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Bala is located in Central Anatolia and is a sub-basin of the Tuzgölü basin, which consists of many basins formed in response to the closure of the Neotethys ocean. The evaporites in Bala sub-basin formed under the influence of regional uplifting during the Middle Eocene period with gradual shallowing in response to the structural compressional regime. The Bala sub-basin comprises four units from bottom to top: the Lower Unit (BU1) consisting of mudstone, claystone with limestone layers; the Evaporites (BU2) containing dominant gypsum with anhydrite; mixed siliciclastic-carbonate-evaporitic deposits (BU3); and the Upper Unit (BU4) containing conglomerate-sandstone-claystone and siltstones. The evaporitic unit, which are the main subject of study consists of primary selenitic gypsum, anhydrite, locally celestite crystals and secondary gypsum formed due to the anhydritization of primary gypsum and then hydration of these anhydrites. The results obtained from mineralogical-petrographic, geochemical and isotopic (δ18O and δ34S) investigations indicate that these evaporites were deposited in shallow marine to sabkha environments dominated by arid conditions. The presence of primary selenite crystals, the anhydrite with nodular, chicken-wire, and mosaic structures support precipitation occurred in a partially saline shallow water. The excessive thickness of the evaporitic accumulation, chaotic masses including gypsum breccia, salt diapirs and dome structures are attributed to tectonic processes acting during the formation of the Central Anatolian basins. [ABSTRACT FROM AUTHOR]

The Quaternary volcanic rocks from Gögova region constitute an example of on intra-continental volcanism in Southern Anatolia, Turkey. These rocks were erupted along the left-lateral strike-slip Yumurtalιk fault zone. They comprise basaltic lavas containing mafic enclaves. The enclaves are distributed widely through the lavas and are spherical to ellipsoidal in shape. Both the host lavas and the mafic enclaves have an alkaline character. Fractional crystallization process was important in the formation of the mafic enclaves where olivine was the main crystallizing phase. However, fractional crystallization was not a dominant process in the host lavas. Geochemical and petrological characteristics of both the mafic enclaves and the host lavas imply that magma mingling occurred during or immediately before eruption. [ABSTRACT FROM AUTHOR]

Diffuse pollution is usually temporally and spatially uncertain, and thus hard to analyze. In many cases, discretizing a diffuse source of pollution into individual point sources can ease diffuse pollution modelling and analysis, and therefore reduce high uncertainty especially in the spatial distribution of pollution loads. This is however a difficult task, since quite a number of sub-drainage areas, with complex structures and land-use properties, has to be delineated. Watershed models can be used to delineate the sub-drainage areas in a watershed with high accuracy and locate the related outlets which connect the sub- drainage areas to the main waterbody in a watershed. In this study, such an approach has been used on a case study to model the diffuse nutrient loads carried to streams that reach to a medium-sized lake in Turkey. The annual nutrient loads, which were calculated by using mathematical models, were then converted to a load-map with the help of a geographical information system. [ABSTRACT FROM AUTHOR]

Introduction: The aim of this study is to examine the effects of Ramadan fasting on melatonin, cortisol, and serotonin levels., Methods: In this study, the blood of 19 healthy male individuals between the ages of 26 and 51, registered in Agri (Turkey) Family Health Center and fasting during Ramadan, was studied. The study was carried out in 2021-2022. The SPSS-22 package program was used in the analysis of the data. Wilcoxon analysis was used in the study., Results: It was determined that the pre-test-post-test melatonin and cortisol levels of the individuals were not statistically significant (p>0.05). It was determined that the pre-test-post-test serotonin difference of the individuals was statistically significant (p<0.05)., Conclusion: It has been determined that Ramadan fasting increases the serotonin level of individuals but does not change the levels of melatonin and cortisol. It was determined that the level of happiness of individuals increased after Ramadan fasting. Longitudinal studies on the effects of Ramadan fasting are recommended., (© 2023. The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland.)

Background: This study aimed to determine the effect of rumination and elder abuse levels on successful aging in elderly individuals., Methods: This descriptive-correlational study was conducted with older individuals (n = 297) in Ağrı, Turkey, between October 2021 and May 2022. SPSS-22 and R v.4.1.3 were used in the study. Analysis was done with machine learning and artificial neural networks., Results: In the study, the mean age of the older individuals was 67.49 ± 3.04. Statistical estimates showed the regression model to be significant and usable, F(2,294) = 116.659, P = 0.001. Elder abuse and ruminative thought levels together explained 43.9% of the total variance (R 2  = 0.439) of successful aging. The regression model indicated that increases in both the elder abuse level (t = -3.672, P < 0.001) and the ruminative thought level (t = -12.771, P < 0.001) of participants caused a statistically significant decrease in the successful aging level. The combined elder abuse and ruminative thought levels had a greater effect on successful aging (Model 1: F = 45.321, Model 2: F = 116.659, R 2 Change = 0.309). The R 2 value of the Random Forest regression model was 0.529, showing that the independent variables could explain 52.92% of the variation in the dependent variable. According to the SHapley Additive exPlanation values, which show the contribution or importance of each variable in the estimation of the model, it was determined that the most important variables for estimating the Successful Aging Scale variable were ruminative thought style and elder abuse screening., Conclusions: Our study indicates that a decrease in the levels of rumination and elder abuse could lead to improvement in successful aging. Longitudinal studies on successful aging in older individuals are recommended., (© 2023 Japanese Psychogeriatric Society.)

The objective of the present study was to determine the plasma total oxidative status (TOS) and total antioxidant capacity (TAC) in patients with endemic fluorosis. A total of 79 (35 males and 44 females; mean age 44.0 ± 11.9 years) patients with endemic fluorosis and 55 (23 males and 32 females; mean age 48.3 ± 8.5 years) age-, sex- and body mass index-matched healthy controls were included in this study. The urine fluoride levels and plasma TOS and TAC levels were measured. The urine fluoride levels of fluorosis patients were significantly higher than control subjects as expected (1.91 ± 0.15 vs. 0.49 ± 0.13 mg/L, respectively; p < 0.001). TOS was significantly higher in fluorosis group than in control group (17.55 ± 3.82 vs. 15.06 ± 4.31 μmol H(2)O(2) Eq/L, respectively; p = 0.001). TAC was significantly lower in fluorosis group than in control group (1.60 ± 0.36 vs. 1.82 ± 0.51 mmol Trolox Eq/L, respectively; p = 0.004). Oxidative stress index (OSI) was significantly higher in fluorosis group than in control group (11.5 ± 3.8 vs. 8.8 ± 3.7, respectively; p < 0.001). Correlation analysis in all the groups indicated that TAC was negatively correlated with urine fluoride (r = -0.25, p = 0.003), TOS was positively correlated with urine fluoride (r = 0.34, p < 0.001) and OSI was positively correlated with urine fluoride (r = 0.36, p < 0.001). The results of our study demonstrate that oxidative stress plays an important role in the pathogenesis of the endemic fluorosis.

Watershed models, that enable the quantification of current and future pollution loading impacts, are essential tools to address the functions and conflicts faced in watershed planning and management. In this study, the Watershed Modeling System (WMS) version 7.1 was used for the delineation of boundaries of Koycegiz Lake-Dalyan Lagoon watershed located in the southwest of Turkey at the Mediterranean Sea coast. A Digital Elevation Model (DEM) was created for one of the major streams of the watershed, namely, Kargicak Creek by using WMS, and DEM data were further used to extract stream networks and delineate the watershed boundaries. Typical properties like drainage areas, characteristic length and slope of sub-drainage areas have also been determined to be used as model inputs in hydrological and diffuse pollution modeling. Besides, run-off hydrographs for the sub-drainages have been calculated using the Rational Method, which produces valuable data for calculating the time variable inflow and input pollution loads to be further utilized in the future water quality models of the Creek. Application of WMS in the study has shown that, it is capable to visualize the results in establishing watershed management strategies.

Objective: The aim of this study was to evaluate the QT intervals at different rest heart rates in healthy middle-aged Turkish men and to compare the known four QT adjusting methods for heart rate., Methods and Results: The QT intervals were measured in electrocardiograms of 210 healthy men (mean age = 35-60 years). A curve relating QT intervals and heart rates from 45 to 135 beats/min was constructed for study population. Based on the formula of Bazett, Fridericia, and Framingham, adjusted QT intervals in these range of heart rates were separately estimated. An adjusting nomogram for different heart rates was created using a reference value, which was the measured QT interval at heart rate of 60 beats/min (QT(No) = QT + correcting number). These four QT correction methods were compared with each other. The reference value of QT interval at heart rate of 60 beats/min was 382 ms. The relationship between QT and RR interval was linear (r = 0.66, P < 0.001). Nomogram method corrected QT interval most accurately for all the heart rates compared with other three adjusting methods. At heart rates of 60-100 beats/min, the equation of linear regression was QT = 237 + 0.158 x RR (P < 0.001). Bazett's formula gave the poorest results at all the heart rates. The formulas of Fridericia and Framingham were superior to Bazett's formula; however, they overestimated QT interval at heart rate of 60-110 beats/min (P < 0.01). At lower rates (<60 beats/min), all methods except nomogram method, underestimated QT interval (P = 0.03)., Conclusion: Among four QT correction formulas, the nomogram method provides the most accurately adjusted values of QT interval for all the heart rates in healthy men. Bazett's formula fails to adjust the QT interval for all the heart rates.