The leaves, twigs and ripe fruits of Magnolia grandis (Hu & W.C.Cheng) V.S.Kumar, growing wild in Ha Giang Province of Vietnam, were hydrodistilled to obtain essential oils which had the respective average yields of 0.09%, 0.25% and 0.62% (v/w), calculated on a dry weight basis. The oils were analyzed using gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Major components of these three oil samples were: α-pinene (11.8%), linalool (15.4%) and (E)-β-caryophyllene (10.7%) (leaf oil); α-pinene (42.8%) and β-pinene (23.7%) (twig oil); α-pinene (52.2%) (ripe fruit oil). The essential oils from leaves showed stronger inhibitory effects on the seven tested microorganism strains than those from twigs and ripe fruits. To our best knowledge, this is the first time that information on essential oils of M. grandis leaves, twigs and ripe fruits is reported. [ABSTRACT FROM AUTHOR]