1. Women with elevated blood pressure and stage 1 hypertension are at high risk for preeclampsia. A retrospective study at a tertiary facility in Japan.
- Author
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Shindo, Ryosuke, Aoki, Shigeru, Nakanishi, Sayuri, Obata, Soichiro, and Miyagi, Etsuko
- Subjects
HYPERTENSION epidemiology ,BLOOD pressure ,HYPERTENSION in pregnancy ,CARDIOLOGY ,CONFIDENCE intervals ,TERTIARY care ,RETROSPECTIVE studies ,DISEASE incidence ,PREECLAMPSIA ,RISK assessment ,PREGNANCY outcomes ,COMPARATIVE studies ,DESCRIPTIVE statistics ,ODDS ratio ,WOMEN'S health ,DISEASE complications - Abstract
Aim: In 2017, the American College of Cardiology (ACC) re‐defined hypertension (HT) as follows: elevated blood pressure (EBP), systolic blood pressure (SBP) 120–129 mmHg and diastolic blood pressure (DBP) <80 mmHg; stage 1 HT, SBP 130–139 mmHg or DBP 80–89 mmHg; and stage 2 HT: SBP ≥140 mmHg or DBP ≥90 mmHg. It is well known that women with stage 2 HT are at higher risk of preeclampsia and have poorer pregnancy and delivery outcomes. While there are few reports on the risk in women with EBP and stage 1 HT, and none from Japan. This study aimed to determine whether women in Japan with EBP and stage 1 HT are at risk of preeclampsia. Methods: In this single‐center retrospective study conducted in Japan, subjects were classified into stage 2 HT, stage 1 HT, EBP, and normal groups based on blood pressure measurements at the time of the first visit before 20 weeks of gestation. Women with a diagnosis of hypertension made before pregnancy were classified into the stage 2 HT group. We compared pregnancy and delivery outcomes, such as preeclampsia, between groups. Results: A total of 5129 cases (normal, n = 4283; EBP, n = 427; stage 1 HT, n = 303; stage 2 HT, n = 116) were included. Preeclampsia incidence rates were 2.7%, 5.6%, 10.6%, and 21.6%, respectively. The adjusted OR (95% CI) for preeclampsia incidence were 2.90 (1.81–4.66), 5.90 (3.87–9.20), and 13.80 (7.97–24.0), respectively. Conclusions: Women with EBP and stage 1 HT are at high risk of preeclampsia, similar to those with stage 2 HT. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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