865 results on '"Huang, Zhi-Shu"'
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2. Disrupting the protein-protein interaction network of Hsp72 inhibits adipogenic differentiation and lipid synthesis in adipocytes
3. Identification of sanguinarine as c-MYC transcription inhibitor through enhancing the G-quadruplex-NM23-H2 interactions
4. Synergistic anticancer activity of HSP70 and HSF1 inhibitors in colorectal cancer cells: A new strategy for combination therapy
5. Design, synthesis and structure-activity relationship of novel 2-pyrimidinylindole derivatives as orally available anti-obesity agents
6. Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells
7. Regulation of VEGF gene expression by bisacridine derivative through promoter i-motif for cancer treatment
8. Constructing triazole-modified quinazoline derivatives as selective c-MYC G-quadruplex ligands and potent anticancer agents through click chemistry
9. Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism
10. Development of a fluorescent chemical probe with the ability to visualize nascent phase-separated stress granules
11. Syntheses and evaluation of acridone derivatives as anticancer agents targeting Kras promoter i-motif structure
12. Regulation of c-Kit gene transcription selectively by bisacridine derivative through promoter dual i-motif structures
13. Xanthone sulfonamide derivatives-A novel series of α-glucosidase inhibitors with different inhibitory types
14. Dual-color imaging of DNA and RNA simultaneously with an aggregation/monomer-based deep-red fluorescent probe
15. L‐aspartate ameliorates diet‐induced obesity by increasing adipocyte energy expenditure.
16. 9-Bromo-2,3-diethylbenzo[de]chromene-7,8-dione (MSN54): A novel non-intercalative topoisomerase II catalytic inhibitor
17. Syntheses and evaluation of acridone-naphthalimide derivatives for regulating oncogene PDGFR-β expression
18. New Therapeutic Method for Alleviating Damage of Acute Kidney Injury Through BCL-2 Gene Promoter I-Motif.
19. Efficient and rational development of a new fluorescent probe specific for RNA G-quadruplex imaging in cells
20. Recent advances in fluorescent probes for G-quadruplex nucleic acids
21. A drug-like imidazole-benzothiazole conjugate inhibits malignant melanoma by stabilizing the c-MYC G-quadruplex
22. Discovery of a promising agent IQZ23 for the treatment of obesity and related metabolic disorders
23. Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors
24. Pyridocarbazole alkaloids from Ochrosia borbonica: lipid-lowering agents inhibit the cell proliferation and adipogenesis of 3T3-L1 adipocyte via intercalating into supercoiled DNA
25. Bouchardatine suppresses rectal cancer in mice by disrupting its metabolic pathways via activating the SIRT1-PGC-1α-UCP2 axis
26. Syntheses and evaluation of new Quinoline derivatives for inhibition of hnRNP K in regulating oncogene c-myc transcription
27. Development of Novel N‑Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde Group.
28. Mulberry Diels-Alder-type adducts from Morus alba as multi-targeted agents for Alzheimer's disease
29. Synthesis and evaluation of 1,2,3,4-tetrahydro-1-acridone analogues as potential dual inhibitors for amyloid-beta and tau aggregation
30. Tuning the selectivity of a commercial cyanine nucleic acid dye for preferential sensing of hybrid telomeric G-quadruplex DNA
31. Synthesis, cytotoxicity and structure-activity relationship of indolizinoquinolinedione derivatives as DNA topoisomerase IB catalytic inhibitors
32. Design, synthesis and biological evaluation of novel bouchardatine analogs as potential inhibitors of adipogenesis/lipogenesis in 3T3-L1 adipocytes
33. Identification of small molecules capable of regulating conformational changes of telomeric G-quadruplex
34. Synthesis of carbazole derivatives containing chalcone analogs as non-intercalative topoisomerase II catalytic inhibitors and apoptosis inducers
35. Discovery of Ingenane Diterpenoids from Euphorbia hylonoma as Antiadipogenic Agents
36. Interaction of Quindoline derivative with telomeric repeat–containing RNA induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2
37. Curcusone C induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2
38. Synthesis and evaluation of 7-substituted-5,6-dihydrobenzo[c]acridine derivatives as new c-KIT promoter G-quadruplex binding ligands
39. Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment
40. Analogues of xanthones——Chalcones and bis-chalcones as α-glucosidase inhibitors and anti-diabetes candidates
41. Targeting ATP-binding site of WRN Helicase: Identification of novel inhibitors through pocket analysis and Molecular Dynamics-Enhanced virtual screening
42. Syntheses and antibacterial activity of soluble 9-bromo substituted indolizinoquinoline-5,12-dione derivatives
43. Development of an engineered carbazole/thiazole orange conjugating probe for G-quadruplexes
44. Divergent Fluorinations of Vinylcyclopropanes: Ring‐Opening 1,5‐Hydrofluorination and Ring‐Retaining 1,2‐Difluorination
45. Design, synthesis and biological evaluation of 4-anilinoquinazoline derivatives as new c-myc G-quadruplex ligands
46. Accurate high-throughput identification of parallel G-quadruplex topology by a new tetraaryl-substituted imidazole
47. Blocking the binding of WT1 to bcl-2 promoter by G-quadruplex ligand SYUIQ-FM05
48. Complicated behavior of G-quadruplexes and evaluating G-quadruplexes' ligands in various systems mimicking cellular circumstance
49. A simple structural modification to thiazole orange to improve the selective detection of G-quadruplexes
50. Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5′-UTR RNA G‑Quadruplexes.
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