1. Identification of atypical scrapie in Canadian sheep.
- Author
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Mitchell GB, O'Rourke KI, Harrington NP, Soutyrine A, Simmons MM, Dudas S, Zhuang D, Laude H, and Balachandran A
- Subjects
- Animals, Blotting, Western, Canada epidemiology, Codon genetics, Goat Diseases epidemiology, Goat Diseases virology, Goats, Immunoblotting methods, PrPSc Proteins classification, PrPSc Proteins genetics, Prion Diseases diagnosis, Prion Diseases epidemiology, Prion Diseases veterinary, Prion Diseases virology, Prions genetics, Prions pathogenicity, Sheep, Sheep Diseases epidemiology, Sheep Diseases virology, United States, PrPSc Proteins pathogenicity, Scrapie epidemiology
- Abstract
Scrapie, a transmissible spongiform encephalopathy of sheep and goats, exists in most small ruminant-producing countries of the world. A novel form of this disease was recently recognized and is known by various names, including Nor98, Nor98-like, and atypical scrapie. Differing from classic scrapie in epidemiology, histopathology, and biochemical characteristics, atypical scrapie cases have been identified throughout Europe and in the United States. Enhanced scrapie surveillance efforts recently identified 3 cases of atypical scrapie in Canada.
- Published
- 2010
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