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The article presents a study that analyzed the potential negative consequences of adding phosphorus-based fertilizers to immobilize lead in soil. Strong linear correlations were shown by soil-metal concentrations for antimony (Sb) and lead (Pb) from various surface soils taken from the firing ranges at all three sites in the U.S. Also examined was the mobility of Sb and arsenic (As) in leachate collected from columns of amended and unamended soils. The study revealed that arsenic concentrations are high in groundwater at approximately 30% of contaminated sites in the U.S.

Presents views on the advancement of diagnosis and treatment of ovarian cancer in the U.S. Challenges faced by medical professionals in treating women with ovarian cancer; Consideration of surgery as first-line intervention; Significance of chemotherapy as a key part of treatment for most women with ovarian cancer.

Objective: To review the current status of large phase academic clinical trials for women with ovarian cancer, address cross-cutting issues, and identify promising areas for future collaboration., Methods: In May 2009, the Gynecologic Cancer Intergroup, which represents 19 Cooperative Groups conducting trials for women with gynecologic cancer, and the US National Cancer Institute convened a Clinical Trials Planning Meeting., Results: The topics covered included the impact of new developments in cancer biology upon molecular targets and novel agents, pharmacogenomics, advances in imaging, the potential benefit of diet and exercise to reduce the risk of recurrence, academic partnership with industry, statistical considerations for phases 2 and 3 trials, trial end points, and symptom benefit and health-related quality-of-life issues. The clinical trials discussed spanned the spectrum of ovarian cancer from initial diagnosis, staging, and cytoreductive surgery to consolidation chemotherapy, and treatment of recurrent disease., Conclusions: Ongoing and effective collaboration with industry, government, and patients aims to ensure that the most important scientific questions can be answered rapidly. We encourage women with ovarian cancer and their oncologists to consider participation in the academic clinical trials conducted by the member groups of the Gynecologic Cancer Intergroup.

This features a presentation by Dr. Sidney Kaye on the occasion of the Milton Helpern Lecture at the annual meeting of the National Association of Medical Examiners near Fort Myers in Florida in 1989. The author experienced the "golden age" of forensic medicine as a student and associate of Dr. Alexander Gettler in the New York Medical Examiner's Office. He also worked with Dr. Rutherford Gradwohl in the St. Louis Police Department and was one of the founders of the American Academy of Forensic Sciences. He was the toxicologist in the Virginia medical examiners' system before moving to Puerto Rico. His discussion is a historical review of his experiences in developing forensic sciences.