1. High prevalence of elevated haemoglobin A1C among adolescent blood donors: Results from a voluntary screening programme including 31,546 adolescents.
- Author
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Gore MO, Eason SJ, Ayers CR, Turer AT, Khera A, de Lemos JA, McGuire DK, and Sayers M
- Subjects
- Adolescent, Black or African American statistics & numerical data, Asian statistics & numerical data, Blood Pressure, Cholesterol metabolism, Cohort Studies, Cross-Sectional Studies, Diabetes Mellitus ethnology, Diabetes Mellitus metabolism, Female, Hispanic or Latino statistics & numerical data, Humans, Hypercholesterolemia epidemiology, Hypercholesterolemia ethnology, Hypercholesterolemia metabolism, Hypertension epidemiology, Male, Mass Screening, Prediabetic State ethnology, Prediabetic State metabolism, Prospective Studies, Rural Population, Sex Distribution, United States epidemiology, Urban Population, White People statistics & numerical data, Young Adult, Blood Donors, Diabetes Mellitus epidemiology, Glycated Hemoglobin metabolism, Prediabetic State epidemiology
- Abstract
More than 1 in 10 US adolescents have prediabetes or diabetes, and elevated glycosylated haemoglobin (HbA1C) in youth is associated with increased risk of death before the age of 55 years. We conducted a prospective, cross-sectional study of 31,546 consecutive volunteer blood donors, 16-19 years of age, who donated blood during school blood drives between 1 September 2011 and 21 December 2012 in Texas. In the overall cohort, the prevalence of elevated HbA1C was 11.5%, including 11.0% in the prediabetes range (HbA1C 5.7%-6.4%) and 0.5% in the diabetes range (HbA1C ⩾ 6.5%). The prevalence of elevated HbA1C was higher in boys compared with girls (15.7% vs. 7.9%, p < 0.001) and was especially high in racial/ethnic minorities (Blacks 32.7%, Asians 19.7%, Hispanics 13.1%) compared with Whites (8.0%, p < 0.001). There was a significant increase in total cholesterol and blood pressure across categories of increasing HbA1C in the overall cohort and stratified by sex and race/ethnicity. Blood donation programmes can serve as unique portals for health screening with potential for intervention in adolescents., (© The Author(s) 2015.)
- Published
- 2015
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