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284 results on '"Bosc R"'

4. Adherence to tumor board decisions and its impact on survival in older women with breast cancer

Author

Serrano, A. Gonzalez, primary, Corsin, L., additional, Benderra, M.A., additional, Boutin, E., additional, Assaf, E., additional, Belkacemi, Y., additional, Lagrange, J.L., additional, Bosc, R., additional, Bigorie, V., additional, Caillet, P., additional, Brain, E., additional, Rollot-Trad, F., additional, Canouï-Poitrine, F., additional, Paillaud, E., additional, and Laurent, M., additional

Published
2023
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6. Impact of Post-Mastectomy Radiotherapy on Cosmesis and Quality of Life after Deep Inferior Epigastric Perforator Flap Breast Reconstruction: A Single Institution Experience

Author

Mahé, M., primary, Bosc, R., additional, Loganadane V, G., additional, Grellier, N., additional, Billon, R., additional, Dao, T.H., additional, Debbi, K., additional, Ouidir, N., additional, Schwall, C., additional, To, N.H., additional, Beaussart, P., additional, Cherif, M.A., additional, Assaf, E., additional, Li, X., additional, Wang, S., additional, Rida, H., additional, Werkoff, G., additional, Boukhobza, C., additional, Hersant, B., additional, and Belkacemi, Y., additional

Published
2023
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27. Amélioration des pratiques en pathologie mammaire : organisation régionale de relecture par télépathologie dans le cadre du groupe SENOPATH

Author

Caverivière, P., primary, Gordien, K., additional, Quintyn-Ranty, M.-L., additional, Mery, E., additional, Jamme-Lallemand, M., additional, Wuithier, P., additional, Palasse, J., additional, Reyre, J., additional, Laborie, V., additional, Maisongrosse, V., additional, Despax, B., additional, Rolland, V., additional, Jacob, M., additional, Bosc, R., additional, Escourrou, G., additional, Bauvin, E., additional, Manenc, J.-L., additional, Roché, H., additional, and Lacroix-Triki, M., additional

Published
2013
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31. Apport des PCR ciblées et de la métagénomique 16S pour la détection des streptocoques béta-hémolytiques dans les dermohypodermites bactériennes nécrosantes-fasciites nécrosantes

Author

Kouby, F., primary, Hua, C., additional, Gomart, C., additional, Rodriguez, C., additional, Bernigaud, C., additional, Lavaud, J., additional, Gricourt, G., additional, Desmontant, V., additional, Costes, B., additional, Tazi, A., additional, Bosc, R., additional, De Prost, N., additional, Botterel, F., additional, Woerther, P.-L., additional, Chosidow, O., additional, and Decousser, J.-W., additional

Published
2019
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33. Preuve de concept du rôle d’un portage oropharyngé et périnéal dans un cas de fasciite nécrosante à streptocoque du groupe B sans porte d’entrée cutanée

Author

Charpentier, C., primary, Kouby, F., additional, Hua, C., additional, Darty, M., additional, Bosc, R., additional, De Prost, N., additional, Sbidian, E., additional, Gomart, C., additional, Woerther, P.-L., additional, Tazi, A., additional, Decousser, J.-W., additional, and Chosidow, O., additional

Published
2018
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36. Regional Nodal Irradiation (RNI) in the Sentinel Lymph Node Biopsy (SLNB) Era: Comparison of Radiation Therapy (RT) Techniques that Involve Axillary Nodal Levels I-IV

Author

Loganadane V, G., primary, Colson-Durand, L., additional, ghith-Neji, S., additional, Grellier, N., additional, Benchemsi, S. Mouafik, additional, To, N.H., additional, Jmour, O., additional, Pons, P., additional, Bosc, R., additional, Dao, T.H., additional, Totobenazara, J.L., additional, Fayolle-Campana, M., additional, and Belkacemi, Y., additional

Published
2018
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39. Use of the retrograde limb of the internal mammary vein to avoid venous congestion in DIEP flap breast reconstruction: Further evidences of a reliable and time-sparing procedure

Author

La Padula S., Hersant B., Noel W., Niddam J., Hermeziu O., Bouhassira J., Bosc R., Meningaud J. P., La Padula, S., Hersant, B., Noel, W., Niddam, J., Hermeziu, O., Bouhassira, J., Bosc, R., and Meningaud, J. P.

Abstract

Aim: Venous congestion is a common cause of DIEP flap failure. When identified intraoperatively, an additional venous anastomosis can improve the venous outflow and prevent flap failure. The aim of this study was to assess if the retrograde limb of the internal mammary vein (IMV) could be considered a good recipient vessel to be used when persistent flap congestion is present, and a second venous anastomosis is required. Patients and methods: A retrospective study was conducted in 74 patients who had undergone DIEP flap breast reconstruction. Patients were classified into two groups: SVA (single venous anastomosis) and DVA (dual venous anastomosis). In the SVA group (n = 38), the IMV antegrade limb was used for venous drainage. A single DIEV (Deep Inferior Epigastric Vein) was anastomosed to the superior arm of the IMV. In the DVA group (n = 36), both the antegrade (superior) and retrograde (inferior) stumps of the IMV were used, connecting the larger DIEV to the antegrade IMV and the other DIEV or the SIEV (Superficial Inferior Epigastric Vein) to the IMV retrograde limb. Results: No venous congestion or flap loss was observed when two venous anastomoses were performed using both the IMV antegrade and retrograde limbs (P = 0.3271). In the DVA group, no major complication occurred (P = 0.0453). Operative explorations were significantly reduced in the DVA group (P = 0.0242). Conclusion: These findings suggest that when an additional venous outflow is required, the use of the IMV retrograde limb may help to avoid flap venous congestion. © 2016 Wiley Periodicals, Inc. Microsurgery 36:447–452, 2016.

Published
2016

40. Pathogen identification by shotgun metagenomics of patients with necrotizing soft‐tissue infections.

Author

Rodriguez, C., Jary, A., Hua, C., Woerther, P.‐L., Bosc, R., Desroches, M., Sitterlé, E., Gricourt, G., De Prost, N., Pawlotsky, J.‐M., Chosidow, O., Sbidian, E., and Decousser, J.‐W.

Subjects
METAGENOMICS, BACTERIAL DNA, DRUG resistance in microorganisms, ANAEROBIC bacteria, PASTEURELLA multocida
Abstract

Summary: Background: Necrotizing soft‐tissue infections (NSTIs) are life threatening, requiring broad‐spectrum antibiotics. Their aetiological diagnosis can be limited by poor performance of cultures and administration of antibiotics before surgery. Objectives: We aimed (i) to compare 16S‐targeted metagenomics (TM) and unbiased semiquantitative panmicroorganism DNA‐ and RNA‐based shotgun metagenomics (SM) with cultures, (ii) to identify patients who would best benefit from metagenomics approaches and (iii) to detect the microbial pathogens in surrounding non‐necrotic 'healthy' tissues by SM‐based methods. Methods: A prospective observational study was performed to assess the analytical performance of standard cultures, TM and SM on tissues from 34 patients with NSTIs. Pathogen identification obtained with these three methods was compared. Results: Thirty‐four necrotic and 10 healthy tissues were collected from 34 patients. The performance of TM was inferior to that of the other methods (P < 0·05), whereas SM performed better than standard culture, although the result was not statistically significant (P = 0·08). SM was significantly more sensitive than TM for the detection of all bacteria (P = 0·02) and more sensitive than standard culture for the detection of anaerobic bacteria (P < 0·01). There was a strong correlation (r = 0·71, Spearman correlation coefficient) between the semiquantitative abundance of bacteria in the culture and the bacteria‐to‐human sequence ratio in SM. Low amounts of bacterial DNA were found in healthy tissues, suggesting a bacterial continuum between macroscopically 'healthy' and necrotic tissue. Conclusions: SM showed a significantly better ability to detect a broader range of pathogens than TM and identify strict anaerobes than standard culture. Patients with diabetes with NSTIs appeared to benefit most from SM. Finally, our results suggest a bacterial continuum between macroscopically 'healthy' non‐necrotic areas and necrotic tissues. What's already known about this topic? Necrotizing soft‐tissue infections (NSTIs) are characterized by rapidly progressive necrosis of subcutaneous tissues and high mortality, despite surgical debridement combined with broad‐spectrum antibiotics.The spectrum of potentially involved pathogens is very large, and identification is often limited by the poor performance of standard cultures, which may be impaired by previous antibiotic intake.Metagenomics‐based approaches show promise for better identification of the pathogens that cause these infections, but they have not been evaluated in this medical context. What does this study add? Shotgun metagenomics (SM) showed higher sensitivity than 16S rRNA gene sequencing and a better ability than culture to detect anaerobic bacteria. As a result, a significant proportion of infections with bacteria, such as Pasteurella multocida or Clostridium perfringens, were detected only by SM.SM bacterial quantification enabled better detection of low amounts of bacterial DNA from macroscopically 'healthy' tissue, suggesting a subclinical infectious extension. What is the translational message? The high analytical performance of SM shown in this study should allow its future implementation for the diagnosis of necrotizing fasciitis, complementing or replacing routine methods.The large amount of data, including additional information on antimicrobial resistance, virulence profiles and metabolic adaptation of the pathogens, will improve microbiological documentation.Our results will improve our understanding of infectious pathophysiology in the future, leading to potentially better medical care. Linked Comment: Moitinho‐Silva et al. Br J Dermatol 2020; 183:10. Plain language summary available online Respond to this article [ABSTRACT FROM AUTHOR]

Published
2020
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41. Comparaison de deux techniques d’irradiation locorégionale à l’ère du ganglion sentinelle

Author

Loganadane, G., primary, Colson-Durand, L., additional, Ghith-Neji, S., additional, Grellier-Adedjouma, N., additional, Mouafik Benchemsi, S., additional, To, N.-H., additional, Jmour, O., additional, Pons, P., additional, Bosc, R., additional, Dao, T.H., additional, Totobenazara, J.L., additional, Fayolle-Campana, M., additional, and Belkacémi, Y., additional

Published
2018
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47. Ex vivo estimation of cementless acetabular cup stability using an impact hammer

Author

Michel, Adrien, Bosc, R, Sailhan, F., Vayron, R., Haiat, Guillaume, Laboratoire de Modélisation et Simulation Multi Echelle (MSME), Université Paris-Est Marne-la-Vallée (UPEM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Lemaire, Thibault, and Centre National de la Recherche Scientifique (CNRS)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Université Paris-Est Marne-la-Vallée (UPEM)

Subjects
[SPI.MECA.BIOM] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph], [SPI.MECA.BIOM]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2016

48. Le réseau de pathologistes de Midi-Pyrénées. Bilan à 10 ans

Author

Gordien, K., primary, Rochaix, P., additional, Reyre, J., additional, Wuithier, P., additional, Palasse, J., additional, Caveriviere, P., additional, Hounieu, H., additional, Bosc, R., additional, Marson, V., additional, Siani-Wembou, V., additional, Boudat, A.M., additional, Anzieu, B., additional, Musso-Rigal, C., additional, Jamme-Lallemand, M., additional, Faure, P., additional, Brouchet, A., additional, Selves, J., additional, Bauvin, E., additional, and Brousset, P., additional

Published
2017
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50. In vitro evaluation of the acetabular cup primary stability by impact analysis

Author

Michel, A., Bosc, R., Mathieu, V., Hernigou, P., Haiat, G., Laboratoire de Modélisation et Simulation Multi Echelle (MSME), Université Paris-Est Marne-la-Vallée (UPEM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Université Paris-Est Marne-la-Vallée (UPEM), and Lemaire, Thibault

Subjects
[SPI.MECA.BIOM] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph], [SPI.MECA.BIOM]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2015

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