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Aim: Botulinum toxin injections are an important issue that is widely used, and many scientific articles have been published in patients with temporomandibular joint disorders (TMD). The aim of this study was to evaluate the status of activity the use of botulinum toxin in TMD during the period 1978-2023. Material and Methods: Articles published until April 1, 2023 were searched in Web of Science. The top 50 articles with the highest citations and suitable for the study topic were selected among the totally 299 articles. Results: Even though the articles published about botulinum injection in TMD have increased in recent years, there is no regular increase over the years. The most cited article was published in 2015 and the number of citations in Web of Science was 194. While there was no difference in productivity among the authors, the most productive country was the United States. Türkiye was found to be above the average among other countries. Conclusion: This bibliometric study of the top 50 most-cited papers in Web of Science the use of botulinum toxin in TMD recognized a quantitative and qualitative analysis of this very favorable research field. [ABSTRACT FROM AUTHOR]