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Background: The American Heart Association has defined a new metric of ideal cardiovascular health as part of its 2020 Impact Goals. We examined whether psychosocial factors in youth predict ideal cardiovascular health in adulthood., Methods and Results: Participants were 477 men and 612 women from the nationwide Cardiovascular Risk in Young Finns Study. Psychosocial factors were measured from cohorts 3 to 18 years of age at the baseline of the study, and ideal cardiovascular health was examined 27 years later in adulthood. The summary measure of psychosocial factors in youth comprised socioeconomic factors, emotional factors, parental health behaviors, stressful events, self-regulation of the child, and social adjustment of the child. There was a positive association between a higher number of favorable psychosocial factors in youth and greater ideal cardiovascular health index in adulthood (β=0.16; P<0.001) that persisted after adjustment for age, sex, medication use, and cardiovascular risk factors in childhood (β=0.15; P<0.001). The association was monotonic, suggesting that each increment in favorable psychosocial factors was associated with improvement in cardiovascular health. Of the specific psychosocial factors, a favorable socioeconomic environment (β=0.12; P<0.001) and participants' self-regulatory behavior (β=0.07; P=0.004) were the strongest predictors of ideal cardiovascular health in adulthood., Conclusions: The findings suggest a dose-response association between favorable psychosocial factors in youth and cardiovascular health in adulthood, as defined by the American Heart Association metrics. The effect seems to persist throughout the range of cardiovascular health, potentially shifting the population distribution of cardiovascular health rather than simply having effects in a high-risk population., (© 2015 American Heart Association, Inc.)

Objective: Diabetes is an increasingly important public health concern, but little is known about the contribution of psychological factors on diabetes risk. We examined whether personality is associated with risk of incident diabetes and diabetes-related mortality., Method: An individual-participant meta-analysis of 34,913 adults free of diabetes at baseline (average age 53.7 years, 57% women) from 5 prospective cohort studies from the United States and United Kingdom. Personality dimensions included extraversion, neuroticism, agreeableness, conscientiousness, and openness to experience based on the Five Factor Model., Results: During an average follow-up of 5.7 years, 1845 participants became diabetic. Of the 5 personality dimensions, only low conscientiousness was associated with an elevated diabetes risk (OR = 0.87, 95% CI = 0.82-0.91 per 1 standard deviation increment in conscientiousness). This association attenuated by 60% after adjustment for obesity and by 25% after adjustment for physical inactivity. Low conscientiousness was also associated with elevated risk of diabetes mortality (HR = 0.72, CI = 0.53-0.98 per 1 standard deviation increment in conscientiousness). Other personality traits were not consistently associated with diabetes incidence or mortality., Conclusions: Low conscientiousness-a cognitive-behavioral disposition reflecting careless behavior and a lack of self-control and planning-is associated with elevated risk of diabetes and diabetes-related mortality. The underlying mechanisms are likely to involve health behaviors, such as poor weight management, physical inactivity, and adherence to medical management recommendations.