Search

Aim: Echinococcosis, caused by Echinococcus species, is an important zoonotic disease causing major health problems in humans and animals. Herein, we aimed to evaluate the epidemiology, clinical and laboratory parameters, radiological, serological, pathological, and treatment protocols of followed-up cases of hydatidosis. Methods: A total of 550 patients diagnosed with hydatid cyst disease were included in this study. Patients who were positive for one or more of the enzyme-linked immunosorbent assay or indirect hemagglutination test, pathological results, or radiological findings were examined. The data analyzed were collected from nine centers between 2008 and 2020. Records were examined retrospectively. Results: Among the patients, 292 (53.1%) were women and 258 (46.9%) were men. The patients' mean age was 44.4 ± 17.4 years. A history of living in rural areas was recorded in 57.4% of the patients. A total of 435 (79.1%) patients were symptomatic. The most common symptoms were abdominal pain in 277 (50.4%), listlessness in 244 (44.4%), and cough in 140 (25.5%) patients. Hepatomegaly was found in 147 (26.7%), and decreased breath sounds were observed in 124 (22.5%) patients. Radiological examination was performed in all cases and serological methods were also applied to 428 (77.8%) patients. The most frequently applied serological test was IHA (37.8%). A single cyst has been found in 66% patients. Hepatic involvement occurred in 327 (59.4%), pulmonary involvement was found in 128 (23.3%), whereas both of them were recorded in 43 (7.8%) patients. Splenic involvement was only detected in nine (1.6%) patients. Echinococcus granulosus (72.5%) was most frequently detected. Cyst diameters of 56.9% of the patients were in the range of 5–10 cm. A total of 414 (75.2%) patients received albendazole as an antiparasitic. Mortality was noted in nine (1.6%) patients. Conclusion: Echinococcosis is an important public health problem in Turkey. It can affect the social, economic, and political structures of the community. Public education and awareness are extremely important. [ABSTRACT FROM AUTHOR]

Quaternary mafic lavas in Central Anatolia provide geochemical insights into melt generation processes following regional delamination of the subducted Tethyan slabs. New geochemical data from the Pleistocene Hasandağ Cinder Cone Province (HCCP) and Karapınar Volcanic Field (KVF) record contributions from subduction-modified lithospheric and sub-lithospheric source domains that are distinct from those sampled elsewhere across Anatolia (e.g., Pearce et al., 1990; Aldanmaz et al., 2006; Keskin, 2007; Chakrabarti et al., 2012; Reid et al., 2017). Hasandağ cinder cones are primarily basaltic, with subordinate trachybasalt and basaltic trachyandesite; Karapınar lavas comprise basalts and andesites with subordinate basaltic trachyandesite and basaltic andesite. Anomalously high Li, Na, Ti and Zr abundances and Ba/Rb values in these South-Central Anatolian primitive mafic lavas suggest significant contribution from metasomatic phases (i.e., amphibole, zircon and rutile); Dy/Yb n values measured in the mafic volcanics indicate melting in the spinel stability field. Correlation between 87Sr/86Sr and ε Nd in HCCP and KVF lavas indicate pseudo-binary mixing between enriched and depleted endmembers, while ε Nd -ε Hf isotopic values that plot above the terrestrial array extend toward sediment compositions sampled from the eastern Mediterranean Sea (Klaver et al., 2015). Together, trace element chemistry and Sr-Nd-Hf-Pb isotope compositions suggest input from a spatially heterogeneous mantle with contributions from depleted MORB-like and recycled sediment sources. The apparent presence of pyroxenite and hydrous metasomes within the HCCP and KVF source regions, and abundant dense mafic cumulates associated with the adjacent Hasandağ stratovolcano, support an unstable small-scale lithospheric density structure in South-Central Anatolia. We suggest regional delamination of the Neotethyan slab on a regional scale caused upwelling asthenosphere to destabilize the remaining Central Anatolian lithosphere and resulted in localized drip melting to produce the mafic volcanism at the HCCP and KVF. Geochemical similarities to Miocene alkali basalts from Galatia and Sivas (Wilson et al., 1997; Varol et al., 2014; Kürkcüoğlu et al., 2015) suggest that this mechanism occurred across Central Anatolia subsequent to Tethys subduction, and thus the ages of monogenetic volcanic activity record the descent of the slab beneath Anatolia. We infer that slab foundering played a more important role in this process than lithospheric loss beneath a tectonically shortened orogen (Göğüs et al., 2017) although further mapping of sedimentary basins and structures is required to resolve this interpretation. • Hasandag and Karapınar cinder cones represent small-volume mafic magma batches. • Sr-Nd-Hf-Pb isotopes require lithospheric and sub-lithospheric mantle domains. • Lithospheric mantle sources have been affected by sediment input. • Drip magmatism results from metasomatic pyroxenite and dense mafic cumulates. [ABSTRACT FROM AUTHOR]

Aim: Echinococcosis, caused by Echinococcus species, is an important zoonotic disease causing major health problems in humans and animals. Herein, we aimed to evaluate the epidemiology, clinical and laboratory parameters, radiological, serological, pathological, and treatment protocols of followed-up cases of hydatidosis. Methods: A total of 550 patients diagnosed with hydatid cyst disease were included in this study. Patients who were positive for one or more of the enzyme-linked immunosorbent assay or indirect hemagglutination test, pathological results, or radiological findings were examined. The data analyzed were collected from nine centers between 2008 and 2020. Records were examined retrospectively. Results: Among the patients, 292 (53.1%) were women and 258 (46.9%) were men. The patients' mean age was 44.4 ± 17.4 years. A history of living in rural areas was recorded in 57.4% of the patients. A total of 435 (79.1%) patients were symptomatic. The most common symptoms were abdominal pain in 277 (50.4%), listlessness in 244 (44.4%), and cough in 140 (25.5%) patients. Hepatomegaly was found in 147 (26.7%), and decreased breath sounds were observed in 124 (22.5%) patients. Radiological examination was performed in all cases and serological methods were also applied to 428 (77.8%) patients. The most frequently applied serological test was IHA (37.8%). A single cyst has been found in 66% patients. Hepatic involvement occurred in 327 (59.4%), pulmonary involvement was found in 128 (23.3%), whereas both of them were recorded in 43 (7.8%) patients. Splenic involvement was only detected in nine (1.6%) patients. Echinococcus granulosus (72.5%) was most frequently detected. Cyst diameters of 56.9% of the patients were in the range of 5-10 cm. A total of 414 (75.2%) patients received albendazole as an antiparasitic. Mortality was noted in nine (1.6%) patients. Conclusion: Echinococcosis is an important public health problem in Turkey. It can affect the social, economic, and political structures of the community. Public education and awareness are extremely important.