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318 results on '"Berardi, F."'

1. OC.16.6: APPLICATION OF MACHINE LEARNING MODEL-3P TO PREDICT PORTAL HYPERTENSION IN PATIENT WITH HEPATOCELLULAR CARCINOMA

Author

Soleri, M., primary, Berardi, F., additional, Bertazzoni, A., additional, Fortunato, M., additional, Ceriani, R., additional, Colapietro, F., additional, Pugliese, N., additional, Masetti, C., additional, Torzilli, G., additional, Pedicini, V., additional, Poretti, D., additional, Rimassa, L., additional, Comito, T., additional, De Nalda, A. Lleo, additional, Aghemo, A.M.G., additional, and De Nicola, S., additional

Published
2024
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7. Sigma 2 receptor expression levels in blood and bladder from healthy and bladder cancer cattle

Author

RUSSO, VALERIA, Inglese, C, AVALLONE, LUIGI, ROPERTO, FRANCO PEPPINO, Abate, C, Zizzo, N, Munday, Js, Berardi, F, Colabufo, Na, ROPERTO, SANTE, Russo, Valeria, Inglese, C, Avallone, Luigi, Roperto, FRANCO PEPPINO, Abate, C, Zizzo, N, Munday, J, Berardi, F, Colabufo, Na, and Roperto, Sante

Abstract

The expression of sigma-2 receptor (S2R) was assayed in blood and bladder samples from healthy cattle and in blood and bladder of cattle with deltapapillomavirus-associated urothelial tumors. Samples of bladder from cattle with neoplasia had significantly higher S2R than samples of bladder from healthy cattle (95% CI 0.31-0.82, P

Published
2017

8. Stability of the Dirac cone in artificial graphene formed in quantum wells: a computational many-electron study

Author

Kylanpaa I., Berardi F., Rasanen E., Garcia-Gonzalez P., Rozzi C.A., Rubio A., Academy of Finland, European Research Council, Ministerio de Economía y Competitividad (España), Eusko Jaurlaritza, European Commission, Tampere University, Department of Physics, and Research group: Quantum Control and Dynamics

Subjects
Dirac materials, Artificial grapheme, 114 Physical sciences, Stability properties
Abstract

We carry out a comprehensive computational study on the stability of the Dirac cone in artificial graphene realized in nanopatterned quantum wells. Our real-space approach allows us to vary the size, shape, and positioning of the quantum dots in the hexagonal lattice. We compare the (noninteracting) single-particle calculations to density-functional studies within both local-density approximation and meta-generalized-gradient approximation. Furthermore, the density-functional results are compared against numerically precise path-integral quantum Monte Carlo calculations. As a whole, our results indicate high stability of the Dirac bands against external parameters, which is reassuring for further experimental investigations., This work has been supported by the Academy of Finland (grant agreement No. 267686) and the Nordic Innovation through its Top-Level Research Initiative (Project No. P-13053), the European Research Council (ERC-2015-AdG-694097), the Spanish Ministry of Economy and Competitiveness (grants FIS2013-46159-C3-1-P, and MAT2014-53432-C5-5-R), the Basque Country Government (Grupos Consolidados IT-578-13), FP7 MC-IIF MODENADYNA (grant agreement No. 623413), and COST Action MP1306 (EUSpec). PGG acknowledges financial support from the Spanish Ministry of Economy and Competitiveness, through the 'María de Maeztu' Programme for Units of Excellence in R&D (MDM-2014-0377).

Published
2016
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21. [Italian Consensus Conference on drug-eluting stents]

Author

Indolfi, C, Berardi, F, Bolognese, L, Danzi, Gb, Galassi, Ar, Della Grazia, E, Montinaro, A, Paloscia, L, Vassanelli, Corrado, Bartorelli, A, Klugmann, S, Petronio, As, Scherillo, M, and Marzilli, M.

Subjects
Sirolimus, Clinical Trials as Topic, Drug Carriers, Paclitaxel, Coronary Stenosis, Humans, Stents
Published
2004

22. Consensus Conference italiana sui 'drug-eluting stents'

Author

Indolfi, C, Berardi, F, Bolognese, L, Danzi, Gb, Galassi, Alfredo, Della Grazia, E, Montinaro, A, Paloscia, L, Vassanelli, C, Bartorelli, A, Klugmann, S, Petronio, As, Scherillo, M, and Marzilli, M.

Subjects
drug-eluting stent
Published
2004

23. Guidelines for resuscitation in the delivery room of extremely preterm infants

Author

Verlato, G., Gobber, D., Drago, D., Chiandetti, L., Drigo, P., Allergo, A., Battaglia, M. A., Dalla Barba, B., Filippone, M., Gamba, P., Paola Lago, Magarotto, M., Ortolani, E., Orzali, A., Pesavento, R., Salvadori, S., Sartor, M., Simioni, P., Tormena, F., Trafojer, U., Trevisanuto, D., Viafora, C., Zaggia, C., Zaramella, P., Zacchello, F., Ambrosini, A., Berardi, F., Cerutti, R., Ciullo, R., Toffoli, J., Di Lenardo, L., Fais, G., Giorgino, F., Grella, P., Grismondi, G. L., Guarnieri, E., Minucci, D., Nardelli, G., Pellizzari, P., Polonia, P., Ponchia, R., Siliotti, F., Serpotta, G., Suma, V., Trivellato, P., Pitton, M., Tambuscio, B., and Petolillo, M.

Subjects
Male, medicine.medical_specialty, Resuscitation, Gestational Age, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, 030225 pediatrics, Intensive care, medicine, Humans, Infant, Very Low Birth Weight, Intensive care medicine, Fetal Viability, Resuscitation Orders, business.industry, Extremely preterm, Delivery Rooms, Delivery room, Palliative Care, Infant, Newborn, Gestational age, Bioethics, Prognosis, Cardiopulmonary Resuscitation, Survival Rate, Italy, Pediatrics, Perinatology and Child Health, Female, Neurology (clinical), business, 030217 neurology & neurosurgery, Infant, Premature
Abstract

Ethical problems related to intensive care of extremely preterm newborns of ≤ 25 weeks' gestational age and at risk of disability have been extensively debated. The Bioethical Committee of the Department of Paediatrics of the University Hospital of Padua organized and started a multidisciplinary group to release guidelines to help staff facing problems related to prematurity. The vitality limit, survival, outcome, and ethical aspects were analyzed. Consequently, we suggest the following: at 22 weeks' gestational age, the deliverance of comfort care only; at 23 weeks, in the presence of detectable vital signs, the practice of immediate intubation, respiratory support, and a reassessment of the neonatal conditions; and at 24 weeks, the provision of intubation, ventilatory support, and cardiovascular resuscitation. If the clinical age and anamnestic gestational age are different, we proceed according to the more advanced one. The importance of providing parents with correct information and the role of comfort care are outlined. ( J Child Neurol 2004;19:31—34).

Published
2004

32. 11C-Labelling of N-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]arylcarboxamide Derivatives and Evaluation as Potential Radioligands for PET imaging of Dopamine D3 Receptors

Author

Turolla, E, Matarrese, M, Belloli, S, Moresco, R, Simonelli, P, Todde, S, Fazio, F, Magni, F, Kienle, M, Leopoldo, M, Berardi, F, Colabufo, N, Lacivita, E, Perrone, R, TUROLLA, ELIA ANNA, MORESCO, ROSA MARIA, SIMONELLI, PASQUALE, TODDE, SERGIO CAMILLO, FAZIO, FERRUCCIO, MAGNI, FULVIO, KIENLE, MARZIA DONATELLA, Colabufo, NA, Perrone, R., Turolla, E, Matarrese, M, Belloli, S, Moresco, R, Simonelli, P, Todde, S, Fazio, F, Magni, F, Kienle, M, Leopoldo, M, Berardi, F, Colabufo, N, Lacivita, E, Perrone, R, TUROLLA, ELIA ANNA, MORESCO, ROSA MARIA, SIMONELLI, PASQUALE, TODDE, SERGIO CAMILLO, FAZIO, FERRUCCIO, MAGNI, FULVIO, KIENLE, MARZIA DONATELLA, Colabufo, NA, and Perrone, R.

Abstract

The selective dopamine D(3) receptor ligands N-4-[4-[(2,3-dichlorophenyl)piperazin-1-yl]butyl]1-methoxy-2-naphthalencarboxamide (1) and N-4-[4-[(2,3-dichlorophenyl)piperazin-1-yl]butyl]-7-methoxy-2-benzofurancarboxamide (2) were labeled with (11)C (t(1/2) = 20.4 min) as potential radioligands for the noninvasive assessment of the dopamine D(3) neurotransmission system in vivo with positron emission tomography (PET). The radiosynthesis consisted in an O-methylation of the des-methyl precursors N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1-hydroxy-2-naphthalenecarboxamide (3) and N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-7-hydroxy-2-benzofurancarboxamide (4) with [(11)C]methyl iodide using tBuOK/HMPA and KOH/DMSO, respectively. The radiotracers [(11)C]1 and [(11)C]2 were obtained in 35 min with over 99% radiochemical purity, 74 +/- 37 GBq/mumol of specific radioactivity, 13% and 26% radiochemical yield (EOB, decay-corrected). Distribution studies in rats demonstrated that the new tracers [(11)C]1 and [(11)C]2 cross the blood-brain barrier and localize in the brain. However, the kinetics of cerebral uptake did not reflect the regional expression of the D(3) receptors. Despite their in vitro pharmacological profile, [(11)C]1 and [(11)C]2 do not display an in vivo behavior suitable to image D(3) receptor expression using PET.

Published
2005

33. Distribution of sigma receptors in EMT-6 cells: Preliminary biological evaluation of PB167 and potentials for in vivo PET

Author

Colabufo, N, Berardi, F, Contino, M, Fazio, F, Matarrese, M, Moresco, R, Niso, M, Perrone, R, Tortorella, V, Colabufo, NA, FAZIO, FERRUCCIO, MORESCO, ROSA MARIA, Tortorella, V., Colabufo, N, Berardi, F, Contino, M, Fazio, F, Matarrese, M, Moresco, R, Niso, M, Perrone, R, Tortorella, V, Colabufo, NA, FAZIO, FERRUCCIO, MORESCO, ROSA MARIA, and Tortorella, V.

Abstract

Sigma(1) and sigma(2) receptors have been detected in many tissues and are highly expressed in several tumour cell lines from various tissues. The high level of expression observed for sigma receptors and their involvement in cell proliferation and apoptosis has led to the development of several sigma ligands in order to obtain a molecular probe for in-vivo diagnostic imaging techniques such as positron emission tomography (PET) and single photon emission computerized tomography (SPECT). The EMT-6 cells implanted in mice were a good model for evaluating the proliferation of solid tumours by in-vivo PET. Moreover, we developed the sigma ligand PB167, a cyclohexylpiperazine derivative, previously evaluated for sigma(2) receptor affinity and activity in standard protocols. The related results encouraged us to verify if this compound could be developed as a radiotracer for in-vivo PET in order to visualize sigma(2) receptors expressed in EMT-6 cells when implanted in mice. This perspective was thought to be favourable because PB167 bears a methoxy substituent on the tetraline nucleus, an easy point for (11)C labelling. The aims of this preliminary study were both to assess the relative distribution of sigma(1) and sigma(2) receptors in EMT-6 cells and to verify if PB167 could be developed as a sigma(2) radiotracer for in-vivo PET. The results showed that both sigma(1) and sigma(2) receptors were overexpressed in EMT-6 cells and that the ligand PB167 can be positively considered for radiosynthesis preparation in order to suitably visualize sigma(2) receptors by the in-vivo PET technique and correlate their presence to tumour proliferation.

Published
2005

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