossuyt, Peter, Vuitton, Lucine, Irving, Peter, Viennot, Stephanie, Lamb, Christopher A, Pollok, Richard, Baert, Filip, Nachury, Maria, Fumery, Mathurin, Gilletta, Cyrielle, Almer, Sven, Ben-Horin, Shomron, Bouhnik, Yoram, Colombel, Jean-Frederic, and Hertervig, Erik
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- 2023
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16. I-CARE, a European Prospective Cohort Study Assessing Safety and Effectiveness of Biologics in Inflammatory Bowel Disease
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Gornet, Jean-Marc, Beaugerie, Laurent, Shaji, Sebastian, Peyrin-Biroulet, Laurent, Reimund, Jean-Marie, Hebuterne, Xavier, Amiot, Aurélien, Armelao, Franco, Blanc, Pierre, Papi, Claudio, De Chambrun, Guillaume Pineton, Roblin, Xavier, Chu, Karmiris, Konstantinos, Shariq, Sohail, Viazis, Nikolaos, Limdi, Jimmy, Eder H, Piotr, Michalopoulos, Georgios, Bell, Andrew, Biancone, Livia, Dewitte, Marie, Mazhar, Zia, Franchimont, Denis, Nancey, Stephane, Macaigne, Gilles, Principi, Maria Beatrice, Fumery, Mathurin, Parkes, Gareth, Valats, Jean-Christophe, Doherty, Glen, Bouguen, Guillaume, Molnar, Tamás, Tsai, Hersin, Gangi, Mohsin, Pedersen, Natalia, Heluwaert, Frédéric, Shenderey, Richard, Zeissig, Sebastian, Butterworth, Jeffrey, Castiglione, Fabiana, Corless, Lynsey, Zallot, Camille, Baert, Filip, Singh, Salil, Sonwalkar, Sunil, Clayton, Elizabeth, Rahier, Jean-François, Vani, Deven, Bellaiche, Guy, De Vos, Martine, Kirchgesner, Julien, Kopylov, Uri, Lobaton, Triana, Locher, Christophe, Mantzaris, Gerassimos, Abouda, George, Smith, Katie, Sprakes, Michael, Theodoropoulou, Angeliki, Wesley, Emma, Bonnet, Joëlle, Elphick, David, Gilletta, Cyrielle, Gordon, John, Laharie, David, Nakad, Antoine, Orlando, Ambrogio, Dubois, Patrick, Hasselblatt, Peter, Michiels, Christophe, Preston, Cathryn, Staicu, Anca, Vuitton, Lucine, Kaassis, Mehdi, Speight, Ally, Ghosh, Deb, Löwenberg, Mark, Mathieu, Nicolas, Pelletier, Anne-Laure, Phillips, Anne, Magro, Fernando, Altwegg, Romain, Avni, Irit, biron, Landy, Jonathon, Nachury, Maria, Shenoy, Achuth, Trang, Caroline, Abitbol, Vered, Bamias, Georgios, Farkas, Klaudia, Maaser, Christian, Shitrit, Ariella, Siegmund, Britta, Filippi, Jérôme, O'morain, Colm, Yanai, Henit, Costes, Laurent, Hobday, David, Szepes, Zoltán, Calabrese, Emma, Dallal, Helen, Fung, Michael, Ramadas, Arvind, Baburajan, Bijay, Koss, Konrad, Barberis, Christophe, Buisson, Anthony, Amil, Morgane, Balestrieri, Paola, Johnson, Matthew, Tzouvala, Maria, Viennot, Stéphanie, Nagy, Ferenc, Thompson, Nick, Alric, Laurent, Samuel, Sunil, Bourrier, Anne, Chanteloup, Elise, Del Tedesco, Emilie, Harbord, Marcus, Lobo, Alan, Myers, Sally, Pollok, Richard, Ahmad, Tariq, Chaudhary, Rakesh, Karakoidas, Christos, Soliman, Ashraf, Stefanescu, Carmen, Theocharis, Georgios, Branden, Stijn Vanden, Beltran, Belén, Bouhnik, Yoram, Bourreille, Arnaud, Branco, Joana, Colleypriest, Ben, Eliakim, Rami, Knight, Paul, O'toole, Aoibhlinn, Robles, Virgina, Triantafyllou, Konstantinos, Bosca, Marta Maia, Lambrecht, Guy, Mosquera, Lucia Marquez, Panter, Simon, Pappa, Aikaterini, Simon, Marion, Sivaji, Ganesh, Bellanger, Christophe, Belle, Arthur, Borruel, Natalia, Egan, Laurence, Peeters, Harald, Sharpstone, Daniel, Arasaradnam, Ramesh, Benitez, José Manuel, Dahlerup, Jens Frederik, Giouleme, Olga, Gisbert, Javier P., Helwig, Ulf, Minguez, Miguel, Tsironi, Eftychia, Variola, Angela, Allen, Patrick, Boivineau, Lucille, Cole, Andy, Dib, Nina, Gomollon, Fernando, Johnston, Richard, Katsanos, Konstantinos, Kennedy, Nick, Kiszka-Kanowitz, Marianne, Marin-Jimenez, Ignacio, Miheller, Pál, Nos, Pilar, Saraj, Othman, Vinter-Jensen, Lars, Zittan, Eran, Baudry, Clotilde, Calvet, Xavier, Cazelles-Boudier, Marie-Christine, Coenegrachts, Jean-Louis, Cullen, Garret, Daperno, Marco, Dhar, Anjan, Gerard, Romain, Jensen, Nanna, Maharshak, Nitsan, Mcalindon, Mark, Mcloughlin, Simon, Parkes, Miles, Patel, Kamal, Peixoto, Armando, Polymeros, Dimitrios, Portela, Francisco, Rocca, Rodolfo, Seksik, Philippe, Subramanian, Sreedhar, Tennenbaum, Ruth, Atreya, Raja, Bachmann, Oliver, Berger, Arthur, Bor, Renáta, Buckley, Maire, Carpio, Daniel, Chaparro, María, Costa, Francesco, Domenech, Eugeni, Esteve, Maria, Foley, Stephen, Guardiola, Jordi, Koutroubakis, Ioannis, Kuehbacher, Tanja, Landman, Cécilia, Lavagna, Alessandro, Manceñido, Noemí, Mañosa, Míriam, Martín-Arranz, Maria Dolores, Plastaras, Laurianne, Scribano, Maria Lia, Sengupta, Subhasish, Teich, Nils, Tran-Minh, My-Linh, Zampeli, Evanthia, Amininejad, Leila, Arroyo, Teresa, Attar, Alain, Backman, Ann-Sofie, Bálint, Anita, Beckly, John, Ben Horin, Shomron, Bernardo, Sónia, Caillo, Ludovic, Caron, Bénédicte, Shanika de Silva, María, FábiáN, Anna, Fiorino, Gionata, Gutierrez, Ana, Lahat, Adi, Masmoudi, Mohamed, Mendolaro, Marco, Muls, Vinciane, Poullenot, Florian, Probert, Christopher, Reenaers, Catherine, Rutka, Mariann, Sarwari, Zaman, Sayer, Joanne, Sicilia, Beatriz, Sousa, Helena, van Kemseke, Catherine, Zabana, Yamile, Astegiano, Marco, Banim, Paul, Bettenworth, Dominik, Boualit, Médina, Brodersen, Jacob Broder, Christidou, Angeliki, Cooney, Rachel, Pinto, João Cortez, Cravo, Portugal Marília, Cremer, Anneline, Danese, Silvio, di Sabatino, Antonio, Fallingborg, Jan, Ferronato, Antonio, Planella, Esther Garcia, Gupta, Sanjay, Halfvarson, Jonas, Israeli, Eran, Kestenbaum, Samantha, Larsen, Lone, Macken, Elisabeth, Mathou, Nicoletta, Milassin, Ágnes, Pofelski, Joanna, Ricci, Chiara, Rodriguez-Moranta, Francisco, Schmidt-Lauber, Martin, Shaw, Ian, Soares, Marta, Soliman, Heithem, Triantos, Christos, Zografos, Konstantinos, Agrawal, Anurag, Armuzzi, Alessandro, Aubourg, Alexandre, Acosta, Manuel Barreiro-de, Barrio, Jesús, Bergemalm, Daniel, Bermejo, Fernando, Bodini, Giorgia, Bohr, Johan, Bossuyt, Peter, Christodoulou, Dimitrios, Claessens, Christophe, Collins, Paul, de Francisco, Ruth, Garcia, Santiago, Georgopoulos, Sotirios, Goutorbe, Felix, Kalantzis, Chrisostomos, Kourikou, Anastasia, Mace, Vincent, Malamut, Georgia, Ministro, Paula, Larmurier, Isabelle Nion, Ricart, Elena, Serrero, Mélanie, Sheridan, Juliette, Weimers, Petra, Andersen, Vibeke, Arroja, Bruno, Bokemeyer, Bernd, Bujanda, Luis, Degand, Thibault, Eriksson, Carl, Garceau, Cécile, Glerup, Henning, Goren, Idan, Jackson, Lucina, Koch, Stéphane, Mesonero, Francisco, Ordas, Ingrid, Riviere, Pauline, Saibeni, Simone, Soares, João, Tavernier, Noémie, Theede, Klaus, Ungar, Bella, Bästlein, Elke, Gasbarrini, Antonio, Protopapas, Andreas, Reindl, Wolfgang, Bossa, Fabrizio, Hart, Ailsa, Heil, Franz-Josef, O'Connor, Anthony, Oldenburg, Bas, Pastorelli, Luca, Stephen patchett, Ramakrishnan, Subramaniam, de Caestecker, John, Echarri, Ana, Kevans, David, Büning, Jürgen, Coelho, Rosa, Jansen, Jeroen, Koslowski, Benjamin, Wells, Christopher, Ceballos, Daniel, König, Ingrid, Padmanabhan, Hari, Patani, Timi, Qureshi, Raheel, Zagorowicz, Edyta, Allez, Matthieu, Archavlis, Emmanouil, Bonnet, Delphine, Guidi, Luisa, Mcnamara, Deirdre, Vernia, Piero, Weidenhiller, Michael, Alon, Lang, Boysen, Trine, Delattre, Charlotte, Farrell, Richard, Krüger, Rolf-Achim, Paupard, Thierry, Vind, Ida, Caprioli, Flavio, Gancho, Vladimir, Quentin, Vincent, Avidan, Benjamin, D’Haens, Geert, Mccarthy, Jane, Snook, Jonathon, Soufleris, Konstantinos, Zerbib, Frank, Carter, Dan, Depla, Annekatrien, Eisenbach, Thomas, Fries, Walter, Grammatikos, Nikolaos, Ilegems, Saskia, Lopez-Sanroman, Antonio, Moreau, Jacques, Riegler, Gabriele, Rietdijk, Svend, Rocha, Marta, Rosa, Isabelle, Ryan, Barbara, Yeremenko, Yelena, Boruchowicz, Arnaud, Damião, Filipe, Laoudi, Foteini, Lügering, Andreas, Macarri, Giampiero, Thomopoulos, Konstantinos, Barros, Luísa, Blixt, Thomas, Garros, Aurélien, Khorrami, Sam, Sokol, Harry, Sturm, Andreas, Livovsky, Dan, Maul, Jochen, Miks, Heinrich, Papadopoulos, Vasileios, Schmidt, Carsten, Snir, Yifat, Svenningsen, Lise, Ahmed, Wafaa, Broitman, Yelena, Cuillerier, Emmanuel, Kant, Prashant, Leyden, Jan, Lichtenstein, Lev, Lopes, Susana, Martineau, Chloé, Mulcahy, Hugh, Schweitzer, Axel, Van Schaik, Fiona, Banai, Hagar, Danion, Pauline, Dulery, Charlotte, Fidder, Herma, Gay, Claire, Hagege, Hervé, Harnois, Florence, Jørgensen, Søren Peter, Müller-Ziehm, Jens, Oikonomou, Michail, Palmela, Carolina, Schulze/Röske, Jörg, Smith, Mark, Thurm, Tamar, Bresso, Francesca, Brixi, Hedia, Jones, John, Macmathuna, Padraig, Painchart, Claire, Ron, Yulia, Vester-Andersen, Marianne, Alexandrino, Gonçalo, Börner, Norbert, Cardoso, Mariana, Chagas, Cristina, Dignaß, Axel, Dotan, Iris, Hedin, Charlotte, Karatzas, Pantelis, Kasapidis, Panagiotis, Palatka, Károly, Sakizlis, Georgios, Wilson, Ana, Bosanko, Nick, Caldeira, Paulo, Gagniere, Charlotte, Libier, Louise, Meunier, Camille, Moog, Gero, Pasquion, Audrey, Pica, Roberta, Akbar, Ayesha, Arab, Nadia, Cadiot, Guillaume, Carvalho, João, Charpignon, Claire, Fellermann, Laus, Fishman, Sigal, Fraser, Gerald, Gluck, Nathan, Hoesl, Mark, Kierkus, Jarosław, Klopocka, Maria, Arranz, Eduardo Martin, Menchen, Luis, Nikolaus, Susanna, Petrache, Anca, Ponsioen, Cyriel, Riestra, Sabino, Robledo, Pilar, Rodriguez, Cristina, Samer, Misheal, Tischer, Matthias, Wypych, Joanna, Baudon, Julien, Bezzio, Cristina, Boschetti, Gilles, Burisch, Johan, Creed, Tom, Demarzo, Maria Giulia, Festa, Stefano, Figueroa, Andrés, Julsgaard, Mette, Navarro, Pablo, Perez-Galindo, Pablo, Rouillon, Cléa, Sablich, Emanuele, Tosca, Joan, Vidon, Mathias, Vidon, Marine, Vitte, René-Louis, Wampach, Anne, Baumann, Cédric, Urmes, Isabelle Clerc, Rousseau, Hélène, Borie, Marc, Uzzan, Mathieu, Chatten, Kelly, Peter, Rimmer, Tariq, Iqbal, Cossignani, Marta, Cañete, Fiorella, Holvoet, Tom, Krasz, Susanne, Dias, Sandra, Abalia, Hadas, Abaza, Aziza, Abramovich, Gal, Ackzell, Ingrid, Adams, Carol, Addleton, Catherine, Alfambra, Erika, Algaba, Alicia, Allcock, Clare, Allison, Joanna, Amouriaux, Karine, Anderson, Julie, Anderson, Emma, Appelmans, Saskia, Armstrong, Lisa, Atkins, Stacey, Attaran-Bandarabadi, Masoumeh, Bailey, Yvonne, Bardot, Stephanie, Beck, Natasha, Bennett, Lillie, Bergfeld, Jonathan Phil, Berkane, Ramdane, Boey, Hanne, Bowlas, Louise, Bradley-Potts, Joanne, Brear, Tracy, Bretlander-Peters, Nicole, Brown, Ellen, Brown, Johanna, Buckingham, Elizabeth, Buellens, Katrien, Bull, Rhian, Burke, Maura, Burns, Leighanne, Burton, Julie, Bwalya, Agness, Cabanas, Karine, Callaghan, Muriel, Camou, Océane, Campbell, Debbie, Capoferro, Elvira, Carnahan, Mandy, Carnio, Cornelia, Carter, Anne, Clack, Concetta Casali, Chedouba, Leïla, Cipriano, Bessie, Claeys, Sophie, Closset, Manon, Coban, Dilek, Cococcia, Sara, Coe, Carolann, Cole, Helen, Collet, Emilie, Collins, Kayleigh, Combes, Isabelle, Connor, Emma, Constantin, Kathryn, Cooke, Susan, Cornet, Nathanaëlle, Corrihons, Estelle, Corsino, Pilar, Cortaville, Rosie, Cotterill, Donna, Cowton, Amanda, Cox, Harriet, Cripps, Viktoria, Crowder, Amanda, Cukier, Tzufit, Daniel, Amelia, Dawe, Chris, de Haan, Jose, Croix, Rosanna de la, Dejonckheere, Evva, Villanegro, Juan Delare, Delaval, Guillaume, Delliponti, Mariangela, Delommez, Aude, Detry, Emilie, Dhanaratne, Melanie, Galan, Laura Diez, Dodel, Marie, Dooks, Emma, Du Cheyron, Joseph, Duane, Linda, Vulgo Cochran, Jennifer Dulling, Dyer, Simona, Dymond, Harvey, Ekblad, Charlotte, Elliott, Kerry, Emmerson, Ingrid, Eugene-Jolchine, Irène, Fleming, Lorna, Fletcher, Eve, Ford, Sarah, Forshaw, Greg, Foulds, Angela, Francois, Caroline, Fuge, Nicole, Gafni, Gal, Ganon, Miri, Nuñez, Olga Garcia, Ramirez, Laura Garcia, Gelder, Sophie, Gettkowski, Raimonda, Gilardi, Daniela, Giuffrida, Paolo, Gobert, Vincent, Godden, Jo, Godwin, Nuala, Goulden, Kay, Graham, Sharon, Green, Charlotte, Green, Marie, Gueye, Aboubakar, Guler, Tuba, Gustavsson, Ida, Hadjisavvas, Helena, Hammonds, Fiona, Hantzi, Christina, Hauke, Marion, Haydock, Julie, Hayes, Orla, Nislev, Lizette Helbo, Hochstodter, Jessica, Hogg, Ashleigh, Hölbing, Manuela, Holland, Maureen, Holsbergen, Maartje, Howard, Linda, Hoyda, Aviya, Hull, Robert, Irish, Jane, Jackson, Wendy, Janssen, Wendy, Jeffrey, Lesley, Jourdan, Sofia, Jutrowska, Izabela, Kaniel, Chava, Karezos, Theofilos, Kelly, Niamh, Kelly, Jessica, Kennedy, Mary, Kennedy, Una, Kibaru, Joyce, Kirkman, Gemma, Klaproth, Janine, Kneese, Corinna, Koch, Andrea, Kokke, Kathleen, Koppelow, Martha, Krause, Sabine, Krauspe, Sabine, Kwakkenbos, Petra, Labarile, Nunzia, Lang, Hannah, Lassailly, Marianne, Leconte, Martine, Lepczynski, Linda, Levell, Emma, Levhar, Nina, Lindhort, Kerstin, Lisle, Jessica, Cauce, Beatriz Lopez, Lorenz, Gabriele, Lovati, Ambra, Lowry, Tracey, Lund, Margareta, Vorderbrügge, Anne Lutz, Maansson, Suzanne, Madapathage, Videsheka, Cheviakoff, Maelys, Magness, Alison, Manley, Orla, Manyoni, Catherine, Marg, Ingke, Marra, Antonella, Martins, Carole, Massella, Arianna, Mathias, Aurore, Mervyn, Danielle, Minsart, Charlotte, Mitchell, Sally, Monks, Kathleen, Montero, Mélanie, Moore, Alson, Moser, Maren, Moss, Alison, Mullen, Angela, Murciano, M. Francisca, Naylor, Deanna, Nehus, Ansgar, Nicholson, Anne, Nöding, Sarah, Nolan, Sinead, Nörenberg, Janet, Northcott, Clare, O'Connell, Jim, O’Kelly, Alison, Orbach-Zingboim, Noam, Orobitg, Judit, Otieno, Charlene, Owen, Charlotte, Patch, Sarah, Pauker, Maor, Pauli, Renate, Pearson, Harriet, Peggy, Falgon, Petit, Séverine, Petrissans, Christine, Piergallini, Simona, Pippard, Lucy, Pitt, Laura, Pócsik, Gabriella, Poher, Yoann, Pomes, Chloé, Pritchard, Lucy, Puchades, Laura, Quaid, Sheena, Rana, Aleem, Raynard, Dana, Reilly, Mykla, Reinert, Sonja, Reinknecht, Manuela, Renner, Baerbel, Reynolds, Rob, Rizzuto, Giulia, Robinson, Matthew, Robrechts, Joke, Rodriguez, Eva M., Rosenblum, Efrat, Russel, Tamlyn, Sadare, Ibiyemi, Salama, Noa, Schakel, Toos, Schauer, Anja, Schiavoni, Elisa, Shaw, Caroline, Shelton, Sarah, Sicart, Virginie, Siouville, Elodie, Smith, Orla, Soude, Théo, Stephenson, Sophie, Stephenson, Elaine, Steppe, Marjan, Sterkx, An, Stickley, Jo, Sugrue, Kathleen, Swietec, Natalia, Tasiaux, Charlotte, Thamu, Bhavneet, Thomas, Susane, Tobi, Ogwa, Touabi, Kahina, Tovi, Shifra, Tregonning, Julie, Turchini, Laura, Unkhoff, Julia, Unruh, Olesya, Uzun, Nurcan, Van Aert, Frauke, Bergh, Sandrine Vanden, Vandenbroucke, Louise, Vansteenkiste, Laura, Vardit, Shay, Vergriete, Valentin, Walker, Elaine, Warner, Eleanor, Watchorn, Olivia, Watson, Ekaterina, Wauthier, Marie-Claire, Weetman, Belgium Maria, Weston, Margaret, West-Petroschka, Wiebke, Wienecke, Susann, Wierling, Kerstin, Wiestler, Miriam, Wilcox, Rebecca, Wilhelmsen, Elva, Williams, Angharad, Williamson, Georgina, Wilson, Deborah, Wistance, Kate, Wortmann, Nicolas, Wurie, Subie, Yadgar, Karin, Young, Gail, Young, Megan, Aucouturier, Julien, Bertin, Marie- Jo, Bougrine, Hasnae, Coisnon, Marie, Defrance, Antoine, Gutierrez, Kati, Harouz, Amel, Jerber, Laure, Khlifi, Aida, Kirati, Amina, Liworo, Nasaladjine, Logoltat, Maude, Mailhat, Charlotte, M'Bayi, Chancely, Medane, Yasmina, Merkhoufa, Dalal, Elhad, Saouda Mohamed, Monthe, Bertille, Moyon, Fanny, Rabiega, Pascaline, Sekela, Jennifer, Thilloy, Charlotte, Hamamouche, Naima, Partisotti, Frederic, Blandin, Patrick, Mokhtari, Hocine, Coutard, Laure, and Doherty, Glen A.
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- 2023
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17. Prevalence of Self-Reported Venous Thromboembolism and Cardiovascular Risk Factors in Patients with Ulcerative Colitis: The GETAID FOCUS Study
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Guillo, Lucas, Amiot, Aurélien, Serrero, Mélanie, Altwegg, Romain, Roblin, Xavier, Atanasiu, Calina, Buisson, Anthony, Le Berre, Catherine, Reenaers, Catherine, Gornet, Jean-Marc, Laharie, David, Abitbol, Vered, Biron, Amélie, Caron, Bénédicte, Nancey, Stéphane, Chupin, Antoine, Blain, Antoine, Vuitton, Lucine, Caillo, Ludovic, Kirchgesner, Julien, Nachury, Maria, and Peyrin-Biroulet, Laurent
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- 2022
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18. Etrolizumab as induction and maintenance therapy in patients with moderately to severely active Crohn's disease (BERGAMOT): a randomised, placebo-controlled, double-blind, phase 3 trial
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Sandborn, William J, Panés, Julian, Danese, Silvio, Sharafali, Zaineb, Hassanali, Azra, Jacob-Moffatt, Rhian, Eden, Christopher, Daperno, Marco, Valentine, John F, Laharie, David, Baía, Carolina, Atreya, Raja, Panaccione, Remo, Rydzewska, Grazyna, Aguilar, Humberto, and Vermeire, Séverine
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- 2023
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19. Management of immune checkpoint inhibitor in patients with cancer and pre-existing inflammatory bowel disease: Recommendations from the GETAID
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Peyrin-Biroulet, Laurent, Laharie, David, Bourreille, Arnaud, Vuitton, Lucine, Bouguen, Guillaume, Abitbol, Vered, Amiot, Aurelien, Biron, Amelie, Bourrier, Anne, Caillo, Ludovic, Fumery, Mathurin, Gilletta, Cyrielle, Plastaras, Laurianne, Serrero, Melanie, Simon, Marion, Viennot, Stephanie, Seksik, Philippe, Attar, Alain, Buisson, Anthony, Caron, Benedicte, Charkaoui, Maeva, Gornet, Jean-Marc, Guillo, Lucas, Berre, Catherine Le, Louis, Edouard, Malamut, Georgia, Mathieu, Nicolas, Nachury, Maria, Nancey, Stephane, Paul, Stephane, Reenaers, Catherine, Treton, Xavier, Uzzan, Mathieu, Wils, Pauline, and Poullenot, Florian
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- 2022
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20. Steroid-Free Deep Remission at One Year Does Not Prevent Crohn's Disease Progression: Long-Term Data From the TAILORIX Trial
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Laharie, David, D’Haens, Geert, Nachury, Maria, Lambrecht, Guy, Bossuyt, Peter, Bouhnik, Yoram, Louis, Edouard, Janneke van der Woude, Christien, Buisson, Anthony, Van Hootegem, Philippe, Allez, Matthieu, Filippi, Jérôme, Brixi, Hedia, Gilletta, Cyrielle, Picon, Laurence, Baert, Filip, Vermeire, Séverine, Duveau, Nicolas, and Peyrin-Biroulet, Laurent
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- 2022
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21. Treat to target versus standard of care for patients with Crohn's disease treated with ustekinumab (STARDUST): an open-label, multicentre, randomised phase 3b trial
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Rocca, Rodolfo, Lopes, Susana, Caprioli, Flavio, Ardizzone, Sandro, Echarri Piudo, Ana, Gionchetti, Paolo, Roblin, Xavier, Seidler, Ursula, Andersson, David, Patel, Kamal, Desreumaux, Pierre, Saibeni, Simone, From, Gustav, Fedurco, Miroslav, Gregus, Milos, Bouhnik, Yoram, Luegering, Andreas, Cosintino, Rocco, Bunganic, Ivan, Ramos, Jaime, Aguas Peris, Mariam, Dewit, Olivier, Principi, Mariabeatrice, Wesley, Emma, Lago, Paula, Nancey, Stephane, Martín Arranz, María Dolores, Hindryckx, Pieter, Orlando, Ambrogio, Geccherle, Andrea, Annunziata, Maria Laura, Hayee, Bu'hussain, Balaz, Jozef, Portela, Francisco, Gilletta, Cyrielle, Kucharzik, Torsten, Mínguez, Miguel, Gisbert, Javier Pérez, Casbas, Ana Gutiérrez, Louis, Edouard, Marino, Marco, Parkes, Gareth, Cummings, Fraser, Jharap, Bindia, Kjeldsen, Jens, Correia, Luís, Ministro, Paula, Ebert, Matthias, Hertervig, Erik, Staessen, Dirk, Dutré, Joris, Colard, Arnaud, Morrison, Graham, Glerup, Henning, Dahlerup, Jens Frederik, Wolfhagen, Frank, Batovsky, Marian, Molnar, Martin, Kadleckova, Barbora, Caldeira, Paulo, Laharie, David, Hebuterne, Xavier, Bonaz, Bruno, Allez, Matthieu, Fischer, Andreas, Hinojosa Del Val, Joaquín Ernesto, Ciria, Miriam Mañosa, Herrera Justiniano, Jose Manuel, Soderman, Charlotte, Chandy, Rajiv, Mowat, Craig, Irving, Peter, Fallingborg, Jan, Matous, Jan, Douda, Tomas, Altwegg, Romain, Benitez, Jose Manuel, Arroyo Villarino, María Teresa, Capón, Jordi Guardiola, Vicenc, Daniel Ginard, Dewint, Pieter, Almer, Sven, Kindt, Sebastien, Danese, Silvio, Vermeire, Severine, D'Haens, Geert, Panés, Julian, Dignass, Axel, Magro, Fernando, Nazar, Maciej, Le Bars, Manuela, Lahaye, Marjolein, Ni, Lioudmila, Bravata, Ivana, Lavie, Frederic, Daperno, Marco, Lukáš, Milan, Armuzzi, Alessandro, Löwenberg, Mark, Gaya, Daniel R, and Peyrin-Biroulet, Laurent
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- 2022
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22. Impact of HIV Infection on the Course of Inflammatory Bowel Disease and Drug Safety Profile: A Multicenter GETAID Study
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Guillo, Lucas, Uzzan, Mathieu, Beaugerie, Laurent, Gornet, Jean-Marc, Amiot, Aurélien, Pelletier, Anne-Laure, Altwegg, Romain, Laharie, David, Abitbol, Vered, Filippi, Jérôme, Goutorbe, Felix, Nachury, Maria, Nancey, Stéphane, Viennot, Stéphanie, Reenaers, Catherine, Amil, Morgane, Caillo, Ludovic, Buisson, Anthony, Collins, Michael, Picon, Laurence, Vidon, Mathias, Benezech, Alban, Rabaud, Christian, Baumann, Cédric, Rousseau, Hélène, Dubourg, Grégory, Serrero, Mélanie, and Peyrin-Biroulet, Laurent
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- 2022
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23. Long‐term safety and efficacy of filgotinib for the treatment of moderately to severely active ulcerative colitis: Interim analysis from up to 4 years of follow‐up in the SELECTION open‐label long‐term extension study.
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Feagan, Brian G., Matsuoka, Katsuyoshi, Rogler, Gerhard, Laharie, David, Vermeire, Séverine, Danese, Silvio, Loftus, Edward V., Beales, Ian, Schreiber, Stefan, Kim, Hyo Jong, Faes, Margaux, de Haas, Angela, Masior, Tomasz, Rudolph, Christine, and Peyrin‐Biroulet, Laurent
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ULCERATIVE colitis ,QUALITY of life ,PREVENTIVE medicine ,BIOMARKERS ,SUCCESSFUL people - Abstract
Summary: Background: Filgotinib, an oral, once‐daily, Janus kinase 1 preferential inhibitor, is an approved treatment for moderately to severely active ulcerative colitis. Aims: The aim of this study is to assess the safety and efficacy of continued filgotinib therapy over ~4 years in the long‐term extension of the phase 2b/3 SELECTION trial (SELECTIONLTE; NCT02914535). Methods: In this interim analysis of SELECTIONLTE, SELECTION completers (week 10 responders to filgotinib who completed the maintenance study) continued their assigned treatment (double‐blind filgotinib 200 mg [FIL200] or filgotinib 100 mg) and SELECTION week 10 non‐responders received open‐label FIL200. We assessed safety by adverse events (AEs), and efficacy by partial Mayo Clinic Score (pMCS), inflammatory biomarkers and health‐related quality of life (HRQoL). We compared safety and efficacy between achievers and non‐achievers of a multi‐component endpoint, comprehensive disease control (CDC), comprising symptomatic, endoscopic, inflammatory biomarker and HRQoL improvements. Results: Data for completers (n = 250) and non‐responders (n = 372) were reported for ≤202 weeks. AE occurrences were low and consistent with previous analyses. The as‐observed proportion of FIL200‐treated patients in pMCS, biomarker and HRQoL remission during SELECTIONLTE remained high among completers (week 144: 80.0%, 86.4% and 86.0%, respectively) and increased among non‐responders (week 192: 62.1%, 76.7% and 59.3%, respectively). Significantly higher proportions of CDC achievers at SELECTION week 58 achieved pMCS, IBDQ and corticosteroid‐free pMCS remission than non‐achievers, up to LTE week 96. Conclusions: Filgotinib induced and maintained symptomatic remission and improved HRQoL over 4 years. Safety results showed a proven long‐term benefit–risk profile. FIL200‐treated CDC achievers had better long‐term outcomes than non‐achievers. [ABSTRACT FROM AUTHOR]
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- 2024
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24. Etrolizumab as induction and maintenance therapy for ulcerative colitis in patients previously treated with tumour necrosis factor inhibitors (HICKORY): a phase 3, randomised, controlled trial
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Aguilar, Humberto, Ahmad, Tariq, Akriviadis, Evangelos, Aldeguer Mante, Xavier, Allez, Matthieu, Altorjay, Istvan, Ananthakrishnan, Ashwin, Andersen, Vibeke, Andreu Garcia, Montserrat, Armuzzi, Alessandro, Aumais, Guy, Avni-Biron, Irit, Axler, Jeffrey, Ayub, Kamran, Jr., Baert, Filip, Bafutto, Mauro, Bamias, George, Bassan, Isaac, Baum, Curtis, Beaugerie, Laurent, Behm, Brian, Bekal, Pradeep, Bennett, Michael, Bermejo San Jose, Fernando, Bernstein, Charles, Bettenworth, Dominik, Bhaskar, Sudhir, Biancone, Livia, Bilir, Bahri, Blaeker, Michael, Bloom, Stuart, Bohman, Verle, Jr., Bosques Padilla, Francisco Javier, Bossuyt, Peter, Bouhnik, Yoram, Bouma, Gerd, Bourdages, Raymond, Brand, Stephan, Bressler, Brian, Brückner, Markus, Buening, Carsten, Carbonnel, Franck, Caves, Thomas, Chapman, Jonathon, Cheon, Jae Hee, Chiba, Naoki, Chioncel, Camelia, Christodoulou, Dimitrios, Clodi, Martin, Cohen, Albert, Corazza, Gino Roberto, Corlin, Richard, Cosintino, Rocco, Cummings, Fraser, Dalal, Robin, Danese, Silvio, De Maeyer, Marc, De Magalhães Francesconi, Carlos Fernando, De Silva, Aminda, Debinski, Henry, Desreumaux, Pierre, Dewit, Olivier, D'Haens, Geert, Di Felice Boratto, Sandra, Ding, John Nik, Dixon, Tyler, Dryden, Gerald, Jr., Du Vall, George Aaron, Ebert, Matthias, Echarri Piudo, Ana, Ehehalt, Robert, Elkhashab, Magdy, Ennis, Craig, Etzel, Jason, Fallingborg, Jan, Feagan, Brian, Fejes, Roland, Ferraz de Campos Mazo, Daniel, Ferreira de Almeida Borges, Valéria, Fischer, Andreas, Fixelle, Alan, Fleisher, Mark, Fowler, Sharyle, Freilich, Bradley, Friedenberg, Keith, Fries, Walter, Fulop, Csaba, Fumery, Mathurin, Fuster, Sergio, G Kiss, Gyula, Garcia Lopez, Santiago, Gassner, Sonja, Gill, Kanwar, Gilletta de Saint Joseph, Cyrielle, Ginsburg, Philip, Gionchetti, Paolo, Goldin, Eran, Goldis, Adrian-Eugen, Gomez Jaramillo, Hector Alejandro, Gonciarz, Maciej, Gordon, Glenn, Green, Daniel, Grimaud, Jean-Charles, Guajardo Rodriguez, Rogelio, Gurzo, Zoltan, Gutierrez, Alexandra, Gyökeres, Tibor, Hahm, Ki Baik, Hanauer, Stephen, Hanson, John, Harlan III, William, Hasselblatt, Peter, Hayee, Buhussain, Hebuterne, Xavier, Hendy, Peter, Heyman, Melvin, Higgins, Peter, Hilal, Raouf, Hindryckx, Pieter, Hoentjen, Frank, Hoffmann, Peter, Holtkamp-Endemann, Frank, Holtmann, Gerald, Horvat, Gyula, Howaldt, Stefanie, Huber, Samuel, Ibegbu, Ikechukwu, Iborra Colomino, Maria Isabel, Irving, Peter, Isaacs, Kim, Jagarlamudi, Kiran, Jain, Rajesh, Jankiel Miszputen, Sender, Jansen, Jeroen, Jones, Jennifer, Juillerat, Pascal, Karagiannis, John, Karyotakis, Nicholas, Kaser, Arthur, Katz, Lior, Katz, Seymour, Katz, Leo, Kaur, Nirmal, Kazenaite, Edita, Khanna, Reena, Khurana, Sunil, Kim, Joo Sung, Kim, Young-Ho, Kim, Sung Kook, Kim, Dongwoo, Klaus, Jochen, Kleczkowski, Dariusz, Kohout, Pavel, Korczowski, Bartosz, Kouklakis, Georgios, Koutroubakis, Ioannis, Krause, Richard, Kristof, Tunde, Kronborg, Ian, Krummenerl, Annette, Kupcinskas, Limas, Laborda Molteni, Jorge, Laharie, David, Lahat-zok, Adi, Lee, Jonghun, Lee, Kang-Moon, Leong, Rupert, Levine, Henry, Limdi, Jimmy, Lindsay, James, Lodhia, Nilesh, Loftus, Edward, Longman, Randy, Lopez Serrano, Pilar, Louis, Edouard, Louzada Pereira, Maria Helena, Lowe, John, Lueth, Stefan, Lukas, Milan, Maconi, Giovanni, Macrae, Finlay, Madi-Szabo, Laszlo, Mahadevan-Velayos, Uma, Malluta, Everson Fernando, Mana, Fazia, Mannon, Peter, Mantzaris, Gerasimos, Marin Jimenez, Ignacio, Martin Arranz, Maria Dolores, Mateescu, Radu-Bogdan, Mazzoleni, Felipe, Meder, Agnieszka, Melzer, Ehud, Mertens, Jessica, Mimidis, Konstantinos, Mitchell, Brent, Molnar, Tamas, Moore, Gregory, Morales Garza, Luis Alonso, Mountifield, Reme, Muls, Vinciane, Murray, Charles, Nagy, Bela, Neurath, Markus, Nguyen, Augustin, Panaccione, Remo, Pandak, William, Panes Diaz, Julian, Park, Jihye, Pastorelli, Luca, Patel, Bhaktasharan, Peck-Radosavljevic, Markus, Pecsi, Gyula, Peerani, Farhad, Perez Gisbert, Javier, Pesta, Martin, Petryka, Robert, Peyrin-Biroulet, Laurent, Phillips, Raymond, Pierik, Marieke, Pratha, Vijayalakshmi, Prochazka, Vlastimil, Racz, Istvan, Radford-Smith, Graham, Ramos Castañeda, Daniel, Ramos Júnior, Odery, Regula, Jaroslaw, Reimund, Jean-Marie, Robbins, Bryan, Roblin, Xavier, Rogai, Francesca, Rogler, Gerhard, Rozciecha, Jerzy, Rubin, David, Ruiz Flores, Azalia Yuriria, Rupinski, Maciej, Rydzewska, Grazyna, Saha, Sumona, Saibeni, Simone, Salamon, Agnes, Sallo, Zoltan, Salzberg, Bruce, Samuel, Douglas, Samuel, Sunil, Sandborn, William, Savarino, Edoardo Vincenzo, Schirbel, Anja, Schnabel, Robert, Schreiber, Stefan, Scott, John, Sedghi, Shahriar, Seibold, Frank, Seidelin, Jakob, Seidler, Ursula, Shaban, Ahmad, Shafran, Ira, Sheikh, Aasim, Sherman, Alex, Shirin, Haim, Smolinski, Patryk, Song, Geun Am, Soufleris, Konstantinos, Speight, Alexander, Staessen, Dirk, Stallmach, Andreas, Staun, Michael, Stein, Daniel, Steinhart, Hillary, Stifft, Jonathas, Stokesberry, David, Sturm, Andreas, Sultan, Keith, Szekely, Gyorgy, Tagore, Kuldeep, Tanno, Hugo, Thin, Lena, Thiwan, Syed, Thomas, Carlton, Tichy, Michal, Toth, Gabor Tamas, Tulassay, Zsolt, Ulbrych, Jan, Valentine, John, Varga, Marta, Vasconcellos, Eduardo, Vaughn, Byron, Velasco, Brenda, Velazquez, Francisco, Vermeire, Severine, Villa, Erica, Vincze, Aron, Vogelsang, Harald, Volfova, Miroslava, Vuitton, Lucine, Vyhnalek, Petr, Wahab, Peter, Walldorf, Jens, Waterman, Mattitiahu, Weber, John, Weiss, L. Michael, Wiechowska-Kozlowska, Anna, Wiesner, Elise, Witthoeft, Thomas, Wohlman, Robert, Wozniak-Stolarska, Barbara, Yacyshyn, Bruce, Ye, Byong-Duk, Younes, Ziad, Yukie Sassaki, Lígia, Zaltman, Cyrla, Zeuzem, Stefan, Hart, Ailsa, Long, Millie, Loftus, Edward V, Jr, Ostad-Saffari, Elham, Scalori, Astrid, Oh, Young S, Tole, Swati, Chai, Akiko, Pulley, Jennifer, Lacey, Stuart, and Sandborn, William J
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- 2022
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25. Etrolizumab versus infliximab for the treatment of moderately to severely active ulcerative colitis (GARDENIA): a randomised, double-blind, double-dummy, phase 3 study
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Aboo, Nazimuddin, Ahmad, Tariq, Aldeguer Mante, Xavier, Allez, Matthieu, Almer, Sven, Altwegg, Romain, Andreu Garcia, Montserrat, Arasaradnam, Ramesh, Ardizzone, Sandro, Armuzzi, Alessandro, Arnott, Ian, Aumais, Guy, Avni-Biron, Irit, Barrow, Peter, Beales, Ian, Bermejo San Jose, Fernando, Bezuidenhout, Abraham, Biancone, Livia, Blaeker, Michael, Bloom, Stuart, Bokemeyer, Bernd, Bossa, Fabrizio, Bossuyt, Peter, Bouguen, Guillaume, Bouhnik, Yoram, Bouma, Gerd, Bourdages, Raymond, Bourreille, Arnaud, Boustiere, Christian, Brabec, Tomas, Brand, Stephan, Buening, Carsten, Buisson, Anthony, Cadiot, Guillaume, Calvet Calvo, Xavier, Carbonnel, Franck, Carpio, Daniel, Cheon, Jae Hee, Chiba, Naoki, Chioncel, Camelia, Cimpoeru, Nicoleta-Claudia, Clodi, Martin, Corazza, Gino Roberto, Cosintino, Rocco, Cotter, Jose, Creed, Thomas, Cummings, Fraser, Danese, Silvio, de' Angelis, Gian Luigi, De Maeyer, Marc, Desai, Milind, Desilets, Etienne, Desreumaux, Pierre, Dewit, Olivier, D'Haens, Geert, Dinter, Johanna, Dobru, Ecaterina Daniela, Douda, Tomas, Dumitrascu, Dan Lucian, Ebert, Matthias, Echarri Piudo, Ana, Elkhashab, Magdy, Eun, Chang Soo, Feagan, Brian, Fejes, Roland, Fidalgo, Catarina, Fishman, Sigal, Flourié, Bernard, Fowler, Sharyle, Fries, Walter, Fulop, Csaba, Fumery, Mathurin, G Kiss, Gyula, Gassner, Sonja, Gaya, Daniel, Germanà, Bastianello, Gheorghe, Liliana Simona, Gilletta de Saint Joseph, Cyrielle, Gionchetti, Paolo, Goldis, Adrian-Eugen, Gonçalves, Raquel, Grimaud, Jean-Charles, Gyökeres, Tibor, Hagege, Herve, Haidar, Andrei, Hartmann, Heinz, Hasselblatt, Peter, Hayee, Buhussain, Hebuterne, Xavier, Hellström, Per, Hindryckx, Pieter, Hlavova, Helena, Hoentjen, Frank, Howaldt, Stefanie, Hrdlicka, Ludek, Huh, Kyu Chan, Iborra Colomino, Maria Isabel, Ionita-Radu, Florentina, Irving, Peter, Jahnsen, Jørgen, Jang, ByungIk, Jansen, Jeroen, Jeon, Seong Woo, Jover Martinez, Rodrigo, Juillerat, Pascal, Karlén, Per, Kaser, Arthur, Keil, Radan, Kejariwal, Deepak, Keret, Dan, Khanna, Reena, Kim, Dongwoo, Kim, Duk Hwan, Kim, Hyo-Jong, Kim, Hyun-Soo, Kim, Joo Sung, Kim, Kueongok, Kim, Kyung-Jo, Kim, Sung Kook, Kim, Young-Ho, Klaus, Jochen, Kohn, Anna, Kojecky, Vladimir, Koo, Ja Seol, Kozak, Robert, Kremer, Milan, Kristof, Tunde, Kruger, Frederik, Laharie, David, Lahat-zok, Adi, Landa, Evgeny, Lee, Jonghun, Lee, Kang-Moon, Lee, Kook Lae, Lee, YooJin, Lenze, Frank, Lim, Wee Chian, Limdi, Jimmy, Lindsay, James, Lopez Serrano, Pilar, Louis, Edouard, Lueth, Stefan, Lukas, Milan, Maconi, Giovanni, Mana, Fazia, Mann, Steven, Mansfield, John, Marchi, Santino, Marino, Marco, Marshall, John, Martin Arranz, Maria Dolores, Mateescu, Radu-Bogdan, McLaughlin, John, McLaughlin, Simon, Melzer, Ehud, Mertens, Jessica, Mitrut, Paul, Molnar, Tamas, Muls, Vinciane, Munuswamy, Pushpakaran, Murray, Charles, Naftali, Timna, Naidoo, Visvakuren, Nanabhay, Yusuf, Negreanu, Lucian, Nguyen, Augustin, Ochsenkuehn, Thomas, Orlando, Ambrogio, Panaccione, Remo, Panes Diaz, Julian, Paritsky, Maya, Park, Dong Il, Park, Jihye, Pastorelli, Luca, Peck-Radosavljevic, Markus, Peerani, Farhad, Perez Gisbert, Javier, Peyrin-Biroulet, Laurent, Picon, Laurence, Pierik, Marieke, Ponich, Terry, Portela, Francisco, Prins, Maartens Jeroen, Racz, Istvan, Rahman, Khan Fareed, Reimund, Jean-Marie, Reinshagen, Max, Roblin, Xavier, Rocca, Rodolfo, Rogai, Francesca, Rogler, Gerhard, Salamon, Agnes, Salazar, Ennaliza, Sallo, Zoltan, Samuel, Sunil, Sans Cuffi, Miquel de los Santos, Savarino, Edoardo Vincenzo, Savarino, Vincenzo, Savoye, Guillaume, Schreiber, Stefan, Seicean, Andrada, Selinger, Christian, Serra, David Martins, Shim, Hang Hock, Shin, SungJae, Siegmund, Britta, Siffledeen, Jesse, Simmonds, Wayne, Smid, Jan, Sollano, Jose, Song, Geun Am, Speight, Alexander, Sporea, Ioan, Staessen, Dirk, Stancu, George, Steel, Alan, Stepek, David, Stoica, Victor, Sturm, Andreas, Szekely, Gyorgy, Tan, Teck Kiang, Taxonera Samso, Carlos, Thomson, John, Tichy, Michal, Toth, Gabor Tamas, Tulassay, Zsolt, Vangeli, Marcello, Varga, Marta, Vieira, Ana, Viennot, Stephanie, Villa, Erica, Vitek, Petr, Vogelsang, Harald, Vyhnalek, Petr, Wahab, Peter, Walldorf, Jens, Ye, Byong Duk, Ziady, Christopher, Colombel, Jean-Frederic, Gisbert, Javier P, Hayee, Bu'hussain, Reinisch, Walter, Tyrrell, Helen, Oh, Young S, Tole, Swati, Chai, Akiko, Chamberlain-James, Kirsten, and Tang, Meina Tao
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- 2022
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26. Controversies in medical vs surgical management of ileocecal crohn's disease
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Maggiori, Léon, primary and Laharie, David, additional
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- 2024
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27. Methotrexate and IBD: mechanisms of action, indications/use
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Nancey, Stéphane, additional and Laharie, David, additional
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- 2024
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28. Novel medical strategies in acute severe ulcerative colitis
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Calméjane, Louis, additional, Laharie, David, additional, Kirchgesner, Julien, additional, and Uzzan, Mathieu, additional
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- 2024
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29. Evolution of Endoscopic Lesions in Steroid-Refractory Acute Severe Ulcerative Colitis Responding to Infliximab or Cyclosporine
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Laharie, David, Bourreille, Arnaud, Branche, Julien, Allez, Matthieu, Bouhnik, Yoram, Filippi, Jerome, Zerbib, Frank, Savoye, Guillaume, Vuitton, Lucine, Moreau, Jacques, Amiot, Aurelien, Beaugerie, Laurent, Ricart, Elena, Dewit, Olivier, Lopez-Sanroman, Antonio, Fumery, Mathurin, Carbonnel, Franck, Buisson, Anthony, Coffin, Benoit, Roblin, Xavier, van Assche, Gert, Esteve, Maria, Farkkila, Martti, Gisbert, Javier P., Marteau, Philippe, Nahon, Stephane, de Vos, Martine, Peyrin-Biroulet, Laurent, and Mary, Jean-Yves
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- 2021
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30. Infliximab Exposure Associates With Radiologic Evidence of Healing in Patients With Crohn’s Disease
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Lambrecht, Guy, Buisson, Anthony, Bouhnik, Yoram, Woude, Janneke Vander, Van Hootegem, Philippe, Moreau, Jacques, Louis, Edouard, Franchimont, Denis, De Vos, Martine, Mana, Fazia, Brixi, Hedia, Allez, Matthieu, Caenepeel, Philip, Aubourg, Alexandre, Oldenburg, Bas, Pierik, Marieke, Chevret, Sylvie, Bossuyt, Peter, Dreesen, Erwin, Rimola, Jordi, Devuysere, Sofie, De Bruecker, Yves, Vanslembrouck, Ragna, Laurent, Valérie, Zappa, Magaly, Savoye-Collet, Céline, Pariente, Benjamin, Filippi, Jérôme, Baert, Filip, D’Haens, Geert, Laharie, David, Peyrin-Biroulet, Laurent, and Vermeire, Séverine
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- 2021
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31. Patients’ real-world experience with inflammatory bowel disease: A cross-sectional survey in tertiary care centres from the GETAID group
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Amiot, Aurelien, Tadbiri, Sara, Gagniere, Charlotte, Tannoury, Jenny, Nachury, Maria, Pariente, Benjamin, Wils, Pauline, Bouhnik, Yoram, Stefanescu, Carmen, Treton, Xavier, Serrero, Melanie, Filippi, Jerome, Hébuterne, Xavier, Arab, Nadia, Cluzeau, Virginie, Roblin, Xavier, Tedesco, Emilie Del, Beaugerie, Laurent, Seksik, Philippe, Bourrier, Anne, Landmann, Cecilia, Kirchgesner, Julien, Sokol, Harry, Bouguen, Guillaume, Siproudhis, Laurent, DeWitte, Marie, Franchimont, Denis, Savoye, Guillaume, Buisson, Anthony, Louis, Edouard, Reenaers, Catherine, Nancey, Stephane, Boschetti, Gilles, Gay, Claire, Danion, Pauline, Flourié, Bernard, Abitbol, Vered, Malamut, Georgia, Reimund, Jean-Marie, Caron, Benedicte, DeWitt, Olivier, Vuitton, Lucine, Mathieu, Nicolas, Pestour, Sandie, Peyrin-Biroulet, Laurent, Zallot, Camille, Gilletta, Cyrielle, Allez, Matthieu, Gornet, Jean-Marc, Baudry, Clotilde, Viennot, Stephanie, Bourreille, Arnaud, Trang-Poisson, Caroline, Dib, Nina, Brixi, Hedi, Cadiot, Guillaume, Boualit, Medina, Painchart, Claire, Plastaras, Laurianne, Altwegg, Romain, Boivineau, Lucile, Fumery, Mathurin, Caillo, Ludovic, Laharie, David, Riviere, Pauline, Poullenot, Florian, Coffin, Benoit, Duboc, Henri, Nahon, Stephane, Tavernier, Noemie, Simon, Marion, Coulibaly, Baya, Amil, Morgane, Nicolas, Duveau, Khater, Sherine, Kaassis, Mehdi, Goutorbe, Felix, Moussata, Driffa, Picon, Laurence, DeWit, Olivier, and Matthieu, Nicolas
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- 2021
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32. Rates of Postoperative Recurrence of Crohn’s Disease and Effects of Immunosuppressive and Biologic Therapies
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Rivière, Pauline, Vermeire, Séverine, Irles-Depe, Marie, Van Assche, Gert, Rutgeerts, Paul, Denost, Quentin, Wolthuis, Albert, D’Hoore, Andre, Laharie, David, and Ferrante, Marc
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- 2021
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33. Lymphoma in Patients with Inflammatory Bowel Disease: A Multicentre Collaborative Study Between GETAID and LYSA
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Muller, Marie, Broséus, Julien, Guilloteau, Adrien, Wasse, Stéphane, Thiéblemont, Catherine, Nancey, Stéphane, Cadiot, Guillaume, Amiot, Aurelien, Laharie, David, Vieujean, Sophie, Bouhnik, Yoram, Martineau, Chloé, Michiels, Christophe, Hébuterne, Xavier, Savoye, Guillaume, Franchimont, Denis, Seksik, Philippe, Beaugerie, Laurent, Maynadié, Marc, Feugier, Pierre, Peyrin-Biroulet, Laurent, Muller, Marie, Broséus, Julien, Guilloteau, Adrien, Wasse, Stéphane, Thiéblemont, Catherine, Nancey, Stéphane, Cadiot, Guillaume, Amiot, Aurelien, Laharie, David, Vieujean, Sophie, Bouhnik, Yoram, Martineau, Chloé, Michiels, Christophe, Hébuterne, Xavier, Savoye, Guillaume, Franchimont, Denis, Seksik, Philippe, Beaugerie, Laurent, Maynadié, Marc, Feugier, Pierre, and Peyrin-Biroulet, Laurent
- Abstract
Background: Inflammatory bowel disease [IBD] is associated with an increased risk of developing lymphoma. Although recent data have clarified the epidemiology of lymphoma in IBD patients, the clinical and pathological characteristics of lymphoma in IBD remain poorly known. Methods: Patients with IBD and lymphoma were retrospectively identified in the framework of a national collaborative study including the Groupe d’Étude Thérapeutique des Affections Inflammatoires du Tube Digestif [GETAID] and the Lymphoma Study Association [LYSA]. We characterized clinical and prognostic features for the three most frequent lymphoma subtypes occurring in IBD. We performed a multicentre case-control study. Controls [lymphoma de novo] were matched [5:1] to cases on gender, age at diagnosis, lymphoma subtype, year of diagnosis, and IPI/FLIPI indexes. Overall survival and progression-free survival were compared between cases and controls. Results: In total, 133 IBD patients with lymphoma were included [males = 62.4%, median age at lymphoma diagnosis = 49 years in males; 42 years in females]. Most had Crohn’s disease [73.7%] and were exposed to thiopurines [59.4%]. The most frequent lymphoma subtypes were diffuse large B cell lymphoma [DLBCL, 45.1%], Hodgkin lymphoma [HL, 18.8%], and follicular lymphoma [FL, 10.5%]. When matched with 365 controls, prognosis was improved in IBD patients with DLBCL compared to controls [p = 0.0064, hazard ratio = 0.36] or similar [HL and FL]. Conclusions: Lymphomas occurring in IBD patients do not seem to have a worse outcome than in patients without IBD. Due to the rarity of this situation, such patients should be managed in expert centres., SCOPUS: ar.j, info:eu-repo/semantics/published
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- 2024
34. Indications de l’autogreffe de cellules hématopoïétiques dans la Maladie de Crohn : recommandations de la Société francophone de greffe de moelle et de thérapie cellulaire
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Puyade, Mathieu, Treton, Xavier, Alric, Laurent, Badoglio, Manuela, Castilla Llorente, Cristina, Fotsing, Ginette, Marjanovic, Zora, Rovira, Montserrat, Terriou, Louis, Torregrosa Díaz Jose, Miguel, Tran-Minh, My-Linh, Allez, Matthieu, Pugnet, Grégory, Laharie, David, Yakoub-Agha, Ibrahim, and Farge, Dominique
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- 2020
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35. Patient preferences for adalimumab in inflammatory bowel disease: a nationwide study from the GETAID.
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Caron, Bénédicte, Seksik, Philippe, Buisson, Anthony, Wils, Pauline, Savoye, Guillaume, Stefanescu, Carmen, Laharie, David, Guillo, Lucas, Abitbol, Vered, Bonnet, Joelle, Altwegg, Romain, Vuitton, Lucine, Moussata, Driffa, Bourreille, Arnaud, Biron, Amélie, Gilletta, Cyrielle, Fumery, Mathurin, Nahon, Stephane, Nancey, Stephane, and Camara, Houda
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PATIENT satisfaction ,INFLAMMATORY bowel diseases ,SUBCUTANEOUS injections ,SATISFACTION ,ONE-way analysis of variance - Abstract
Background: Several adalimumab preparations are now available for patients with inflammatory bowel disease (IBD). Comparative satisfaction and tolerability are unknown. Objectives: This study investigated IBD patient satisfaction with approved adalimumab biosimilars and their originator. Design: In this cross-sectional study, we included 941 consecutive adalimumab-treated patients with IBD across 45 centres affiliated with the Groupe d'Etude Therapeutique des Affections Inflammatoires du tube Digestif who completed a satisfaction questionnaire comprising four items each rated by a 10-point scale. Methods: The differences in responses were performed using a one-way analysis of variance followed by Tukey's honest significant difference test. Results: The most commonly used drugs at inclusion were Humira
® (436/941, 46.3%), Amgevita® (177/941, 18.8%) and Hulio® (105/941, 11.2%). The mean overall satisfaction rate with adalimumab was 8.5 (standard deviation 1.8). Overall satisfaction was significantly higher in patients treated with Humira (8.6 (1.5)), Hulio (8.6 (1.8)) or Amgevita (8.5 (1.4)) (p < 0.05). Satisfaction with the subcutaneous injection form was higher for patients treated with Yuflyma® (9.0 (1.4)), Humira (8.9 (1.3)) and Hulio (8.9 (1.7)) (p < 0.05). A total of 299 patients (31.8%) described injection site reactions. In all, 223 patients (23.7%) reported being previously treated with another adalimumab of which (32/223, 14.3%) discontinued treatment due to side effects. Conclusion: In this real-world setting, patients with IBD had a high level of satisfaction with adalimumab treatment, with some differences in terms of overall satisfaction and satisfaction with the injection device. [ABSTRACT FROM AUTHOR]- Published
- 2024
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36. Pragmatic Trial Design to Compare Real-world Effectiveness of Different Treatments for Inflammatory Bowel Diseases: The PRACTICE-IBD European Consensus.
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Fantini, Massimo Claudio, Fiorino, Gionata, Colli, Agostino, Laharie, David, Armuzzi, Alessandro, Caprioli, Flavio Andrea, Gisbert, Javier P, Kirchgesner, Julien, Macaluso, Fabio Salvatore, Magro, Fernando, Ghosh, Subrata, and group, PRACTICE-IBD study
- Abstract
Background and Aims Pragmatic studies designed to test interventions in everyday clinical settings can successfully complement the evidence from registration and explanatory clinical trials. The European consensus project PRACTICE-IBD was developed to identify essential criteria and address key methodological issues needed to design valid, comparative, pragmatic studies in inflammatory bowel diseases [BDs]. Methods Statements were issued by a panel of 11 European experts in IBD management and trial methodology, on four main topics: [I] study design; [II] eligibility, recruitment and organisation, flexibility; [III] outcomes; [IV] analysis. The consensus process followed a modified Delphi approach, involving two rounds of assessment and rating of the level of agreement [1 to 9; cut-off ≥7 for approval] with the statements by 18 additional European experts in IBD. Results At the first voting round, 25 out of the 26 statements reached a mean score ≥7. Following the discussion that preceded the second round of voting, it was decided to eliminate two statements and to split one into two. At the second voting round, 25 final statements were approved: seven for study design; six for eligibility, recruitment and organisation, flexibility; eight for outcomes; and four for analysis. Conclusions Pragmatic, randomised, clinical trials can address important questions in IBD clinical practice, and may provide complementary, high-level evidence, as long as they follow a methodologically rigorous approach. These 25 statements intend to offer practical guidance in the design of high-quality, pragmatic, clinical trials that can aid decision making in choosing a management strategy for IBDs. [ABSTRACT FROM AUTHOR]
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- 2024
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37. Long‐term risk of delayed postoperative Crohn's disease recurrence in patients with no or mild endoscopic recurrence at first assessment.
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Mañosa, Míriam, Rivière, Pauline, de Greef, Ine, Oller, Blanca, Roig, Cristina, Calafat, Margalida, Garcia‐Planella, Esther, Laharie, David, Ferrante, Marc, and Domènech, Eugeni
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CROHN'S disease ,DISEASE relapse - Abstract
Background: Early endoscopic evaluation is recommended for assessment of postoperative recurrence (POR) of Crohn's disease (CD) but no further monitoring recommendations are available. Aim: To evaluate the long‐term outcome of patients without endoscopic POR at first endoscopic assessment. Methods: Retrospective four‐centre study including consecutive CD patients with ileocolonic resection (ICR) without endoscopic POR (Rutgeerts score i0‐i1) at first endoscopic assessment performed within 18 months from ICR. All patients had a clinical follow‐up ≥24 months and at least one further endoscopic assessment. Main outcomes were endoscopic, clinical and surgical POR, need for rescue therapy and "delayed POR" (any need for rescue therapy or clinical or surgical POR) during follow‐up. Results: Overall, 183 patients were included (79% with risk factors for POR, 44% without postoperative prophylaxis). Endoscopic POR was observed in 42% of patients. Clinical POR‐free survival was 89.4% and 81.5% at 3 and 5 years, and delayed POR‐free survival was 76.9% and 63.4% at 5 and 10 years, respectively. In multivariate analysis, postoperative prophylaxis (HR.55; 95% CI.325–.942) and active smoking (HR 1.72; 95%CI 1.003–2.962) were independent risk factors for clinical POR, whereas presence of mild endoscopic lesions at index ileocolonoscopy (i1) was the only risk factor for delayed POR (HR 1.824; 95% CI 1.108–3.002). Conclusions: Long‐term risk of POR among patients with no or mild endoscopic lesions at first ileocolonoscopy after surgery is steadily low, being higher among smokers, in the absence of postoperative prophylaxis and when mild endoscopic lesions are observed in the first endoscopic assessment. [ABSTRACT FROM AUTHOR]
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- 2024
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38. Long-term outcome of Crohn's disease patients with upper gastrointestinal stricture: A GETAID study
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Lambin, Thomas, Amiot, Aurélien, Stefanescu, Carmen, Gornet, Jean-Marc, Seksik, Philippe, Laharie, David, Reenaers, Catherine, Bourreille, Arnaud, Cadiot, Guillaume, Carbonnel, Franck, Dib, Nina, Fumery, Mathurin, Gilletta de St Joseph, Cyrielle, Filippi, Jérôme, Viennot, Stéphanie, Plastaras, Laurianne, Coffin, Benoit, Serrero, Mélanie, Nahon, Stéphane, Pineton de Chambrun, Guillaume, Rahier, Jean-François, Roblin, Xavier, Boualit, Médina, Bouguen, Guillaume, Peyrin-Biroulet, Laurent, and Pariente, Benjamin
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- 2020
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39. Variation of faecal calprotectin level within the first three months after bowel resection is predictive of endoscopic postoperative recurrence in Crohn's disease
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Boube, Mathilde, Laharie, David, Nancey, Stéphane, Hebuterne, Xavier, Fumery, Mathurin, Pariente, Benjamin, Roblin, Xavier, Peyrin-biroulet, Laurent, Minet-quinard, Régine, Pereira, Bruno, Bommelaer, Gilles, and Buisson, Anthony
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- 2020
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40. Systematic Review and External Validation of Prediction Models Based on Symptoms and Biomarkers for Identifying Endoscopic Activity in Crohn's Disease
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Brand, Eelco C., Elias, Sjoerd G., Minderhoud, Itta M., van der Veen, Julius J., Baert, Filip J., Laharie, David, Bossuyt, Peter, Bouhnik, Yoram, Buisson, Anthony, Lambrecht, Guy, Louis, Edouard, Pariente, Benjamin, Pierik, Marieke J., van der Woude, C. Janneke, D’Haens, Geert R.A. M., Vermeire, Séverine, and Oldenburg, Bas
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- 2020
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41. Oral Curcumin No More Effective Than Placebo in Preventing Recurrence of Crohn's Disease After Surgery in a Randomized Controlled Trial
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Coban, Dilek, Dodel, Marie, Goutorbe, Félix, Allimant, Christophe, Reymond, Maud, Dapoigny, Michel, Rouquette, Olivier, Vazeille, Emilie, Poullenot, Florian, Riviere, Pauline, Boschetti, Gilles, Filippi, Jérôme, Del Tedesco, Emilie, Veyrard, Pauline, Pariente, Benjamin, Wils, Pauline, Zallot, Camille, Yzet, Clara, Brazier, Franck, Bommelaer, Gilles, Laharie, David, Nancey, Stéphane, Hebuterne, Xavier, Roblin, Xavier, Nachury, Maria, Peyrin-Biroulet, Laurent, Fumery, Mathurin, Richard, Damien, Pereira, Bruno, Goutte, Marion, and Buisson, Anthony
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- 2020
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42. Implementation of infliximab standardized doses after pharmacokinetic modelization in a cohort of patients with Crohn’s disease
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Poullenot, Florian, Ollivier, Julien, Rivière, Pauline, Sauvaget, Lucie, Berroneau, Aude, Djabarouti, Sarah, Xuereb, Fabien, Zerbib, Frank, Breilh, Dominique, and Laharie, David
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- 2020
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43. Real-world evidence of tofacitinib effectiveness and safety in patients with refractory ulcerative colitis
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Lair-Mehiri, Loriane, Stefanescu, Carmen, Vaysse, Thibaut, Laharie, David, Roblin, Xavier, Rosa, Isabelle, Treton, Xavier, Abitbol, Vered, Amiot, Aurélien, Bouguen, Guillaume, Dib, Nina, Fumery, Mathurin, Pariente, Benjamin, Carbonnel, Franck, Peyrin-Biroulet, Laurent, Simon, Marion, Viennot, Stéphanie, and Bouhnik, Yoram
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- 2020
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44. Efficacy of Tumor Necrosis Factor Antagonist Treatment in Patients With Refractory Ulcerative Proctitis
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Nachury, Maria, Boschetti, Gilles, Flourié, Bernard, Danion, Pauline, Savoye, Guillaume, brazier, Franck, Loreau, Julien, Beaugerie, Laurent, Sokol, Harry, Nion-Larmurier, I., Bourrier, A., Landman, C., Lefèvre, J., Chafai, N., Bouta, Najima, Funakoshi, Natalie, Pineton de Chambrun, Guillaume, Amiot, Aurélien, Bouguen, Guillaume, Viennot, Stéphanie, Altwegg, Romain, Louis, Edouard, Collins, Michael, Fumery, Mathurin, Poullenot, Florian, Armengol, Laura, Buisson, Anthony, Abitbol, Vered, Laharie, David, Seksik, Philippe, Nancey, Stéphane, Blanc, Pierre, Bouhnik, Yoram, Pariente, Benjamin, and Peyrin-Biroulet, Laurent
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- 2020
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45. Monitoring a Combination of Calprotectin and Infliximab Identifies Patients With Mucosal Healing of Crohn’s Disease
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Dreesen, Erwin, Baert, Filip, Laharie, David, Bossuyt, Peter, Bouhnik, Yoram, Buisson, Anthony, Lambrecht, Guy, Louis, Edouard, Oldenburg, Bas, Pariente, Benjamin, Pierik, Marieke, van der Woude, C. Janneke, D’Haens, Geert, Vermeire, Séverine, and Gils, Ann
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- 2020
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46. Letter: Should ulcerative colitis be monitored more or less invasively?
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Laharie, David, primary
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- 2024
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47. Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study
- Author
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Peyrin-Biroulet, Laurent, primary, Allegretti, Jessica R., additional, Rubin, David T., additional, Bressler, Brian, additional, Germinaro, Matthew, additional, Huang, Kuan-Hsiang (Gary), additional, Shipitofsky, Nicole, additional, Zhang, Hongyan, additional, Wilson, Rebbecca, additional, Han, Chenglong, additional, Feagan, Brian G., additional, Sandborn, William J., additional, Panés, Julian, additional, Hisamatsu, Tadakazu, additional, Lichtenstein, Gary R., additional, Sands, Bruce E., additional, Dignass, Axel, additional, Abrahamovych, Orest, additional, Afanasieva, Halyna, additional, Aitova, Lilia, additional, Altintas, Engin, additional, Altwegg, Romain, additional, Andreev, Pavel, additional, Aomatsu, Kazuki, additional, Augustyn, Monika, additional, Balestrieri, Paola, additional, Begun, Jakob, additional, Brunatto, Luciana, additional, Bulgheroni, Diego, additional, Bunkova, Elena, additional, Cabello, Mercedes, additional, Cao, Qian, additional, Caprioli, Flavio, additional, Cerqueira, Rute, additional, Chen, Baili, additional, Chen, Chou-Chen, additional, Chen, Chou-Pin, additional, Chiu, Cheng-Tang, additional, Choi, Chang Hwan, additional, Cicala, Michele, additional, Datsenko, Olena, additional, Dewint, Pieter, additional, Domenech, Eugeni, additional, Dutré, Joris, additional, Duvall, George, additional, Fernandez, Juan, additional, Filip, Rafal, additional, Fogel, Ronald, additional, Fowler, Sharyle, additional, Fujii, Toshimitsu, additional, Fukata, Masayuki, additional, Furumoto, Yohei, additional, Gasbarrini, Antonio, additional, Gawdis-Wojnarska, Beata, additional, Gilletta, Cyrielle, additional, Gionchetti, Paolo, additional, Goldin, Eran, additional, Golovchenko, Oleksandr, additional, Gonciarz, Maciej, additional, Gonen, Can, additional, Segura, Gaston Gonzalez, additional, Gridnyev, Oleksii, additional, Gyokeres, Tibor, additional, Hébuterne, Xavier, additional, Hedin, Charlotte, additional, Hellström, Per, additional, Hilmi, Ida Normiha, additional, Horný, Ivo, additional, Horvat, Gyula, additional, Hoshi, Namiko, additional, Hrdlicka, Ludek, additional, Ishihara, Shunji, additional, Ivanishyn, Olha, additional, Jang, Byung Ik, additional, Junior, Odery, additional, Kagaya, Takashi, additional, Kanmura, Shuji, additional, Karakina, Marina, additional, Katsuhiko, Nakai, additional, Kierkus, Jaroslaw, additional, Kim, Hyo Jong, additional, Kim, Tae-Oh, additional, Kim, Young-Ho, additional, Kiss, Gyula G., additional, Klaus, Jochen, additional, Kleczkowski, Dariusz, additional, Klopocka, Maria, additional, Kobayashi, Taku, additional, Kobielusz-Gembala, Iwona, additional, Koo, Ja Seol, additional, Kopon, Adam, additional, Kravchenko, Tetiana, additional, Kudo, Masatoshi, additional, Kwon, Kwang An, additional, Lago, Paula, additional, Laharie, David, additional, Lawrance, Ian, additional, Leszczyszyn, Jaroslaw, additional, Li, Yan, additional, Lukas, Milan, additional, Maaser, Christian, additional, Maemoto, Atsuo, additional, Marusawa, Hiroyuki, additional, McBride, Matthew, additional, Mendu, Shoba, additional, Miheller, Pal, additional, Miyabayashi, Hideharu, additional, Mohl, Wolfgang, additional, Moore, Gregory, additional, Motoya, Satoshi, additional, Murali, Narayanachar, additional, Naem, Mohammed, additional, Nakajima, Koichi, additional, Nakamoto, Yasunari, additional, Nancey, Stéphane, additional, Neto, Joaquim, additional, Onizawa, Michio, additional, Ono, Yohei, additional, Osada, Taro, additional, Osipenko, Marina, additional, Owczarek, Danuta, additional, Patel, Bhaktasharan, additional, Patel, Kamal, additional, Petrova, Elina, additional, Poroshina, Elena, additional, Portela, Francisco, additional, Prystupa, Lyudmyla, additional, Rivero, Monserrat, additional, Roblin, Xavier, additional, Romatowski, Jacek, additional, Rydzewska, Grazyna, additional, Saibeni, Simone, additional, Sakuraba, Hirotake, additional, Samaan, Mark, additional, Schultz, Michael, additional, Schulze, Joerg, additional, Sedghi, Shahriar, additional, Seidler, Ursula, additional, Shin, Sung Jae, additional, Stanislavchuk, Mykola, additional, Stokesberry, David, additional, Suzuki, Takayoshi, additional, Taguchi, Hiroki, additional, Tankova, Lyudmila, additional, Thin, Lena, additional, Tkachev, Alexander, additional, Torrealba, Leyanira, additional, Tsarynna, Nataliia, additional, Tulassay, Zsolt, additional, Ueo, Tetsuya, additional, Valuyskikh, Ekaterina, additional, Vasilevskaya, Olga, additional, Viamonte, Manuel, additional, Wei, Shu-Chen, additional, Weisshof, Roni, additional, Wojcik, Katarzyna, additional, Ye, Byong Duk, additional, Yen, Hsu-Heng, additional, Yoon, Hyuk, additional, Yoshida, Kosuke, additional, Yurkiv, Andriy, additional, Zaha, Osamu, additional, and Zhan, Qiang, additional
- Published
- 2023
- Full Text
- View/download PDF
48. Bariatric Surgery in Patients With Inflammatory Bowel Disease: A Case-Control Study from the GETAID
- Author
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Reenaers, Catherine, de Roover, Arnaud, Kohnen, Laurent, Nachury, Maria, Simon, Marion, Pourcher, Guillaume, Trang-Poisson, Caroline, Rajca, Sylvie, Msika, Simon, Viennot, Stéphanie, Alttwegg, Romain, Serrero, Mélanie, Seksik, Philippe, Peyrin-Biroulet, Laurent, Picon, Laurence, Bourbao Tournois, Céline, Gontier, Renaud, Gilletta, Cyrielle, Stefanescu, Carmen, Laharie, David, Roblin, Xavier, Nahon, Stéphane, Bouguen, Guillaume, Carbonnel, Franck, Attar, Alain, Louis, Edouard, and Coffin, Benoît
- Published
- 2021
- Full Text
- View/download PDF
49. Efficacy of Induction Therapy With Calcineurin Inhibitors in Combination With Ustekinumab for Acute Severe Ulcerative Colitis
- Author
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Veyrard, Pauline, Pellet, Gauthier, Laharie, David, Nachury, Maria, Juillerat, Pascal, and Roblin, Xavier
- Published
- 2023
- Full Text
- View/download PDF
50. Altered sleep quality is associated with Crohn’s disease activity: an actimetry study
- Author
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Bazin, Thomas, Micoulaud Franchi, Jean-Arthur, Terras, Nathalie, Taillard, Jacques, Laharie, David, Zerbib, Frank, and Philip, Pierre
- Published
- 2020
- Full Text
- View/download PDF
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