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Takano and Osaka (2018) tested the validity of the common view that Japanese are more collectivistic than Americans by reviewing empirical studies published mainly during recent two decades, and found that this common view was not supported by most of the reviewed studies. All the four commentaries on this review of ours shared with us the basic judgment that the common view is untenable. In this reply, we present arguments to resolve some doubts cast on our review, and then argue that situation is a key concept to investigate critical issues related to individualism and collectivism such as their dimensionality and distinction between societal level and individual level cultural difference. [ABSTRACT FROM AUTHOR]

It has been long believed that the Japanese are typical collectivists whereas Americans are typical individualists. To examine the validity of this common view, we formerly reviewed 15 empirical studies that compared Japanese and Americans regarding individualism/collectivism (I/C), and found that the overwhelming majority of those studies had not supported the common view (Takano & Osaka,). In this follow‐up, we reviewed 20 additional empirical studies (7 behavioral studies, 13 questionnaire studies), most of which had been published after the former review. When combined with the formerly reviewed 15 studies, 19 studies reported no clear difference, and 11 studies reported that Japanese were more individualistic than Americans. These 30 studies are inconsistent with the common view. Only 5 studies supported the common view, even when we included 3 studies whose validity was questionable. After it was formerly found that the common view was not supported empirically, a variety of alternative accounts were presented regarding the reason for this finding. We examined three major accounts in light of the reviewed studies and found that none of them was congruent with the empirical data. Thus, it seems to be reasonable to conclude that the common view is not valid. [ABSTRACT FROM AUTHOR]

T-wave alternans and QT dispersion were compared as predictors of the outcome of electrophysiologic study and arrhythmia-free survival in patients undergoing electrophysiologic evaluation. T-wave alternans was a highly significant predictor of these 2 outcome variables, whereas QT dispersion was not. [ABSTRACT FROM AUTHOR]

The aim of this study was to evaluate the effects of implemented control measures to reduce illness induced by Vibrio parahaemolyticus ( V. parahaemolyticus) in horse mackerel ( Trachurus japonicus), seafood that is commonly consumed raw in Japan. On the basis of currently available experimental and survey data, we constructed a quantitative risk model of V. parahaemolyticus in horse mackerel from harvest to consumption. In particular, the following factors were evaluated: bacterial growth at all stages, effects of washing the fish body and storage water, and bacterial transfer from the fish surface, gills, and intestine to fillets during preparation. New parameters of the beta-Poisson dose-response model were determined from all human feeding trials, some of which have been used for risk assessment by the U.S. Food and Drug Administration (USFDA). The probability of illness caused by V. parahaemolyticus was estimated using both the USFDA dose-response parameters and our parameters for each selected pathway of scenario alternatives: washing whole fish at landing, storage in contaminated water, high temperature during transportation, and washing fish during preparation. The last scenario (washing fish during preparation) was the most effective for reducing the risk of illness by about a factor of 10 compared to no washing at this stage. Risk of illness increased by 50% by exposure to increased temperature during transportation, according to our assumptions of duration and temperature. The other two scenarios did not significantly affect risk. The choice of dose-response parameters was not critical for evaluation of control measures. [ABSTRACT FROM AUTHOR]

Exporting unspliced human immunodeficiency virus type 1 (HIV-1) RNA from the nucleus to the cytoplasm, through an interaction between the viral regulatory Rev protein and Rev response element (RRE) RNA, is a critical step in the HIV-1 life-cycle. Disruption of either Rev or the RRE will completely inhibit HIV-1 replication. As such, a strategy for somatic gene therapy to treat HIV-1 infection by intracellular expression of an anti-HIV-1 Rev single chain variable fragment (SFv) and a ribozyme which specifically targets the RRE was developed. The anti-Rev D8SFv, which specifically targets the Rev activation domain, may be a key component of combination intracellular immunization, as it has been previously shown to potently inhibit Rev function, thereby inhibiting viral replication. In the present studies, different HIV-1 RRE region-specific hammerhead ribozymes were constructed and their anti-HIV-1 replication effects were assayed in diverse RNA polymerase (pol) II and III promoters and vector systems in cell culture. Utilizing this combination of an SFv and a ribozyme as a dual strategy to block HIV-1 replication, both at the protein and RNA level, data from these studies demonstrated that potent inhibition of HIV-1 replication can be achieved via this approach. Combination gene therapies hold promise, analogous to combination chemotherapeutic regimens, for the in vivo treatment of HIV-1 infections. [ABSTRACT FROM AUTHOR]

The article offers information on the technological innovations in the world and discusses the contribution of the U.S. Electrochemical Society (ECS) to the same. Topics discussed were advancement of the iPhone by Steve Jobs, developments in engineering and technology in Japan and the energy and environment projects. It also offers information on the Electrochemical Conference on Energy and the Environment by the ECS and the Chinese Society of Electrochemistry to be held in Shanghai, China.