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Introduction Recently scientific attention of Ukrainian narcology was focused on the group of new complex pharmacological preparations with polymodal pathogenic effect option (Cocarnit, World Medicine, Great Britain). Aims and objectives To ground feasibility of Cocarnit application in complex treatment of alcohol withdrawal syndrome (AWS). Method Eleven patients with alcohol addiction were examined. An integrated research of relieving and adjuvant effects of pharmacological preparation Cocarnit in complex with traditional detoxication therapy in clinical course of alcohol dependence at AWS stage was carried out. One to 2 ampoules of Cocarnit were injected intramuscularly once per 24 hrs, № 6. Methods Clinical-psychopathological, clinical-laboratory, consulting of specialists, methods of psychological investigation (CIWA; САН; SF-36) at day 1, 7 and 14 of treatment. Results AWS quantification score on admission was 41. Further therapeutic regress of all AWS components was registered. At day 1 the patient's condition started improving, clinical score was 32; at day 3 – 17; day 5 – the score was 13, insignificant tremor remained. At day 7 of treatment, practically complete relieving effect of the therapy was ascertained. With САН method at day 7 of the treatment, an increase of figures in all scales was registered: state of health 2.7, activity 2.4, mood 2.5. SF-36 method: at day 1 – the score was 24, day 7 – 32, day 14 – 49. Conclusions Thus, the developed by us method of integrated treatment with inclusion of Cocarnit for withdrawal state in alcohol addicts allows to stop acute signs of pathology within 3–5 days. [ABSTRACT FROM AUTHOR]

Introduction The work presents HIV PLEDGE project cooperative results of Kharkov Medical Academy of Postgraduate Education (KhMAPE) and the United Nations Office on Drugs and Crime (UNODC) in Ukraine which correspond the Law of Ukraine “On the Higher Education” requirements. Objectives and aims The project is aimed at the reduction of HIV-infection, tuberculosis and other comorbid disorders in drug addicts in Ukraine. The results are expected to be introduced into postgraduate training for doctors narcologists of Ukraine at the resource training centre (RTC) created under UNODC aegis according to innovation international education and technology standards criteria adapted for all forms of postgraduate training including medical residency. Methods Clinical, laboratory, epidemiological methods, statistical monitoring were applied for modern drug addiction conditions. Results The research allowed: – to increase abilities of KhMAPE departments to provide up-to-date epidemiological information for narcological diseases, pathophysiology, treatment, prevention, rehabilitation, HIV-linked medical and non-medical services integration in routine practice; – to approach renewed academic programs, distance training courses, certification, special modern software, computer technologies, internet resources; – to increase the postgraduate education efficiency and quality; – to apply up-to-date information concerning treatment; – to provide tuition and online training. RTC was equipped with special software, valid educational and diagnostic tests, e-libraries, research analytical reports, Tritnet educational and information materials, presentation setup. RTC provides monitoring system of academic efficiency “Smart Senteo”, distance training module program, database server “Osvita”. Conclusions RTC efficiency and prospects of new form of postgraduate medical training for doctors narcologists in residency have been grounded. [ABSTRACT FROM AUTHOR]