1. Bladder pain syndrome: validation of simple tests for diagnosis in women with chronic pelvic pain: BRaVADO study protocol.
- Author
-
Tirlapur, Seema A., Priest, Lee, Wojdyla, Daniel, and Khan, Khalid S.
- Subjects
BLADDER diseases ,PELVIC pain diagnosis ,CONFIDENCE intervals ,LONGITUDINAL method ,QUESTIONNAIRES ,DIAGNOSIS - Abstract
Background Bladder pain syndrome (BPS), a condition with no gold standard diagnosis, comprises of a cluster of signs and symptoms. Bladder filling pain and bladder wall tenderness are two basic clinical features, present in a high number of sufferers. This study will validate the performance of these simple tests for BPS in women with chronic pelvic pain (CPP). Methods/design We will conduct a prospective test validation study amongst women with unexplained CPP presenting to gynaecology outpatient clinics. Two index tests will be performed: patient reported bladder filling pain and bladder wall tenderness on internal pelvic bimanual examination. A final diagnosis of BPS will be made by expert consensus panel. We will assess the rates of index tests in women with CPP; evaluate the correlation between index tests and Pelvic Pain Urgency/ Frequency (PUF) questionnaire results; and determine index test sensitivity and specificity using a range of analytical methods. Assuming a 50% prevalence of BPS and an 80% power approximately 152 subjects will be required exclude sensitivity of < 55% at 70% sensitivity. Discussion The results of this test validation study will be used to identify whether a certain combination of signs and symptoms can accurately diagnose BPS. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF