1. Approach to the patient with venous thromboembolism. Treatment with thrombolytic agents.
- Author
-
Sasahara AA, St Martin CC, Henkin J, and Barker WM
- Subjects
- Amino Acid Sequence, Fibrinolytic Agents therapeutic use, Follow-Up Studies, Humans, Incidence, Molecular Sequence Data, Plasminogen chemistry, Thromboembolism diagnosis, Thromboembolism epidemiology, Thrombophlebitis diagnosis, Thrombophlebitis drug therapy, Thrombophlebitis epidemiology, United States epidemiology, Urokinase-Type Plasminogen Activator chemistry, Thromboembolism drug therapy, Thrombolytic Therapy
- Abstract
This article reviews the different thrombolytic agents currently available and the different mechanisms by which they activate the body's fibrinolytic system. The discussion is confined to the approach to the patient with venous thromboembolism using the different thrombolytic agents. Data are presented supporting the use of thrombolytic therapy and its long-term benefits, especially in patients with pulmonary embolism. A substantial portion of this article is devoted to practical considerations involved in the administration of thrombolytic therapy.
- Published
- 1992