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IntroductionThe COVID-19 pandemic significantly impacted the mental health of individuals with chronic conditions such as Wilson’s Disease (WD). This study investigates stress, anxiety, depression, quality of life, cognitive function, vaccination rates, infection rates, and perceptions related to the pandemic and vaccines among WD patients.MethodsThe study analyzed COVID-19 perceptions and vaccine attitudes of 62 adult WD patients enrolled in the international multisite WD Registry. A subgroup of 33 participants completed a series of mental health scales. The effect of working essentially, income loss, wellness activity initiation, and infection of COVID-19 during the pandemic was observed.ResultsResults indicate that, overall, the pandemic did not exacerbate anxiety or cognitive function in WD patients but did lead to increased depression among essential workers. Patients experiencing income loss exhibited higher levels of stress and anxiety. Despite these challenges, WD patients showed high vaccination rates and positive attitudes towards vaccines.DiscussionThe findings underscore the significant impact of the pandemic on the mental health of WD patients.

Measurement(s) Motivation • Emotional Well-being • Socioeconomic Indicator • Culture • Cultural Diversity Technology Type(s) survey method • digital curation Sample Characteristic - Organism Homo sapiens Sample Characteristic - Location Australia • Austria • Bolivia • Brazil • Bulgaria • Canada • Chile • China • Colombia • Czech Republic • Germany • Hong Kong • India • Israel • Italy • Japan • Kenya • Lebanon • Mexico • The Netherlands • New Zealand • Nigeria • Pakistan • Peru • The Philippines • Portuguese Republic • Romania • Russia • Saudi Arabia • Senegal • Serbia • Singapore • Slovak Republic • South Korea • Spain • Sweden • Thailand • Turkey • Uganda • Ukraine • United Kingdom • United States of America

Greater “emotional fit” with one's cultural group is often associated with positive psychological and relational outcomes. However, the few empirical studies on this link have been limited to the comparison of Anglo-Western, independent, and East Asian, interdependent cultural contexts. In the current paper, we conceptually replicated findings from three studies on the link between emotional fit and well-being in Anglo-Western and East Asian contexts, using different methods and more comprehensive samples. Moreover, we expanded emotional fit research to the understudied Mediterranean region, characterized by an emphasis on “honor” and a distinct blend of independence and interdependence. We collected data from N = 3,097 participants from 12 countries and asked participants to report their emotional experience in 10 hypothetical situations and to rate their well-being in different domains. Our results largely replicated established positive links between emotional fit and well-being in the Anglo-West and East-Asia, as i) experiencing more culturally valued emotions (from which we infer cultural fit) was linked to better general well-being; ii) actual, calculated emotional fit in relationship-focused situations predicted better relational well-being; and iii) only in East Asia calculated emotional fit in culturally central contexts predicted psychological well-being and thriving. Our exploratory analyses on the Mediterranean region showed a non-homogenous pattern: while general well-being was consistently most strongly predicted by the intensity of disengaging emotions, relational and psychological well-being were differentially predicted by calculated emotional fit in relationship-focused situations across different Mediterranean sub-regions. The current work consolidates insights into how our well-being is shaped by the interplay between culture and emotional fit and strengthens evidence that there may be ‘universalism without uniformity’.

The sense of feeling at home by people ‘on the move’ was inquired through an adaptation of the homemaking approach. Two groups of people who make their living by working in agricultural sites (internally mobile seasonal agricultural workers and internationally displaced migrant workers) were reached out to examine associations between feeling at home, social interactions, perceived degradation, and subjective well-being. Results showed that both worker groups (seasonal and displaced workers) felt at home despite precarious working and living conditions. Expectedly, feeling at home was predicted significantly by social interactions with others; however, the type of interactions also determined the direction of the effects. While within-group interaction (binding ties) predicted feeling at home positively, across-groups interaction (bridging ties) predicted it negatively for both groups. Additionally, perceived degradation and subjective well-being moderated the effect of feeling at home partially: the effect emerged for a cross-groups but not for within-group interactions. In conclusion, the notion of binding and bridging ties could help to attain an increased explanatory power rather than contact theory alone in understanding the patterns of feeling at home.

The COVID-19 pandemic heightened risk factors for suicide globally. Using prominent sociocultural theories of suicide, we investigated whether the COVID-19 pandemic affected suicide rates differently across demographic groups and regions in the United States of America. In Study 1, we found that after 2020 suicide rates increased especially among young Black and Alaskan Native populations. Conditional process analyses were conducted to shed light on racial disparities in the temporal impact of unemployment on suicide from 2018 to 2021. The results showed that suicides among younger Asians and Blacks were affected by the surge in unemployment, whereas Whites, especially the older population, benefitted from the increased unemployment. In Study 2, we explored the regional variation in the temporal associations between suicide, unemployment, and depression across the 50 U.S. states from 2019 to 2021 taking into account pre-pandemic between-state conditions. Multilevel regression analyses showed that urbanism (characterized by low firearm proportion, high income, high cultural looseness, and high population density) but not social integration (characterized by low social capital, high collectivism, and high southerness), partially explained the regional variation in the temporal pattern of suicide rates. We also found that in states with already high depression levels, the temporal increase in depression predicted increases in suicide from 2019 to 2021, whereas it had minimal impact in states with low average depression. We emphasize the need for future theories to consider longitudinal designs and highlight two key takeaways: (1) the pandemic reshaped racial disparities in suicide, and (2) the temporal effects brought by the national crisis on suicide patterns depended on existing between-state differences.

Scholars have been working through multiple avenues to address longstanding and entrenched patterns of global and racial exclusion in psychology and academia more generally. As part of the Society for Personality and Social Psychology’s efforts to enhance inclusive excellence in its journals, the Anti Colorism/Eurocentrism in Methods and Practices (ACEMAP) task force worked to develop recommendations and resources to counteract racism and global exclusion in standard publication practices. In this paper, the task force describes a structure and process we developed for conducting committee work that centers marginalized perspectives while mitigating cultural taxation. We then describe our recommendations and openly accessible resources (e.g., resources for inclusive reviewing practices, writing about constraints on generalizability, drafting a globally inclusive demographic information survey, inclusive citation practices, and improving representation among editorial gatekeeping positions; recommendations and resource links are provided in Table 3). These recommendations and resources are both (a) tailored for a particular set of journals at a particular time and (b) useful as a foundation that can be continually adapted and improved for other journals and going forward. This paper provides concrete plans for readers looking to enhance inclusive excellence in their committee work, authorship, reviewing, and/or editing.

Summary: Ultra-high chip power densities that are expected to surpass 1-2kW/cm2 in future high-performance systems cannot be easily handled by conventional cooling methods. Various emerging cooling methods, such as liquid cooling via microchannels, thermoelectric coolers (TECs), two-phase vapor chambers, and hybrid cooling options have been designed to efficiently remove heat from high-performance processors. However, selecting the optimal cooling solution for a given chip and determining the optimal cooling parameters for that solution to achieve high efficiency are open problems. These problems are, in fact, computationally expensive because of the massive space of possible solutions. To address this design challenge, this article introduces a deep learning-based cooling design optimization flow that rapidly and accurately converges to the optimal cooling solution as well as the optimal cooling parameters for a given chip floorplan and its power profile.

The worldwide spread of a new coronavirus (SARS-CoV-2) since December 2019 has posed a severe threat to individuals' well-being. While the world at large is waiting that the released vaccines immunize most citizens, public health experts suggest that, in the meantime, it is only through behavior change that the spread of COVID-19 can be controlled. Importantly, the required behaviors are aimed not only at safeguarding one's own health. Instead, individuals are asked to adapt their behaviors to protect the community at large. This raises the question of which social concerns and moral principles make people willing to do so. We considered in 23 countries (N = 6948) individuals' willingness to engage in prescribed and discretionary behaviors, as well as country-level and individual-level factors that might drive such behavioral intentions. Results from multilevel multiple regressions, with country as the nesting variable, showed that publicized number of infections were not significantly related to individual intentions to comply with the prescribed measures and intentions to engage in discretionary prosocial behaviors. Instead, psychological differences in terms of trust in government, citizens, and in particular toward science predicted individuals' behavioral intentions across countries. The more people endorsed moral principles of fairness and care (vs. loyalty and authority), the more they were inclined to report trust in science, which, in turn, statistically predicted prescribed and discretionary behavioral intentions. Results have implications for the type of intervention and public communication strategies that should be most effective to induce the behavioral changes that are needed to control the COVID-19 outbreak.

Despite the rising number of men and women in counter-stereotypical roles, it is rare for men to serve as primary caregivers in families with dependent children. In two studies, we examined how British men and women perceive and emotionally react to primary caregiver (vs. breadwinner) fathers, whether their perceptions and reactions are contingent upon individual differences in masculine honor endorsement, and the potential mediators in these relationships. Results showed that both men and women perceived the primary caregiver fathers more positively – warmer and not less competent – than the primary breadwinner fathers, yet endorsement of masculine honor ideals increased men’s (but not women’s) tendency to attribute less positive emotions (e.g., proud and satisfied) and more negative emotions (e.g., ashamed and resentful) to the primary caregiver (vs. breadwinner) fathers. Mediated moderation analyses showed that for men with high masculine honor orientation, their less positive and more negative emotional attributions were driven by perceived loss of reputation among male friends, whereas for men with low masculine honor orientation, their more positive and less negative emotional attributions were driven by perceived gain of wife’s and children’s admiration. By shifting the focus to men’s individual differences and motives, these findings offer nuanced explanations for why some men may feel eager about serving as caregiver fathers, whereas others may feel reluctant to do so.

HIV +Elite and Viremic controllers (EC/VCs) are able to control virus infection, perhaps because of host genetic determinants. We identified 16% (21 of 131) EC/VCs with CD4 +T cells with resistance specific to R5-tropic HIV, reversed after introduction of ccr5. R5 resistance was not observed in macrophages and depended upon the method of T cell activation. CD4 +T cells of these EC/VCs had lower ccr2 and ccr5 RNA levels, reduced CCR2 and CCR5 cell-surface expression, and decreased levels of secreted chemokines. T cells had no changes in chemokine receptor mRNA half-life but instead had lower levels of active transcription of ccr2 and ccr5, despite having more accessible chromatin by ATAC-seq. Other nearby genes were also down-regulated, over a region of ~500 kb on chromosome 3p21. This same R5 resistance phenotype was observed in family members of an index VC, also associated with ccr2/ccr5 down-regulation, suggesting that the phenotype is heritable.

Individuals’ cultural tendencies of horizontal/vertical individualism and collectivism interact with their dispositional traits and contextual factors to shape social interactions. A key dispositional trait is social value orientation (SVO), a general tendency toward competition (proself) vs. cooperation (prosocial) in social exchanges. The present study (N = 1032) explored the relationship between SVO and personal cultural tendencies of horizontal/vertical individualism and collectivism in two different cultural settings, the United States (a vertical individualist setting) and South Korea (a vertical collectivistic setting). We hypothesized that each value orientation would be associated with the congruent personal cultural tendency across settings. We further hypothesized that this association would be specific to the context, so that SVO would play a more relevant role where the cultural theme was less dominant. Results indicated that, across contexts, proself individuals endorsed vertical individualistic values more strongly than prosocial individuals. Conversely, prosocial individuals endorsed horizontal collectivistic values more strongly than proself individuals. In addition, the effect of SVO was different in the two cultural contexts. Compared to proself individuals, prosocial individuals endorsed horizontal collectivism more strongly in the United States context, and horizontal individualism less strongly in the Korea context. Theoretical implications and limitations of the findings, as well as directions for future work are discussed.

Cultures differ in many important ways, but one trait appears to be universally valued: prosociality. For one’s reputation, around the world, it pays to be nice to others. However, recent research with American participants finds that evaluations of prosocial actions are asymmetric—relatively selfish actions are evaluated according to the magnitude of selfishness but evaluations of relatively generous actions are less sensitive to magnitude. Extremely generous actions are judged roughly as positively as modestly generous actions, but extremely selfish actions are judged much more negatively than modestly selfish actions (Klein & Epley, 2014). Here we test whether this asymmetry in evaluations of prosociality is culture-specific. Across 7 countries, 1,240 participants evaluated actors giving various amounts of money to a stranger. Along with relatively minor cross-cultural differences in evaluations of generous actions, we find cross-cultural similarities in the asymmetry in evaluations of prosociality. We discuss implications for how reputational inferences can enable the cooperation necessary for successful societies.

HIV +Elite and Viremic controllers (EC/VCs) are able to control virus infection, perhaps because of host genetic determinants. We identified 16% (21 of 131) EC/VCs with CD4 +T cells with resistance specific to R5-tropic HIV, reversed after introduction of ccr5. R5 resistance was not observed in macrophages and depended upon the method of T cell activation. CD4 +T cells of these EC/VCs had lower ccr2 and ccr5 RNA levels, reduced CCR2 and CCR5 cell-surface expression, and decreased levels of secreted chemokines. T cells had no changes in chemokine receptor mRNA half-life but instead had lower levels of active transcription of ccr2 and ccr5, despite having more accessible chromatin by ATAC-seq. Other nearby genes were also down-regulated, over a region of ~500 kb on chromosome 3p21. This same R5 resistance phenotype was observed in family members of an index VC, also associated with ccr2/ccr5 down-regulation, suggesting that the phenotype is heritable.