1. PHYTOCHEMICAL ANALYSIS OF ACTIVE PHENOLIC COMPOUNDS IN SOME PLANTS USED AS TRADITIONAL FOLK DRUGS FOR CANCER AND LITERATURE REVIEW OF THEIR ANTI-CANCER EFFECTS.
- Author
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ARSLAN, İ. H., KAYA, Ö. F., and TOSYAGÜLÜ ÇELİK, H.
- Subjects
LITERATURE reviews ,PHYTOCHEMICALS ,PHENOLS ,ANTINEOPLASTIC agents ,CHEMICAL composition of plants ,CHRONIC myeloid leukemia - Abstract
In this study, the composition of the phenolic compounds for Malva neglecta, Nerium oleander, Quercus brantii and Vitis vinifera, that are registered as traditional folk remedy used for cancer during the ethnobotanical surveys conducted in Türkiye, were analyzed in phytochemical terms. Such analysis revealed very significant (p < 0.01) content of the phenolic compounds in the chemical composition of the plants, and then the effect sizes (χ2) thereof were determined. Thus, the anticancer effect potentials of the plants were established in line with the chemotherapeutic activities of the phenolic compounds, the probable efficacy of which has been demonstrated in the content of the plants, as confirmed by the literature review. The plants, that presented the highest anti-carcinogenic activity potential on 12 established types of cancer, were: Q. brantii in bladder cancer; M. neglecta, N. oleander, Q. brantii and V. vinifera in breast cancer; Q. brantii, and V. vinifera in cervical cancer; Q. brantii and V. vinifera in colorectal cancer; N. oleander in chronic myeloid leukemia; Q. brantii in glioblastoma multiforme; M. neglecta and V. vinifera in liver cancer; M. neglecta, Q. brantii, and V. vinifera in lung cancer; Q. brantii in mesothelioma; V. vinifera in ovarian cancer; M. neglecta, and Q. brantii in prostate cancer; M. neglecta in skin cancer. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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