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Purpose: To evaluate the optical quality of Acrysof Restor SN6AD1 refractive–diffractive +3.00 D and Lentis Mplus LS-312 nonrotational symmetric +3.00 D aspheric multifocal intraocular lenses (IOLs) and analyze the effect of tilt and decentration. Setting: University of Valencia, Valencia, and University of Murcia, Murcia, Spain. Design: Experimental study. Methods: An artificial model eye was used to measure wavefront aberrations of both IOL models. The modulation transfer function (MTF) and point-spread function (PSF) were calculated for a 5.0 mm pupil and under 5 situations: centered, 0.2 mm and 0.4 mm decentered, and 2 degrees and 4 degrees tilted. Results: The refractive–diffractive IOL had the highest MTF values at all spatial frequencies. Similarly, the PSF was worse for the refractive–diffractive IOL. The MTFs for the refractive–diffractive IOL decreased when the IOL was decentered or tilted, being more robust for tilting than decentration. The MTFs for the nonrotational symmetric IOL were similar under all testing conditions. Cutoff frequencies for the refractive–diffractive IOL were stable over the range of tilting studied and comparable with the cutoff when the IOL was centered (approximately 50 cycles per degree [cpd]). When the IOL was decentered, the cutoff frequency decreased by approximately 40 cpd. The nonrotational symmetric IOL cutoff frequencies for misalignment and tilt were low (approximately 30 cpd) and similar under all conditions. Conclusions: The refractive–diffractive IOL provided better optical quality than the nonrotational symmetric IOL. Tilt and decentration had a significant impact on optical quality with both IOLs, being more severe with the nonrotational symmetric IOL. Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned. [ABSTRACT FROM AUTHOR]

Purpose: To compare visual acuity after bilateral implantation of 2 models of multifocal aspheric intraocular lenses (IOLs). Setting: Fernández-Vega Ophthalmological Institute, Oviedo, and University of Valencia, Valencia, Spain. Methods: Prospective study of patients who had bilateral implantation of an AcrySof ReSTOR SN6AD3 IOL (Group 1) or an Acri.LISA 366D IOL (Group 2). Six months postoperatively, binocular uncorrected and best corrected distance visual acuity, uncorrected-distance and best distance-corrected near visual acuity, best corrected intermediate visual acuity, and the defocus curve were measured in both IOL groups. Results: Group 1 comprised 36 eyes (18 patients) and Group 2, 40 eyes (20 patients). The mean binocular values in Group 1 and Group 2, respectively, were as follows: best corrected distance acuity, −0.05 ± 0.09 logMAR and −0.08 ± 0.08 logMAR (both approximately 20/20); best distance-corrected near acuity, −0.01 ± 0.16 logMAR and −0.05 ± 0.07 logMAR; best corrected intermediate acuity at 80 cm, 0.20 ± 0.18 logMAR (approximately 20/32) and 0.16 ± 0.13 logMAR (approximately 20/25) and at 60 cm, 0.16 ± 0.16 logMAR (approximately 20/25) and 0.18 ± 0.13 logMAR (approximately 20/25). There were no statistically significant between-group differences in visual acuity at any distance (P>.3). Defocus curves were similar between groups (2.00 to −5.00 diopters) (P>.26). Conclusions: The 2 multifocal aspheric IOL models gave similar and good high-contrast visual acuity at distance and near. Intermediate visual acuity, also comparable between IOL models, was better than published results of a spherical IOL model. [Copyright &y& Elsevier]