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The article offers information on regulatory science to promote access to intrauterine systems (IUS) for women in the U.S. Topics include the long-acting, reversible contraceptive (LARC) methods that include IUSs have been shown to be highly effective in preventing unintended pregnancy, and the IUS being a small T-shaped device that is placed in the uterus, providing an effective mode of long-term reversible contraception.