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Hepatitis E is considered rare in the United States (US) despite its widespread occurrence in Asian and African countries. The objective of this study was to describe the characteristics of hepatitis E‐related pregnancies and acute‐on‐chronic liver failure and analyse trends for hepatitis E diagnosis among hospitalized patients in the US. We examined data from the 2010–2017 National Inpatient Sample from Healthcare Cost and Utilization Project to determine mortality, morbidity, pregnancy diagnoses, chronic liver disease diagnoses, and other conditions during hospitalization. Data were extracted for hospitalizations with hepatitis E as defined by ICD‐9 codes 070.43 and 070.53 and ICD‐10 code B17.2. Of 208,462,242 hospitalizations from 2010–2015, we identified 960 hepatitis E hospitalizations. The hospitalization rate of hepatitis E was 3.7 per 10 million in 2010 and 6.4 per 10 million in 2015 (β = 0.60, p = 0.011). From 2015 to 2017, the hospitalization appeared to increase with slope (β) of 0.50. Among those hospitalizations, 34 (4%) died and 85 (9%) had acute‐on‐chronic liver failure. Ninety‐five (10%) had a diagnosis of pregnancy, there were no reports of maternal or foetus/neonate deaths, but there was a high proportion of adverse events for both during hospitalization. Having a chronic liver disease was associated with hepatic coma diagnosis (OR = 10.94, p = 0.002). Although the hospitalization rate of hepatitis E in the US is low, it appears to be increasing over time. Further studies are necessary in order to conclude a causal association of hepatitis E with adverse events and mortalities in pregnancy and chronic liver disease in the US. [ABSTRACT FROM AUTHOR]

The military “theater distribution vehicle routing and scheduling problem” (TDVRSP) is associated with determining superior allocations of required flows of personnel and materiel within a defined geographic area of operation. A theater distribution system is comprised of facilities, installations, methods, and procedures designed to receive, store, maintain, distribute, and control the flow of material between exogenous inflows to that system and distribution to end-user activities and units within the theater. An automated system that can integrate multimodal transportation assets to improve logistics support at all levels has been characterized as a major priority and immediate need for the U.S. military services.This paper describes both the conceptual context, based in a flexible group theoretic tabu search (GTTS) framework, and the software implementation of a robust, efficient, and effective prescriptive generalized theater distribution methodology. This methodology evaluates and prescribes the routing and scheduling of multimodal theater transportation assets at the individual asset operational level to provide economically efficient time-definite delivery of cargo to customers. [Copyright &y& Elsevier]

Presents the highlights of the annual meeting of the American Epilepsy Society held in Philadelphia, Pennsylvania. Date of the event; Participant of the meeting; Program and activities of the congress; Theme of the convention.