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目的 探索缺血性脑血管病患者出院后3个月二级预防药物依从性及其影响因素。 方法 选取2014年1月-2018年11月任丘康济新图医院神经内科住院的急性脑梗死和TIA患者，调查其住院期间及出院后3个月服用二级预防药物的依从性，采用多因素logistic回归分析出院后3个月患者药物依从性的影响因素。 结果 4151例入组患者中，3个月随访时二级预防药物总体依从性为78.8%，在二级预防药物种类中依从性分别为抗血小板药物89.3%、降压药物87.5%、降脂药物86.9%、降糖药物79.3%、抗凝药物56.0%。多因素logistic回归分析显示，已婚（OR 1.589，95%CI 1.304～1.936，P＜0.001）、卒中病史（OR 1.225，95%CI 1.037～1.447，P=0.017）、糖尿病病史（OR 0.570，95%CI 0.463～0.701，P＜0.001）、发病前抗凝药物使用（OR 0.192，95%CI 0.060～0.619，P=0.006）、出院时二级预防药物种类数（OR 0.841，95%CI 0.736～0.960，P=0.010）为二级预防药物依从性的独立影响因素。 结论 已婚、卒中病史、糖尿病病史、发病前抗凝药物使用及出院时二级预防药物种类数是二级预防药物依从性的独立影响因素。 Abstract: Objective To analyze the adherence of secondary prevention drugs within 3 months after discharge and related influencing factors in patients with ischemic cerebrovascular disease. Methods The patients with acute cerebral infarction and TIA hospitalized in Department of Neurology of Renqiu Kangji Xintu Hospital from January 2014 to November 2018 were included in the retrospective analysis. The adherence of drugs during hospitalization and 3 months after discharge were analyzed. Multivariate logistic regression analysis was used to determine the influencing factors of drug adherence. Results A total of 4151 patients were included in this study. The total adherence rate of secondary prevention drugs at 3 months after discharge was 78.8%, and that of all kinds of secondary prevention drugs were as follows: antiplatelet drugs was 89.3%, antihypertensive drugs was 87.5%, lipid-lowering drugs was 86.9% and hypoglycemic drugs was 79.3% and anticoagulants was 56.0%. Multivariate logistic regression analysis showed that being married (OR 1.589, 95%CI 1.304-1.936, P

文章提出一种可以传输42个轨道角动量（OAM）模式的环形光子晶体光纤,该光纤由中心空气孔、环形高折射率层以及包层构成,其中包层是由方形空气孔与圆形空气孔共同组成。利用有限元法对其进行仿真分析,仿真结果表明,这种结构在1.55μm处可以将简并模间的有效折射率差提高到3.45×10-3,从而大大减小模式间的耦合,所有模式的色散值均较小,例如HE2,1模式的色散只有53.29ps/（nm·km）。此外,光能量主要集中在环形高折射率区域内,且环形区域大小可灵活设计。

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: The development of steroid-induced osteonecrosis of the femoral head is a complex process involving multiple mechanisms. There is still no standard therapeutic drug for early intervention of this disease. Current studies have shown that baicalein has various pharmacological activities such as regulating lipid metabolism, bone metabolism, apoptosis and anti-oxidative stress, which provides an idea for the prevention and treatment of steroid-induced osteonecrosis of the femoral head. OBJECTIVE: To observe the preventive effect of baicalein against steroid-induced osteonecrosis of the femoral head and to investigate its possible mechanism. METHODS: Thirty-six 10-week-old male Sprague-Dawley rats were randomly divided into three groups (n=12 per group): blank control group, model group, and baicalein intervention group. In the model group and baicalein intervention group, intraperitoneal lipopolysaccharide and intramuscular injection of methylprednisolone sodium succinate were performed for modeling, while normal saline was used as a substitute for the modeling drug in the blank control group. Baicalein 300 mg/kg was administered by gavage (once a day for 6 weeks) at the time of initial intramuscular glucocorticoid injection in the baicalein intervention group, and baicalein was replaced by normal saline in the other two groups. The serum level of malondialdehyde in rats was detected at 2 weeks of the experiment. Blood lipid indicators and bone formation metabolic markers were detected at 6 weeks of the experiment, the histomorphometric changes of the femoral head were analyzed by hematoxylin-eosin staining, anti-tartaric acid phosphatase staining and TUNEL staining, and the femoral head was subjected to Micro-CT scanning and three-dimensional reconstruction of the bone in order to analyze the alterations of bone tissue structure and parameters. RESULTS AND CONCLUSION: The serum levels of malondialdehyde, triglyceride, β-collagen type I carboxy-terminal peptide were increased and the serum levels of bone specific alkaline phosphatase and pre-collagen type I amino-terminal peptide were decreased in the model group compared with the blank control group (P < 0.05). The serum level of malondialdehyde decreased in the baicalein intervention group compared with the model group (P < 0.05), but there was no significant difference between the baicalein intervention group and blank control group (P > 0.05). The serum level of triglyceride was higher in the baicalein intervention group than the blank control group (P < 0.05), but had no significant difference between the baicalein intervention group and model group (P > 0.05). There were also no significant differences in the levels of bone specific alkaline phosphatase and β-collagen type I carboxy-terminal peptide between the baicalein intervention group and the other two groups (P > 0.05). The serum level of the baicalein intervention group was lower in the baicalein intervention group than the blank control group (P < 0.05) but had no significant difference between the baicalein intervention group and model group (P > 0.05). Histomorphological analysis of the femoral head showed that the rate of bone empty lacuna, osteoclast counting and cell apoptosis rate in the femoral head of model group rats were significantly higher than those of the other two groups (P < 0.05). There was a significant increase in the number of adipocytes in the bone marrow cavity of the femoral head, bone trabeculae were thinned and sparsely arranged with more disruptions in the continuity. The incidence of osteonecrosis was higher in the model group (75%) than in the baicalein intervention group (25%; bilateral and unilateral exact significance results were both 0.05). There was also an increase in the number of adipocytes in the bone marrow cavity of the femoral head in the baicalein intervention group, and the trabecular changes were roughly similar to those in the model group. Micro-CT results showed that bone volume fraction, trabecular thickness, trabecular number, and bone mineral density decreased and trabecular separation increased in the model group compared with the blank control group (P < 0.05). Overall significant bone mass loss was observed in the model group. Bone tissue parameters in the baicalein intervention group were significantly improved than those in the model group, which were reflected in bone volume fraction, trabecular thickness and trabecular separation (P < 0.05), and trabecular number and bone mineral density had no significant difference between the baicalein intervention group and blank control group (P > 0.05). Although baicalein failed to significantly ameliorate dyslipidemia and promote bone formation in rats with steroid-induced osteonecrosis of the femoral head, it could reduce the incidence of steroid-induced osteonecrosis of the femoral head by reducing oxidative stress damage, decreasing cell apoptosis, inhibiting osteoclasts, suggesting its effectiveness in the early prevention of steroid-induced osteonecrosis of the femoral head. [ABSTRACT FROM AUTHOR]

Using the daily temperature, sunshine, precipitation and other meteorological element data from the Wuhai Meteorological Bureau from 2009 to 2018, as well as the Hansen wine grape experiment data, the correlation between the sugar-acid ratio of wine grapes and the meteorological factors in each growth period was analyzed, and a fitting model between the meteorological factors and the sugar-acid ratio was established. The results showed that the meteorological conditions during the growth of wine grapes had certain effects on the sugar-acid ratio after grapes matured, and the meteorological conditions from fruit formation to picking were most significant. The average minimum temperature in September,≥10 ℃ accumulated temperature from the entire flowering period to the picking period, sunshine hours from the color transition period to the maturity period, and hydrothermal coefficient from late July to early August had a significant impact on the sugar-acid ratio, with correlation coefficients ranging from 0. 6 to 0. 8, and all had passed the test α = 0. 05 significance test. A statistical model for meteorological factors and sugar-acid ratio was established by comprehensively considering factors such as temperature, water and heat, and sunlight. The fitting effect was good, providing a basis for field management and quality improvement of wine grapes. [ABSTRACT FROM AUTHOR]

Copyright of Mycosystema is the property of Mycosystema Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Feed Industry is the property of Liaoning Provincial Institute of Agricultural Mechanization and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Curriculum ideological and political education is a new concept of comprehensive education to implement the fundamental task of moral education in higher education in the new era. Under the background of new agricultural science, promoting the ideological and political construction of agricultural master’s courses will inevitably require agricultural universities to find the right position, take moral education as the foundation, and strive to cultivate a high-quality talent team that knows agriculture, values agriculture and loves agriculture. This paper put forward suggestions on the path of ideological and political construction of agricultural master’s curriculum from four aspects of improving the ideological and political system of college curriculum and establishing a long-term operation mechanism, improving teachers’ ideological and political teaching and research ability, stimulating students’ initiative and participation, and exploring new methods of ideological and political education and teaching, in order to provide strong talent supports for agricultural and rural modernization and rural revitalization. [ABSTRACT FROM AUTHOR]

Copyright of Food & Machinery is the property of Food & Machinery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Mine Automation is the property of Industry & Mine Automation Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Henan Agricultural Sciences is the property of Editorial Board of Journal of Henan Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Feed Research is the property of Editorial Board of Feed Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Anhui Agricultural Sciences is the property of Journal of Anhui Agricultural Sciences Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The research progress of carbon capture, utilization, and storage(CCUS) technology, especially referring to the application research of magnesiumfunctional materials such as MgO and Mg/Al hydrotalc让e in C02 capture and carbon resource conversion was reviewed・ Magnesium-based materials have diverse applications due to their unique physical, chemical properties and structures. This review introduces the modification works of researchers on magnesium・based materials and summarizes the future development trend of CCUS technology and magnesium・base(l functional materials. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Preventive Veterinary Medicine / Zhongguo Yufang Shouyi Xuebao is the property of Chinese Journal of Preventive Veterinary Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Chinese Journal of Inorganic Analytical Chemistry / Zhongguo Wuji Fenxi Huaxue is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Southwest China Journal of Agricultural Sciences is the property of Editorial Department of Southwest China Journal of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Oilfield Chemistry is the property of Sichuan University, Oilfield Chemistry Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Characteristics and spatial distribution of perfluorinated compounds (PFCs) pollution in agricultural water of suburban Beijing typical rivers were investigated in 30 water samples collected from the agricultural water of Liangshui River in Tongzhou District and Ciwei River-Xiaoqing River in Fangshan District. The species and concentration of PFCs in water were determined and studied using ultra-high performance liquid chromatography-tandem mass spectrometry, and occurrence characteristics and possible sources of PFCs were analyzed. Finally, an ecological risk assessment was performed. More PFCs were detected at low levels in the agricultural water environment of typical rivers in suburban Beijing. Eleven types of PFCs were detected in Liangshui River. The total PFC concentration range was 0-62.7 ng·L-1, and the main PFCs were perfluorobutanoic acid, perfluorohexanoic acid, and perfluorooctanoic acid. Twenty one PFCs were detected in Ciwei River-Xiaoqing River. The total PFC concentration range was 0-93.1 ng · L-1, and the main PFCs were perfluoropentanoic acid, perfluoroundecanoic acid, and perfluorododecanesulfonate. The results revealed great upstream pollution of PFCs from agricultural water in typical rivers of suburban Beijing. Pollution originated mainly from sewage treatment plant effluent discharge and surface runoff. The ecological risk assessment showed that the concentrations of PFCs in water bodies did not reach levels that are harmful to the ecological environment. [ABSTRACT FROM AUTHOR]

Copyright of Atomic Energy Science & Technology is the property of Editorial Board of Atomic Energy Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of International General Practice is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Pediatric Surgery is the property of Journal of Clinical Pediatric Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

With fresh cut rose flowers as the test materials, taking traditional natural dye plant Buddleja officinalis Maxim.as dye materials, the influences of dye concentration, dyeing temperature, dyeing time and pH of dye solution on the dyeing effect of natural rose immortal flowers dyed by the natural yellow pigment of B.officinalis were studied by using the orthogonal test method,, in order to lay the foundation for the further development and utilization of natural dye plants B.officinalis and the plant dyeing process of immortal flowers. The results showed that the optimum process for dyeing rose immortal flowers with natural yellow pigment of B.officinalis was as follows: pH of dye solution 7, dyeing time 7 h, dyeing temperature 35 °C, dye concentration 14 g/L. Under the best dyeing process, rose immortal flowers was orange, natural in shape, soft in texture, full in color, so it had good ornamental value. [ABSTRACT FROM AUTHOR]

: 【Objective】The objective is to explore the feasibility of using WAVE bioreactor for Escherichia coli strain amplification after the strain recovered without using shake flask and expanding the seed cells into a disposable XDR bioreactor for plasmid production, as well as to establish a process for GMP grade plasmids production on a fully disposable upstream platform.【Method】Optimizing the carbon to nitrogen ratio for E.coli growth, basic culture medium and supplementary culture media that do not contain any animal derived components were screened.Directly inoculating E.coli strain to shake flasks and WAVE bioreactor after strain thawing, the feasibility of low-density innoculation was investigated, and the differences of E.coli strain amplification in shake flask and in WAVE bioreactor was compared. The expansion process of E.coli strains in WAVE bioreactor was established, and then the seed cells were amplified into a 50L XDR bioreactor for plasmid production.【Result】Compared with traditional LB medium, the optimized basic medium without any animal origin ingredients increased the maximum OD600 and plasmid yield by 43% and 77% respectively. After E.coli strain thawing, WAVE25 bioreactor was directly inoculated with a low density of 1∶1 000-1∶8 000. The specific growth rate of the E.coli strain in WAVE25 bioreactor reached (0.65±0.065)/h. WAVE bioreactor showed better capability for controlling process parameters, and the seed cells from one WAVE bioreactor directly inoculated 50- 200 L production fermentor for plasmid production. The maximum OD600 and plasmid titer reached 53 OD and 340 mg/L respectively, the specific plasmid yield reached 6.42 mg/L/OD600, which was more than 2 times higher than that of conventional plasmid process. The proportion of supercoiled plasmids reached 90% at upstream harvest, which made it possible for downstream two-step chromatography purification of plasmids.【Conclusion】In conclusion, a full disposable production platform has been established to directly amplify E. coli strain through WAVE bioreactor, and the seed cells from one WAVE bioreactor can be used to inoculate 50-200 L production fermentor for GMP grade plasmid production. [ABSTRACT FROM AUTHOR]

This research aims to study the source, spatial distribution characteristics and ecological risks of diuron in the coastal waters of the Yangtze River Estuary and Shanghai, water samples from 24 stations in the coastal waters of the Yangtze River Estuary, Hengsha Island （inland） waters and the waters near the Yangtze River Estuary Chinese sturgeon reserve were collected from October to November 2021, and the content of diuron in the surface water samples of each station was analyzed by solid phase extraction and high performance liquid chromatography tandem mass spectrometry. According to the test results, the mass concentration of diuron was detected in the water samples of 24 stations in three different regions. Among them, the detection range of diuron mass concentration at 10 stations along the Yangtze River Estuary in Shanghai was 182.43-439.38 ng/L, and the detection rate was 100%. The detection range of diuron mass concentration at 9 stations in Hengsha Island （inland） water area is 83.48-369.25 ng/L, and the detection rate is 100%. The detection range of diuron mass concentration at 5 stations near the Chinese sturgeon reserve is 1.97-2.85 ng/L, and the detection rate is 100%. The spatial distribution of diuron is mainly affected by factors like water transport, ship maintenance, agricultural activities, tides and seawater dynamics. Besides, the ecological risk assessment shows that the coastal waters along the Yangtze River Estuary in Shanghai are potentially at medium risk. Farming areas in Hengsha inland waters are at medium risk, and the nearby waters of the Nature Reserve are at low risk. The results show that the environment in the coastal waters of the Yangtze River Estuary in Shanghai is being threatened by the diuron, especially in the major ports and docks along the Yangtze River Estuary in Shanghai as well as the agricultural areas and river intersections in the Hengsha Island area. Although it will not threaten the Chinese sturgeon reserve in the short run, it still deserves attention. [ABSTRACT FROM AUTHOR]

Copyright of Journal Of Sichuan University (Natural Sciences Division) / Sichuan Daxue Xuebao-Ziran Kexueban is the property of Editorial Department of Journal of Sichuan University Natural Science Edition and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)