1. Painful ophthalmoplegia in a patient with a history of marginal zone lymphoma.
- Author
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Van Bogaert, C., Mathey, C., Vierasu, I., Trotta, N., Rocq, L., Wolfromm, A., De Wilde, V., and Goldman, S.
- Subjects
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MUCOSA-associated lymphoid tissue lymphoma , *COMPUTED tomography , *POSITRON emission tomography , *EYE paralysis , *DIAGNOSIS , *CAVERNOUS sinus - Abstract
A 73-year-old man with a history of marginal zone lymphoma was admitted to the emergency room for diplopia and ipsilateral headache. The Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) demonstrated intense and symmetrical hypermetabolism of the cavernous sinuses, and hypermetabolic lesions diffusely in the lymph nodes and bones. The diagnosis of high-grade relapse of lymphomatous disease was made. In this context, the homogenous and symmetric lesion of the cavernous sinuses, without any other encephalic or meningeal lesions, raised the hypothesis of a paraneoplastic origin. A plausible paraneoplastic link between the neuro-ophthalmological lesion and the malignant disorder is IgG4-related disease, a condition that may be associated with lymphoma. As in our case, this diagnosis is often presumptive because histopathological confirmation is difficult to obtain. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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