1. Estimating effects of parents' cognitive and non-cognitive skills on offspring education using polygenic scores.
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Demange, Perline A., Hottenga, Jouke Jan, Abdellaoui, Abdel, Eilertsen, Espen Moen, Malanchini, Margherita, Domingue, Benjamin W., Armstrong-Carter, Emma, de Zeeuw, Eveline L., Rimfeld, Kaili, Boomsma, Dorret I., van Bergen, Elsje, Breen, Gerome, Nivard, Michel G., and Cheesman, Rosa
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PARENTS ,ASSORTATIVE mating ,PARENTAL influences ,FAMILY policy ,EDUCATIONAL outcomes - Abstract
Understanding how parents' cognitive and non-cognitive skills influence offspring education is essential for educational, family and economic policy. We use genetics (GWAS-by-subtraction) to assess a latent, broad non-cognitive skills dimension. To index parental effects controlling for genetic transmission, we estimate indirect parental genetic effects of polygenic scores on childhood and adulthood educational outcomes, using siblings (N = 47,459), adoptees (N = 6407), and parent-offspring trios (N = 2534) in three UK and Dutch cohorts. We find that parental cognitive and non-cognitive skills affect offspring education through their environment: on average across cohorts and designs, indirect genetic effects explain 36–40% of population polygenic score associations. However, indirect genetic effects are lower for achievement in the Dutch cohort, and for the adoption design. We identify potential causes of higher sibling- and trio-based estimates: prenatal indirect genetic effects, population stratification, and assortative mating. Our phenotype-agnostic, genetically sensitive approach has established overall environmental effects of parents' skills, facilitating future mechanistic work. Understanding how parents' cognitive and non-cognitive skills influence their children's educational trajectories is important for educational, family and economic policy. Here, the authors investigate parental influence on children's education using genetic approaches. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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