Search

The purest and unrestricted source of stem cells is the enamel of the teeth. Dental stem cells (DSCs), which are simple to get, quick to use, and reasonably priced, have the potential to be used in a variety of promising therapeutic applications. Due to their capacity for self-renewal, they are employed to treat significant flaws brought about by diseases, injuries, or surgical procedures. However, they are constrained by moral and ethical issues, as well as challenges with isolation, culturing, and implantation. DSCs are used in the rebuilding of orofacial structures because they retain the ability to differentiate into neurogenic, adipogenic, and odontogenic components. Before stem cell implantation, scaffolding that has been treated with growth hormones and bone morphogenic proteins is crucial. A self-administered questionnaire was used for a cross-sectional study (n = 200) that collected data on demographics, knowledge of stem cells, and attitude statements. Statistical Package for Social Software version 20.0 was used to analyze the data. This study seeks to learn more about professional groups' perceptions of stem cell research in Tamil Nadu and their knowledge and awareness of DSCs. [ABSTRACT FROM AUTHOR]

We assessed the groundwater quality in an industrial area (Tiruchendur Taluk) of Tamil Nadu state in coastal south India for human health risk from drinking as well as irrigation suitability by using the drinking water quality index (DWQI), irrigation factors (sodium adsorption ratio, sodium percentage, residual sodium carbonate and permeability index) and health hazard valuation (THQI- by consuming NO 3 − and F −). About 57% of the samples represented Ca2+-Mg2+-Cl−-SO 4 2− facies and the anthropological unhygienic inputs elevated the salinity. Our results indicated that all the samples are unsuitable for drinking (DWQI up to 1063) and almost half of them are also unsuitable for irrigation due to sodium risk. Total hazard quotient index (THQI; HQ nitrate and HQ fluoride) suggested the order of health risk as children > women > men with about 64%, 70% and 79% of the samples posing non-carcinogenic risks for men, women and children, respectively. Different mitigation measures and sustainable development should be enforced to minimize the health issues from contamination caused by industries, fertilizers in agro-fields and natural processes and reduce the sodium dominance in groundwater. The spatial distribution maps of this study could also be helpful in organization of proper treatment plans to provide safe and hygienic groundwater to the community. [Display omitted] • Three-dimensional approach (drinking water quality, irrigation and human health) of groundwater evaluation from south India. • DWQI based unsuitability of all samples for drinking. • Almost half of the samples are inappropriate for irrigation due to sodium risk. • HQ fluoride and HQ nitrate-based estimation of the low-risk range violation for men, women and children. [ABSTRACT FROM AUTHOR]